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Olle Melander

Principal investigator

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Expression Quantitative Trait Loci Acting Across Multiple Tissues Are Enriched in Inherited Risk for Coronary Artery Disease.

Author

  • Hassan Foroughi Asl
  • Husain A Talukdar
  • Alida S D Kindt
  • Rajeev K Jain
  • Raili Ermel
  • Arno Ruusalepp
  • Khanh-Dung H Nguyen
  • Radu Dobrin
  • Dermot F Reilly
  • Heribert Schunkert
  • Nilesh J Samani
  • Ingrid Brænne
  • Jeanette Erdmann
  • Olle Melander
  • Jianlong Qi
  • Torbjörn Ivert
  • Josefin Skogsberg
  • Eric E Schadt
  • Tom Michoel
  • Johan L M Björkegren

Summary, in English

-Despite recent discoveries of new genetic risk factors, the majority of risk for coronary artery disease (CAD) remains elusive. As the most proximal sensor of DNA variation, RNA abundance can help identify subpopulations of genetic variants active in and across tissues mediating CAD risk through gene expression.

Department/s

  • Cardiovascular Research - Hypertension
  • EXODIAB: Excellence in Diabetes Research in Sweden
  • EpiHealth: Epidemiology for Health

Publishing year

2015

Language

English

Pages

305-305

Publication/Series

Circulation: Cardiovascular Genetics

Volume

8

Issue

2

Document type

Journal article

Publisher

American Heart Association

Topic

  • Cardiac and Cardiovascular Systems

Status

Published

Research group

  • Cardiovascular Research - Hypertension

ISBN/ISSN/Other

  • ISSN: 1942-325X