Your browser has javascript turned off or blocked. This will lead to some parts of our website to not work properly or at all. Turn on javascript for best performance.

The browser you are using is not supported by this website. All versions of Internet Explorer are no longer supported, either by us or Microsoft (read more here: https://www.microsoft.com/en-us/microsoft-365/windows/end-of-ie-support).

Please use a modern browser to fully experience our website, such as the newest versions of Edge, Chrome, Firefox or Safari etc.

Default user image.

Olle Melander

Principal investigator

Default user image.

WDR12, a Member of Nucleolar PeBoW-Complex, Is Up-Regulated in Failing Hearts and Causes Deterioration of Cardiac Function.

Author

  • Anne-Mari Moilanen
  • Jaana Rysä
  • Leena Kaikkonen
  • Teemu Karvonen
  • Erja Mustonen
  • Raisa Serpi
  • Zoltán Szabó
  • Olli Tenhunen
  • Zsolt Bagyura
  • Juha Näpänkangas
  • Pauli Ohukainen
  • Pasi Tavi
  • Risto Kerkelä
  • Margrét Leosdottir
  • Björn Wahlstrand
  • Thomas Hedner
  • Olle Melander
  • Heikki Ruskoaho

Summary, in English

In a recent genome-wide association study, WD-repeat domain 12 (WDR12) was associated with early-onset myocardial infarction (MI). However, the function of WDR12 in the heart is unknown.

Department/s

  • Internal Medicine - Epidemiology
  • Cardiovascular Research - Hypertension
  • EXODIAB: Excellence in Diabetes Research in Sweden
  • EpiHealth: Epidemiology for Health

Publishing year

2015

Language

English

Publication/Series

PLoS ONE

Volume

10

Issue

4

Document type

Journal article

Publisher

Public Library of Science

Topic

  • Other Clinical Medicine
  • Cardiac and Cardiovascular Systems

Status

Published

Research group

  • Internal Medicine - Epidemiology
  • Cardiovascular Research - Hypertension

ISBN/ISSN/Other

  • ISSN: 1932-6203