
Sebastian Kalamajski
Assistant researcher
Key interest
- Functional genomics
- Molecular biology
- Human genetics
Background
Sebastian has obtained his Ph.D. in cell- and molecular biology in 2008 at Lund University, in Prof. Åke Oldberg's lab. He pursued his research interests during postdoctoral fellowships in Uppsala University in Prof. Kristofer Rubin's lab, and at Harvard Medical School in Prof. Matthew Warman's lab. He then held researcher positions at Lund University and at Uppsala University, before joining Paul Franks' lab in 2018.
Publications
Displaying of publications. Sorted by year, then title.
Genomic editing of metformin efficacy-associated genetic variants in SLC47A1 does not alter SLC47A1 expression
Sebastian Kalamajski, Mi Huang, Jonathan Dalla-Riva, Maria Keller, Adem Y Dawed, et al.
(2022) Human Molecular Genetics, 31 p.491-498
Journal articleGenetic variation at RAB3GAP2 and its role in exercise-related adaptation and recovery
Kristoffer Ström, Nikolay Oskolkov, Tugce Karaderi, Sebastian Kalamajski, Ola Ekström, et al.
(2021) , p.1-16
PreprintCRISPR editing of the PPARGC1A Gly482ser (rs8192678) polymorphism in human white adipose cells shows differential effects on mitochondrial function and adipogenesis.
M. Huang, M. Claussnitzer, A. Saadat, Hindrik Mulder, Sebastian Kalamajski, et al.
(2021) Diabetologia, 64 p.159-159
Conference paper: abstractCathepsin g Degrades Both Glycosylated and Unglycosylated Regions of Lubricin, a Synovial Mucin
Shan Huang, Kristina A. Thomsson, Chunsheng Jin, Sally Alweddi, André Struglics, et al.
(2020) Scientific Reports, 10
Journal articleEpigenetic markers associated with metformin response and intolerance in drug-naïve patients with type 2 diabetes
Sonia García-Calzón, Alexander Perfilyev, Mats Martinell, Monta Ustinova, Sebastian Kalamajski, et al.
(2020) Science Translational Medicine, 12
Journal articleInhibition of integrin αvβ6 changes fibril thickness of stromal collagen in experimental carcinomas
P. Olof Olsson, Renata Gustafsson, Alexei V. Salnikov, Maria Göthe, Kathrin S. Zeller, et al.
(2018) Cell Communication and Signaling, 16
Journal articleLubricin binds cartilage proteins, cartilage oligomeric matrix protein, fibronectin and collagen II at the cartilage surface
Sarah A. Flowers, Agata Zieba, Jessica Örnros, Chunsheng Jin, Ola Rolfson, et al.
(2017) Scientific Reports, 7
Journal articleCartilage oligomeric matrix protein forms protein complexes with synovial lubricin via non-covalent and covalent interactions
S. A. Flowers, Sebastian Kalamajski, Leena Ali, L. I. Björkman, J. R. Raj, et al.
(2017) Osteoarthritis and Cartilage, 25 p.1496-1504
Journal articleFibromodulin deficiency reduces collagen structural network but not glycosaminoglycan content in a syngeneic model of colon carcinoma
P. Olof Olsson, Sebastian Kalamajski, Marco Maccarana, Åke Oldberg, Kristofer Rubin
(2017) PLoS ONE, 12
Journal articleThe Tyrosine Sulfate Domain of Fibromodulin Binds Collagen and Enhances Fibril Formation
Viveka Tillgren, Matthias Mörgelin, Patrik Önnerfjord, Sebastian Kalamajski, Anders Aspberg
(2016) Journal of Biological Chemistry, 291 p.23744-23755
Journal articleThe tyrosine kinase inhibitor imatinib augments extracellular fluid exchange and reduces average collagen fibril diameter in experimental carcinoma
Olof Olsson, Renata Gustafsson, René In 'T Zandt, Tomas Friman, Marco Maccarana, et al.
(2016) Molecular Cancer Therapeutics, 15 p.2455-2464
Journal articleFibromodulin Interacts with Collagen Cross-linking Sites and Activates Lysyl Oxidase.
Sebastian Kalamajski, Dominique Bihan, Arkadiusz Bonna, Kristofer Rubin, Richard W Farndale
(2016) Journal of Biological Chemistry, 291 p.7951-79060
Journal articleNovel Small Leucine-Rich Protein Chondroadherin-like (CHADL) is Expressed in Cartilage and Modulates Chondrocyte Differentiation.
Viveka Tillgren, James C S Ho, Patrik Önnerfjord, Sebastian Kalamajski
(2015) Journal of Biological Chemistry, 290 p.918-925
Journal articleIncreased C-Telopeptide Cross-linking of Tendon Type I Collagen in Fibromodulin-deficient Mice.
Sebastian Kalamajski, Cuiping Liu, Viveka Tillgren, Kristofer Rubin, Åke Oldberg, et al.
(2014) Journal of Biological Chemistry, 289 p.18873-18879
Journal articleFibromodulin Deficiency Reduces Low-Density Lipoprotein Accumulation in Atherosclerotic Plaques in Apolipoprotein E-Null Mice.
Annelie Shami, Renata Gustafsson, Sebastian Kalamajski, Rob Krams, Dolf Segers, et al.
(2012) Arteriosclerosis, Thrombosis and Vascular Biology
Journal articleThe role of small leucine-rich proteoglycans in collagen fibrillogenesis.
Sebastian Kalamajski, Åke Oldberg
(2010) Matrix Biology, 29 p.248-253
Journal articleAsporin competes with decorin for collagen binding, binds calcium and promotes osteoblast collagen mineralization
Sebastian Kalamajski, Anders Aspberg, Karin Lindblom, Dick Heinegård, Åke Oldberg
(2009) Biochemical Journal, 423 p.53-59
Journal articleGene expressions of small leucine-rich repeat proteoglycans and fibulin-5 are decreased in pelvic organ prolapse
Marie Westergren Soderberg, Birgitta Bystrom, Sebastian Kalamajski, Anders Malmström, Gunvor Ekman-Ordeberg
(2009) Molecular Human Reproduction, 15 p.251-257
Journal articleDermatan Sulfate Epimerase 1-Deficient Mice have Reduced Content and Changed Distribution of Iduronic acids in Dermatan Sulfate and an Altered Collagen Structure in Skin.
Marco Maccarana, Sebastian Kalamajski, Mads Kongsgaard, S Peter Magnusson, Åke Oldberg, et al.
(2009) Molecular and Cellular Biology, 29 p.5517-5528
Journal articleHomologous sequence in lumican and fibromodulin LRR 5-7 competes for collagen binding.
Sebastian Kalamajski, Åke Oldberg
(2009) Journal of Biological Chemistry, 284 p.534-539
Journal articleFunctions of small leucine-rich repeat proteoglycans in connective tissues
Sebastian Kalamajski
(2008) Lund University Faculty of Medicine Doctoral Dissertation Series, 2008:30
DissertationCib2 binds integrin a7Bb1D and is reduced in laminin a2 chain deficient muscular dystrophy
Mattias Häger, Bigotti Maria Giulia, Renata Gustafsson, Virginie Carmignac, Johan K Holmberg, et al.
(2008) Journal of Biological Chemistry, 283 p.24760-24769
Journal articleFibromodulin binds collagen type I via Glu-353 and Lys-355 in leucine-rich repeat 11
Sebastian Kalamajski, Åke Oldberg
(2007) Journal of Biological Chemistry, 282 p.26740-26745
Journal articleThe decorin sequence SYIRIADTNIT binds collagen type I.
Sebastian Kalamajski, Anders Aspberg, Åke Oldberg
(2007) Journal of Biological Chemistry, 282 p.16062-16067
Journal articleCollagen-binding proteoglycan fibromodulin can determine stroma matrix structure and fluid balance in experimental carcinoma.
Åke Oldberg, Sebastian Kalamajski, Alexei Salnikov, Linda Stuhr, Matthias Mörgelin, et al.
(2007) Proceedings of the National Academy of Sciences, 104 p.13966-13971
Journal articleA fibronectin-binding protein from Streptococcus equi binds collagen and modulates cell-mediated collagen gel contraction
A Liden, A Karlstrom, J Lannergard, Sebastian Kalamajski, B Guss, et al.
(2006) Biochemical and Biophysical Research Communications, 340 p.604-610
Journal article