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A large grant for exporing the epigenetics in diabetes

Charlotte Ling, researcher at Lund University Diabetes Centre, receives this year´s Novo Nordisk Foundation Excellence Project grant, five millions Danish crowns allocated during five years. Her project is about exploring whether epigenetic factors are underlying the development of Type 2 Diabetes.

- This means very much to me and my research group. We will be able to expand and it will speed up the research process, says Charlotte Ling.
Novo Nordisk Foundation Excellence Project grant can be applied for by researchers active in a nordic country and the projects should be of high international standard. Charlotte Ling´s project is about epigenetics, about the link between inheritance and environment. Modern research has shown that the genome we are born with is affected during life so the outcome will be another. Examples of factors which may cause epigenetic changes are diet, exercise and medicines.
Usual forms of epigenetic changes are metylations, a small chemical modification which affects the process of when and how different genes will be activated.
- In our project we will investigate whether DNA metylations underlies the impaired insulin secretion in patients who suffers from type 2 Diabetes compared to healthy individuals, says Charlotte Ling and adds:
- The aim is to identify new mechanisms behind Type 2 Diabetes.

During the past four years three of the recipients of the Novo Nordisk Foundation Excellence Project grant come from Lund University Diabetes Centre; Nils Wierup 2008, Anders Rosengren 2010 and this year Charlotte Ling.

Link to charlotte Ling´s research group Epigenetics and Diabetes

https://www.ludc.lu.se/research-units/epigenetics-and-diabetes