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Olle Melander

Principal investigator

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Smoking modifies the associated increased risk of future cardiovascular disease by genetic variation on chromosome 9p21.

Author

  • Viktor Hamrefors
  • Bo Hedblad
  • George Hindy
  • Gustav Smith
  • Peter Almgren
  • Gunnar Engström
  • Marketa Sjögren
  • Klas Gränsbo
  • Marju Orho-Melander
  • Olle Melander

Summary, in English

Genetic predisposition for cardiovascular disease (CVD) is likely to be modified by environmental exposures. We tested if the associated risk of CVD and CVD-mortality by the single nucleotide polymorphism rs4977574 on chromosome 9p21 is modified by life-style factors.

Department/s

  • Cardiovascular Research - Hypertension
  • Cardiovascular Research - Epidemiology
  • Diabetes - Cardiovascular Disease
  • Cardiology
  • Genomics, Diabetes and Endocrinology
  • EXODIAB: Excellence in Diabetes Research in Sweden
  • EpiHealth: Epidemiology for Health

Publishing year

2014

Language

English

Publication/Series

PLoS ONE

Volume

9

Issue

1

Document type

Journal article

Publisher

Public Library of Science

Topic

  • Endocrinology and Diabetes
  • Cardiac and Cardiovascular Systems

Status

Published

Research group

  • Cardiovascular Research - Hypertension
  • Cardiovascular Research - Epidemiology
  • Diabetes - Cardiovascular Disease
  • Genomics, Diabetes and Endocrinology

ISBN/ISSN/Other

  • ISSN: 1932-6203