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Paul Franks

Paul Franks

Principal investigator

Paul Franks

Cross-Sectional Associations of Objectively Measured Physical Activity, Cardiorespiratory Fitness and Anthropometry in European Adults


  • Angelika Wientzek
  • Maria-Jose Tormo Diaz
  • Jose Maria Huerta Castano
  • Pilar Amiano
  • Larraitz Arriola
  • Kim Overvad
  • Jane Nautrup Ostergaard
  • Marie-Aline Charles
  • Guy Fagherazzi
  • Domenico Palli
  • Benedetta Bendinelli
  • Guri Skeie
  • Kristin Benjaminsen Borch
  • Wanda Wendel-Vos
  • Ellen de Hollander
  • Anne M. May
  • Marjolein E. M. den Ouden
  • Antonia Trichopoulou
  • Elissavet Valanou
  • Stefan Soederberg
  • Paul Franks
  • Soren Brage
  • Matthaus Vigl
  • Heiner Boeing
  • Ulf Ekelund

Summary, in English

Objective: To quantify the independent associations between objectively measured physical activity (PA), cardiorespiratory fitness (CRF), and anthropometry in European men and women. Methods: 2,056 volunteers from 12 centers across Europe were fitted with a heart rate and movement sensor at 2 visits 4 months apart for a total of 8 days. CRF (ml/kg/min) was estimated from an 8 minute ramped step test. A cross-sectional analysis of the independent associations between objectively measured PA (m/s(2)/d), moderate and vigorous physical activity (MVPA) (% time/d), sedentary time (% time/d), CRF, and anthropometry using sex stratified multiple linear regression was performed. Results: In mutually adjusted models, CRF, PA, and MVPA were inversely associated with all anthropometric markers in women. In men, CRF, PA, and MVPA were inversely associated with BMI, whereas only CRF was significantly associated with the other anthropometric markers. Sedentary time was positively associated with all anthropometric markers, however, after adjustment for CRF significant in women only. Conclusion: CRF, PA, MVPA, and sedentary time are differently associated with anthropometric markers in men and women. CRF appears to attenuate associations between PA, MVPA, and sedentary time. These observations may have implications for prevention of obesity.


  • Genetic and Molecular Epidemiology
  • EXODIAB: Excellence in Diabetes Research in Sweden
  • EpiHealth: Epidemiology for Health

Publishing year












Document type

Journal article


Nature Publishing Group


  • Nutrition and Dietetics



Research group

  • Genetic and Molecular Epidemiology


  • ISSN: 1930-739X