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Paul Franks

Paul Franks

Principal investigator

Paul Franks

Common variation at PPARGC1A/B and change in body composition and metabolic traits following preventive interventions: the Diabetes Prevention Program.

Author

  • Paul Franks
  • Costas A Christophi
  • Kathleen A Jablonski
  • Liana K Billings
  • Linda M Delahanty
  • Edward S Horton
  • William C Knowler
  • Jose C Florez

Summary, in English

PPARGC1A and PPARGCB encode transcriptional coactivators that regulate numerous metabolic processes. We tested associations and treatment (i.e. metformin or lifestyle modification) interactions with metabolic traits in the Diabetes Prevention Program, a randomised controlled trial in persons at high risk of type 2 diabetes.

Department/s

  • Genetic and Molecular Epidemiology
  • EXODIAB: Excellence in Diabetes Research in Sweden
  • EpiHealth: Epidemiology for Health

Publishing year

2014

Language

English

Pages

485-490

Publication/Series

Diabetologia

Volume

57

Issue

3

Document type

Journal article

Publisher

Springer

Topic

  • Endocrinology and Diabetes

Status

Published

Research group

  • Genetic and Molecular Epidemiology

ISBN/ISSN/Other

  • ISSN: 1432-0428