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Simon Timpka

Research team manager

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A prospective study of the relationships between movement and glycemic control during day and night in pregnancy

Author

  • Masoud Behravesh
  • Juan Fernandez-Tajes
  • Angela C. Estampador
  • Tibor V. Varga
  • Ómar S. Gunnarsson
  • Helena Strevens
  • Simon Timpka
  • Paul W. Franks

Summary, in English

Both disturbed sleep and lack of exercise can disrupt metabolism in pregnancy. Accelerometery was used to objectively assess movement during waking (physical activity) and movement during sleeping (sleep disturbance) periods and evaluated relationships with continuous blood glucose variation during pregnancy. Data was analysed prospectively. 15-women without pre-existing diabetes mellitus wore continuous glucose monitors and triaxial accelerometers from February through June 2018 in Sweden. The relationships between physical activity and sleep disturbance with blood glucose rate of change were assessed. An interaction term was fitted to determine difference in the relationship between movement and glucose variation, conditional on waking/sleeping. Total movement was inversely related to glucose rate of change (p < 0.001, 95% CI (− 0.037, − 0.026)). Stratified analyses showed total physical activity was inversely related to glucose rate of change (p < 0.001, 95% CI (− 0.040, − 0.028)), whereas sleep disturbance was not related to glucose rate of change (p = 0.07, 95% CI (< − 0.001, 0.013)). The interaction term was positively related to glucose rate of change (p < 0.001, 95% CI (0.029, 0.047)). This study provides temporal evidence of a relationship between total movement and glycemic control in pregnancy, which is conditional on time of day. Movement is beneficially related with glycemic control while awake, but not during sleep.

Department/s

  • Genetic and Molecular Epidemiology
  • EXODIAB: Excellence of Diabetes Research in Sweden
  • Perinatal and cardiovascular epidemiology
  • EpiHealth: Epidemiology for Health

Publishing year

2021

Language

English

Publication/Series

Scientific Reports

Volume

11

Issue

1

Document type

Journal article

Publisher

Nature Publishing Group

Topic

  • Endocrinology and Diabetes

Status

Published

Research group

  • Genetic and Molecular Epidemiology
  • Perinatal and cardiovascular epidemiology

ISBN/ISSN/Other

  • ISSN: 2045-2322