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Paul Franks

Paul Franks

Principal investigator

Paul Franks

Cancer and Risk of COVID-19 Through a General Community Survey

Author

  • Karla A. Lee
  • Wenjie Ma
  • Daniel R. Sikavi
  • David A. Drew
  • Long H. Nguyen
  • Ruth C.E. Bowyer
  • M. Jorge Cardoso
  • Tove Fall
  • Maxim B. Freidin
  • Maria Gomez
  • Mark Graham
  • Chuan Guo Guo
  • Amit D. Joshi
  • Sohee Kwon
  • Chun Han Lo
  • Mary Ni Lochlainn
  • Cristina Menni
  • Benjamin Murray
  • Raaj Mehta
  • Mingyang Song
  • Carole H. Sudre
  • Veronique Bataille
  • Thomas Varsavsky
  • Alessia Visconti
  • Paul W. Franks
  • Jonathan Wolf
  • Claire J. Steves
  • Sebastien Ourselin
  • Tim D. Spector
  • Andrew T. Chan

Summary, in English

Individuals with cancer may be at high risk for coronavirus disease 2019 (COVID-19) and adverse outcomes. However, evidence from large population-based studies examining whether cancer and cancer-related therapy exacerbates the risk of COVID-19 infection is still limited. Data were collected from the COVID Symptom Study smartphone application since March 29 through May 8, 2020. Among 23,266 participants with cancer and 1,784,293 without cancer, we documented 10,404 reports of a positive COVID-19 test. Compared with participants without cancer, those living with cancer had a 60% increased risk of a positive COVID-19 test. Among patients with cancer, current treatment with chemotherapy or immunotherapy was associated with a 2.2-fold increased risk of a positive test. The association between cancer and COVID-19 infection was stronger among participants >65 years and males. Future studies are needed to identify subgroups by tumor types and treatment regimens who are particularly at risk for COVID-19 infection and adverse outcomes.

Department/s

  • Genomics, Diabetes and Endocrinology
  • Diabetic Complications
  • EXODIAB: Excellence in Diabetes Research in Sweden
  • Genetic and Molecular Epidemiology
  • EpiHealth: Epidemiology for Health

Publishing year

2021

Language

English

Publication/Series

Oncologist

Volume

26

Issue

1

Document type

Journal article

Publisher

AlphaMed Press

Topic

  • Cancer and Oncology
  • Public Health, Global Health, Social Medicine and Epidemiology

Keywords

  • Covid-19
  • SARS-CoV-2

Status

Published

Project

  • COVID Symptom Study Sweden

Research group

  • Genomics, Diabetes and Endocrinology
  • Diabetic Complications
  • Genetic and Molecular Epidemiology

ISBN/ISSN/Other

  • ISSN: 1083-7159