Current position

Post-Doctoral Fellow

Research interests

Epigeneetics and genetics in type 2 diabetes and related metabolic diseases.
Personalized medicine in the progression and treatment of type 2 diabetes.

Ongoing projects

Finding blood epigenetic biomarkers to predict the risk of vascular complations and therapeutic response in patients with type 2 diabetes (ANDIS).
Analyzing genome-wide DNA methylation in whole blood using 850K Illumina DNA methylation array to identify epigenetic biomarkers, followed by technical and biological validation.
Perform functional follow-up studies to assess the key role of epigenetic biomarkers in the progression of type 2 diabetes.

Grants

Marie-Curie Individual Fellowship (Horizon 2020), 2016-2018.

Selected publication

García-Calzón S, Moleres A, Gómez-Martinez S, Diaz LE, Bueno G, Campoy C, Martinez JA, Marcos A, Azcona-Sanjulián MC, Zalba G, Marti A; EVASYON study group. Association of telomere length with IL-6 levels during an obesity treatment in adolescents: interaction with the-174G/C polymorphism in the IL-6gene. Pediatr Obes. 2016 Apr 13. doi: 10.1111/ijpo.12136, in press.

García-Calzón S, Zalba G, Ruiz-Canela M, Shivappa N, Hébert JR, Martínez JA, Fitó M, Gómez-Gracia E, Martínez-González MA, Marti A. Dietary inflammatory index and telomere length in subjects with a high cardiovascular disease risk from the PREDIMED-NAVARRA study: cross-sectional and longitudinal analyses over 5 y. Am J Clin Nutr. 2015;102:897-904.

García-Calzón S, Martínez-González MA, Razquin C, Corella D, Salas-Salvadó J, Martínez JA, Zalba G, Marti A. Pro12Ala polymorphism of the PPARγ2 gene interacts with a Mediterranean diet to prevent telomere shortening in the PREDIMED-NAVARRA randomized trial. Circ Cardiovasc Genet. 2015;8:91-9.

García-Calzón S, Gea A, Razquin C, Corella D, Lamuela-Raventós RM, Martínez JA, Martínez-González MA, Zalba G, Marti A. Longitudinal association of telomere length and obesity indices in an intervention study with a Mediterranean diet: the PREDIMED-NAVARRA trial. Int J Obes (Lond). 2014;38:177-82.