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Pontus Dunér

Assistant researcher

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IL-25 Inhibits Atherosclerosis Development in Apolipoprotein E Deficient Mice.

Author

  • Polyxeni Mantani
  • Pontus Dunér
  • Eva Bengtsson
  • Ragnar Alm
  • Irena Ljungcrantz
  • Ingrid Söderberg
  • Lena Sundius
  • Fong To
  • Jan Nilsson
  • Harry Björkbacka
  • Gunilla Nordin Fredrikson
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Summary, in English

IL-25 has been implicated in the initiation of type 2 immunity and in the protection against autoimmune inflammatory diseases. Recent studies have identified the novel innate lymphoid type 2 cells (ILC2s) as an IL-25 target cell population. The purpose of this study was to evaluate if IL-25 has any influence on atherosclerosis development in mice.

Department/s

  • Cardiovascular Research - Immunity and Atherosclerosis
  • EXODIAB: Excellence of Diabetes Research in Sweden
  • EpiHealth: Epidemiology for Health

Publishing year

2015

Language

English

Publication/Series

PLoS ONE

Volume

10

Issue

1

Document type

Journal article

Publisher

Public Library of Science (PLoS)

Topic

  • Cardiac and Cardiovascular Systems

Status

Published

Research group

  • Cardiovascular Research - Immunity and Atherosclerosis

ISBN/ISSN/Other

  • ISSN: 1932-6203