Jun
BEAt-DKD symposium – "Successful stories, lessons learned and what’s next?"
Welcome to the BEAt-DKD Symposium “Successful stories, lessons learned and what’s next?”.
BEAt-DKD (Biomarker Enterprise to Attack Diabetic Kidney Disease) is a public-private partnership under the auspices of Innovative Medicines Initiative (IMI), which has worked for the past seven years to improve patient stratification, to identify targetable mechanisms and pathways underlying DKD and to identify and validate biomarkers of disease progression and treatment response. The overall aim of the project has been to advance the field towards precision medicine in the management of DKD.
The work to be presented at the symposium is the result of the collaborative effort of 33 partners from academia, industry and one patient organisation, with funding support from the European Commission, the European Federation of Pharmaceutical Industries and Associations, and JDRF. The project is coordinated by Lund University.
Please register for live or online participation with Ulrika Blom-Nilsson.
Email address: ulrika [dot] blom-nilsson [at] med [dot] lu [dot] se
Programme
08.00 – 09.00
Registration and coffee
09.00 – 09.30
Welcome and introduction by BEAt-DKD coordinator Maria F. Gomez, Lund University and EFPIA project leader Kevin Duffin, Eli Lilly
Highlights from the BEAt-DKD program (session one)
Moderators: Matthias Kretzler, University of Michigan and Kevin Duffin, Eli Lilly
09.30 – 09.50
Biomarker candidates of DKD progression
Andreas Heinzel and Michael Kammer, Medical University Vienna
09.50 – 10.10
Urine EVs as potential “liquid kidney biopsy” – early non-invasive markers of DKD
Maija Puhka, University of Helsinki
10.10 – 10.30
Integrative transcriptome and proteome profiling of human insulin-resistant kidney cell lines and biopsies in DKD
Richard Coward, University of Bristol
10.30 – 10.50
Cell-specific molecular programs of DKD
Tobias Huber, University Clinic Hamburg-Eppendorff
10.50 – 11.10
Endothelial Glycocalyx as therapeutic target in DKD
Simon Satchell, University of Bristol
11.10 – 11.40
Elevator pitch competition: junior researchers present their activities in BEAt-DKD – voting by the audience
Moderators: Viji Nair, University of Michigan and Frédéric Burdet, Swiss Institute for Bioinformatics
11.40 – 12.30
Light lunch
Highlights from the BEAt-DKD program (session two)
Moderators: Mark Ibberson, Swiss Institute for Bioinformatics and Maria F. Gomez, Lund University
12.30 – 12.50
Prognostic imaging biomarkers for DKD: The iBEAt study
Steven Sourbron, University of Sheffield and Kim Gooding, University of Exeter
12.50 – 13.10
A novel classification of renal damage in diabetes: Preliminary results from iBEAt ancillary-study
Paola Pontrelli and Loreto Gesualdo, University of Bari
13.10 – 13.30
Pharmacodynamic response urinary markers for atrasentan and canagliflozin
Wenjun Ju, University of Michigan
13.30 – 13.45
PRIME-CKD: building on BEAt-DKD outcomes
Hiddo Lambers-Heerspink, University Medical Centre Groningen, Sharon Stapleton, Renalytix AI Ltd
13.45 – 14.00
The Kidney Precision Medicine Project (KPMP) – mutual inspiration and interactions with BEAt-DKD
Matthias Kretzler, University of Michigan
14.00 – 14.20
Federated databases bring your analyses to the data – experiences from BEAt-DKD and beyond
Mark Ibberson, Swiss Institute for Bioinformatics
14.20 – 14.40
Reviewing regulatory endorsement of biomarkers and our experiences with the PRE score qualification
Peter Mol, University Medical Centre Groningen
14.40 – 15.00
Coffee break
15.00 – 15.20
BEAt-DKD recap – perspectives from BEAt-DKD Scientific Advisory Board members
Mark Cooper, Monash University, Australia and Aimo Kant, Frauenhofer Institute for Molecular Biology and Applied Ecology
15.20 – 16.15
Panel discussion “Present and future directions in DKD”
Lars Johansson (Antaros Medical AB), Peter Mol (UMCG/EMA), Aliza Thompson (FDA/BEAt-DKD Scientific Advisory Board member)
Moderators: Kevin Duffin and Maria F. Gomez
16.15 – 16.30
Award for best elevator pitch
Closing remarks
About the event
Location:
Jubileumsaulan, SUS, Jan Waldenströms gata 5, 214 28 Malmö, or online
Contact:
ulrika [dot] blom-nilsson [at] med [dot] lu [dot] se