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Valeriya Lyssenko

Publications

Retrieved from Lund University's publications database

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Publications

Retrieved from Lund University's publications database

2019
- A diabetes-associated genetic variant is associated with diastolic dysfunction and cardiovascular disease
  John Molvin, Amra Jujic, Peter M Nilsson, Margret Leosdottir, Ulf Lindblad, et al.
  (2019) ESC Heart Failure
  Journal article
- Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls
  Jason Flannick, Valeriya Lyssenko, Leif Groop, Peter Nilsson, Michael Boehnke
  (2019) Nature
  Journal article
- Multiethnic Genome-Wide Association Study of Diabetic Retinopathy Using Liability Threshold Modeling of Duration of Diabetes and Glycemic Control
  Samuela Pollack, Leif Groop, Emma Ahlqvist, Valeriya Lyssenko, Elisabet Agardh, et al.
  (2019) Diabetes
  Journal article
2018
- A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes
  Natalie R van Zuydam, Emma Ahlqvist, Claes Ladenvall, Peter Almgren, Christina-Alexandra Schulz, et al.
  (2018) Diabetes
  Journal article
- A genome-wide association study suggests new evidence for an association of the NADPH Oxidase 4 (NOX4) gene with severe diabetic retinopathy in type 2 diabetes
  Weihua Meng, Kaanan P. Shah, Samuela Pollack, Iiro Toppila, Harry L. Hebert, et al.
  (2018) Acta Ophthalmologica
  Journal article
- Characteristics and prognosis of healthy severe obesity (HSO) subjects - The Malmo Preventive Project
  Maximilian Tremmel, Valeriya Lyssenko, Bengt Zöller, Gunnar Engström, Martin Magnusson, et al.
  (2018) Obesity Medicine
  Journal article
2017
- An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans
  Robert A. Scott, Laura J Scott, Reedik Mägi, Letizia Marullo, Kyle J Gaulton, et al.
  (2017) Diabetes
  Journal article
- Data Descriptor: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls
  Jason Flannick, Christian Fuchsberger, Anubha Mahajan, Tanya M Teslovich, Vineeta Agarwala, et al.
  (2017) Scientific Data
  Journal article
- Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis
  Eleanor Wheeler, Aaron Leong, Ching-Ti Liu, Marie-France Hivert, Rona J. Strawbridge, et al.
  (2017) PLoS Medicine
  Journal article
- Sense of Coherence is associated with LDL-cholesterol in patients with type 1 diabetes – The PROLONG-Steno study
  Kasper Olesen, Troels Mygind Jensen, Lars Jorge Diaz, Anne Cathrine Laustrup Møller, Ingrid Willaing, et al.
  (2017) Journal of Clinical and Translational Endocrinology
  Journal article
2016
- A Variant of GJD2, Encoding for Connexin 36, Alters the Function of Insulin Producing β-Cells.
  Valentina Cigliola, Celine Populaire, Ciro L Pierri, Samuel Deutsch, Jacques-Antoine Haefliger, et al.
  (2016) PLoS ONE
  Journal article
- A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape
  Janina S. Ried, Janina M. Jeff, Audrey Y. Chu, Jennifer L. Bragg-Gresham, Jenny Van Dongen, et al.
  (2016) Nature Communications
  Journal article
- Atrial Natriuretic Peptide in the high normal range is associated with lower prevalence of insulin resistance.
  Amra Jujic, Peter Nilsson, Margaretha Persson, Jens Juul Holst, Signe Sørensen Torekov, et al.
  (2016) The Journal of clinical endocrinology and metabolism
  Journal article
- CART is overexpressed in human type 2 diabetic islets and inhibits glucagon secretion and increases insulin secretion
  Mia Abels, Matteo Riva, Hedvig Bennet, Emma Ahlqvist, Oleg Dyachok, et al.
  (2016) Diabetologia
  Journal article
- From association to function : MTNR1B
  Amélie Bonnefond, Valeriya Lyssenko
  (2016) The Genetics of Type 2 Diabetes and Related Traits: Biology, Physiology and Translation
  Book chapter
- Genetic predisposition for beta cell fragility underlies type 1 and type 2 diabetes
  James Dooley, Lei Tian, Susann Schonefeldt, Viviane Delghingaro-Augusto, Josselyn E Garcia-Perez, et al.
  (2016) Nature Genetics
  Journal article
- Glucose-Dependent Insulinotropic Polypeptide (GIP) Stimulates Osteopontin Expression in the Vasculature via Endothelin-1 and CREB.
  Lisa Berglund, Valeriya Lyssenko, Claes Ladenvall, Olga Kotova, Andreas Edsfeldt, et al.
  (2016) Diabetes
  Journal article
- Glucose-dependent insulinotropic polypeptide (GIP) and GIP receptor (GIPR) genes : An association analysis of polymorphisms and bone in young and elderly women
  Gaurav Garg, Fiona E. McGuigan, Jitender Kumar, Holger Luthman, Valeriya Lyssenko, et al.
  (2016) Bone Reports
  Journal article
- Impact of the tcf7l2 genotype on risk of hypoglycaemia and glucagon secretion during hypoglycaemia
  Peter L. Kristensen, Ulrik Pedersen-Bjergaard, Rikke Due-Andersen, Thomas Høi-Hansen, Lise Grimmeshave, et al.
  (2016) Endocrine Connections
  Journal article
- Personalized therapy by phenotype and genotype
  Valeriya Lyssenko, Cristina Bianchi, Stefano Del Prato
  (2016) Diabetes Care
  Journal article
- The genetic architecture of type 2 diabetes
  Christian Fuchsberger, Tibor V. Varga, Claes Ladenvall, Jasmina Kravic, Paul Franks, et al.
  (2016) Nature
  Journal article
2015
- Age- and Sex-Specific Causal Effects of Adiposity on Cardiovascular Risk Factors.
  Tove Fall, Sara Hägg, Alexander Ploner, Reedik Mägi, Krista Fischer, et al.
  (2015) Diabetes
  Journal article
- Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation.
  Momoko Horikoshi, Reedik Mӓgi, Martijn van de Bunt, Ida Surakka, Antti-Pekka Sarin, et al.
  (2015) PLoS Genetics
  Journal article
- Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci.
  Kyle J Gaulton, Teresa Ferreira, Yeji Lee, Anne Raimondo, Reedik Mägi, et al.
  (2015) Nature Genetics
  Journal article
- Genetic studies of body mass index yield new insights for obesity biology.
  Adam E Locke, Bratati Kahali, Sonja I Berndt, Anne E Justice, Tune H Pers, et al.
  (2015) Nature
  Journal article
- Genetics of type 2 diabetes : It matters from which parent we inherit the risk
  Valeriya Lyssenko, Leif Groop, Rashmi B. Prasad
  (2015) Review of Diabetic Studies
  Journal article review
- Modelling of OGTT curve identifies 1 h plasma glucose level as a strong predictor of incident type 2 diabetes: results from two prospective cohorts
  Akram Alyass, Peter Almgren, Mikael Åkerlund, Jonathan Dushoff, Bo Isomaa, et al.
  (2015) Diabetologia
  Journal article
- New genetic loci link adipose and insulin biology to body fat distribution.
  Dmitry Shungin, Thomas W Winkler, Damien C Croteau-Chonka, Teresa Ferreira, Adam E Locke, et al.
  (2015) Nature
  Journal article
- The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.
  Thomas W Winkler, Anne E Justice, Mariaelisa Graff, Llilda Barata, Mary F Feitosa, et al.
  (2015) PLoS Genetics
  Journal article
- The impact of low-frequency and rare variants on lipid levels.
  Ida Surakka, Momoko Horikoshi, Reedik Mägi, Antti-Pekka Sarin, Anubha Mahajan, et al.
  (2015) Nature Genetics
  Journal article
- Using genetic variants to assess the relationship between circulating lipids and type 2 diabetes.
  Tove Fall, Weijia Xie, Wenny Poon, Hanieh Yaghootkar, Reedik Mägi, et al.
  (2015) Diabetes
  Journal article
- Variation in Glucose Homeostasis Traits Associated With P2RX7 Polymorphisms in Mice and Humans
  Jennifer N. Todd, Wenny Poon, Valeriya Lyssenko, Leif Groop, Brendan Nichols, et al.
  (2015) Journal of Clinical Endocrinology and Metabolism
  Journal article
2014
- A Central Role for GRB10 in Regulation of Islet Function in Man.
  Inga Prokopenko, Wenny Poon, Reedik Mägi, Rashmi Prasad, S Albert Salehi, et al.
  (2014) PLoS Genetics
  Journal article
- Genetics of diabetes complications.
  Sami Alkayyali, Valeriya Lyssenko
  (2014) Mammalian Genome
  Journal article
- Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility
  Anubha Mahajan, Min Jin Go, Weihua Zhang, Jennifer E. Below, Kyle J. Gaulton, et al.
  (2014) Nature Genetics
  Journal article
2013
- A link between GIP and osteopontin in adipose tissue and insulin resistance.
  Emma Ahlqvist, Peter Osmark, Tiina Kuulasmaa, Kasper Pilgaard, Bilal Omar, et al.
  (2013) Diabetes
  Journal article
- Assessing the phenotypic effects in the general population of rare variants in genes for a dominant Mendelian form of diabetes
  Jason Flannick, Nicola L. Beer, Alexander G. Bick, Vineeta Agarwala, Janne Molnes, et al.
  (2013) Nature Genetics
  Journal article
- Early Metabolic Markers of the Development of Dysglycemia and Type 2 Diabetes and Their Physiological Significance
  Ele Ferrannini, Andrea Natali, Stefania Camastra, Monica Nannipieri, Andrea Mari, et al.
  (2013) Diabetes
  Journal article
- Effect of Common Genetic Variants Associated with Type 2 Diabetes and Glycemic Traits on α- and β-cell Function and Insulin Action in Man.
  Anna Jonsson, Claes Ladenvall, Tarunveer Singh Ahluwalia, Jasmina Kravic, Ulrika Krus, et al.
  (2013) Diabetes
  Journal article
- Genetic Screening for the Risk of Type 2 Diabetes. Worthless or valuable?
  Valeriya Lyssenko, Markku Laakso
  (2013) Diabetes Care
  Journal article
- Genetic Variants Associated With Glycine Metabolism and Their Role in Insulin Sensitivity and Type 2 Diabetes
  Weijia Xie, Andrew R. Wood, Valeriya Lyssenko, Michael N. Weedon, Joshua W. Knowles, et al.
  (2013) Diabetes
  Journal article
- The Role of Adiposity in Cardiometabolic Traits: A Mendelian Randomization Analysis
  Tove Fall, Sara Hagg, Reedik Maegi, Alexander Ploner, Krista Fischer, et al.
  (2013) PLoS Medicine
  Journal article
- The human L-type calcium channel Ca(v)1.3 regulates insulin release and polymorphisms in CACNA1D associate with type 2 diabetes.
  Thomas Reinbothe, Sami Alkayyali, Emma Ahlqvist, Tiinamaija Tuomi, Bo Isomaa, et al.
  (2013) Diabetologia
  Journal article
2012
- A common variant upstream of the PAX6 gene influences islet function in man.
  Emma Ahlqvist, Fabiola Turrini, Stefan Lang, Jalal Taneera, Yuedan Zhou, et al.
  (2012) Diabetologia
  Journal article
- A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance
  Alisa K. Manning, Marie-France Hivert, Robert A. Scott, Jonna L. Grimsby, Nabila Bouatia-Naji, et al.
  (2012) Nature Genetics
  Journal article
- A systems genetics approach identifies genes and pathways for type 2 diabetes in human islets.
  Jalal Taneera, Stefan Lang, Amitabh Sharma, Joao Fadista, Yuedan Zhou, et al.
  (2012) Cell Metabolism
  Journal article
- Codon 72 polymorphism (rs1042522) of TP53 is associated with changes in diastolic blood pressure over time
  Erwin Reiling, Valeriya Lyssenko, Jolanda M. A. Boer, Sandra Imholz, W. Monique M. Verschuren, et al.
  (2012) European Journal of Human Genetics
  Journal article
- Common variant in the HMGA2 gene increases susceptibility to nephropathy in patients with type 2 diabetes.
  Sami Alkayyali, M Lajer, H Deshmukh, Emma Ahlqvist, H Colhoun, et al.
  (2012) Diabetologia
  Journal article
- Effect of a common variant of the PCSK2 gene on reduced insulin secretion.
  Anna Jonsson, B Isomaa, Tiinamaija Tuomi, Jonas Eriksson, Leif Groop, et al.
  (2012) Diabetologia
  Journal article
- Genetic Variation in the Glucose-Dependent Insulinotropic Polypeptide Receptor Modifies the Association between Carbohydrate and Fat Intake and Risk of Type 2 Diabetes in the Malmo Diet and Cancer Cohort.
  Emily Sonestedt, Valeriya Lyssenko, Ulrika Ericson, Bo Gullberg, Elisabet Wirfält, et al.
  (2012) The Journal of clinical endocrinology and metabolism
  Journal article
- Genetic prediction of postpartum diabetes in women with gestational diabetes mellitus
  Magnus Ekelund, Nael Shaat, Peter Almgren, Eva Anderberg, Mona Landin-Olsson, et al.
  (2012) Diabetes Research and Clinical Practice
  Journal article
- Kartläggning av skyddsfaktorer vid typ 1-diabetes har börjat. Vissa patienter tycks skyddade mot sena komplikationer--flera studier pågår.
  Valeriya Lyssenko, Peter Nilsson
  (2012) Läkartidningen
  Journal article
- Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
  Andrew P. Morris, Benjamin F. Voight, Tanya M. Teslovich, Teresa Ferreira, Ayellet V. Segre, et al.
  (2012) Nature Genetics
  Journal article
- No Interactions Between Previously Associated 2-Hour Glucose Gene Variants and Physical Activity or BMI on 2-Hour Glucose Levels
  Robert A. Scott, Audrey Y. Chu, Niels Grarup, Alisa K. Manning, Marie-France Hivert, et al.
  (2012) Diabetes
  Journal article
- Reduced Insulin Exocytosis in Human Pancreatic β-cells With Gene Variants Linked to Type 2 Diabetes.
  Anders Rosengren, Matthias Braun, Taman Mahdi, Sofia A Andersson, Mary E Travers, et al.
  (2012) Diabetes
  Journal article
- Regulation of the pro-inflammatory cytokine osteopontin by GIP in adipocytes - A role for the transcription factor NFAT and phosphodiesterase 3B.
  Bilal Omar, Elin Banke, Emilia Guiguis, Lina Kesson, Vincent Manganiello, et al.
  (2012) Biochemical and Biophysical Research Communications
  Journal article
- Secreted frizzled-related protein 4 reduces insulin secretion and is overexpressed in type 2 diabetes.
  Taman Mahdi, Sonja Hänzelmann, S Albert Salehi, Sarheed Jabar Muhammed, Thomas Reinbothe, et al.
  (2012) Cell Metabolism
  Journal article
- Tired of Diabetes Genetics? Circadian Rhythms and Diabetes: The MTNR1B Story?
  Cecilia Nagorny, Valeriya Lyssenko
  (2012) Current Diabetes Reports
  Journal article
- Validation of a multi-marker model for the prediction of incident type 2 diabetes mellitus: Combined results of the Inter99 and Botnia studies.
  Valeriya Lyssenko, Torben Jørgensen, Robert W Gerwien, Torben Hansen, Michael W Rowe, et al.
  (2012) Diabetes & Vascular Disease Research
  Journal article
2011
- A common variant in TFB1M is associated with reduced insulin secretion and increased future risk of type 2 diabetes.
  Thomas Koeck, Anders H Olsson, Marloes Dekker Nitert, Vladimir Sharoyko, Claes Ladenvall, et al.
  (2011) Cell Metabolism
  Journal article
- Association between parental history of diabetes and type 2 diabetes genetic risk scores in the PPP-Botnia and Framingham Offspring Studies
  Jason L. Vassy, Peter Shrader, Anna Jonsson, Caroline S. Fox, Valeriya Lyssenko, et al.
  (2011) Diabetes Research and Clinical Practice
  Journal article
- FTO, Type 2 Diabetes, and Weight Gain Throughout Adult Life A Meta-Analysis of 41,504 Subjects From the Scandinavian HUNT, MDC, and MPP Studies
  Jens K. Hertel, Stefan Johansson, Emily Sonestedt, Anna Jonsson, Rolv T. Lie, et al.
  (2011) Diabetes
  Journal article
- Genome-Wide Association Identifies Nine Common Variants Associated With Fasting Proinsulin Levels and Provides New Insights Into the Pathophysiology of Type 2 Diabetes
  Rona J. Strawbridge, Josee Dupuis, Inga Prokopenko, Adam Barker, Emma Ahlqvist, et al.
  (2011) Diabetes
  Journal article
- Heritability and familiality of type 2 diabetes and related quantitative traits in the Botnia Study.
  Peter Almgren, M Lehtovirta, B Isomaa, L Sarelin, M R Taskinen, et al.
  (2011) Diabetologia
  Journal article
- Pleiotropic Effects of GIP on Islet Function Involve Osteopontin
  Valeriya Lyssenko, Lena Eliasson, Olga Kotova, Kasper Pilgaard, Nils Wierup, et al.
  (2011) Diabetes
  Journal article
- Power in the Phenotypic Extremes: A Simulation Study of Power in Discovery and Replication of Rare Variants
  Lin T. Guey, Jasmina Kravic, Olle Melander, Noel P. Burtt, Jason M. Laramie, et al.
  (2011) Genetic Epidemiology
  Journal article
2010
- A common variant in the PAX6 gene influences islet function in man
  Emma Ahlqvist, Fabiola Turrini, Stefan Lang, Targ Elgzyri, Yuedan Zhou, et al.
  (2010) Diabetologia
  Conference paper: abstract
- A family history of diabetes is associated with reduced physical fitness in the Prevalence, Prediction and Prevention of Diabetes (PPP)-Botnia study
  B. Isomaa, B. Forsen, K. Lahti, N. Holmstrom, J. Waden, et al.
  (2010) Diabetologia
  Journal article
- A meta-analysis of GWA blood glucose after 2 h of OGTT revealed that GIPR is associated with the secretion of insulin based on glucose and ADCY5 is a new susceptibility gene for type 2 diabetes.
  N. Bouatia-Naji, R. Saxena, M. F. Hivert, C. Langenberg, T. Tanaka, et al.
  (2010) Diabetes & Metabolism
  Conference paper: abstract
- Analysis of TBC1D4 in patients with severe insulin resistance
  S. Dash, C. Langenberg, K. A. Fawcett, R. K. Semple, S. Romeo, et al.
  (2010) Diabetologia
  Journal article (letter)
- Detailed Physiologic Characterization Reveals Diverse Mechanisms for Novel Genetic Loci Regulating Glucose and Insulin Metabolism in Humans
  Erik Ingelsson, Claudia Langenberg, Marie-France Hivert, Inga Prokopenko, Valeriya Lyssenko, et al.
  (2010) Diabetes
  Conference paper
- Effect of variants in the RORA gene on risk of type 2 diabetes
  Anna Jonsson, Sami Alkayyali, B. Isomaa, T. Tuomi, Leif Groop, et al.
  (2010) Diabetologia
  Conference paper: abstract
- GAD Antibody Positivity Predicts Type 2 Diabetes in an Adult Population
  Virve M. Lundgren, Bo Isomaa, Valeriya Lyssenko, Esa Laurila, Pasi Korhonen, et al.
  (2010) Diabetes
  Journal article
- Genetic susceptibility for obesity increases the risk of type 2 diabetes and is modified by macronutrient intakes
  Gull Rukh, Emily Sonestedt, Valeriya Lyssenko, Amitabh Sharma, Olle Melander, et al.
  (2010) Diabetologia
  Conference paper: abstract
- Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge
  Richa Saxena, Marie-France Hivert, Claudia Langenberg, Toshiko Tanaka, James S. Pankow, et al.
  (2010) Nature Genetics
  Journal article
- Genome wide association analysis for free fatty acid levels in DGI
  Ivana Stojkovic, C. Saloranta, Peter Almgren, Valeriya Lyssenko, E. Laurila, et al.
  (2010) Diabetologia
  Conference paper: abstract
- Influence of novel genetic loci affecting glucose and insulin levels during OGTT on islet function in man
  Tarun Ahluwalia, Claes Ladenvall, Anna Jonsson, Jasmina Kravic, Esa Laurila, et al.
  (2010) Diabetologia
  Conference paper: abstract
- Minimal Contribution of Fasting Hyperglycemia to the Incidence of Type 2 Diabetes in Subjects With Normal 2-h Plasma Glucose
  Muhammad A. Abdul-Ghani, Michael P. Stern, Valeriya Lyssenko, Tiinamaija Tuomi, Leif Groop, et al.
  (2010) Diabetes Care
  Journal article
- New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
  Josee Dupuis, Claudia Langenberg, Inga Prokopenko, Richa Saxena, Nicole Soranzo, et al.
  (2010) Nature Genetics
  Journal article
- Polymorphisms in CACNA1D affect insulin release and channel expression and associate with type 2 diabetes
  Thomas Reinbothe, Valeriya Lyssenko, Stefan Lang, Erik Renström
  (2010) Diabetologia
  Conference paper: abstract
- The shape of plasma glucose concentration curve during OGTT predicts future risk of type 2 diabetes
  Muhammad A. Abdul-Ghani, Valeriya Lyssenko, Tiinamaija Tuomi, Ralph A. DeFronzo, Leif Groop
  (2010) Diabetes/Metabolism Research Reviews
  Journal article
- Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis
  Benjamin F. Voight, Laura J. Scott, Valgerdur Steinthorsdottir, Andrew P. Morris, Christian Dina, et al.
  (2010) Nature Genetics
  Journal article
2009
- A variant in the KCNQ1 gene predicts future type 2 diabetes and mediates impaired insulin secretion.
  Anna Jonsson, Bo Isomaa, Tiinamaija Tuomi, Jalal Taneera, S Albert Salehi, et al.
  (2009) Diabetes
  Journal article
- Assessing the effect of interaction between an FTO variant (rs9939609) and physical activity on obesity in 15,925 Swedish and 2,511 Finnish adults.
  A Jonsson, F Renström, Valeriya Lyssenko, E Brito, B Isomaa, et al.
  (2009) Diabetologia
  Journal article
- Disruption of TFB1M impairs insulin secretion in beta cells
  Thomas Köck, Marloes Dekker Nitert, A Olsson, Olga Kotova, Jelena Stamenkovic, et al.
  (2009) Diabetologia
  Conference paper: abstract
- Fasting Versus Postload Plasma Glucose Concentration and the Risk for Future Type 2 Diabetes Results from the Botnia Study
  Muhammad A. Abdul-Ghani, Valeriya Lyssenko, Tiinamaija Tuomi, Ralph A. DeFronzo, Leif Groop
  (2009) Diabetes Care
  Journal article
- Functional Variant Disrupts Insulin Induction of USF1 Mechanism for USF1-Associated Dyslipidemias
  Jussi Naukkarinen, Emma Nilsson, Heikki A. Koistinen, Sanni Soderlund, Valeriya Lyssenko, et al.
  (2009) Circulation: Cardiovascular Genetics
  Journal article
- Genetic basis of beta-cell dysfunction in man.
  Leif Groop, Valeriya Lyssenko
  (2009) Diabetes, Obesity and Metabolism
  Journal article
- Genetics of type 2 diabetes. On overview.
  Leif Groop, Valeriya Lyssenko
  (2009) Endocrinologia y Nutricion
  Journal article
- Genome-wide association study for type 2 diabetes: clinical applications.
  Valeriya Lyssenko, Leif Groop
  (2009) Current Opinion in Lipidology
  Journal article
- Genome-wide meta-analysis identifies novel genetic loci associated with OGTT-induced post-challenge glucose
  C. Langenberg, R. Saxena, M. -F. Hivert, T. Tanaka, J. S. Pankow, et al.
  (2009) Diabetologia
  Conference paper: abstract
- Hyperactivity in adrenergic signalling via alpha2A receptors contributes to human type 2 diabetes
  Anders Rosengren, Ramunas Jokubka, Damon Tojjar, Charlotte Granhall, Jonatan Tuncel, et al.
  (2009) Diabetologia
  Conference paper: abstract
- Interaction between prenatal growth and high-risk genotypes in the development of type 2 diabetes
  N. Pulizzi, Valeriya Lyssenko, Anna Jonsson, C. Osmond, M. Laakso, et al.
  (2009) Diabetologia
  Journal article
- Melatonin receptors in pancreatic islets: good morning to a novel type 2 diabetes gene.
  Hindrik Mulder, Cecilia Nagorny, Valeriya Lyssenko, Leif Groop
  (2009) Diabetologia
  Journal article
- Prioritizing genes for follow-up from genome wide association studies using information on gene expression in tissues relevant for type 2 diabetes mellitus
  Hemang Parikh, Valeriya Lyssenko, Leif Groop
  (2009) BMC Medical Genomics
  Journal article
- The T allele of rs7903146 TCF7L2 is associated with impaired insulinotropic action of incretin hormones, reduced 24 h profiles of plasma insulin and glucagon, and increased hepatic glucose production in young healthy men
  K. Pilgaard, C. B. Jensen, J. H. Schou, Valeriya Lyssenko, L. Wegner, et al.
  (2009) Diabetologia
  Journal article
- The diabetes risk score outperforms fasting plasma glucose and glucose tolerance tests: combined results from the Inter99 and Botnia Studies
  M. P. McKenna, Valeriya Lyssenko, M. Rowe, R. Gerwien, J. Kolberg, et al.
  (2009) Diabetologia
  Conference paper: abstract
- Underlying Genetic Models of Inheritance in Established Type 2 Diabetes Associations
  Georgia Salanti, Lorraine Southam, David Altshuler, Kristin Ardlie, Ines Barroso, et al.
  (2009) American Journal of Epidemiology
  Journal article review
- Variants in MTNR1B influence fasting glucose levels
  Inga Prokopenko, Claudia Langenberg, Jose C. Florez, Richa Saxena, Nicole Soranzo, et al.
  (2009) Nature Genetics
  Journal article
2008
- Clinical risk factors, DNA variants, and the development of type 2 diabetes.
  Valeriya Lyssenko, Anna Jonsson, Peter Almgren, Nicolo Pulizzi, Bo Isomaa, et al.
  (2008) New England Journal of Medicine
  Journal article
- Common Missense Variant in the Glucokinase Regulatory Protein Gene Is Associated With Increased Plasma Triglyceride and C-Reactive Protein but Lower Fasting Glucose Concentrations
  Marju Orho-Melander, Olle Melander, Candace Guiducci, Pablo Perez-Martinez, Dolores Corella, et al.
  (2008) Diabetes
  Journal article
- Common variants in or around the JAZF1, CDKN2A/2B, CDKAL1 and WFS1 genes discriminate between autoimmune and non-autoimmune diabetes
  Ekaterine Bakhtadze, Eero Lindholm, Valeriya Lyssenko, H. J. Arnkvist, J. Bolinder, et al.
  (2008) Diabetologia
  Conference paper: abstract
- Genetic analysis of recently identified type 2 diabetes loci in 1,638 unselected patients with type 2 diabetes and 1,858 control participants from a Norwegian population-based cohort (the HUNT study)
  J K Hertel, S Johansson, H Raeder, K Midthjell, Valeriya Lyssenko, et al.
  (2008) Diabetologia
  Journal article
- Genetic similarities between latent autoimmune diabetes in adults, type 1 diabetes, and type 2 diabetes
  Camilla Cervin, Valeriya Lyssenko, Ekaterine Bakhtadze, Eero Lindholm, Peter Nilsson, et al.
  (2008) Diabetes
  Journal article
- Identification of ten loci associated with height highlights new biological pathways in human growth
  Guillaume Lettre, Anne U. Jackson, Christian Gieger, Fredrick R. Schumacher, Sonja I. Berndt, et al.
  (2008) Nature Genetics
  Journal article
- Interactions between genes and birth size for development of type 2 diabetes
  Nicolo Pulizzi, Valeriya Lyssenko, Anna Jonsson, C. Osmond, E. Kajantie, et al.
  (2008) Diabetologia
  Conference paper: abstract
- Is there a unifying genetic factor predisposing to the metabolic syndrome?
  Marketa Sjögren, Marju Orho-Melander, Anna Jonsson, Margareta Svensson, Göran Berglund, et al.
  (2008) Diabetologia
  Conference paper: abstract
- Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes
  Eleftheria Zeggini, Laura J. Scott, Richa Saxena, Benjamin F. Voight, Jonathan L. Marchini, et al.
  (2008) Nature Genetics
  Journal article
- Metabolic effects of novel type 2 diabetes genes in a population aged 18-75 years
  Anna Jonsson, B. Isomaa, Tiinamaija Tuomi, Valeriya Lyssenko, Leif Groop
  (2008) Diabetologia
  Conference paper: abstract
- The Pro12Ala polymorphism of the PPAR-gamma2 gene affects associations of fish intake and marine n-3 fatty acids with glucose metabolism
  SK Ylonen, I Salminen, Valeriya Lyssenko, SM Virtanen, Leif Groop, et al.
  (2008) European Journal of Clinical Nutrition
  Journal article
- The search for putative unifying genetic factors for components of the metabolic syndrome.
  Marketa Sjögren, Valeriya Lyssenko, Anna Jonsson, Göran Berglund, Peter Nilsson, et al.
  (2008) Diabetologia
  Journal article
- The transcription factor 7-like 2 gene and increased risk of type 2 diabetes: an update.
  Valeriya Lyssenko
  (2008) Current Opinion in Clinical Nutrition and Metabolic Care
  Journal article
- Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus
  Kazuki Yasuda, Kazuaki Miyake, Yukio Horikawa, Kazuo Hara, Haruhiko Osawa, et al.
  (2008) Nature Genetics
  Journal article
- Variations in the G6PC2/ABCB11 genomic region are associated with fasting glucose levels.
  Wei-Min Chen, Michael R Erdos, Anne U Jackson, Richa Saxena, Serena Sanna, et al.
  (2008) Journal of Clinical Investigation
  Journal article
2007
- Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels
  Richa Saxena, Benjamin F. Voight, Valeriya Lyssenko, Noel P. Burtt, Paul I. W. de Bakker, et al.
  (2007) Science
  Journal article
- Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes.
  Valeriya Lyssenko, Roberto Lupi, Piero Marchetti, Silvia Del Guerra, Marju Orho-Melander, et al.
  (2007) Journal of Clinical Investigation
  Journal article
- Polymorphisms in the gene encoding the voltage-dependent Ca(2+) channel Ca (V)2.3 (CACNA1E) are associated with type 2 diabetes and impaired insulin secretion
  Johan Holmkvist, Damon Tojjar, Peter Almgren, Valeriya Lyssenko, C M Lindgren, et al.
  (2007) Diabetologia
  Journal article
- Variants in the FFAR1 Gene Are Associated with Beta Cell Function
  Martins Kalis, Per Levéen, Valeriya Lyssenko, Peter Almgren, Leif Groop, et al.
  (2007) PLoS ONE
  Journal article
2006
- Analysis of the interleukin-1 and interleukin-6 polymorphisms in patients with chronic periodontitis. A pilot study
  H Jansson, Valeriya Lyssenko, A Gustavsson, K Hamberg, B Soderfeldt, et al.
  (2006) Swedish Dental Journal
  Journal article
- Authors' reply.
  Valeriya Lyssenko, Dragi Anevski, Peter Almgren, Leif Groop
  (2006) PLoS Medicine
  Journal article (letter)
- Common single nucleotide polymorphisms in TCF7L2 are reproducibly associated with type 2 diabetes and reduce the insulin response to glucose in nondiabetic individuals
  Richa Saxena, Lauren Gianniny, Noel P. Burtt, Valeriya Lyssenko, Candace Giuducci, et al.
  (2006) Diabetes
  Journal article
- Common variants in HNF-1 alpha and risk of type 2 diabetes.
  Johan Holmkvist, C Cervin, Valeriya Lyssenko, W Winckler, Dragi Anevski, et al.
  (2006) Diabetologia
  Journal article
- IL6 gene promoter polymorphisms and type 2 diabetes - Joint analysis of individual participants' data from 21 studies
  Cornelia Huth, Iris M. Heid, Caren Vollmert, Christian Gieger, Harald Grallert, et al.
  (2006) Diabetes
  Journal article
2005
- Genetic prediction of future type 2 diabetes
  Valeriya Lyssenko, Peter Almgren, Dragi Anevski, Marju Orho-Melander, Marketa Sjögren, et al.
  (2005) PLoS Medicine
  Journal article

Publications

Retrieved from Lund University's publications database

Book chapter
- From association to function : MTNR1B
  Amélie Bonnefond, Valeriya Lyssenko
  (2016) The Genetics of Type 2 Diabetes and Related Traits: Biology, Physiology and Translation, p.403-421
Conference paper
- Detailed Physiologic Characterization Reveals Diverse Mechanisms for Novel Genetic Loci Regulating Glucose and Insulin Metabolism in Humans
  Erik Ingelsson, Claudia Langenberg, Marie-France Hivert, Inga Prokopenko, Valeriya Lyssenko, et al.
  (2010) Diabetes, 59 p.1266-1275
Conference paper: abstract
- A meta-analysis of GWA blood glucose after 2 h of OGTT revealed that GIPR is associated with the secretion of insulin based on glucose and ADCY5 is a new susceptibility gene for type 2 diabetes.
  N. Bouatia-Naji, R. Saxena, M. F. Hivert, C. Langenberg, T. Tanaka, et al.
  (2010) Diabetes & Metabolism, 36 p.3-3
- Effect of variants in the RORA gene on risk of type 2 diabetes
  Anna Jonsson, Sami Alkayyali, B. Isomaa, T. Tuomi, Leif Groop, et al.
  (2010) Diabetologia, 53 p.304-304
- Polymorphisms in CACNA1D affect insulin release and channel expression and associate with type 2 diabetes
  Thomas Reinbothe, Valeriya Lyssenko, Stefan Lang, Erik Renström
  (2010) Diabetologia, 53 p.296-296
- A common variant in the PAX6 gene influences islet function in man
  Emma Ahlqvist, Fabiola Turrini, Stefan Lang, Targ Elgzyri, Yuedan Zhou, et al.
  (2010) Diabetologia, 53 p.297-297
- Influence of novel genetic loci affecting glucose and insulin levels during OGTT on islet function in man
  Tarun Ahluwalia, Claes Ladenvall, Anna Jonsson, Jasmina Kravic, Esa Laurila, et al.
  (2010) Diabetologia, 53 p.136-136
- Genetic susceptibility for obesity increases the risk of type 2 diabetes and is modified by macronutrient intakes
  Gull Rukh, Emily Sonestedt, Valeriya Lyssenko, Amitabh Sharma, Olle Melander, et al.
  (2010) Diabetologia, 53 p.50-50
- Genome wide association analysis for free fatty acid levels in DGI
  Ivana Stojkovic, C. Saloranta, Peter Almgren, Valeriya Lyssenko, E. Laurila, et al.
  (2010) Diabetologia, 53 p.322-322
- The diabetes risk score outperforms fasting plasma glucose and glucose tolerance tests: combined results from the Inter99 and Botnia Studies
  M. P. McKenna, Valeriya Lyssenko, M. Rowe, R. Gerwien, J. Kolberg, et al.
  (2009) Diabetologia, 52 p.7-7
- Hyperactivity in adrenergic signalling via alpha2A receptors contributes to human type 2 diabetes
  Anders Rosengren, Ramunas Jokubka, Damon Tojjar, Charlotte Granhall, Jonatan Tuncel, et al.
  (2009) Diabetologia, 52 p.108-108
- Disruption of TFB1M impairs insulin secretion in beta cells
  Thomas Köck, Marloes Dekker Nitert, A Olsson, Olga Kotova, Jelena Stamenkovic, et al.
  (2009) Diabetologia, 52 p.116-116
- Genome-wide meta-analysis identifies novel genetic loci associated with OGTT-induced post-challenge glucose
  C. Langenberg, R. Saxena, M. -F. Hivert, T. Tanaka, J. S. Pankow, et al.
  (2009) Diabetologia, 52 p.75-75
- Common variants in or around the JAZF1, CDKN2A/2B, CDKAL1 and WFS1 genes discriminate between autoimmune and non-autoimmune diabetes
  Ekaterine Bakhtadze, Eero Lindholm, Valeriya Lyssenko, H. J. Arnkvist, J. Bolinder, et al.
  (2008) Diabetologia, 51 p.117-117
- Is there a unifying genetic factor predisposing to the metabolic syndrome?
  Marketa Sjögren, Marju Orho-Melander, Anna Jonsson, Margareta Svensson, Göran Berglund, et al.
  (2008) Diabetologia, 51 p.32-33
- Metabolic effects of novel type 2 diabetes genes in a population aged 18-75 years
  Anna Jonsson, B. Isomaa, Tiinamaija Tuomi, Valeriya Lyssenko, Leif Groop
  (2008) Diabetologia, 51 p.31-32
- Interactions between genes and birth size for development of type 2 diabetes
  Nicolo Pulizzi, Valeriya Lyssenko, Anna Jonsson, C. Osmond, E. Kajantie, et al.
  (2008) Diabetologia, 51 p.28-28
Journal article
- A diabetes-associated genetic variant is associated with diastolic dysfunction and cardiovascular disease
  John Molvin, Amra Jujic, Peter M Nilsson, Margret Leosdottir, Ulf Lindblad, et al.
  (2019) ESC Heart Failure
- Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls
  Jason Flannick, Valeriya Lyssenko, Leif Groop, Peter Nilsson, Michael Boehnke
  (2019) Nature, 570 p.71-76
- Multiethnic Genome-Wide Association Study of Diabetic Retinopathy Using Liability Threshold Modeling of Duration of Diabetes and Glycemic Control
  Samuela Pollack, Leif Groop, Emma Ahlqvist, Valeriya Lyssenko, Elisabet Agardh, et al.
  (2019) Diabetes, 68 p.441-456
- Characteristics and prognosis of healthy severe obesity (HSO) subjects - The Malmo Preventive Project
  Maximilian Tremmel, Valeriya Lyssenko, Bengt Zöller, Gunnar Engström, Martin Magnusson, et al.
  (2018) Obesity Medicine, 11 p.6-12
- A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes
  Natalie R van Zuydam, Emma Ahlqvist, Claes Ladenvall, Peter Almgren, Christina-Alexandra Schulz, et al.
  (2018) Diabetes, 67 p.1414-1427
- A genome-wide association study suggests new evidence for an association of the NADPH Oxidase 4 (NOX4) gene with severe diabetic retinopathy in type 2 diabetes
  Weihua Meng, Kaanan P. Shah, Samuela Pollack, Iiro Toppila, Harry L. Hebert, et al.
  (2018) Acta Ophthalmologica, 96 p.811-819
- Sense of Coherence is associated with LDL-cholesterol in patients with type 1 diabetes – The PROLONG-Steno study
  Kasper Olesen, Troels Mygind Jensen, Lars Jorge Diaz, Anne Cathrine Laustrup Møller, Ingrid Willaing, et al.
  (2017) Journal of Clinical and Translational Endocrinology, 8 p.1-5
- Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis
  Eleanor Wheeler, Aaron Leong, Ching-Ti Liu, Marie-France Hivert, Rona J. Strawbridge, et al.
  (2017) PLoS Medicine, 14
- An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans
  Robert A. Scott, Laura J Scott, Reedik Mägi, Letizia Marullo, Kyle J Gaulton, et al.
  (2017) Diabetes, 66 p.2888-2902
- Data Descriptor: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls
  Jason Flannick, Christian Fuchsberger, Anubha Mahajan, Tanya M Teslovich, Vineeta Agarwala, et al.
  (2017) Scientific Data, 4
- A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape
  Janina S. Ried, Janina M. Jeff, Audrey Y. Chu, Jennifer L. Bragg-Gresham, Jenny Van Dongen, et al.
  (2016) Nature Communications, 7
- Impact of the tcf7l2 genotype on risk of hypoglycaemia and glucagon secretion during hypoglycaemia
  Peter L. Kristensen, Ulrik Pedersen-Bjergaard, Rikke Due-Andersen, Thomas Høi-Hansen, Lise Grimmeshave, et al.
  (2016) Endocrine Connections, 5 p.53-60
- Personalized therapy by phenotype and genotype
  Valeriya Lyssenko, Cristina Bianchi, Stefano Del Prato
  (2016) Diabetes Care, 39 p.127-136
- CART is overexpressed in human type 2 diabetic islets and inhibits glucagon secretion and increases insulin secretion
  Mia Abels, Matteo Riva, Hedvig Bennet, Emma Ahlqvist, Oleg Dyachok, et al.
  (2016) Diabetologia, 59 p.1928-1937
- Glucose-dependent insulinotropic polypeptide (GIP) and GIP receptor (GIPR) genes : An association analysis of polymorphisms and bone in young and elderly women
  Gaurav Garg, Fiona E. McGuigan, Jitender Kumar, Holger Luthman, Valeriya Lyssenko, et al.
  (2016) Bone Reports, 4 p.23-27
- Atrial Natriuretic Peptide in the high normal range is associated with lower prevalence of insulin resistance.
  Amra Jujic, Peter Nilsson, Margaretha Persson, Jens Juul Holst, Signe Sørensen Torekov, et al.
  (2016) The Journal of clinical endocrinology and metabolism, 101 p.1372-1380
- Genetic predisposition for beta cell fragility underlies type 1 and type 2 diabetes
  James Dooley, Lei Tian, Susann Schonefeldt, Viviane Delghingaro-Augusto, Josselyn E Garcia-Perez, et al.
  (2016) Nature Genetics, 48 p.519-527
- A Variant of GJD2, Encoding for Connexin 36, Alters the Function of Insulin Producing β-Cells.
  Valentina Cigliola, Celine Populaire, Ciro L Pierri, Samuel Deutsch, Jacques-Antoine Haefliger, et al.
  (2016) PLoS ONE, 11
- Glucose-Dependent Insulinotropic Polypeptide (GIP) Stimulates Osteopontin Expression in the Vasculature via Endothelin-1 and CREB.
  Lisa Berglund, Valeriya Lyssenko, Claes Ladenvall, Olga Kotova, Andreas Edsfeldt, et al.
  (2016) Diabetes, 65 p.239-254
- The genetic architecture of type 2 diabetes
  Christian Fuchsberger, Tibor V. Varga, Claes Ladenvall, Jasmina Kravic, Paul Franks, et al.
  (2016) Nature, 536 p.41-47
- Variation in Glucose Homeostasis Traits Associated With P2RX7 Polymorphisms in Mice and Humans
  Jennifer N. Todd, Wenny Poon, Valeriya Lyssenko, Leif Groop, Brendan Nichols, et al.
  (2015) Journal of Clinical Endocrinology and Metabolism, 100 p.688-696
- Using genetic variants to assess the relationship between circulating lipids and type 2 diabetes.
  Tove Fall, Weijia Xie, Wenny Poon, Hanieh Yaghootkar, Reedik Mägi, et al.
  (2015) Diabetes, 64 p.2676-2684
- Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation.
  Momoko Horikoshi, Reedik Mӓgi, Martijn van de Bunt, Ida Surakka, Antti-Pekka Sarin, et al.
  (2015) PLoS Genetics, 11
- New genetic loci link adipose and insulin biology to body fat distribution.
  Dmitry Shungin, Thomas W Winkler, Damien C Croteau-Chonka, Teresa Ferreira, Adam E Locke, et al.
  (2015) Nature, 518 p.187-378
- Genetic studies of body mass index yield new insights for obesity biology.
  Adam E Locke, Bratati Kahali, Sonja I Berndt, Anne E Justice, Tune H Pers, et al.
  (2015) Nature, 518 p.197-401
- The impact of low-frequency and rare variants on lipid levels.
  Ida Surakka, Momoko Horikoshi, Reedik Mägi, Antti-Pekka Sarin, Anubha Mahajan, et al.
  (2015) Nature Genetics, 47 p.589-597
- The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.
  Thomas W Winkler, Anne E Justice, Mariaelisa Graff, Llilda Barata, Mary F Feitosa, et al.
  (2015) PLoS Genetics, 11
- Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci.
  Kyle J Gaulton, Teresa Ferreira, Yeji Lee, Anne Raimondo, Reedik Mägi, et al.
  (2015) Nature Genetics, 47 p.1415-1415
- Age- and Sex-Specific Causal Effects of Adiposity on Cardiovascular Risk Factors.
  Tove Fall, Sara Hägg, Alexander Ploner, Reedik Mägi, Krista Fischer, et al.
  (2015) Diabetes, 64 p.1841-1852
- Modelling of OGTT curve identifies 1 h plasma glucose level as a strong predictor of incident type 2 diabetes: results from two prospective cohorts
  Akram Alyass, Peter Almgren, Mikael Åkerlund, Jonathan Dushoff, Bo Isomaa, et al.
  (2015) Diabetologia, 58 p.87-97
- Genetics of diabetes complications.
  Sami Alkayyali, Valeriya Lyssenko
  (2014) Mammalian Genome, 25 p.384-400
- Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility
  Anubha Mahajan, Min Jin Go, Weihua Zhang, Jennifer E. Below, Kyle J. Gaulton, et al.
  (2014) Nature Genetics, 46 p.234-234
- A Central Role for GRB10 in Regulation of Islet Function in Man.
  Inga Prokopenko, Wenny Poon, Reedik Mägi, Rashmi Prasad, S Albert Salehi, et al.
  (2014) PLoS Genetics, 10
- Genetic Variants Associated With Glycine Metabolism and Their Role in Insulin Sensitivity and Type 2 Diabetes
  Weijia Xie, Andrew R. Wood, Valeriya Lyssenko, Michael N. Weedon, Joshua W. Knowles, et al.
  (2013) Diabetes, 62 p.2141-2150
- Genetic Screening for the Risk of Type 2 Diabetes. Worthless or valuable?
  Valeriya Lyssenko, Markku Laakso
  (2013) Diabetes Care, 36 p.120-126
- Assessing the phenotypic effects in the general population of rare variants in genes for a dominant Mendelian form of diabetes
  Jason Flannick, Nicola L. Beer, Alexander G. Bick, Vineeta Agarwala, Janne Molnes, et al.
  (2013) Nature Genetics, 45 p.1380-1380
- Early Metabolic Markers of the Development of Dysglycemia and Type 2 Diabetes and Their Physiological Significance
  Ele Ferrannini, Andrea Natali, Stefania Camastra, Monica Nannipieri, Andrea Mari, et al.
  (2013) Diabetes, 62 p.1730-1737
- Effect of Common Genetic Variants Associated with Type 2 Diabetes and Glycemic Traits on α- and β-cell Function and Insulin Action in Man.
  Anna Jonsson, Claes Ladenvall, Tarunveer Singh Ahluwalia, Jasmina Kravic, Ulrika Krus, et al.
  (2013) Diabetes, 62 p.2978-2983
- A link between GIP and osteopontin in adipose tissue and insulin resistance.
  Emma Ahlqvist, Peter Osmark, Tiina Kuulasmaa, Kasper Pilgaard, Bilal Omar, et al.
  (2013) Diabetes, 62 p.2088-2094
- The human L-type calcium channel Ca(v)1.3 regulates insulin release and polymorphisms in CACNA1D associate with type 2 diabetes.
  Thomas Reinbothe, Sami Alkayyali, Emma Ahlqvist, Tiinamaija Tuomi, Bo Isomaa, et al.
  (2013) Diabetologia, 56 p.340-349
- The Role of Adiposity in Cardiometabolic Traits: A Mendelian Randomization Analysis
  Tove Fall, Sara Hagg, Reedik Maegi, Alexander Ploner, Krista Fischer, et al.
  (2013) PLoS Medicine, 10
- Common variant in the HMGA2 gene increases susceptibility to nephropathy in patients with type 2 diabetes.
  Sami Alkayyali, M Lajer, H Deshmukh, Emma Ahlqvist, H Colhoun, et al.
  (2012) Diabetologia
- Effect of a common variant of the PCSK2 gene on reduced insulin secretion.
  Anna Jonsson, B Isomaa, Tiinamaija Tuomi, Jonas Eriksson, Leif Groop, et al.
  (2012) Diabetologia
- A systems genetics approach identifies genes and pathways for type 2 diabetes in human islets.
  Jalal Taneera, Stefan Lang, Amitabh Sharma, Joao Fadista, Yuedan Zhou, et al.
  (2012) Cell Metabolism, 16 p.122-134
- A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance
  Alisa K. Manning, Marie-France Hivert, Robert A. Scott, Jonna L. Grimsby, Nabila Bouatia-Naji, et al.
  (2012) Nature Genetics, 44 p.81-659
- Reduced Insulin Exocytosis in Human Pancreatic β-cells With Gene Variants Linked to Type 2 Diabetes.
  Anders Rosengren, Matthias Braun, Taman Mahdi, Sofia A Andersson, Mary E Travers, et al.
  (2012) Diabetes, 61 p.1726-1733
- Tired of Diabetes Genetics? Circadian Rhythms and Diabetes: The MTNR1B Story?
  Cecilia Nagorny, Valeriya Lyssenko
  (2012) Current Diabetes Reports, 12 p.667-672
- Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
  Andrew P. Morris, Benjamin F. Voight, Tanya M. Teslovich, Teresa Ferreira, Ayellet V. Segre, et al.
  (2012) Nature Genetics, 44 p.981-981
- Codon 72 polymorphism (rs1042522) of TP53 is associated with changes in diastolic blood pressure over time
  Erwin Reiling, Valeriya Lyssenko, Jolanda M. A. Boer, Sandra Imholz, W. Monique M. Verschuren, et al.
  (2012) European Journal of Human Genetics, 20 p.696-700
- Genetic prediction of postpartum diabetes in women with gestational diabetes mellitus
  Magnus Ekelund, Nael Shaat, Peter Almgren, Eva Anderberg, Mona Landin-Olsson, et al.
  (2012) Diabetes Research and Clinical Practice, 97 p.394-398
- Genetic Variation in the Glucose-Dependent Insulinotropic Polypeptide Receptor Modifies the Association between Carbohydrate and Fat Intake and Risk of Type 2 Diabetes in the Malmo Diet and Cancer Cohort.
  Emily Sonestedt, Valeriya Lyssenko, Ulrika Ericson, Bo Gullberg, Elisabet Wirfält, et al.
  (2012) The Journal of clinical endocrinology and metabolism, 97 p.810-818
- Kartläggning av skyddsfaktorer vid typ 1-diabetes har börjat. Vissa patienter tycks skyddade mot sena komplikationer--flera studier pågår.
  Valeriya Lyssenko, Peter Nilsson
  (2012) Läkartidningen, 109 p.744-745
- Regulation of the pro-inflammatory cytokine osteopontin by GIP in adipocytes - A role for the transcription factor NFAT and phosphodiesterase 3B.
  Bilal Omar, Elin Banke, Emilia Guiguis, Lina Kesson, Vincent Manganiello, et al.
  (2012) Biochemical and Biophysical Research Communications, 425 p.812-817
- Validation of a multi-marker model for the prediction of incident type 2 diabetes mellitus: Combined results of the Inter99 and Botnia studies.
  Valeriya Lyssenko, Torben Jørgensen, Robert W Gerwien, Torben Hansen, Michael W Rowe, et al.
  (2012) Diabetes & Vascular Disease Research, 9 p.59-67
- No Interactions Between Previously Associated 2-Hour Glucose Gene Variants and Physical Activity or BMI on 2-Hour Glucose Levels
  Robert A. Scott, Audrey Y. Chu, Niels Grarup, Alisa K. Manning, Marie-France Hivert, et al.
  (2012) Diabetes, 61 p.1291-1296
- Secreted frizzled-related protein 4 reduces insulin secretion and is overexpressed in type 2 diabetes.
  Taman Mahdi, Sonja Hänzelmann, S Albert Salehi, Sarheed Jabar Muhammed, Thomas Reinbothe, et al.
  (2012) Cell Metabolism, 16 p.625-633
- A common variant upstream of the PAX6 gene influences islet function in man.
  Emma Ahlqvist, Fabiola Turrini, Stefan Lang, Jalal Taneera, Yuedan Zhou, et al.
  (2012) Diabetologia, 55 p.94-104
- Heritability and familiality of type 2 diabetes and related quantitative traits in the Botnia Study.
  Peter Almgren, M Lehtovirta, B Isomaa, L Sarelin, M R Taskinen, et al.
  (2011) Diabetologia, 54 p.2811-2819
- A common variant in TFB1M is associated with reduced insulin secretion and increased future risk of type 2 diabetes.
  Thomas Koeck, Anders H Olsson, Marloes Dekker Nitert, Vladimir Sharoyko, Claes Ladenvall, et al.
  (2011) Cell Metabolism, 13 p.80-91
- Pleiotropic Effects of GIP on Islet Function Involve Osteopontin
  Valeriya Lyssenko, Lena Eliasson, Olga Kotova, Kasper Pilgaard, Nils Wierup, et al.
  (2011) Diabetes, 60 p.2424-2433
- Association between parental history of diabetes and type 2 diabetes genetic risk scores in the PPP-Botnia and Framingham Offspring Studies
  Jason L. Vassy, Peter Shrader, Anna Jonsson, Caroline S. Fox, Valeriya Lyssenko, et al.
  (2011) Diabetes Research and Clinical Practice, 93 p.76-79
- Power in the Phenotypic Extremes: A Simulation Study of Power in Discovery and Replication of Rare Variants
  Lin T. Guey, Jasmina Kravic, Olle Melander, Noel P. Burtt, Jason M. Laramie, et al.
  (2011) Genetic Epidemiology, 35 p.236-246
- Genome-Wide Association Identifies Nine Common Variants Associated With Fasting Proinsulin Levels and Provides New Insights Into the Pathophysiology of Type 2 Diabetes
  Rona J. Strawbridge, Josee Dupuis, Inga Prokopenko, Adam Barker, Emma Ahlqvist, et al.
  (2011) Diabetes, 60 p.2624-2634
- FTO, Type 2 Diabetes, and Weight Gain Throughout Adult Life A Meta-Analysis of 41,504 Subjects From the Scandinavian HUNT, MDC, and MPP Studies
  Jens K. Hertel, Stefan Johansson, Emily Sonestedt, Anna Jonsson, Rolv T. Lie, et al.
  (2011) Diabetes, 60 p.1637-1644
- Minimal Contribution of Fasting Hyperglycemia to the Incidence of Type 2 Diabetes in Subjects With Normal 2-h Plasma Glucose
  Muhammad A. Abdul-Ghani, Michael P. Stern, Valeriya Lyssenko, Tiinamaija Tuomi, Leif Groop, et al.
  (2010) Diabetes Care, 33 p.557-561
- A family history of diabetes is associated with reduced physical fitness in the Prevalence, Prediction and Prevention of Diabetes (PPP)-Botnia study
  B. Isomaa, B. Forsen, K. Lahti, N. Holmstrom, J. Waden, et al.
  (2010) Diabetologia, 53 p.1709-1713
- The shape of plasma glucose concentration curve during OGTT predicts future risk of type 2 diabetes
  Muhammad A. Abdul-Ghani, Valeriya Lyssenko, Tiinamaija Tuomi, Ralph A. DeFronzo, Leif Groop
  (2010) Diabetes/Metabolism Research Reviews, 26 p.280-286
- Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge
  Richa Saxena, Marie-France Hivert, Claudia Langenberg, Toshiko Tanaka, James S. Pankow, et al.
  (2010) Nature Genetics, 42 p.75-142
- GAD Antibody Positivity Predicts Type 2 Diabetes in an Adult Population
  Virve M. Lundgren, Bo Isomaa, Valeriya Lyssenko, Esa Laurila, Pasi Korhonen, et al.
  (2010) Diabetes, 59 p.416-422
- New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
  Josee Dupuis, Claudia Langenberg, Inga Prokopenko, Richa Saxena, Nicole Soranzo, et al.
  (2010) Nature Genetics, 42 p.32-105
- Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis
  Benjamin F. Voight, Laura J. Scott, Valgerdur Steinthorsdottir, Andrew P. Morris, Christian Dina, et al.
  (2010) Nature Genetics, 42 p.155-579
- Genetic basis of beta-cell dysfunction in man.
  Leif Groop, Valeriya Lyssenko
  (2009) Diabetes, Obesity and Metabolism, 11 Suppl 4 p.149-158
- Genome-wide association study for type 2 diabetes: clinical applications.
  Valeriya Lyssenko, Leif Groop
  (2009) Current Opinion in Lipidology, 20 p.87-91
- Melatonin receptors in pancreatic islets: good morning to a novel type 2 diabetes gene.
  Hindrik Mulder, Cecilia Nagorny, Valeriya Lyssenko, Leif Groop
  (2009) Diabetologia, 52 p.1240-1249
- Fasting Versus Postload Plasma Glucose Concentration and the Risk for Future Type 2 Diabetes Results from the Botnia Study
  Muhammad A. Abdul-Ghani, Valeriya Lyssenko, Tiinamaija Tuomi, Ralph A. DeFronzo, Leif Groop
  (2009) Diabetes Care, 32 p.281-286
- Variants in MTNR1B influence fasting glucose levels
  Inga Prokopenko, Claudia Langenberg, Jose C. Florez, Richa Saxena, Nicole Soranzo, et al.
  (2009) Nature Genetics, 41 p.77-81
- Genetics of type 2 diabetes. On overview.
  Leif Groop, Valeriya Lyssenko
  (2009) Endocrinologia y Nutricion, 56 Suppl 4 p.34-37
- Prioritizing genes for follow-up from genome wide association studies using information on gene expression in tissues relevant for type 2 diabetes mellitus
  Hemang Parikh, Valeriya Lyssenko, Leif Groop
  (2009) BMC Medical Genomics, 2
- The T allele of rs7903146 TCF7L2 is associated with impaired insulinotropic action of incretin hormones, reduced 24 h profiles of plasma insulin and glucagon, and increased hepatic glucose production in young healthy men
  K. Pilgaard, C. B. Jensen, J. H. Schou, Valeriya Lyssenko, L. Wegner, et al.
  (2009) Diabetologia, 52 p.1298-1307
- A variant in the KCNQ1 gene predicts future type 2 diabetes and mediates impaired insulin secretion.
  Anna Jonsson, Bo Isomaa, Tiinamaija Tuomi, Jalal Taneera, S Albert Salehi, et al.
  (2009) Diabetes, 58 p.2409-2413
- Assessing the effect of interaction between an FTO variant (rs9939609) and physical activity on obesity in 15,925 Swedish and 2,511 Finnish adults.
  A Jonsson, F Renström, Valeriya Lyssenko, E Brito, B Isomaa, et al.
  (2009) Diabetologia, 52 p.1334-1338
- Interaction between prenatal growth and high-risk genotypes in the development of type 2 diabetes
  N. Pulizzi, Valeriya Lyssenko, Anna Jonsson, C. Osmond, M. Laakso, et al.
  (2009) Diabetologia, 52 p.825-829
- Functional Variant Disrupts Insulin Induction of USF1 Mechanism for USF1-Associated Dyslipidemias
  Jussi Naukkarinen, Emma Nilsson, Heikki A. Koistinen, Sanni Soderlund, Valeriya Lyssenko, et al.
  (2009) Circulation: Cardiovascular Genetics, 2 p.245-522
- Genetic analysis of recently identified type 2 diabetes loci in 1,638 unselected patients with type 2 diabetes and 1,858 control participants from a Norwegian population-based cohort (the HUNT study)
  J K Hertel, S Johansson, H Raeder, K Midthjell, Valeriya Lyssenko, et al.
  (2008) Diabetologia, 51 p.971-977
- Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus
  Kazuki Yasuda, Kazuaki Miyake, Yukio Horikawa, Kazuo Hara, Haruhiko Osawa, et al.
  (2008) Nature Genetics, 40 p.1092-1097
- Variations in the G6PC2/ABCB11 genomic region are associated with fasting glucose levels.
  Wei-Min Chen, Michael R Erdos, Anne U Jackson, Richa Saxena, Serena Sanna, et al.
  (2008) Journal of Clinical Investigation, Jun 2 p.2620-2628
- Clinical risk factors, DNA variants, and the development of type 2 diabetes.
  Valeriya Lyssenko, Anna Jonsson, Peter Almgren, Nicolo Pulizzi, Bo Isomaa, et al.
  (2008) New England Journal of Medicine, 359 p.2220-2232
- The transcription factor 7-like 2 gene and increased risk of type 2 diabetes: an update.
  Valeriya Lyssenko
  (2008) Current Opinion in Clinical Nutrition and Metabolic Care, 11 p.385-392
- The search for putative unifying genetic factors for components of the metabolic syndrome.
  Marketa Sjögren, Valeriya Lyssenko, Anna Jonsson, Göran Berglund, Peter Nilsson, et al.
  (2008) Diabetologia, 51 p.2242-2251
- Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes
  Eleftheria Zeggini, Laura J. Scott, Richa Saxena, Benjamin F. Voight, Jonathan L. Marchini, et al.
  (2008) Nature Genetics, 40 p.638-645
- Genetic similarities between latent autoimmune diabetes in adults, type 1 diabetes, and type 2 diabetes
  Camilla Cervin, Valeriya Lyssenko, Ekaterine Bakhtadze, Eero Lindholm, Peter Nilsson, et al.
  (2008) Diabetes, 57 p.1433-1437
- Common Missense Variant in the Glucokinase Regulatory Protein Gene Is Associated With Increased Plasma Triglyceride and C-Reactive Protein but Lower Fasting Glucose Concentrations
  Marju Orho-Melander, Olle Melander, Candace Guiducci, Pablo Perez-Martinez, Dolores Corella, et al.
  (2008) Diabetes, 57 p.3112-3121
- Identification of ten loci associated with height highlights new biological pathways in human growth
  Guillaume Lettre, Anne U. Jackson, Christian Gieger, Fredrick R. Schumacher, Sonja I. Berndt, et al.
  (2008) Nature Genetics, 40 p.584-591
- The Pro12Ala polymorphism of the PPAR-gamma2 gene affects associations of fish intake and marine n-3 fatty acids with glucose metabolism
  SK Ylonen, I Salminen, Valeriya Lyssenko, SM Virtanen, Leif Groop, et al.
  (2008) European Journal of Clinical Nutrition, 62 p.1432-1439
- Variants in the FFAR1 Gene Are Associated with Beta Cell Function
  Martins Kalis, Per Levéen, Valeriya Lyssenko, Peter Almgren, Leif Groop, et al.
  (2007) PLoS ONE, 2
- Polymorphisms in the gene encoding the voltage-dependent Ca(2+) channel Ca (V)2.3 (CACNA1E) are associated with type 2 diabetes and impaired insulin secretion
  Johan Holmkvist, Damon Tojjar, Peter Almgren, Valeriya Lyssenko, C M Lindgren, et al.
  (2007) Diabetologia, 50 p.2467-2475
- Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes.
  Valeriya Lyssenko, Roberto Lupi, Piero Marchetti, Silvia Del Guerra, Marju Orho-Melander, et al.
  (2007) Journal of Clinical Investigation, 117 p.2155-2163
- Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels
  Richa Saxena, Benjamin F. Voight, Valeriya Lyssenko, Noel P. Burtt, Paul I. W. de Bakker, et al.
  (2007) Science, 316 p.1331-1336
- Analysis of the interleukin-1 and interleukin-6 polymorphisms in patients with chronic periodontitis. A pilot study
  H Jansson, Valeriya Lyssenko, A Gustavsson, K Hamberg, B Soderfeldt, et al.
  (2006) Swedish Dental Journal, 30 p.17-23
- Common single nucleotide polymorphisms in TCF7L2 are reproducibly associated with type 2 diabetes and reduce the insulin response to glucose in nondiabetic individuals
  Richa Saxena, Lauren Gianniny, Noel P. Burtt, Valeriya Lyssenko, Candace Giuducci, et al.
  (2006) Diabetes, 55 p.2890-2895
- IL6 gene promoter polymorphisms and type 2 diabetes - Joint analysis of individual participants' data from 21 studies
  Cornelia Huth, Iris M. Heid, Caren Vollmert, Christian Gieger, Harald Grallert, et al.
  (2006) Diabetes, 55 p.2915-2921
- Common variants in HNF-1 alpha and risk of type 2 diabetes.
  Johan Holmkvist, C Cervin, Valeriya Lyssenko, W Winckler, Dragi Anevski, et al.
  (2006) Diabetologia, 49 p.2882-2891
- Genetic prediction of future type 2 diabetes
  Valeriya Lyssenko, Peter Almgren, Dragi Anevski, Marju Orho-Melander, Marketa Sjögren, et al.
  (2005) PLoS Medicine, 2 p.1299-1308
Journal article (letter)
- Analysis of TBC1D4 in patients with severe insulin resistance
  S. Dash, C. Langenberg, K. A. Fawcett, R. K. Semple, S. Romeo, et al.
  (2010) Diabetologia, 53 p.1239-1242
- Authors' reply.
  Valeriya Lyssenko, Dragi Anevski, Peter Almgren, Leif Groop
  (2006) PLoS Medicine, 3 p.271-272
Journal article review
- Genetics of type 2 diabetes : It matters from which parent we inherit the risk
  Valeriya Lyssenko, Leif Groop, Rashmi B. Prasad
  (2015) Review of Diabetic Studies, 12 p.233-242
- Underlying Genetic Models of Inheritance in Established Type 2 Diabetes Associations
  Georgia Salanti, Lorraine Southam, David Altshuler, Kristin Ardlie, Ines Barroso, et al.
  (2009) American Journal of Epidemiology, 170 p.537-545

21 February 2017

Valeriya Lyssenko

E-mail: valeriya [dot] lyssenko [at] med [dot] lu [dot] se

Researcher

Genomics, Diabetes and Endocrinology

Telephone number:+46 40 39 12 44

Mobile number:+46 73 042 73 52

Room number:20:3:357

Visiting address:Wallenberg laboratoriet, plan. 3, Malmö,

Service point:33

Researcher

EXODIAB: Excellence in Diabetes Research in Sweden

Researcher

EpiHealth: Epidemiology for Health

My profile in Lund University research portal

Lund University Diabetes Centre

Excellence of diabetes research in Sweden

Valeriya Lyssenko

Publications

Publications

Publications