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The Association of Multiple Biomarkers of Iron Metabolism and Type 2 Diabetes: The EPIC-InterAct Study.

Author:
  • Clara Podmore
  • Karina Meidtner
  • Matthias B Schulze
  • Robert A Scott
  • Anna Ramond
  • Adam S Butterworth
  • Emanuele Di Angelantonio
  • John Danesh
  • Larraitz Arriola
  • Aurelio Barricarte
  • Heiner Boeing
  • Françoise Clavel-Chapelon
  • Amanda J Cross
  • Christina C Dahm
  • Guy Fagherazzi
  • Paul Franks
  • Diana Gavrila
  • Sara Grioni
  • Marc J Gunter
  • Gaelle Gusto
  • Paula Jakszyn
  • Verena Katzke
  • Timothy J Key
  • Tilman Kühn
  • Amalia Mattiello
  • Peter Nilsson
  • Anja Olsen
  • Kim Overvad
  • Domenico Palli
  • J Ramón Quirós
  • Olov Rolandsson
  • Carlotta Sacerdote
  • Emilio Sánchez-Cantalejo
  • Nadia Slimani
  • Ivonne Sluijs
  • Annemieke M W Spijkerman
  • Anne Tjonneland
  • Rosario Tumino
  • Daphne L van der A
  • Yvonne T van der Schouw
  • Edith J M Feskens
  • Nita G Forouhi
  • Stephen J Sharp
  • Elio Riboli
  • Claudia Langenberg
  • Nicholas J Wareham
Publishing year: 2016-04
Language: English
Pages: 572-581
Publication/Series: Diabetes Care
Volume: 39
Issue: 4
Document type: Journal article
Publisher: American Diabetes Association

Abstract english

Observational studies show an association between ferritin and type 2 diabetes (T2D), suggesting a role of high iron stores in T2D development. However, ferritin is influenced by factors other than iron stores, which is less the case for other biomarkers of iron metabolism. We investigate associations of ferritin, transferrin saturation (TSAT), serum iron, and transferrin with T2D incidence to clarify the role of iron in the pathogenesis of T2D.

Keywords

  • Endocrinology and Diabetes

Other

Published
  • Genetic and Molecular Epidemiology
  • Internal Medicine
  • ISSN: 1935-5548
Paul Franks
E-mail: paul [dot] franks [at] med [dot] lu [dot] se

Principal investigator

Genetic and Molecular Epidemiology

+46 40 39 11 49

60-12-021

33

Lund University Diabetes Centre, CRC, SUS Malmö, Entrance 72, House 91:12. SE-205 02 Malmö. Telephone: +46 40 39 10 00