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Robert Koivula

Robert Koivula

Assistant researcher

Robert Koivula

Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: rationale and design of the epidemiological studies within the IMI DIRECT Consortium.

Author

  • Robert Koivula
  • Alison Heggie
  • Anna Barnett
  • Henna Cederberg
  • Tue H Hansen
  • Anitra D Koopman
  • Martin Ridderstråle
  • Femke Rutters
  • Henrik Vestergaard
  • Ramneek Gupta
  • Sanna Herrgård
  • Martijn W Heymans
  • Mandy H Perry
  • Simone Rauh
  • Maritta Siloaho
  • Harriet J A Teare
  • Barbara Thorand
  • Jimmy Bell
  • Søren Brunak
  • Gary Frost
  • Bernd Jablonka
  • Andrea Mari
  • Tim J McDonald
  • Jacqueline M Dekker
  • Torben Hansen
  • Andrew Hattersley
  • Markku Laakso
  • Oluf Pedersen
  • Veikko Koivisto
  • Hartmut Ruetten
  • Mark Walker
  • Ewan Pearson
  • Paul Franks

Summary, in English

The DIRECT (Diabetes Research on Patient Stratification) Study is part of a European Union Framework 7 Innovative Medicines Initiative project, a joint undertaking between four industry and 21 academic partners throughout Europe. The Consortium aims to discover and validate biomarkers that: (1) predict the rate of glycaemic deterioration before and after type 2 diabetes onset; (2) predict the response to diabetes therapies; and (3) help stratify type 2 diabetes into clearly definable disease subclasses that can be treated more effectively than without stratification. This paper describes two new prospective cohort studies conducted as part of DIRECT.

Department/s

  • Genetic and Molecular Epidemiology
  • Diabetes - Clinical Obesity
  • EXODIAB: Excellence of Diabetes Research in Sweden
  • EpiHealth: Epidemiology for Health

Publishing year

2014

Language

English

Pages

1132-1142

Publication/Series

Diabetologia

Volume

57

Issue

6

Document type

Journal article

Publisher

Springer

Topic

  • Endocrinology and Diabetes

Status

Published

Research group

  • Genetic and Molecular Epidemiology
  • Diabetes - Clinical Obesity

ISBN/ISSN/Other

  • ISSN: 1432-0428