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Tina Rönn

Tina Rönn

Assistant researcher

Tina Rönn

Epigenetic adaptation to regular exercise in humans.

Author

  • Charlotte Ling
  • Tina Rönn

Summary, in English

Regular exercise has numerous health benefits, for example, it reduces the risk of cardiovascular disease and cancer. It has also been shown that the risk of type 2 diabetes can be halved in high-risk groups through nonpharmacological lifestyle interventions involving exercise and diet. Nevertheless, the number of people living a sedentary life is dramatically increasing worldwide. Researchers have searched for molecular mechanisms explaining the health benefits of regular exercise for decades and it is well established that exercise alters the gene expression pattern in multiple tissues. However, until recently it was unknown that regular exercise can modify the genome-wide DNA methylation pattern in humans. This review will focus on recent progress in the field of regular exercise and epigenetics.

Department/s

  • Diabetes - Epigenetics
  • EXODIAB: Excellence in Diabetes Research in Sweden

Publishing year

2014

Language

English

Pages

1015-1018

Publication/Series

Drug Discovery Today

Volume

19

Issue

7

Document type

Journal article review

Publisher

Elsevier

Topic

  • Pharmaceutical Sciences

Status

Published

Research group

  • Diabetes - Epigenetics

ISBN/ISSN/Other

  • ISSN: 1878-5832