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Olle Melander

Principal investigator

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Twelve-Single Nucleotide Polymorphism Genetic Risk Score Identifies Individuals at Increased Risk for Future Atrial Fibrillation and Stroke.

Author

  • Hayato Tada
  • Dov Shiffman
  • Gustav Smith
  • Marketa Sjögren
  • Steven A Lubitz
  • Patrick T Ellinor
  • Judy Z Louie
  • Joseph J Catanese
  • Gunnar Engström
  • James J Devlin
  • Sekar Kathiresan
  • Olle Melander

Summary, in English

Atrial fibrillation (AF) is prevalent and there is a clinical need for biomarkers to identify individuals at higher risk for AF. Fixed throughout a life course and assayable early in life, genetic biomarkers may meet this need. Here, we investigate whether multiple single nucleotide polymorphisms together as an AF genetic risk score (AF-GRS) can improve prediction of one's risk for AF.

Department/s

  • Cardiology
  • Cardiovascular Research - Hypertension
  • Cardiovascular Research - Epidemiology
  • EXODIAB: Excellence in Diabetes Research in Sweden
  • EpiHealth: Epidemiology for Health

Publishing year

2014

Language

English

Pages

2856-2856

Publication/Series

Stroke: a journal of cerebral circulation

Volume

45

Issue

10

Document type

Journal article

Publisher

American Heart Association

Topic

  • Neurology

Status

Published

Research group

  • Cardiovascular Research - Hypertension
  • Cardiovascular Research - Epidemiology

ISBN/ISSN/Other

  • ISSN: 1524-4628