Prize winner 2014
Professor of Integrative Physiology at Karolinska Institute, Department of Physiology and Pharmacology.
Professor Anna Krook is awarded the prize for her groundbreaking work in the area of insulin action in skeletal muscle. The rationale for these important studies is that most of the carbohydrates ingested with a meal are transported into skeletal muscle cells. This process is perturbed in insulin resistant individuals - a crucial aspect of Type 2 Diabetes.
Professor Krook's work has been particularly important since she has studied these mechanisms both in elegant animal models and in human skeletal muscle. This translational approach has revealed the importance of transcription factors and cytokines as well as DNA methylation for insulin action.