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Maternal Physical Activity and Insulin Action in Pregnancy and Their Relationships With Infant Body Composition.

  • Jeremy Pomeroy
  • Frida Renström
  • Anna M Gradmark
  • Ingrid Mogren
  • Margareta Persson
  • Les Bluck
  • Antony Wright
  • Steven E Kahn
  • Magnus Domellöf
  • Paul Franks
Publishing year: 2012-09-10
Language: English
Publication/Series: Diabetes Care
Document type: Journal article
Publisher: American Diabetes Association

Abstract english

OBJECTIVEWe sought to assess the association between maternal gestational physical activity and insulin action and body composition in early infancy.RESEARCH DESIGN AND METHODSAt 28-32 weeks, gestation, pregnant women participating in an observational study in Sweden underwent assessments of height, weight, and body composition, an oral glucose tolerance test, and 10 days of objective physical activity assessment. Thirty mothers and infants returned at 11-19 weeks, postpartum. Infants underwent assessments of weight, length, and body composition.RESULTSEarly insulin response was correlated with total physical activity (r = -0.47; P = 0.007). Early insulin response (r = -0.36; P = 0.045) and total physical activity (r = 0.52; P = 0.037) were also correlated with infant fat-free mass. No maternal variable was significantly correlated with infant adiposity.CONCLUSIONSThe relationships between maternal physical activity, insulin response, and infant fat-free mass suggest that physical activity during pregnancy may affect metabolic outcomes in the mother and her offspring.


  • Endocrinology and Diabetes


  • Genetic and Molecular Epidemiology
  • Clinical Chemistry, Malmö
  • ISSN: 1935-5548
Paul Franks
E-mail: paul [dot] franks [at] med [dot] lu [dot] se

Principal investigator

Genetic and Molecular Epidemiology

+46 40 39 11 49



Lund University Diabetes Centre, CRC, SUS Malmö, Entrance 72, House 91:12. SE-205 02 Malmö. Telephone: +46 40 39 10 00