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Olof Gidlöf

Research project participant

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Non-contact acoustic capture of platelet-derived microparticles from small plasma volumes

Author

  • Mikael Evander
  • Olof Gidlöf
  • Björn Olde
  • David Erlinge
  • Thomas Laurell

Summary, in English

This paper presents the characterization and optimization of acoustic capture of platelet-derived microparticles (PMPs) from human plasma. The technique is compared to a standard preparation protocol using differential centrifugation on biobank samples from patients with ST-elevation myocardial infarction (STEMI). The main advantages of this new method are the capability of rapidly capturing microvesicles from small sample volumes and the potential to extract intact vesicles for downstream processing or handling.

Department/s

  • Department of Biomedical Engineering
  • Molecular Cardiology

Publishing year

2015

Language

English

Pages

469-471

Publication/Series

MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences

Document type

Conference paper

Publisher

Chemical and Biological Microsystems Society

Topic

  • Biomedical Laboratory Science/Technology

Keywords

  • Acoustic trapping
  • Acoustofluidics
  • Enrichment
  • Extracellular vesicles
  • Microparticles

Conference name

19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015

Conference date

2015-10-25 - 2015-10-29

Conference place

Gyeongju, Korea, Republic of

Status

Published

Research group

  • Molecular Cardiology

ISBN/ISSN/Other

  • ISBN: 9780979806483