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Molecularly imprinted polymer formats for capillary electrochromatography

Author:
  • Jakob Nilsson
  • Peter Spégel
  • Staffan Nilsson
Publishing year: 2004
Language: English
Pages: 3-12
Publication/Series: Journal of Chromatography. B
Volume: 804
Issue: 1
Document type: Journal article review
Publisher: Elsevier

Abstract english

The research aimed towards the adaptation of molecularly imprinted polymers (MIPs) to the capillary format and the use of these highly selective matrices for capillary electrochromatography (CEC) is reviewed in this article. The MIP is prepared by incorporation of a template molecule into a polymerization protocol. After polymerization and extraction of the template from the resulting polymer a highly selective material with recognition cavities complementary to the template in size, shape and chemical functionality is obtained. MIPs have been used as recognition elements in several different analytical techniques. In combination with CEC a novel separation system with a unique selectivity towards a predetermined target (the template) is achieved. The merge of molecular imprinting technology (MIT) and CEC have introduced several interesting polymer formats, due to the adaptation of the MIP to the miniaturized capillary format. The polymer formats can be classified according to their preparation protocols and appearance into three conceptually different categories, i.e. the monolith, the coating and the nanoparticles. The preparation protocols, characteristics and applications of these formats will be discussed.

Keywords

  • Analytical Chemistry
  • Molecularly imprinted polymers
  • Reviews

Other

Published
  • ISSN: 1873-376X
Peter Spegel
E-mail: peter [dot] spegel [at] chem [dot] lu [dot] se

Researcher

Centre for Analysis and Synthesis

1

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