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Population studies

Population-based studies that contain data och health and diseases are an important source of knowledge for diabetes researchers. On this webpage you will find information about some population studies that are relevant for researchers in the diabetes field. Researchers affiliated with LUDC have been involved in most of the studies listed below.

Researchers at LUDC have a long tradition of carrying out population studies. Below, you will find a list of population studies that are relevant to researchers in the diabetes field. Researchers affiliated with LUDC and the strategic research area EXODIAB (Excellence of Diabetes Research in Sweden) have been involved in most of the studies listed below. 

Please contact representatives for the different studies if you would like to access data from the studies for your research projects. The links will forward you to other websites.

ANDIS (All New Diabetics in Skåne)

The research project All New Diabetics in Skåne (ANDIS) started in 2008 with the aim of registering all new cases of diabetes diagnosed in the region. One of the population study’s objectives is to contribute to improving the diagnosis and treatment of various types of diabetes.

The ANDIS website (andis.lu.se)

Malmö Preventive Project (MPP)

This study recruited 22,000 men and 11,000 women between 1974 and 1991. The baseline survey contained a questionnaire that mainly addressed lifestyle and socio-economic factors. All participants submitted a blood test and underwent a physical examination to measure blood pressure, height, and weight, and evaluate lung function by spirometry.

The Malmö Preventive Project (malmo-kohorter.lu.se)

The Malmö Diet Cancer Study (MDC)

In the early 1990s, the Swedish Cancer Foundation initiated a large cohort study with the primary goal of investigating the relationship between diet and subsequent cancer risk. Between 1991 and 1996, 17,000 women and 11,000 men were recruited. MDC is part of EPIC – The European Prospective Investigation into Diet and Cancer. This collaboration involves about 20 similar cohorts in ten European countries. Extensive genetic materials have become available through Professor Olle Melander.

Malmö Diet Cancer (MDC) (malmo-kohorter.lu.se)

Malmö Offspring Study (MOS)

The Malmö Offspring Study, MOS (Malmö Family Study) is a health survey that aims to map family patterns behind, for example, cardiovascular disease and diabetes. Children and grandchildren of participants in the Malmö Diet Cancer Study (MDC) were invited to participate. An important objective with the study is to follow how diseases cluster within a particular family, both through hereditary causes and lifestyle factors. Participants are also offered a free and painless examination of their dental health at within the study Malmö Offspring Dental Study (MODS).

Malmo Offspring Study (malmo-kohorter.lu.se)

Better Diabetes Diagnosis (BDD)

The Swedish Better Diabetes Diagnosis (BDD) study collects detailed information and blood samples from more than 7,000 children and adolescents with newly diagnosed diabetes. The discrimination between type 1 and type 2 diabetes is improved by means of HLA, diabetes autoantibodies and C-peptide.

BDD in Lund University's research portal
 

Diabetes Prediction in Skåne Study (DiPiS)

The aim of the Diabetes Prediction in Skåne Study is to identify genetic and immunological markers that predict clinical onset of type 1 diabetes and associated immune mediated diseases. Children at increased genetic risk have been followed until 15 years of age.

DiPiS in Lund University's research portal

TEDDY 

TEDDY (The Environmental Determinants of Diabetes in the Young) is a research project on what causes children to develop type 1 diabetes. The study is being conducted in Sweden, Finland, the USA, and Germany. In total, 8,667 children are included in the study, which is financed by the American National Institutes of Health (NIH). The project began in 2004 and will continue until 2025.

The TEDDY study website (teddy.lu.se)

The Global Platform for the Prevention of Autoimmune Diabetes (GPPAD)

The Global Platform for the Prevention of Autoimmune Diabetes (GPPAD) was launched in 2015 and brings together several academic research institutions and hospitals in Europe. The GPPAD studies focus on preventing beta cell autoimmunity, which is a mistaken reaction of the immune system that causes type 1 diabetes. GPPAD makes data and biomaterials from its studies available to other scientists for scientific collaborative projects. Data and biomaterials are collected in the following ongoing studies Primary Oral Insulin Trial (POInT), SINT1A, and a study that screens newborn with genetic risk score for type 1 diabetes.

International website GPPAD (gppad.org.de-en)

Swedish website GPPAD (gppad.lu.se)

The Swedish CArdioPulmonary bioImage Study (SCAPIS)

The Swedish CArdioPulmonary bioImage Study – SCAPIS – is a nationwide, open-access, population-based cohort for the study of cardiovascular disease (CVD) and chronic obstructive pulmonary disease (COPD). The aim is to predict and prevent cardiovascular and pulmonary disease. A total of 30,154 men and women in Sweden, from 50 to 64 years old, have been recruited and investigated with detailed imaging and functional analyses of the cardiovascular and pulmonary systems. All researchers based in Sweden, or international researchers in collaboration with an applicant based in Sweden, are welcome to apply for data.

The SCAPIS website (scapis.org)

The Botnia Study

The Botnia Study was initiated by LUDC researcher Leif Groop and is led by Tiinnamaija Tuomi at University of Helsinki. The aim of this study is to characterise the genetic and environmental factors predisposing to diabetes and its complications. In addition to unraveling the complex interacting metabolic pathways, the researchers hope to find tools for individualised prevention and treatment of diabetes. Several clinical studies have been initiated as part of the Botnia Study, for example Botnia Family Study and Botnia Prospective Study and PPP Botnia study. You can find more information through the Botnia Study website.

The Botnia Study (helsinki.fi)