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Paul Franks

Paul Franks

Principal investigator

Paul Franks

Maternal Physical Activity and Insulin Action in Pregnancy and Their Relationships With Infant Body Composition.


  • Jeremy Pomeroy
  • Frida Renström
  • Anna M Gradmark
  • Ingrid Mogren
  • Margareta Persson
  • Les Bluck
  • Antony Wright
  • Steven E Kahn
  • Magnus Domellöf
  • Paul Franks

Summary, in English

OBJECTIVEWe sought to assess the association between maternal gestational physical activity and insulin action and body composition in early infancy.RESEARCH DESIGN AND METHODSAt 28-32 weeks, gestation, pregnant women participating in an observational study in Sweden underwent assessments of height, weight, and body composition, an oral glucose tolerance test, and 10 days of objective physical activity assessment. Thirty mothers and infants returned at 11-19 weeks, postpartum. Infants underwent assessments of weight, length, and body composition.RESULTSEarly insulin response was correlated with total physical activity (r = -0.47; P = 0.007). Early insulin response (r = -0.36; P = 0.045) and total physical activity (r = 0.52; P = 0.037) were also correlated with infant fat-free mass. No maternal variable was significantly correlated with infant adiposity.CONCLUSIONSThe relationships between maternal physical activity, insulin response, and infant fat-free mass suggest that physical activity during pregnancy may affect metabolic outcomes in the mother and her offspring.


  • Genetic and Molecular Epidemiology
  • Clinical Chemistry, Malmö
  • EXODIAB: Excellence in Diabetes Research in Sweden
  • EpiHealth: Epidemiology for Health

Publishing year





Diabetes Care

Document type

Journal article


American Diabetes Association


  • Endocrinology and Diabetes



Research group

  • Genetic and Molecular Epidemiology
  • Clinical Chemistry, Malmö


  • ISSN: 1935-5548