Olle Melander

Endogenous incretin levels and risk of first incident cancer: a prospective cohort study

Amra Jujic, Christopher Godina, Mattias Belting, Olle Melander, Jens Juul Holst, et al.
(2023) Scientific Reports, 13 p.1-11
Journal article

Malmö POTS symptom score : Assessing symptom burden in postural orthostatic tachycardia syndrome

Jasmina Medic Spahic, Viktor Hamrefors, Madeleine Johansson, Fabrizio Ricci, Olle Melander, et al.
(2023) Journal of Internal Medicine, 293 p.91-99
Journal article

Increased soluble urokinase plasminogen activator levels modulate monocyte function to promote atherosclerosis

George Hindy, Daniel J. Tyrrell, Alexi Vasbinder, Changli Wei, Feriel Presswalla, et al.
(2022) Journal of Clinical Investigation, 132 p.1-14
Journal article

A healthy dietary metabolic signature is associated with a lower risk for type 2 diabetes and coronary artery disease

Einar Smith, Ulrika Ericson, Sophie Hellstrand, Marju Orho-Melander, Peter M. Nilsson, et al.
(2022) BMC Medicine, 20
Journal article

Prostate cancer polygenic risk score and prediction of lethal prostate cancer

Robert J. Klein, Emily Vertosick, Dan Sjoberg, David Ulmert, Ann Charlotte Rönn, et al.
(2022) NPJ precision oncology, 6
Journal article

Malmö POTS symptom score : Assessing symptom burden in postural orthostatic tachycardia syndrome

Jasmina Medic Spahic, Viktor Hamrefors, Madeleine Johansson, Fabrizio Ricci, Olle Melander, et al.
(2022) European Heart Journal, Supplement, 24
Conference paper: abstract

Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants

Krishna G Aragam, George Hindy, Satoshi Koyama, Olle Melander, Marju Orho-Melander, et al.
(2022) Nature Genetics, 54 p.1803-1815
Journal article

Calcium, Its Regulatory Hormones, and Their Causal Role on Blood Pressure : A Two-Sample Mendelian Randomization Study

Alice Giontella, Luca A. Lotta, Aris Baras, Pietro Minuz, Dipender Gill, et al.
(2022) The Journal of clinical endocrinology and metabolism, 107 p.3080-3085
Journal article

Rare genetic variants explain missing heritability in smoking

S.-K. Jang, O. Melander, S. Vrieze
(2022) Nature Human Behaviour, 6 p.1577-1586
Journal article

The effect of a randomised controlled lifestyle intervention on weight loss and plasma proneurotensin

Louise Bennet, Ayesha Fawad, Joachim Struck, Sara Lönn Larsson, Andreas Bergmann, et al.
(2022) BMC Endocrine Disorders, 22
Journal article

Prevalence and Ascertainment of Dementia Cases in the Malmö Diet and Cancer Study

Katarina Nägga, Vanja Bränsvik, Erik Stomrud, Olle Melander, Peter M Nilsson, et al.
(2022) Journal of Alzheimer's Disease Reports, 6 p.529-538
Journal article

Physical activity attenuates but does not eliminate coronary heart disease risk amongst adults with risk factors : EPIC-CVD case-cohort study

Melony C. Fortuin-de Smidt, Maquins Odhiambo Sewe, Camille Lassale, Elisabete Weiderpass, Jonas Andersson, et al.
(2022) European Journal of Preventive Cardiology, 29 p.1618-1629
Journal article

Genome-wide interaction analysis identified low-frequency variants with sex disparity in lung cancer risk

Y. Li, O. Melander, H. Brunnström, C.I. Amos
(2022) Human Molecular Genetics, 31 p.2831-2843
Journal article

The relationship between blood pressure and risk of renal cell carcinoma

Karine Alcala, Daniela Mariosa, Karl Smith-Byrne, Dariush Nasrollahzadeh Nesheli, Robert Carreras-Torres, et al.
(2022) International Journal of Epidemiology, 51 p.1317-1327
Journal article

Germline Mutations in CIDEB and Protection against Liver Disease

Niek Verweij, Mary E. Haas, Jonas B. Nielsen, Olukayode A. Sosina, Minhee Kim, et al.
(2022) New England Journal of Medicine, 387 p.332-344
Journal article

Galectin-4 levels in hospitalized versus non-hospitalized subjects with obesity : the Malmö Preventive Project

Johan Korduner, Hannes Holm, Amra Jujic, Olle Melander, Manan Pareek, et al.
(2022) Cardiovascular Diabetology, 21
Journal article

Proteomic Profiles of Body Mass Index and Waist-to-Hip Ratio and Their Role in Incidence of Diabetes

Xue Bao, Biao Xu, Songjiang Yin, Jingxue Pan, Peter M. Nilsson, et al.
(2022) Journal of Clinical Endocrinology and Metabolism, 107 p.2982-2990
Journal article

Population-scale analysis of common and rare genetic variation associated with hearing loss in adults

Kavita Praveen, Lee Dobbyn, Lauren Gurski, Ariane H. Ayer, Jeffrey Staples, et al.
(2022) Communications Biology, 5 p.540-540
Journal article

Hospitalisations with infectious disease diagnoses in somatic healthcare between 1998 and 2019 : A nationwide, register-based study in Swedish adults

Gustav Torisson, Mari Rosenqvist, Olle Melander, Fredrik Resman
(2022) The Lancet Regional Health - Europe, 16
Journal article

Outcomes of Primary vs. Delayed Strategy of Implanting a Cardiac Monitor for Unexplained Syncope

Ekrem Yasa, Theodoros Intzilakis, Fabrizio Ricci, Olle Melander, Viktor Hamrefors, et al.
(2022) Journal of Clinical Medicine, 11
Journal article

The inverse association between a fish consumption biomarker and gingival inflammation and periodontitis : A population-based study

Filip Ottosson, Lina Hultgren, Celine Fernandez, Gunnar Engström, Marju Orho-Melander, et al.
(2022) Journal of Clinical Periodontology, 49 p.353-361
Journal article

Thrombomodulin (THBD) gene variants and thrombotic risk in a population-based cohort study

Eric Manderstedt, Christer Halldén, Christina Lind-Halldén, Johan Elf, Peter J. Svensson, et al.
(2022) Journal of Thrombosis and Haemostasis, 20 p.929-935
Journal article

Tumor Suppressor Par-4 Regulates Complement Factor C3 and Obesity

Nathalia Araujo, James Sledziona, Sunil K. Noothi, Ravshan Burikhanov, Nikhil Hebbar, et al.
(2022) Frontiers in Oncology, 12
Journal article

Metabolome-Defined Obesity and the Risk of Future Type 2 Diabetes and Mortality

Filip Ottosson, Einar Smith, Ulrika Ericson, Louise Brunkwall, Marju Orho-Melander, et al.
(2022) Diabetes Care, 45 p.1260-1267
Journal article

Lipidomic risk scores are independent of polygenic risk scores and can predict incidence of diabetes and cardiovascular disease in a large population cohort

Chris Lauber, Mathias J. Gerl, Christian Klose, Filip Ottosson, Olle Melander, et al.
(2022) PLoS Biology, 20
Journal article

Multi-ancestry genome-wide association study of gestational diabetes mellitus highlights genetic links with type 2 diabetes

Natalia Pervjakova, Gunn-Helen Moen, Maria-Carolina Borges, Teresa Ferreira, James P Cook, et al.
(2022) Human Molecular Genetics, 31 p.3377-3391
Journal article

Plasma Proneurotensin and Prediction of Cause-Specific Mortality in a Middle-aged Cohort During Long-term Follow-up

Ayesha Fawad, Andreas Bergmann, Janin Schulte, Zahra A Butt, Peter M Nilsson, et al.
(2022) The Journal of clinical endocrinology and metabolism, 107 p.1204-1211
Journal article

New Insights in the Control of Fat Homeostasis : The Role of Neurotensin

Ilaria Barchetta, Marco Giorgio Baroni, Olle Melander, Maria Gisella Cavallo
(2022) International Journal of Molecular Sciences, 23
Journal article review

Classic Thrombophilias and Thrombotic Risk Among Middle-Aged and Older Adults : A Population-Based Cohort Study

Eric Manderstedt, Christina Lind-Halldén, Christer Halldén, Johan Elf, Peter J. Svensson, et al.
(2022) Journal of the American Heart Association, 11
Journal article

Iam hiQ-a novel pair of accuracy indices for imputed genotypes

Albert Rosenberger, Viola Tozzi, Heike Bickeböller
(2022) BMC Bioinformatics, 23
Journal article

Prospective Comparison of Plasma Biomarker and Traditional Risk Factor Profiles for Incident Isolated Atherosclerotic Disease and Incident Isolated Abdominal Aortic Aneurysm

Stefan Acosta, Shahab Fatemi, Olle Melander, Gunnar Engström, Anders Gottsäter
(2022) Frontiers in Cardiovascular Medicine, 8 p.1-9
Journal article

Bioactive adrenomedullin a prognostic biomarker in patients with mild to moderate dyspnea at the emergency department : an observational study

Kevin Bronton, Torgny Wessman, Klas Gränsbo, Janin Schulte, Oliver Hartmann, et al.
(2022) Internal and Emergency Medicine, 17 p.541-550
Journal article

The association between length of stay in the emergency department and short-term mortality

Torgny Wessman, Johan Ärnlöv, Axel Carl Carlsson, Ulf Ekelund, Per Wändell, et al.
(2022) Internal and Emergency Medicine, 17 p.233-240
Journal article

Associations between biomarkers of multimorbidity burden and mortality risk among patients with acute dyspnea

Torgny Wessman, Rafid Tofik, Thoralph Ruge, Olle Melander
(2022) Internal and Emergency Medicine, 17 p.559-567
Journal article

High levels of autoantibodies against apoB100 p210 are associated with lower incidence of atrial fibrillation in women

Kari Anne Sveen, Gustav Smith, Harry Björkbacka, Marju Orho-Melander, Gunnar Engström, et al.
(2022) Journal of Internal Medicine, 291 p.207-217
Journal article

Circulating Biomarkers Predict Symptomatic but Not Asymptomatic Carotid Artery Stenosis

Shahab Fatemi, Stefan Acosta, Moncef Zarrouk, Gunnar Engström, Olle Melander, et al.
(2022) Cerebrovascular Diseases, 51 p.623-629
Journal article

Seasonal variation of vasopressin and its relevance for the winter peak of cardiometabolic disease : A pooled analysis of five cohorts

Sofia Enhörning, Olle Melander, Gunnar Engström, Sölve Elmståhl, Lars Lind, et al.
(2022) Journal of Internal Medicine, 292 p.365-376
Journal article

Circulating Hepatocyte Growth Factor Reflects Activation of Vascular Repair in Response to Stress

Yihong Chen, Junyan Shen, Anna Hultgårdh Nilsson, Isabel Goncalves, Andreas Edsfeldt, et al.
(2022) JACC: Basic to Translational Science, 7 p.747-762
Journal article

Genetic Variation Interacts with Selenium Exposure Regarding Breast Cancer Risk: Assessing Dietary Intake, Serum Levels and Genetically Elevated Selenium Levels

Malte Sandsveden, Ylva Bengtsson, Olle Melander, Ann H. Rosendahl, Jonas Manjer
(2022) Nutrients, 14
Journal article

Association Between Dietary Habits in Midlife With Dementia Incidence Over a 20-Year Period

Isabelle Glans, Emily Sonestedt, Katarina Nägga, Anna-Märta Gustavsson, Esther González-Padilla, et al.
(2022) Neurology
Journal article

High pro‑neurotensin levels in individuals with type 1 diabetes associate with the development of cardiovascular risk factors at follow‑up

Flavia Agata Cimini, Ilaria Barchetta, Laura Bertoccini, Valentina Ceccarelli, Marco Giorgio Baroni, et al.
(2022) Acta Diabetologica, 59 p.49-56
Journal article

Milk intake and incident stroke and coronary heart disease in populations of European descent : A Mendelian Randomization study

L. E.T. Vissers, I. Sluijs, S. Burgess, N. G. Forouhi, H. Freisling, et al.
(2022) British Journal of Nutrition, 128 p.1789-1797
Journal article

Circulating lipids and breast cancer prognosis in the Malmö diet and cancer study

Sixten Harborg, Thomas P. Ahern, Maria Feldt, Ann H. Rosendahl, Deirdre Cronin-Fenton, et al.
(2022) Breast Cancer Research and Treatment, 191 p.611-621
Journal article

Self-care Management Intervention in Heart Failure (SMART-HF) : A Multicenter Randomized Controlled Trial

DANIEL Sahlin, BABAK REZANEZAD, MARIE LOUISE EDVINSSON, ERASUMS BACHUS, O. MELANDER, et al.
(2022) Journal of Cardiac Failure, 28 p.3-12
Journal article

Circulating Levels of the Cardiovascular Biomarkers ST2 and Adrenomedullin Predict Outcome within a Randomized Phase III Lung Cancer Trial (RASTEN)

Emelie Gezelius, Pär Ola Bendahl, Widet Gallo, Kelin Gonçalves de Oliveira, Lars Ek, et al.
(2022) Cancers, 14 p.1-14
Journal article

Thrombotic Risk Determined by Protein C Receptor (PROCR) Variants among Middle-Aged and Older Adults : A Population-Based Cohort Study

Eric Manderstedt, Christer Halldén, Christina Lind-Halldén, Johan Elf, Peter J. Svensson, et al.
(2022) Thrombosis and Haemostasis, 122 p.1326-1332
Journal article

Thrombotic risk determined by rare and common SERPINA1 variants in a population-based cohort study

E. Manderstedt, Christer Halldén, Christina Lind-Halldén, J. Elf, P.J. Svensson, et al.
(2022) Journal of Thrombosis and Haemostasis, 20
Journal article

The association between plasma metabolites and future risk of all-cause mortality

Yingxiao Yan, Einar Smith, Olle Melander, Filip Ottosson
(2022) Journal of Internal Medicine, 292 p.804-815
Journal article

Bioactive adrenomedullin in sepsis patients in the emergency department is associated with mortality, organ failure and admission to intensive care

Oscar Lundberg, Mari Rosenqvist, Kevin Bronton, Janin Schulte, Hans Friberg, et al.
(2022) PLoS ONE, 17 p.1-16
Journal article

Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals

T.W. Winkler, C.-A. Schulz, M. Orho-Melander, O. Melander, Iris M. Heid
(2022) Communications Biology, 5
Journal article

Multiancestry exome sequencing reveals INHBE mutations associated with favorable fat distribution and protection from diabetes

P. Akbari, A. Giontella, M. Orho-Melander, O. Melander, Luca A. Lotta
(2022) Nature Communications, 13
Journal article

Cross-ancestry genome-wide meta-analysis of 61,047 cases and 947,237 controls identifies new susceptibility loci contributing to lung cancer

J. Byun, O. Melander, H. Brunnstrom, C.I. Amos
(2022) Nature Genetics, 54 p.1167-1177
Journal article

Genetically Determined Reproductive Aging and Coronary Heart Disease: A Bidirectional 2-sample Mendelian Randomization

V. Dam, O. Melander, Y.T. Van Der Schouw
(2022) Journal of Clinical Endocrinology and Metabolism, 107 p.2952-2961
Journal article

Genetic loci and prioritization of genes for kidney function decline derived from a meta-analysis of 62 longitudinal genome-wide association studies

M. Gorski, O. Melander, M. Orho-Melander, C.-A. Schulz, I.M. Heid
(2022) Kidney International , p.624-639
Journal article

Bioactive adrenomedullin for assessment of venous congestion in heart failure

Anna Egerstedt, Tomasz Czuba, Kevin Bronton, Carl Lejonberg, Thoralph Ruge, et al.
(2022) ESC Heart Failure, 9 p.3543-3555
Journal article

Interaction between blood pressure and genetic risk score for bladder cancer, and risk of urothelial carcinoma in men

Stanley Teleka, Marju Orho-Melander, Fredrik Liedberg, Olle Melander, Karin Jirström, et al.
(2022) Scientific Reports, 12
Journal article

ANGPTL7, a therapeutic target for increased intraocular pressure and glaucoma

K. Praveen, O. Melander, Giovanni Coppola
(2022) Communications Biology, 5
Journal article

Mild-to-Moderate Kidney Dysfunction and Cardiovascular Disease: Observational and Mendelian Randomization Analyses

L. Gaziano, G. Engström, O. Melander, Emanuele Di Angelantonio
(2022) Circulation, 146 p.1507-1517
Journal article

Genetic variation of the blood coagulation regulator tissue factor pathway inhibitor and venous thromboembolism among middle-aged and older adults: A population-based cohort study

E. Manderstedt, J. Elf, P.J. Svensson, G. Engström, O. Melander, et al.
(2022) Research and practice in thrombosis and haemostasis, 6
Journal article (letter)

Rare coding variants in 35 genes associate with circulating lipid levels—A multi-ancestry analysis of 170,000 exomes

George Hindy, Leif Groop, Valeriya Lyssenko, Olle Melander, Peter M Nilsson, et al.
(2022) American Journal of Human Genetics, 109 p.81-96
Journal article

Stroke genetics informs drug discovery and risk prediction across ancestries

Aniket Mishra, Stephanie Debette
(2022) Nature, 611 p.115-123
Journal article

Investigation of possible underlying mechanisms behind water-induced glucose reduction in adults with high copeptin

Sofia Enhörning, Tiphaine Vanhaecke, Alberto Dolci, Erica T. Perrier, Olle Melander
(2021) Scientific Reports, 11
Journal article

Metabolic factors and the risk of Dupuytren’s disease : data from 30,000 individuals followed for over 20 years

Mattias Rydberg, Malin Zimmerman, Jin Persson Löfgren, Anders Gottsäter, Peter M. Nilsson, et al.
(2021) Scientific Reports, 11
Journal article

Amino acids predict prognosis in patients with acute dyspnea

Karolin Wiklund, Klas Gränsbo, Peter Almgren, Marjaneh Peyman, Lena Tegnér, et al.
(2021) BMC Emergency Medicine, 21
Journal article

Growth differentiation factor-15 and incident chronic kidney disease : a population-based cohort study

Xue Bao, Biao Xu, Yan Borné, Marju Orho-Melander, Olle Melander, et al.
(2021) BMC Nephrology, 22
Journal article

Association of thyroid function with blood pressure and cardiovascular disease : A mendelian randomization

Alice Giontella, Luca A. Lotta, John D. Overton, Aris Baras, Andrea Sartorio, et al.
(2021) Journal of Personalized Medicine, 11
Journal article

Comparison of risk factors for ischemic stroke and coronary events in a population-based cohort

Iram Faqir Muhammad, Yan Borné, Suneela Zaigham, Martin Söderholm, Linda Johnson, et al.
(2021) BMC Cardiovascular Disorders, 21
Journal article

Effect of Monoclonal Antibody Blockade of Long Fragment Neurotensin on Weight Loss, Behavior, and Metabolic Traits After High-Fat Diet Induced Obesity

Zherui Wu, Nicolas Stadler, Amazigh Abbaci, Jin Liu, Agnès Boullier, et al.
(2021) Frontiers in Endocrinology, 12
Journal article

Proteomic and Metabolomic Characterization of Metabolically Healthy Obesity: : A Descriptive Study from a Swedish Cohort

Johan Korduner, Peter M Nilsson, Olle Melander, Mathias J. Gerl, Gunnar Engström, et al.
(2021) Journal of Obesity, 2021
Journal article

An insulin resistance score improved diabetes risk assessment in the malmö prevention project—a longitudinal population-based study of older europeans

Dov Shiffman, Judy Z. Louie, James B. Meigs, James J. Devlin, Michael J. McPhaul, et al.
(2021) Diabetes Care, 44 p.186-187
Journal article (letter)

Rare, Damaging DNA Variants in CORIN and Risk of Coronary Artery Disease : Insights From Functional Genomics and Large-Scale Sequencing Analyses

Minxian Wang, Vivian S. Lee-Kim, Deepak S. Atri, Nadine H. Elowe, John Yu, et al.
(2021) Circulation. Genomic and precision medicine, 14
Journal article

Thrombotic Risk Determined by STAB 2 Variants in a Population-Based Cohort Study

Eric Manderstedt, Christer Halldén, Christina Lind-Halldén, Johan Elf, Peter J. Svensson, et al.
(2021) Circulation. Genomic and precision medicine, 14
Journal article (letter)

Translating polygenic risk scores for clinical use by estimating the confidence bounds of risk prediction

Jiangming Sun, Yunpeng Wang, Lasse Folkersen, Yan Borné, Inge Amlien, et al.
(2021) Nature Communications, 12 p.5276-5276
Journal article

A new pipeline for the normalization and pooling of metabolomics data

Vivian Viallon, Mathilde His, Sabina Rinaldi, Marie Breeur, Audrey Gicquiau, et al.
(2021) Metabolites, 11
Journal article

Sequencing of 640,000 exomes identifies GPR75 variants associated with protection from obesity

Parsa Akbari, Ankit Gilani, Olukayode Sosina, Jack A. Kosmicki, Lori Khrimian, et al.
(2021) Science, 373
Journal article

Vasoactive Biomarkers Associated With Long-Term Incidence of Symptomatic Peripheral Arterial Disease and Mortality

Ardwan Dakhel, Gunnar Engström, Olle Melander, Stefan Acosta, Shahab Fatemi, et al.
(2021) Angiology, 72 p.550-555
Journal article

Copeptin as a predictive marker of incident heart failure

Fredrika Schill, Simon Timpka, Peter M Nilsson, Olle Melander, Sofia Enhörning
(2021) ESC Heart Failure, 8 p.3180-3188
Journal article

Cellular dehydration acutely degrades mood mainly in women : A counterbalanced, crossover trial

Hyun Gyu Suh, Harris R. Lieberman, Lisa T. Jansen, Abigail T. Colburn, J. D. Adams, et al.
(2021) British Journal of Nutrition, 125 p.1092-1100
Journal article

Low risk patients with acute atrial fibrillation and elevated high-sensitivity troponin do not have increased incidence of pathological stress tests

Johan Thelin, Sofia Gerward, Olle Melander
(2021) Scandinavian cardiovascular journal : SCJ, 55 p.259-263
Journal article

Dietary Data in the Malmö Offspring Study : Reproducibility, Method Comparison and Validation against Objective Biomarkers

Sophie Hellstrand, Filip Ottosson, Einar Smith, Louise Brunkwall, Stina Ramne, et al.
(2021) Nutrients, 13
Journal article

Clustering of blood cell count abnormalities and future risk of death

Giuseppe Patti, Veronica Lio, Giuseppe Di Martino, Fabrizio Ricci, Giulia Renda, et al.
(2021) European Journal of Clinical Investigation, 51
Journal article

Circulating levels of growth hormone in postural orthostatic tachycardia syndrome

Madeleine Johansson, Fabrizio Ricci, Janin Schulte, Margaretha Persson, Olle Melander, et al.
(2021) Scientific Reports, 11
Journal article

Replication study reveals miR-483-5p as an important target in prevention of cardiometabolic disease

Widet Gallo, Filip Ottosson, Cecilia Kennbäck, Amra Jujic, Jonathan LS Esguerra, et al.
(2021) BMC Cardiovascular Disorders, 21
Journal article

Comprehensive functional annotation of susceptibility variants identifies genetic heterogeneity between lung adenocarcinoma and squamous cell carcinoma

Na Qin, Yuancheng Li, Cheng Wang, Meng Zhu, Juncheng Dai, et al.
(2021) Frontiers of Medicine, 15 p.275-291
Journal article

Genome-wide association meta-analysis identifies pleiotropic risk loci for aerodigestive squamous cell cancers

Corina Lesseur, Aida Ferreiro-Iglesias, James D McKay, Yohan Bossé, Mattias Johansson, et al.
(2021) PLoS Genetics, 17
Journal article

Plasma Protein Profile of Carotid Artery Atherosclerosis and Atherosclerotic Outcomes : Meta-Analyses and Mendelian Randomization Analyses

Lars Lind, Bruna Gigante, Yan Borné, Tobias Feldreich, Jerzy Leppert, et al.
(2021) Arteriosclerosis, Thrombosis, and Vascular Biology, 41
Journal article

Proteomic profiling reveals novel biomarkers and pathways in yype 2 diabetes risk

Debby Ngo, Mark D Benson, Jonathan Z Long, Zsu-Zsu Chen, Ruiqi Wang, et al.
(2021) JCI Insight, 6
Journal article

Circulating Vimentin Is Associated With Future Incidence of Stroke in a Population-Based Cohort Study

Jun Xiao, Liangwan Chen, Olle Melander, Marju Orho-Melander, Jan Nilsson, et al.
(2021) Stroke: a journal of cerebral circulation, 52 p.937-944
Journal article

A plasma lipid signature predicts incident coronary artery disease

Filip Ottosson, Payam Emami Khoonsari, Mathias J. Gerl, Kai Simons, Olle Melander, et al.
(2021) International Journal of Cardiology, 331
Journal article

Comparison of cardiovascular disease and cancer prevalence between Mediterranean and north European middle-aged populations (The Cilento on Ageing Outcomes Study and The Malmö Offspring Study)

Olle Melander, Paola Antonini, Filip Ottosson, Louise Brunkwall, Widet Gallo, et al.
(2021) Internal and Emergency Medicine, 16 p.1567-1572
Journal article

Bioreactance and Apelin in the Management of Severe Hyponatremia

Karin Olsson, Magnus Löndahl, Olle Melander, Per Katzman
(2021) Open Journal of Emergency Medicine , p.1-10
Journal article

Pro B-type Natriuretic Peptide and Midregional Proadrenomedullin are Associated with Incident Carotid Stenosis During Long Term Follow-up

Shahab Fatemi, Stefan Acosta, Moncef Zarrouk, Gunnar Engström, Olle Melander, et al.
(2021) Journal of Stroke and Cerebrovascular Diseases, 30
Journal article

Glucose-Dependent Insulinotropic Peptide in the High-Normal Range Is Associated With Increased Carotid Intima-Media Thickness

Amra Jujić, Peter M Nilsson, Naeimeh Atabaki-Pasdar, Anna Dieden, Tiinamaija Tuomi, et al.
(2021) Diabetes Care, 44 p.224-230
Journal article

The associations between red cell distribution width and plasma proteins in a general population

Jingxue Pan, Yan Borné, Marju Orho-Melander, Jan Nilsson, Olle Melander, et al.
(2021) Clinical Proteomics, 18
Journal article

A Journey through the Early Evidence Linking Hydration to Metabolic Health

Tiphaine Vanhaecke, Erica T. Perrier, Olle Melander
(2021) Annals of Nutrition and Metabolism, 76 p.4-9
Journal article

The copy number variation and stroke (CaNVAS) risk and outcome study

John W Cole, Taiwo Adigun, Rufus Akinyemi, Onoja Matthew Akpa, Steven Bell, et al.
(2021) PLoS ONE, 16
Journal article

Socioeconomic and clinical predictors of mortality in patients with acute dyspnea

Torgny Wessman, Rafid Tofik, Thoralph Ruge, Olle Melander
(2021) Open Access Emergency Medicine, 13 p.107-116
Journal article

Methodological considerations for identifying multiple plasma proteins associated with all-cause mortality in a population-based prospective cohort

Isabel Drake, George Hindy, Peter Almgren, Gunnar Engström, Jan Nilsson, et al.
(2021) Scientific Reports, 11
Journal article

Causal effect of adiposity measures on blood pressure traits in 2 urban swedish cohorts : A mendelian randomization study

Alice Giontella, Luca A. Lotta, John D. Overton, Aris Baras, Pietro Minuz, et al.
(2021) Journal of the American Heart Association, 10
Journal article

Novel insights into peptide amidation and amidating activity in the human circulation

Paul Kaufmann, Andreas Bergmann, Olle Melander
(2021) Scientific Reports, 11
Journal article

Association of Sleep Duration with All- And Major-Cause Mortality among Adults in Japan, China, Singapore, and Korea

Thomas Svensson, Eiko Saito, Akiko Kishi Svensson, Olle Melander, Marju Orho-Melander, et al.
(2021) JAMA Network Open, 4
Journal article

Plant foods, dietary fibre and risk of ischaemic heart disease in the European prospective investigation into cancer and nutrition (EPIC) cohort

Aurora Perez-Cornago, Francesca L Crowe, Paul N Appleby, Kathryn E Bradbury, Angela M Wood, et al.
(2021) International Journal of Epidemiology, 50 p.212-222
Journal article

Growth differentiation factor-15 is a biomarker for all-cause mortality but less evident for cardiovascular outcomes : A prospective study

Xue Bao, Yan Borné, Biao Xu, Marju Orho-Melander, Jan Nilsson, et al.
(2021) American Heart Journal, 234 p.81-89
Journal article

Circulating pro-neurotensin levels predict bodyweight gain and metabolic alterations in children

Ilaria Barchetta, Laura Bertoccini, Federica Sentinelli, Diego Bailetti, Giacomo Marini, et al.
(2021) Nutrition, Metabolism and Cardiovascular Diseases, 31 p.902-910
Journal article

Association of Circulating Monocyte Chemoattractant Protein-1 Levels with Cardiovascular Mortality : A Meta-analysis of Population-Based Studies

Marios K. Georgakis, James A. De Lemos, Colby Ayers, Biqi Wang, Harry Björkbacka, et al.
(2021) JAMA Cardiology, 6 p.587-592
Journal article

Integration of multiomic annotation data to prioritize and characterize inflammation and immune-related risk variants in squamous cell lung cancer

Ryan Sun, Olle Melander, Hans Brunnström, Xihong Lin
(2021) Genetic Epidemiology, 45 p.99-114
Journal article

The Malmö Offspring Study (MOS) : design, methods and first results

Louise Brunkwall, Daniel Jönsson, Ulrika Ericson, Sophie Hellstrand, Cecilia Kennbäck, et al.
(2021) European Journal of Epidemiology, 36 p.103-116
Journal article

Dietary fatty acids, macronutrient substitutions, food sources and incidence of coronary heart disease: Findings from the EPIC-CVD case-cohort study across nine european countries

M. Steur, Ulrika Ericson, Olle Melander, Nita G. Forouhi
(2021) Journal of the American Heart Association, 10
Journal article

Pro-Enkephalin and its association with renal function in Middle Eastern immigrants and native Swedes

Christopher Nilsson, Anders Christensson, Peter M. Nilsson, Olle Melander, Louise Bennet
(2021) Scandinavian Journal of Clinical and Laboratory Investigation, 81 p.573-578
Journal article

The association between bmi and 90-day mortality in patients with and without diabetes seeking care at the emergency department

Per Wändell, Axel C. Carlsson, Anders Larsson, Olle Melander, Torgny Wessman, et al.
(2021) Upsala Journal of Medical Sciences, 126
Journal article

Elevated circulating follistatin associates with an increased risk of type 2 diabetes

Chuanyan Wu, Yan Borné, Rui Gao, Maykel López Rodriguez, William C Roell, et al.
(2021) Nature Communications, 12 p.1-10
Journal article

Copeptin as a marker of atherosclerosis and arteriosclerosis

Fredrika Schill, Margaretha Persson, Gunnar Engström, Olle Melander, Sofia Enhörning
(2021) Atherosclerosis, 338 p.64-68
Journal article

Causal relationships between body mass index, smoking and lung cancer : Univariable and multivariable Mendelian randomization

Wen Zhou, Geoffrey Liu, Rayjean J. Hung, Philip C. Haycock, Melinda C. Aldrich, et al.
(2021) International Journal of Cancer, 148 p.1077-1086
Journal article

The genomics of heart failure : design and rationale of the HERMES consortium

R. Thomas Lumbers, Sonia Shah, Honghuang Lin, Tomasz Czuba, Albert Henry, et al.
(2021) ESC Heart Failure, 8 p.5531-5541
Journal article

Genome-wide association analyses highlight etiological differences underlying newly defined subtypes of diabetes

Dina Mansour Aly, Om Prakash Dwivedi, Rashmi B Prasad, Annemari Käräjämäki, Rebecka Hjort, et al.
(2021) Nature Genetics, 53 p.1534-1542
Journal article

Impact of genetic risk score on the association between male childlessness and cardiovascular disease and mortality

Angel Elenkov, Olle Melander, Peter M Nilsson, He Zhang, Aleksander Giwercman
(2021) Scientific Reports, 11 p.1-10
Journal article

Hyperglycaemia-associated Caspase-3 predicts diabetes and coronary artery disease events

Jiangming Sun, Pratibha Singh, Johan Österlund, Marju Orho-Melander, Olle Melander, et al.
(2021) Journal of Internal Medicine, 290 p.855-865
Journal article

Plasma calprotectin in the emergency department : a potential clinical biomarker for patients with infectious diseases

Martin Wollmer, Per Wändell, Mari Rosenqvist, Anders Larsson, Olle Melander, et al.
(2021) Scandinavian Journal of Clinical and Laboratory Investigation, 81 p.593-597
Journal article

Hydration for health hypothesis : a narrative review of supporting evidence

Erica T. Perrier, Lawrence E. Armstrong, Jeanne H. Bottin, William F. Clark, Alberto Dolci, et al.
(2021) European Journal of Nutrition, 60 p.1167-1180
Journal article review

Genome-wide association study identifies novel single nucleotide polymorphisms having age-specific effect on prostate-specific antigen levels

Weiqiang Li, Mesude Bicak, Daniel D. Sjoberg, Emily Vertosick, Anders Dahlin, et al.
(2020) Prostate, 80 p.1405-1412
Journal article

The gut microbiota-related metabolite phenylacetylglutamine associates with increased risk of incident coronary artery disease

Filip Ottosson, Louise Brunkwall, Einar Smith, Marju Orho-Melander, Peter M. Nilsson, et al.
(2020) Journal of Hypertension, 38 p.2427-2434
Journal article

NT-proBNP and metabolic risk factors in a bi-ethnic cohort : the Ambulatory Blood Pressure in African prospective cohort study

Amra Jujić, Olle Melander, Peter M Nilsson, Leoné Malan, Artur Fedorowski, et al.
(2020) Cardiovascular Journal of Africa, 31 p.291-297
Journal article

Association of coronary calcium score with endothelial dysfunction and arterial stiffness

Kristina Torngren, Rebecca Rylance, Jonas Björk, Gunnar Engström, Sophia Frantz, et al.
(2020) Atherosclerosis, 313 p.70-75
Journal article

Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline

Mathias Gorski, Iris M. Heid
(2020) Kidney International, 99 p.926-939
Journal article

Proteomic exploration of common pathophysiological pathways in diabetes and cardiovascular disease

John Molvin, Amra Jujić, Olle Melander, Manan Pareek, Lennart Råstam, et al.
(2020) ESC Heart Failure
Journal article

The association of single nucleotide polymorphisms (SNPs) with breast density and breast cancer survival : the Malmö Diet and Cancer Study

Hanna Sartor, Jasmine Brandt, Felix Grassmann, Mikael Eriksson, Kamila Czene, et al.
(2020) Acta Radiologica, 61 p.1326-1334
Journal article

High body mass index is associated with increased risk for osteoarthritis of the first carpometacarpal joint during more than 30 years of follow-up

Mattias Rydberg, Lars B Dahlin, Anders Gottsäter, Peter M Nilsson, Olle Melander, et al.
(2020) RMD Open, 6
Journal article

TNFR1 is associated with short-term mortality in patients with diabetes and acute dyspnea seeking care at the emergency department

P. Wändell, A. C. Carlsson, A. Larsson, O. Melander, T. Wessman, et al.
(2020) Acta Diabetologica, 57 p.1145-1150
Journal article

Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals

Lasse Folkersen, Stefan Gustafsson, Qin Wang, Daniel Hvidberg Hansen, Åsa K Hedman, et al.
(2020) Nature Metabolism, 2 p.1135-1148
Journal article

Novel biomarkers for prediction of outcome in hip fracture patients—An exploratory study

Magnus H. Jonsson, Ami Hommel, Lizbet Todorova, Olle Melander, Peter Bentzer
(2020) Acta Anaesthesiologica Scandinavica, 64 p.920-927
Journal article

Circulating protein biomarkers predict incident hypertensive heart failure independently of N-terminal pro-B-type natriuretic peptide levels

Celine Fernandez, Jaana Rysä, Kristoffer Ström, Jan Nilsson, Gunnar Engström, et al.
(2020) ESC Heart Failure, 7 p.1891-1899
Journal article

Evaluating drug targets through human loss-of-function genetic variation

Eric Vallabh Minikel, Daniel G MacArthur
(2020) Nature, 581 p.459-464
Journal article

Transcript expression-aware annotation improves rare variant interpretation

Beryl B. Cummings, Daniel G MacArthur
(2020) Nature, 581 p.452-458
Journal article

A structural variation reference for medical and population genetics

Ryan Collins, Michael E Talkowski
(2020) Nature, 581 p.444-451
Journal article

The mutational constraint spectrum quantified from variation in 141,456 humans

Konrad J. Karczewski, Daniel G MacArthur
(2020) Nature, 581 p.434-443
Journal article

Genome-wide association study of INDELs identified four novel susceptibility loci associated with lung cancer risk

Juncheng Dai, Mingtao Huang, Christopher I. Amos, Rayjean J. Hung, Adonina Tardon, et al.
(2020) International Journal of Cancer, 146 p.2855-2864
Journal article

Blood pressure and risk of cancer in the European Prospective Investigation into Cancer and Nutrition

Sofia Christakoudi, Artemisia Kakourou, Georgios Markozannes, Ioanna Tzoulaki, Elisabete Weiderpass, et al.
(2020) International Journal of Cancer, 146 p.2680-2693
Journal article

High circulating levels of midregional proenkephalin A predict vascular dementia : a population-based prospective study

H Holm, K Nägga, E D Nilsson, F Ricci, O Melander, et al.
(2020) Scientific Reports, 10
Journal article

Glucose-dependent insulinotropic peptide and risk of cardiovascular events and mortality : a prospective study

Amra Jujić, Naeimeh Atabaki-Pasdar, Peter M Nilsson, Peter Almgren, Liisa Hakaste, et al.
(2020) Diabetologia, 63 p.1043-1054
Journal article

Gamma-glutamyltransferase, arterial remodeling and prehypertension in a healthy population at low cardiometabolic risk

Michaela Kozakova, Amalia Gastaldelli, Carmela Morizzo, Kurt Højlund, Peter M Nilsson, et al.
(2020) Journal of Human Hypertension
Journal article

Lipoprotein Particle Predictors of Arterial Stiffness after 17 Years of Follow Up : The Malmö Diet and Cancer Study

Jacob Hartz, Ronald M. Krauss, Mikael Gottsäter, Olle Melander, Peter Nilsson, et al.
(2020) International Journal of Vascular Medicine, 2020
Journal article

Proteomic analysis reveals sex-specific biomarker signature in postural orthostatic tachycardia syndrome

Jasmina Medic Spahic, Fabrizio Ricci, Nay Aung, Erik Hallengren, Jonas Axelsson, et al.
(2020) BMC Cardiovascular Disorders, 20
Journal article

Reply to : Risk factors associated with cardiac arrest

Marcus Andreas Ohlsson, Olle Melander
(2020) Resuscitation, 151 p.217-217
Journal article (letter)

Transcriptome-wide association study reveals candidate causal genes for lung cancer

Yohan Bossé, Zhonglin Li, Jun Xia, Venkata Manem, Robert Carreras-Torres, et al.
(2020) International Journal of Cancer, 146 p.1862-1878
Journal article

Diabetes mellitus as a risk factor for compression neuropathy: a longitudinal cohort study from southern Sweden

Mattias Rydberg, Malin Zimmerman, Anders Gottsäter, Peter M Nilsson, Olle Melander, et al.
(2020) BMJ open diabetes research & care, 8
Journal article

Exploration of pathophysiological pathways for incident atrial fibrillation using a multiplex proteomic chip

John Molvin, Amra Jujic, Olle Melander, Manan Pareek, Lennart Råstam, et al.
(2020) Open Heart, 7
Journal article

Periodontal disease is associated with carotid plaque area: the Malmö Offspring Dental Study (MODS).

D. Jönsson, M. Orho-Melander, R. T. Demmer, G. Engström, O. Melander, et al.
(2020) Journal of Internal Medicine, 287 p.301-309
Journal article

Metabolomic Signature of Early Vascular Aging (EVA) in Hypertension

Katarzyna Polonis, Renata Wawrzyniak, Emilia Daghir-Wojtkowiak, Anna Szyndler, Marzena Chrostowska, et al.
(2020) Frontiers in Molecular Biosciences, 7
Journal article

Plasma kidney injury molecule-1 (p-KIM-1) levels and deterioration of kidney function over 16 years

Christina-Alexandra Schulz, Gunnar Engström, Jan Nilsson, Peter Almgren, Marinka Petkovic, et al.
(2020) Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 35 p.265-273
Journal article

Beta-blocker therapy and risk of vascular dementia : A population-based prospective study

H Holm, F Ricci, G Di Martino, E Bachus, E D Nilsson, et al.
(2020) Vascular Pharmacology, 125-126
Journal article

Plasma Lipidome and Prediction of Type 2 Diabetes in the Population-Based Malmö Diet and Cancer Cohort

Céline Fernandez, Michal A. Surma, Christian Klose, Mathias J. Gerl, Filip Ottosson, et al.
(2020) Diabetes Care, 43 p.366-373
Journal article

Response to Letter to the Editor : "Water Supplementation Reduces Copeptin and Plasma Glucose in Adults with High Copeptin: The H2O Metabolism Pilot Study"

Sofia Enhörning, Olle Melander
(2020) The Journal of clinical endocrinology and metabolism, 105
Journal article (comment)

Endostatin predicts mortality in patients with acute dyspnea – A cohort study of patients seeking care in emergency departments

A. C. Carlsson, T. Wessman, A. Larsson, G. Leijonberg, R. Tofik, et al.
(2020) Clinical Biochemistry, 75 p.35-39
Journal article

Risk prediction of future cardiac arrest by evaluation of a genetic risk score alone and in combination with traditional risk factors

Marcus Andreas Ohlsson, Linn Maria Anna Kennedy, Tord Juhlin, Olle Melander
(2020) Resuscitation, 146 p.74-79
Journal article

Orthostatic hypotension and novel blood pressure associated gene variants in older adults : data from the TILDA Study

Eamon Laird, Aisling M O'Halloran, Artur Fedorowski, Olle Melander, Ann Hever, et al.
(2020) Journals of Gerontology. Series A: Biological Sciences & Medical Sciences, 75 p.2074-2080
Journal article

Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure

Sonia Shah, Peter Almgren, Gunnar Engström, Olle Melander, Gustav Smith, et al.
(2020) Nature Communications, 11
Journal article

Genetic Discrimination Between LADA and Childhood-Onset Type 1 Diabetes Within the MHC

Rajashree Mishra, Mikael Åkerlund, Diana L. Cousminer, Emma Ahlqvist, Jonathan P. Bradfield, et al.
(2020) Diabetes Care, 43 p.418-425
Journal article

Genome-wide Association Analysis in Humans Links Nucleotide Metabolism to Leukocyte Telomere Length

Chen Li, Markus Perola, Paul Franks, Johan Gunnar Eriksson, Olle Melander, et al.
(2020) American Journal of Human Genetics, 106 p.389-404
Journal article

Plasma metabolites associate with all-cause mortality in individuals with type 2 diabetes

Filip Ottosson, Einar Smith, Céline Fernandez, Olle Melander
(2020) Metabolites, 10
Journal article

Blood pressure and bladder cancer risk in men by use of survival analysis and in interaction with NAT2 genotype, and by Mendelian randomization analysis

Stanley Teleka, George Hindy, Isabel Drake, Alaitz Poveda, Olle Melander, et al.
(2020) PLoS ONE, 15
Journal article

A new efficient method to detect genetic interactions for lung cancer GWAS

Jennifer Luyapan, Xuemei Ji, Siting Li, Xiangjun Xiao, Dakai Zhu, et al.
(2020) BMC Medical Genomics, 13
Journal article

Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals

Praveen Surendran, Cristiano Fava, Olle Melander, Marju Orho-Melander, Alaitz Poveda, et al.
(2020) Nature Genetics, 52 p.1314-1332
Journal article

Altered Acylcarnitine Metabolism Is Associated With an Increased Risk of Atrial Fibrillation

Einar Smith, Celine Fernandez, Olle Melander, Filip Ottosson
(2020) Journal of the American Heart Association, 9 p.016737-016737
Journal article

Circulating bioactive adrenomedullin as a marker of sepsis, septic shock and critical illness

Oscar H.M. Lundberg, Maria Lengquist, Martin Spångfors, Martin Annborn, Deborah Bergmann, et al.
(2020) Critical Care, 24
Journal article

In adults with obesity, copeptin is linked with BMI but is not associated with long-term exposure to cortisol and cortisone

Eline S. van der Valk, Bibian van der Voorn, Anand M. Iyer, Sjoerd A.A. van den Berg, Mesut Savas, et al.
(2020) European Journal of Endocrinology, 183 p.669-676
Journal article

Evidence for a protective role of placental growth factor in cardiovascular disease

Yihong Chen, Anna Hultgårdh Nilsson, Isabel Goncalves, Andreas Edsfeldt, Gunnar Engström, et al.
(2020) Science Translational Medicine, 12
Journal article

The plasma protein profile and cardiovascular risk differ between intima-media thickness of the common carotid artery and the bulb : A meta-analysis and a longitudinal evaluation

Lars Lind, Bruna Gigante, Yan Borne, Anders Mälarstig, Johan Sundström, et al.
(2020) Atherosclerosis, 295 p.25-30
Journal article

The effect of LRRK2 loss-of-function variants in humans

Nicola Whiffin, Leif Groop, Olle Melander, Peter M. Nilsson, Daniel G MacArthur
(2020) Nature Medicine , p.869-877
Journal article

The authors reply

Mari Rosenqvist, Maria Bengtsson-Toni, Johan Tham, Peter Lanbeck, Olle Melander, et al.
(2020) Critical Care Medicine, 48 p.633-634
Journal article (letter)

Clinical Evaluation of the Polygenetic Background of Blood Pressure in the Population-Based Setting

Alice Giontella, Marketa Sjögren, Luca A. Lotta, John D. Overton, Aris Baras, et al.
(2020) Hypertension , p.169-177
Journal article

Magnitude of rise in proneurotensin is related to amount of triglyceride appearance in blood after standardized oral intake of both saturated and unsaturated fat

Ayesha Fawad, Celine Fernandez, Andreas Bergmann, Joachim Struck, Peter M. Nilsson, et al.
(2020) Lipids in Health and Disease, 19
Journal article

Genome-Wide Polygenic Score, Clinical Risk Factors, and Long-Term Trajectories of Coronary Artery Disease

George Hindy, Krishna G. Aragam, Kenney Ng, Mark Chaffin, Luca A. Lotta, et al.
(2020) Arteriosclerosis, Thrombosis, and Vascular Biology, 40 p.2738-2746
Journal article

Characterising the loss-of-function impact of 5’ untranslated region variants in 15,708 individuals

Nicola Whiffin, Leif Groop, C Haiman, Olle Melander, Peter M Nilsson, et al.
(2020) Nature Communications, 11
Journal article

Landscape of multi-nucleotide variants in 125,748 human exomes and 15,708 genomes

Qingbo Wang, Leif Groop, C Haiman, Olle Melander, Peter M Nilsson, et al.
(2020) Nature Communications, 11
Journal article

Protein-altering germline mutations implicate novel genes related to lung cancer development

Xuemei Ji, Hans Brunnström, Jonas Manjer, Olle Melander, Kim Overvad, et al.
(2020) Nature Communications, 11
Journal article

Improved Outcomes After Regional Implementation of Sepsis Alert : A Novel Triage Model

Mari Rosenqvist, Maria Bengtsson-Toni, Johan Tham, Peter Lanbeck, Olle Melander, et al.
(2020) Critical Care Medicine, 48 p.484-490
Journal article

Association of TIM-1 (T-Cell Immunoglobulin and Mucin Domain 1) With Incidence of Stroke

Lu Song, Jiangming Sun, Martin Söderholm, Olle Melander, Marju Orho-Melander, et al.
(2020) Arteriosclerosis, Thrombosis, and Vascular Biology, 40 p.1777-1786
Journal article

Association Analysis of Driver Gene-Related Genetic Variants Identified Novel Lung Cancer Susceptibility Loci with 20,871 Lung Cancer Cases and 15,971 Controls

Yuzhuo Wang, Olga Y. Gorlova, Ivan P. Gorlov, Meng Zhu, Juncheng Dai, et al.
(2020) Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 29 p.1423-1429
Journal article

Discovery of 318 new risk loci for type 2 diabetes and related vascular outcomes among 1.4 million participants in a multi-ancestry meta-analysis

Marijana Vujkovic, Olle Melander, Danish Saleheen
(2020) Nature Genetics, 52 p.680-691
Journal article

The association between plasma proneurotensin and glucose regulation is modified by country of birth

A. Fawad, P. M. Nilsson, J. Struck, A. Bergmann, O. Melander, et al.
(2019) Scientific Reports, 9
Journal article

Proenkephalin a 119-159 (penKid) - a novel biomarker for acute kidney injury in sepsis : an observational study

Mari Rosenqvist, Kevin Bronton, Oliver Hartmann, Andreas Bergmann, Joachim Struck, et al.
(2019) BMC Emergency Medicine, 19
Journal article

The associations of self-rated health with cardiovascular risk proteins : A proteomics approach

Xue Bao, Yan Borné, Songjiang Yin, Kaijun Niu, Marju Orho-Melander, et al.
(2019) Clinical Proteomics, 16
Journal article

Yogic Breathing and Mindfulness as Stress-Coping Mediate Positive Health Outcomes of Yoga

Una Tellhed, Daiva Daukantaité, Rachel Maddux, Thomas Svensson, Olle Melander
(2019) Mindfulness, 10 p.2703-2715
Journal article

Platelet Indices and Risk of Death and Cardiovascular Events : Results from a Large Population-Based Cohort Study

Giuseppe Patti, Giuseppe Di Martino, Fabrizio Ricci, Giulia Renda, Sabina Gallina, et al.
(2019) Thrombosis and Haemostasis, 119 p.1773-1784
Journal article

Cardiovascular Autonomic Dysfunction Is the Most Common Cause of Syncope in Paced Patients

Ekrem Yasa, Fabrizio Ricci, Hannes Holm, Torbjörn Persson, Olle Melander, et al.
(2019) Frontiers in Cardiovascular Medicine, 6
Journal article

Polygenetic risk for coronary artery disease increases hospitalization burden and mortality

Marketa Sjögren, Peter Almgren, Olle Melander
(2019) IJC Heart and Vasculature, 24
Journal article

Selenoprotein P Deficiency and Risk of Mortality and Rehospitalization in Acute Heart Failure

Amra Jujić, Olle Melander, Andreas Bergmann, Oliver Hartmann, Peter M Nilsson, et al.
(2019) Journal of the American College of Cardiology, 74 p.1009-1011
Journal article (letter)

CHA2DS2VASc score and adverse outcomes in middle-aged individuals without atrial fibrillation

Giulia Renda, Fabrizio Ricci, Giuseppe Patti, Nay Aung, Steffen E Petersen, et al.
(2019) European Journal of Preventive Cardiology, 26 p.1987-1997
Journal article

Circulating HER2/ErbB2 Levels Are Associated With Increased Incidence of Diabetes : A Population-Based Cohort Study

Iram Faqir Muhammad, Yan Borné, Xue Bao, Olle Melander, Marju Orho-Melander, et al.
(2019) Diabetes Care, 42 p.1582-1588
Journal article

Association of menopausal characteristics and risk of coronary heart disease : A pan-European case-cohort analysis

Veerle Dam, Yvonne T. Van Der Schouw, N. Charlotte Onland-Moret, Rolf H.H. Groenwold, Sanne A.E. Peters, et al.
(2019) International Journal of Epidemiology, 48 p.1275-1285
Journal article

Seleno protein-P deficiency predicts cardiovascular disease and death

Lutz Schomburg, Marju Orho-Melander, Joachim Struck, Andreas Bergmann, Olle Melander
(2019) Nutrients, 11
Journal article

Cardiovascular biomarkers predict post-discharge re-hospitalization risk and mortality among Swedish heart failure patients

John Molvin, Amra Jujic, Erasmus Bachus, Widet Gallo, Gordana Tasevska-Dinevska, et al.
(2019) ESC Heart Failure, 6 p.992-999
Journal article

Bioactive adrenomedullin, proenkephalin A and clinical outcomes in an acute heart failure setting

John Molvin, Amra Jujic, Silvia Navarin, Olle Melander, Giada Zoccoli, et al.
(2019) Open Heart, 6
Journal article

The co-predictive value of a cardiovascular score for CV outcomes in diabetic patients with no atrial fibrillation

Giuseppe Patti, Alessandro Sticchi, Vincenzo Pasceri, Fabrizio Ricci, Giulia Renda, et al.
(2019) Diabetes/Metabolism Research and Reviews, 35 p.1-9
Journal article

Impact of Cardiovascular Neurohormones on Onset of Vasovagal Syncope Induced by Head-up Tilt.

Parisa Torabi, Fabrizio Ricci, Viktor Hamrefors, Olle Melander, Richard Sutton, et al.
(2019) Journal of the American Heart Association, 8
Journal article

Water Supplementation Reduces Copeptin and Plasma Glucose in Adults With High Copeptin : The H2O Metabolism Pilot Study

Sofia Enhörning, Louise Brunkwall, Irina Tasevska, Ulrika Ericson, Jenny Persson Tholin, et al.
(2019) The Journal of clinical endocrinology and metabolism, 104 p.1917-1925
Journal article

Hypertonic Saline Infusion Acutely Degrades Mood in Healthy Volunteers (P23-014-19)

HyunGyu Suh, Harris Lieberman, Lisa Jansen, J D Adams, Adam Seal, et al.
(2019) Current Development in Nutrition, 3
Journal article

A catalog of genetic loci associated with kidney function from analyses of a million individuals

Matthias Wuttke, Peter Almgren, Cecilia M Lindgren, Olle Melander, Marju Orho-Melander, et al.
(2019) Nature Genetics, 51 p.957-972
Journal article

Genetic Predisposition for Renal Dysfunction and Incidence of CKD in the Malmö Diet and Cancer Study

Christina Alexandra Schulz, Gunnar Engström, Anders Christensson, Peter M. Nilsson, Olle Melander, et al.
(2019) Kidney International Reports, 4 p.1143-1151
Journal article

Biomarkers of blood cadmium and incidence of cardiovascular events in non-smokers : Results from a population-based proteomics study

Yan Borné, Björn Fagerberg, Gerd Sallsten, Bo Hedblad, Margaretha Persson, et al.
(2019) Clinical Proteomics, 16
Journal article

Skin autofluorescence as a measure of advanced glycation end product levels is associated with carotid atherosclerotic plaque burden in an elderly population

Amra Jujić, Gerd Östling, Margaretha Persson, Gunnar Engström, Peter M Nilsson, et al.
(2019) Diabetes & Vascular Disease Research, 16 p.466-473
Journal article

Elevated plasma copeptin levels identify the presence and severity of non-alcoholic fatty liver disease in obesity

Ilaria Barchetta, Sofia Enhörning, Flavia Agata Cimini, Danila Capoccia, Caterina Chiappetta, et al.
(2019) BMC Medicine, 17
Journal article

Lp-PLA ₂ activity and mass and CRP are associated with incident symptomatic peripheral arterial disease

Shahab Fatemi, Anders Gottsäter, Moncef Zarrouk, Gunnar Engström, Olle Melander, et al.
(2019) Scientific Reports, 9
Journal article

Proconvertase furin is down regulated in postural orthostatic tachycardia syndrome

Jasmina Medic Spahic, Fabrizio Ricci, Nay Aung, Jonas Axelsson, Olle Melander, et al.
(2019) Frontiers in Neuroscience, 13
Journal article

Increased mortality among acute respiratory distress patients from immigrant dense urban districts

Torgny Wessman, Rafid Tofik, Klas Gränsbo, Olle Melander
(2019) Open Access Emergency Medicine, 11 p.43-49
Journal article

Association of cardiovascular events and lipoprotein particle size : Development of a risk score based on functional data analysis

Charles M. Rowland, Dov Shiffman, Michael Caulfield, Veronica Garcia, Olle Melander, et al.
(2019) PLoS ONE, 14
Journal article

The early identification of disease progression in patients with suspected infection presenting to the emergency department : A multi-centre derivation and validation study

Kordo Saeed, Darius Cameron Wilson, Frank Bloos, Philipp Schuetz, Yuri Van Der Does, et al.
(2019) Critical Care, 23
Journal article

A novel rare CUBN variant and three additional genes identified in Europeans with and without diabetes : results from an exome-wide association study of albuminuria

Tarunveer S. Ahluwalia, Christina Alexandra Schulz, Johannes Waage, Tea Skaaby, Niina Sandholm, et al.
(2019) Diabetologia, 62 p.292-305
Journal article

Using a Targeted Proteomics Chip to Explore Pathophysiological Pathways for Incident Diabetes- The Malmö Preventive Project

John Molvin, Manan Pareek, Amra Jujic, Olle Melander, Lennart Råstam, et al.
(2019) Scientific Reports, 9
Journal article

A genetic risk score for hypertension is associated with risk of thoracic aortic aneurysm

A. Tagetti, S. Bonafini, T. Ohlsson, G. Engström, P. Almgren, et al.
(2019) Journal of Human Hypertension, 33 p.658-663
Journal article

Cardiometabolic Polygenic Risk Scores and Osteoarthritis Outcomes : A Mendelian Randomization Study Using Data From the Malmö Diet and Cancer Study and the UK Biobank

George Hindy, Kristina E. Åkesson, Olle Melander, Krishna G. Aragam, Mary E. Haas, et al.
(2019) Arthritis and Rheumatology, 71 p.925-934
Journal article

Plasma copeptin as a predictor of kidney disease

Sofia Enhörning, Anders Christensson, Olle Melander
(2019) Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 34 p.74-82
Journal article

Cardiovascular biomarkers and echocardiographic findings at rest and during graded hypovolemic stress in women with recurrent vasovagal syncope

Marcus Lindenberger, Arthur Fedorowski, Olle Melander, Widet Gallo, Jan Engvall, et al.
(2019) Journal of Cardiovascular Electrophysiology, 30 p.2936-2943
Journal article

Anti-ApoA-I IgG antibodies are not associated with carotid artery disease progression and first-time cardiovascular events in middle-aged individuals

J. O. Lagerstedt, J. Dalla-Riva, G. Marinkovic, R. Del Giudice, D. Engelbertsen, et al.
(2019) Journal of Internal Medicine, 285 p.49-58
Journal article

Effects of hydration on plasma copeptin, glycemia and gluco-regulatory hormones : a water intervention in humans

Sofia Enhörning, Irina Tasevska, Ronan Roussel, Nadine Bouby, Margaretha Persson, et al.
(2019) European Journal of Nutrition, 58 p.315-324
Journal article

Trans-ethnic association study of blood pressure determinants in over 750,000 individuals

Ayush Giri, Peter Almgren, Olle Melander, Adriana M. Hung, Todd L Edwards
(2019) Nature Genetics, 51 p.51-62
Journal article

Modulation of lung cancer cell plasticity and heterogeneity with the restoration of cisplatin sensitivity by neurotensin antibody

Zherui Wu, Ludovic Fournel, Nicolas Stadler, Jin Liu, Agnès Boullier, et al.
(2019) Cancer Letters, 444 p.147-161
Journal article

Genetic interaction analysis among oncogenesis-related genes revealed novel genes and networks in lung cancer development

Yafang Li, Hans Brunnström, Jonas Manjer, Olle Melander, Christopher I Amos
(2019) Oncotarget, 10 p.1760-1774
Journal article

High Plasma sRAGE (Soluble Receptor for Advanced Glycation End Products) Is Associated With Slower Carotid Intima-Media Thickness Progression and Lower Risk for First-Time Coronary Events and Mortality

Helena Grauen Larsen, Goran Marinkovic, Peter M. Nilsson, Jan Nilsson, Gunnar Engström, et al.
(2019) Arteriosclerosis, Thrombosis, and Vascular Biology, 39 p.925-933
Journal article

Cardiovascular biomarkers predict fragility fractures in older adults

Madeleine Johansson, Fabrizio Ricci, Giuseppe Di Martino, Cecilia Rogmark, Richard Sutton, et al.
(2019) Heart, 105 p.449-454
Journal article

Increased vascular endothelial growth factor D is associated with atrial fibrillation and ischaemic stroke

John Berntsson, J. Gustav Smith, Linda S.B. Johnson, Martin Söderholm, Yan Borné, et al.
(2019) Heart, 105 p.553-558
Journal article

Growth differentiation factor 15 is positively associated with incidence of diabetes mellitus : the Malmö Diet and Cancer–Cardiovascular Cohort

Xue Bao, Yan Borné, Iram Faqir Muhammad, Jan Nilsson, Lars Lind, et al.
(2019) Diabetologia, 62 p.78-86
Journal article

Effect of acute hypohydration on glycemic regulation in healthy adults : A randomized crossover trial

Harriet A. Carroll, Iain Templeman, Yung Chih Chen, Robert M. Edinburgh, Elaine K. Burch, et al.
(2019) Journal of Applied Physiology, 126 p.422-430
Journal article

Pacing therapy in the management of unexplained syncope : A tertiary care centre prospective study

Ekrem Yasa, Fabrizio Ricci, Hannes Holm, Torbjörn Persson, Olle Melander, et al.
(2019) Open Heart, 6
Journal article

C-peptide predicts all-cause and cardiovascular death in a cohort of individuals with newly diagnosed type 2 diabetes. The Skaraborg diabetes register

Miriam Pikkemaat, Tobias Andersson, Olle Melander, John Chalmers, Karin Rådholm, et al.
(2019) Diabetes Research and Clinical Practice, 150 p.174-183
Journal article

Midregional proadrenomedullin predicts reduced blood pressure and glucose elevation over time despite enhanced progression of obesity markers

Therese Ohlsson, Peter M. Nilsson, Margaretha Persson, Olle Melander
(2019) Journal of Hypertension, 37 p.590-595
Journal article

Letter by Schomburg and Melander Regarding Article, "Selenoprotein P Promotes the Development of Pulmonary Arterial Hypertension : A Possible Novel Therapeutic Target"

Lutz Schomburg, Olle Melander
(2019) Circulation, 139 p.722-723
Journal article (letter)

Ergothioneine is associated with reduced mortality and decreased risk of cardiovascular disease

Einar Smith, Filip Ottosson, Sophie Hellstrand, Ulrika Ericson, Marju Orho-Melander, et al.
(2019) Heart
Journal article

Hydration status affects thirst and salt preference but not energy intake or postprandial ghrelin in healthy adults : A randomised crossover trial

Harriet A. Carroll, Iain Templeman, Yung Chih Chen, Robert Edinburgh, Elaine K. Burch, et al.
(2019) Physiology and Behavior, 212
Journal article

Copeptin, B-type natriuretic peptide and cystatin C are associated with incident symptomatic PAD

Shahab Fatemi, Stefan Acosta, Anders Gottsäter, Olle Melander, Gunnar Engström, et al.
(2019) Biomarkers, 24 p.615-621
Journal article

Purine Metabolites and Carnitine Biosynthesis Intermediates Are Biomarkers for Incident Type 2 Diabetes

Filip Ottosson, Einar Smith, Widet Gallo, Céline Fernandez, Olle Melander
(2019) The Journal of clinical endocrinology and metabolism, 104 p.4921-4930
Journal article

Circulating Monocyte Chemoattractant Protein-1 and Risk of Stroke : Meta-Analysis of Population-Based Studies Involving 17 180 Individuals

Marios K. Georgakis, Rainer Malik, Harry Björkbacka, Tiberiu Alexandru Pana, Serkalem Demissie, et al.
(2019) Circulation Research, 125 p.773-782
Journal article

Dimethylguanidino Valerate : A Lifestyle-Related Metabolite Associated With Future Coronary Artery Disease and Cardiovascular Mortality

Filip Ottosson, Ulrika Ericson, Peter Almgren, Einar Smith, Louise Brunkwall, et al.
(2019) Journal of the American Heart Association, 8
Journal article

Accumulated neighbourhood deprivation and coronary heart disease : A nationwide cohort study from Sweden

Sara Larsson Lönn, Olle Melander, Casey Crump, Kristina Sundquist
(2019) BMJ Open, 9
Journal article

Monitoring of cerebral oximetry in patients with postural orthostatic tachycardia syndrome

Isabella Kharraziha, Hannes Holm, Erasmus Bachus, Olle Melander, Richard Sutton, et al.
(2019) Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 21 p.1575-1583
Journal article

Lung Cancer Risk in Never-Smokers of European Descent is Associated With Genetic Variation in the 5p15.33 TERT-CLPTM1Ll Region

Rayjean J. Hung, Olle Melander, O.Y. Gerlova
(2019) Journal of Thoracic Oncology, 14 p.1360-1369
Journal article

Coping facilitated troponin T increases and hypo-responsivity in the copeptin-HPA-axis during acute mental stress in a Black cohort : The SABPA study

Catharina Elizabeth Myburgh, Leoné Malan, Marisa Möller, Martin Magnusson, Olle Melander, et al.
(2019) Physiology & Behavior, 207 p.159-166
Journal article

Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting

Ganesh Chauhan, Arne Lindgren, Olle Melander, W. T. Longstreth, Stephanie Debette
(2019) Neurology, 92 p.486-503
Journal article

Elevated Platelet Count Appears to Be Causally Associated with Increased Risk of Lung Cancer: A Mendelian Randomization Analysis

Ying Zhu, Olle Melander, Jonas Manjer, Hans Brunnström, David C. Christiani
(2019) Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 28 p.935-942
Journal article

ST2 predicts mortality in patients with acute hypercapnic respiratory failure treated with noninvasive positive pressure ventilation.

Brynja Jónsdóttir, Marie Ziebell Severinsen, Fredrik Wowern, Carmen San Miguel, Jens P. Götze, et al.
(2019) International journal of chronic obstructive pulmonary disease, 14 p.2385-2393
Journal article

Biomarkers to guide antibiotic timing and administration in infected patients presenting to the emergency department

Mari Rosenqvist, Darius Cameron Wilson, Lena Tegnér, Maria Bengtsson-Toni, Marjaneh Peyman, et al.
(2019) Critical Care, 23
Journal article (letter)

Novel Methods for the Quantification of Dipeptidyl Peptidase 3 (DPP3) Concentration and Activity in Human Blood Samples

Linda Rehfeld, Eugenia Funk, Shalinee Jha, Peter Macheroux, Olle Melander, et al.
(2019) The Journal of Applied Laboratory Medicine, 3 p.943-953
Journal article

Genome-wide analysis yields new loci associating with aortic valve stenosis

Anna Helgadottir, Gudmar Thorleifsson, Solveig Gretarsdottir, Olafur A. Stefansson, Vinicius Tragante, et al.
(2018) Nature Communications, 9
Journal article

Prognostic significance of noncardiac syncope in the general population : A systematic review and meta-analysis

Fabrizio Ricci, Richard Sutton, Stefano Palermi, Claudio Tana, Giulia Renda, et al.
(2018) Journal of Cardiovascular Electrophysiology, 29 p.1641-1647
Journal article

miR-483-5p associates with obesity and insulin resistance and independently associates with new onset diabetes mellitus and cardiovascular disease

Widet Gallo, Jonathan Lou S. Esguerra, Lena Eliasson, Olle Melander
(2018) PLoS ONE, 13
Journal article

First Genome-Wide Association Study of Latent Autoimmune Diabetes in Adults Reveals Novel Insights Linking Immune and Metabolic Diabetes

Diana L Cousminer, Emma Ahlqvist, Mikael Åkerlund, Olle Melander, Benjamin F Voight, et al.
(2018) Diabetes Care, 41 p.2396-2403
Journal article

Plasma lactate at admission does not predict mortality and complications in hip fracture patients : a prospective observational study

Magnus H. Jonsson, Ami Hommel, Aleksandra Turkiewicz, Ulf Ekelund, Olle Melander, et al.
(2018) Scandinavian Journal of Clinical and Laboratory Investigation, 78 p.508-514
Journal article

Plasma levels of the proprotein convertase furin and incidence of diabetes and mortality

C. Fernandez, J. Rysä, P. Almgren, J. Nilsson, G. Engström, et al.
(2018) Journal of Internal Medicine, 284 p.377-387
Journal article

IgM anti-malondialdehyde low density lipoprotein antibody levels indicate coronary heart disease and necrotic core characteristics in the Nordic Diltiazem (NORDIL) study and the Integrated Imaging and Biomarker Study 3 (IBIS-3)

Victor J van den Berg, Dorian O Haskard, Artur Fedorowski, Adam Hartley, Isabella Kardys, et al.
(2018) EBioMedicine, 36 p.63-72
Journal article

Cardiovascular biomarkers and risk of low-energy fractures among middle-aged men and women—A population-based study

Maria Härstedt, Anna Holmberg, Cecilia Rogmark, Richard Sutton, Olle Melander, et al.
(2018) PLoS ONE, 13
Journal article

Characteristics and prognosis of healthy severe obesity (HSO) subjects - The Malmo Preventive Project

Maximilian Tremmel, Valeriya Lyssenko, Bengt Zöller, Gunnar Engström, Martin Magnusson, et al.
(2018) Obesity Medicine, 11 p.6-12
Journal article

Multi-ethnic genome-wide association study for atrial fibrillation

Carolina Roselli, Mark D. Chaffin, Lu Chen Weng, Stefanie Aeschbacher, Gustav Ahlberg, et al.
(2018) Nature Genetics, 50 p.1225-1233
Journal article

Detection of inflammatory biomarkers associated with postural orthostatic tachycardia syndrome: insights from the SYSTEMA cohort

Fabrizio Ricci, Jasmina Medic Spahic, Madeleine Johansson, Nay Aung, Viktor Hamrefors, et al.
(2018) European Heart Journal, Supplement, 39
Journal article

Genome-wide analysis of genetic determinants of circulating factor VII-activating protease (FSAP) activity

M. Olsson, T. M. Stanne, A. Pedersen, E. Lorentzen, E. Kara, et al.
(2018) Journal of Thrombosis and Haemostasis, 16 p.2024-2034
Journal article

Five-week yin yoga-based interventions decreased plasma adrenomedullin and increased psychological health in stressed adults : A randomized controlled trial

Daiva Daukantaitė, Una Tellhed, Rachel E Maddux, Thomas Svensson, Olle Melander
(2018) PLoS ONE, 13
Journal article

A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes

Natalie R van Zuydam, Emma Ahlqvist, Claes Ladenvall, Peter Almgren, Christina-Alexandra Schulz, et al.
(2018) Diabetes, 67 p.1414-1427
Journal article

Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes

Viktoria Gusarova, Colm O'Dushlaine, Tanya M Teslovich, Peter N Benotti, Tooraj Mirshahi, et al.
(2018) Nature Communications, 9 p.1-11
Journal article

The vasopressin system in the risk of diabetes and cardiorenal disease, and hydration as a potential lifestyle intervention

Sofia Enhörning, Olle Melander
(2018) Annals of Nutrition and Metabolism, 72 p.21-27
Journal article

A genome-wide association study of IgM antibody against phosphorylcholine : Shared genetics and phenotypic relationship to chronic lymphocytic leukemia

Xu Chen, Stefan Gustafsson, Thomas Whitington, Yan Borné, Erik Lorentzen, et al.
(2018) Human Molecular Genetics, 27 p.1809-1818
Journal article

Inflammatory biomarker profiling in classical orthostatic hypotension : Insights from the SYSTEMA cohort

Madeleine Johansson, Fabrizio Ricci, Nay Aung, Richard Sutton, Olle Melander, et al.
(2018) International Journal of Cardiology, 259 p.192-197
Journal article

Proneurotensin Predicts Cardiovascular Disease in an Elderly Population

Ayesha Fawad, Andreas Bergmann, Joachim Struck, Peter M. Nilsson, Marju Orho-Melander, et al.
(2018) Journal of Clinical Endocrinology and Metabolism, 103 p.1940-1947
Journal article

Novel subgroups of adult-onset diabetes and their association with outcomes : A data-driven cluster analysis of six variables

Emma Ahlqvist, Petter Storm, Annemari Käräjämäki, Mats Martinell, Mozhgan Dorkhan, et al.
(2018) The Lancet Diabetes and Endocrinology, 6 p.361-369
Journal article

Neurotensin is a lipid-induced gastrointestinal peptide associated with visceral adipose tissue inflammation in obesity

Ilaria Barchetta, Flavia Agata Cimini, Danila Capoccia, Laura Bertoccini, Valentina Ceccarelli, et al.
(2018) Nutrients, 10
Journal article

Risk thresholds for alcohol consumption : combined analysis of individual-participant data for 599 912 current drinkers in 83 prospective studies

Angela M. Wood, Stephen Kaptoge, Adam Butterworth, Peter Willeit, Samantha Warnakula, et al.
(2018) The Lancet, 391 p.1513-1523
Journal article

Circulating Midregional Proadrenomedullin and Risk of Incident Abdominal Aortic Aneurysm : A Prospective Longitudinal Cohort Study

Stefan Acosta, Anders Gottsäter, Gunnar Engström, Olle Melander, Moncef Zarrouk, et al.
(2018) Angiology, 69 p.333-338
Journal article

Connection between BMI-Related Plasma Metabolite Profile and Gut Microbiota

Filip Ottosson, Louise Brunkwall, Ulrika Ericson, Peter M. Nilsson, Peter Almgren, et al.
(2018) Journal of Clinical Endocrinology and Metabolism, 103 p.1491-1501
Journal article

Plasma concentration of Caspase-8 is associated with short sleep duration and the risk of incident diabetes mellitus

Thomas Svensson, Akiko Kishi Svensson, Mariusz Kitlinski, Peter Almgren, Gunnar Engström, et al.
(2018) The Journal of clinical endocrinology and metabolism, 103 p.1592-1600
Journal article

Role of blood lipids in the development of ischemic stroke and its subtypes : A mendelian randomization study

George Hindy, Gunnar Engström, Susanna C. Larsson, Matthew Traylor, Hugh S. Markus, et al.
(2018) Stroke, 49 p.820-827
Journal article

Blood lipid genetic scores, the HMGCR gene and cancer risk : A Mendelian randomization study

Marju Orho-Melander, George Hindy, Signe Borgquist, Christina Alexandra Schulz, Jonas Manjer, et al.
(2018) International Journal of Epidemiology, 47 p.495-505
Journal article

Thyroid-associated genetic polymorphisms in relation to breast cancer risk in the Malmö Diet and Cancer Study

Jasmine Brandt, Signe Borgquist, Peter Almgren, Asta Försti, Linnea Huss, et al.
(2018) International Journal of Cancer, 142 p.1309-1321
Journal article

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

Rainer Malik, Ganesh Chauhan, Matthew Traylor, Muralidharan Sargurupremraj, Yukinori Okada, et al.
(2018) Nature Genetics, 50 p.524-537
Journal article

Genome-wide interaction study of smoking behavior and non-small cell lung cancer risk in Caucasian population

Yafang Li, Xiangjun Xiao, Younghun Han, Olga Gorlova, David Qian, et al.
(2018) Carcinogenesis, 39 p.336-346
Journal article

Proteomic Profiling for Cardiovascular Biomarker Discovery in Orthostatic Hypotension

Madeleine Johansson, Fabrizio Ricci, Nay Aung, Richard Sutton, Olle Melander, et al.
(2018) Hypertension, 71 p.465-472
Journal article

Association between systemic leptin and neurotensin concentration in adult individuals with and without type 2 diabetes mellitus

I. Barchetta, G. Ciccarelli, F. A. Cimini, V. Ceccarelli, M. Orho-Melander, et al.
(2018) Journal of Endocrinological Investigation, 41 p.1159-1163
Journal article

Vascular Endothelial Growth Factor D, Pulmonary Congestion, and Incidence of Heart Failure

Yan Borné, Klas Gränsbo, Jan Nilsson, Olle Melander, Marju Orho-Melander, et al.
(2018) Journal of the American College of Cardiology, 71 p.580-582
Journal article (letter)

Separate and combined associations of obesity and metabolic health with coronary heart disease : A pan-European case-cohort analysis

Camille Lassale, Ioanna Tzoulaki, Karel G.M. Moons, Michael Sweeting, Jolanda Boer, et al.
(2018) European Heart Journal, 39 p.397-406
Journal article

Factor V Leiden paradox in a middle-aged Swedish population : A prospective study

Bengt Zöller, Olle Melander, Peter J. Svensson, Gunnar Engström
(2018) Vascular Medicine (United Kingdom), 23 p.52-59
Journal article

Interaction of dietary and genetic factors influencing body iron status and risk of type 2 diabetes within the EPIC-InterAct study

Karina Meidtner, Clara Podmore, Janine Kröger, Yvonne T. Van Der Schouw, Benedetta Bendinelli, et al.
(2018) Diabetes Care, 41 p.277-285
Journal article

B-type natriuretic peptide for prediction of incident clinically significant abdominal aortic aneurysm : A population-based prospective study

Stefan Acosta, Anders Gottsäter, Gunnar Engström, Olle Melander, Moncef Zarrouk, et al.
(2018) Vascular Medicine, 23 p.46-51
Journal article

Incident diabetes mellitus may explain the association between sleep duration and incident coronary heart disease

Akiko Kishi Svensson, Thomas Svensson, Mariusz Kitlinski, Peter Almgren, Gunnar Engström, et al.
(2018) Diabetologia, 61 p.331-341
Journal article

SNPs related to vitamin D and breast cancer risk : A case-control study

Linnea Huss, Salma Tunå Butt, Peter Almgren, Signe Borgquist, Jasmine Brandt, et al.
(2018) Breast Cancer Research, 20
Journal article

Increased midlife triglycerides predict brain β-amyloid and tau pathology 20 years later

Katarina Nägga, Anna-Märta Gustavsson, Erik Stomrud, Daniel Lindqvist, Danielle van Westen, et al.
(2018) Neurology, 90 p.1-11
Journal article

Blood Lead Levels and Decreased Kidney Function in a Population-Based Cohort

Florencia Harari, Gerd Sallsten, Anders Christensson, Marinka Petkovic, Bo Hedblad, et al.
(2018) American Journal of Kidney Diseases, 72 p.381-389
Journal article

Alcohol intake in relation to non-fatal and fatal coronary heart disease and stroke : EPIC-CVD case-cohort study

Cristian Ricci, Angela Wood, David Muller, Marc J. Gunter, Antonio Agudo, et al.
(2018) BMJ (Online), 361
Journal article

Genome-wide Scan Identifies Role for AOX1 in Prostate Cancer Survival

Weiqiang Li, Mridu Middha, Mesude Bicak, Daniel D. Sjoberg, Emily Vertosick, et al.
(2018) European Urology, 74 p.710-719
Journal article

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes article

Anubha Mahajan, Jennifer Wessel, Sara M Willems, Wei Zhao, Neil R Robertson, et al.
(2018) Nature Genetics, 50 p.559-571
Journal article

Cardiovascular risk after hospitalisation for unexplained syncope and orthostatic hypotension

Ekrem Yasa, Fabrizio Ricci, Martin Magnusson, Richard Sutton, Sabina Gallina, et al.
(2018) Heart, 104 p.487-493
Journal article

Monitoring of cerebral oximetry during head-up tilt test in adults with history of syncope and orthostatic intolerance

E Bachus, H. Holm, V Hamrefors, O Melander, R Sutton, et al.
(2018) Europace
Journal article

Probing the Virtual Proteome to Identify Novel Disease Biomarkers

Jonathan D. Mosley, Mark D. Benson, J. Gustav Smith, Olle Melander, Debby Ngo, et al.
(2018) Circulation, 138 p.2469-2481
Journal article

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

Evangelos Evangelou, Peter Almgren, Olle Melander, Paul Elliott, Mark J Caulfield
(2018) Nature Genetics, 50 p.1412-1425
Journal article

Identification of susceptibility pathways for the role of chromosome 15q25.1 in modifying lung cancer risk

Xuemei Ji, Hans Brunnström, Jonas Manjer, Olle Melander, Kim Overvad, et al.
(2018) Nature Communications, 9
Journal article

Fine mapping of MHC region in lung cancer highlights independent susceptibility loci by ethnicity

Aida Ferreiro-Iglesias, Corina Lesseur, James McKay, Rayjean J. Hung, Younghun Han, et al.
(2018) Nature Communications, 9
Journal article

FADD (Fas-Associated Protein With Death Domain), Caspase-3, and Caspase-8 and Incidence of Ischemic Stroke

Iram Faqir Muhammad, Yan Borné, Olle Melander, Marju Orho-Melander, Jan Nilsson, et al.
(2018) Stroke, 49 p.2224-2226
Journal article

Altered asparagine and glutamate homeostasis precede coronary artery disease and type 2 diabetes

Filip Ottosson, Einar Smith, Olle Melander, Céline Fernandez
(2018) Journal of Clinical Endocrinology and Metabolism, 103 p.3060-3069
Journal article

GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes

Nora Franceschini, Bo Hedblad, Cristiano Fava, Olle Melander, Arne Lindgren, et al.
(2018) Nature Communications
Journal article

Polygenic Risk Score for Coronary Heart Disease Modifies the Elevated Risk by Cigarette Smoking for Disease Incidence

George Hindy, Frans Wiberg, Peter Almgren, Olle Melander, Marju Orho-Melander
(2018) Circulation: Genomic and Precision Medicine, 11
Journal article

A multilocus genetic risk score is associated with arterial stiffness in hypertensive patients : The CARE NORTH study

Katarzyna Polonis, Michal Hoffmann, Anna Szyndler, Jacek Wolf, Robert Nowak, et al.
(2018) Journal of Hypertension, 36 p.1882-1888
Journal article

Natriuretic peptides in cardiovascular and metabolic crosstalk implications for hypertension management

Jens Jordan, Andreas L. Birkenfeld, Olle Melander, Cedric Moro
(2018) Hypertension, 72 p.270-276
Journal article review

A Genome-wide Study of Common and Rare Genetic Variants Associated with Circulating Thrombin Activatable Fibrinolysis Inhibitor

Tara M. Stanne, Maja Olsson, Erik Lorentzen, Annie Pedersen, Anders Gummesson, et al.
(2018) Thrombosis and Haemostasis, 118 p.298-308
Journal article

A genetic risk score for fasting plasma glucose is independently associatedwith arterial stiffness : A Mendelian randomization study

Mikael Gottsäter, George Hindy, Marju Orho-Melander, Peter M. Nilsson, Olle Melander
(2018) Journal of Hypertension, 36 p.809-814
Journal article

ADAMTS-7 is associated with a high-risk plaque phenotype in human atherosclerosis

Eva Bengtsson, Karin Hultman, Pontus Dunér, Giuseppe Asciutto, Peter Almgren, et al.
(2017) Scientific Reports, 7
Journal article

Genetic Interactions with Age, Sex, Body Mass Index, and Hypertension in Relation to Atrial Fibrillation : The AFGen Consortium

Lu Chen Weng, Kathryn L Lunetta, Martina Müller-Nurasyid, Albert Vernon Smith, Sébastien Thériault, et al.
(2017) Scientific Reports, 7
Journal article

Dimethylguanidino valeric acid is a marker of liver fat and predicts diabetes

John F. O’Sullivan, Jordan E. Morningstar, Qiong Yang, Baohui Zheng, Yan Gao, et al.
(2017) Journal of Clinical Investigation, 127 p.4394-4402
Journal article

Elevated Markers of Death Receptor-Activated Apoptosis are Associated with Increased Risk for Development of Diabetes and Cardiovascular Disease

Ingrid Yao Mattisson, Harry Björkbacka, Maria Wigren, Andreas Edsfeldt, Olle Melander, et al.
(2017) EBioMedicine, 26 p.187-197
Journal article

Complement C3 Associates With Incidence of Diabetes, but No Evidence of a Causal Relationship

Yan Borné, Iram Faqir Muhammad, Laura Lorés-Motta, Bo Hedblad, Peter M. Nilsson, et al.
(2017) The Journal of clinical endocrinology and metabolism, 102 p.4477-4485
Journal article

Genetic determinants of circulating GIP and GLP-1 concentrations

Peter Almgren, Andreas Lindqvist, Ulrika Krus, Liisa H. Hakaste, Emilia Ottosson Laakso, et al.
(2017) JCI Insight, 2
Journal article

Genetic determinants of growth hormone and GH-related phenotypes

Erik Hallengren, Peter Almgren, Malin Svensson, Widet Gallo, Gunnar Engström, et al.
(2017) BMC Genomics, 18 p.1-9
Journal article

Low Adrenomedullin and Endothelin-1 Predict Cardioinhibitory Response During Vasovagal Reflex in Adults Over 40 Years of Age

Viktor Hamrefors, David Nilsson, Olle Melander, Richard Sutton, Artur Fedorowski
(2017) Circulation: Arrhythmia and Electrophysiology, 10
Journal article

Vasopressin : novel roles for a new hormone – Emerging therapies in cardiometabolic and renal diseases

O. Melander
(2017) Journal of Internal Medicine, 282 p.281-283
Journal article review

New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals

Aldi T. Kraja, James P. Cook, Helen R. Warren, Praveen Surendran, Chunyu Liu, et al.
(2017) Circulation: Cardiovascular Genetics, 10
Journal article

A combination of plasma phospholipid fatty acids and its association with incidence of type 2 diabetes : The EPIC-InterAct case-cohort study

Fumiaki Imamura, Stephen J. Sharp, Albert Koulman, Matthias B. Schulze, Janine Kröger, et al.
(2017) PLoS Medicine, 14
Journal article

Eosinophil Cationic Protein, Carotid Plaque, and Incidence of Stroke

Johannes Sundström, Martin Söderholm, Yan Borné, Jan Nilsson, Margaretha Persson, et al.
(2017) Stroke, 48 p.2686-2692
Journal article

Blood Metabolic Signatures of Body Mass Index : A Targeted Metabolomics Study in the EPIC Cohort

Marion Carayol, Michael F. Leitzmann, Pietro Ferrari, Raul Zamora-Ros, David Achaintre, et al.
(2017) Journal of Proteome Research, 16 p.3137-3146
Journal article

N-Terminal Prosomatostatin and Risk of Vascular Dementia

Hannes Holm, Katarina Nägga, Erik D. Nilsson, Fabrizio Ricci, Eduardo Cinosi, et al.
(2017) Cerebrovascular Diseases, 44 p.259-265
Journal article

Plasma stem cell factor levels are associated with risk of cardiovascular disease and death

H Björkbacka, I Yao Mattisson, M Wigren, O Melander, G. N. Fredrikson, et al.
(2017) Journal of Internal Medicine, 282 p.508-521
Journal article

Two Liters a Day Keep the Doctor Away? Considerations on the Pathophysiology of Suboptimal Fluid Intake in the Common Population

Florian Lang, Isabelle Guelinckx, Guillaume Lemetais, Olle Melander
(2017) Kidney and Blood Pressure Research, 42 p.483-494
Journal article review

Type 2 diabetes, glucose, insulin, BMI, and ischemic stroke subtypes : Mendelian randomization study

Susanna C. Larsson, Robert A. Scott, Matthew Traylor, Claudia Langenberg, George Hindy, et al.
(2017) Neurology, 89 p.454-460
Journal article

LDL subfractions are associated with incident cardiovascular disease in the Malmö Prevention Project Study

Dov Shiffman, Judy Z Louie, Michael P Caulfield, Peter M. Nilsson, James J Devlin, et al.
(2017) Atherosclerosis, 263 p.287-292
Journal article

Clonal Hematopoiesis and risk of atherosclerotic cardiovascular disease

Siddhartha Jaiswal, P Natarajan, A. J. Silver, C. J. Gibson, Alexander G. Bick, et al.
(2017) New England Journal of Medicine, 377 p.111-121
Journal article

Lp-PLA₂ activity and mass for prediction of incident abdominal aortic aneurysms : A prospective longitudinal cohort study

Stefan Acosta, Soumia Taimour, Anders Gottsäter, Margaretha Persson, Gunnar Engström, et al.
(2017) Atherosclerosis, 262 p.14-18
Journal article

Utilization of genetic data can improve the prediction of type 2 diabetes incidence in a Swedish cohort

Hadi Zarkoob, Sarah Lewinsky, Peter Almgren, Olle Melander, Hossein Fakhrai-Rad1
(2017) PLoS ONE, 12
Journal article

Antiadrenergic autoimmunity in postural tachycardia syndrome

Artur Fedorowski, Hongliang Li, Xichun Yu, Kristi A. Koelsch, Valerie M. Harris, et al.
(2017) Europace, 19 p.1211-1219
Journal article

Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes

James D. McKay, Rayjean J. Hung, Younghun Han, Xuchen Zong, Robert Carreras-Torres, et al.
(2017) Nature Genetics, 49 p.1126-1132
Journal article (letter)

Dynamic high-sensitivity troponin elevations in atrial fibrillation patients might not be associated with significant coronary artery disease

Johan Thelin, Olle Melander
(2017) BMC Cardiovascular Disorders, 17
Journal article

Effect of increased water intake on plasma copeptin in healthy adults

Guillaume Lemetais, Olle Melander, Mariacristina Vecchio, Jeanne H. Bottin, Sofia Enhörning, et al.
(2017) European Journal of Nutrition , p.1-8
Journal article

Circulating cadmium concentration and risk of aortic aneurysms : A nested case-control study within the Malmö Diet and Cancer cohort

Björn Fagerberg, Yan Borné, Gerd Sallsten, Gustav Smith, Stefan Acosta, et al.
(2017) Atherosclerosis, 261 p.37-43
Journal article

Genetic variation in the ADIPOQ gene, adiponectin concentrations and risk of colorectal cancer : a Mendelian Randomization analysis using data from three large cohort studies

Katharina Nimptsch, Mingyang Song, Krasimira Aleksandrova, Michail Katsoulis, Heinz Freisling, et al.
(2017) European Journal of Epidemiology, 32 p.419-430
Journal article

Fasting levels of growth hormone are associated with carotid intima media thickness but are not affected by fluvastatin treatment

Erik Hallengren, Peter Almgren, Maria Rosvall, Gerd Östling, Margaretha Persson, et al.
(2017) BMC Cardiovascular Disorders, 17
Journal article

Biomarkers of microvascular endothelial dysfunction predict incident dementia : a population-based prospective study

Hannes Holm, K Nägga, E D Nilsson, F Ricci, O Melander, et al.
(2017) Journal of Internal Medicine, 282 p.94-101
Journal article

Plasma metabolite profiles, cellular cholesterol efflux, and non-traditional cardiovascular risk in patients with CKD

Anjali Ganda, Laurent Yvan-Charvet, Yuan Zhang, Eric J Lai, Renu Regunathan-Shenk, et al.
(2017) Journal of Molecular and Cellular Cardiology, 112 p.114-122
Journal article

Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function

Philipp S. Wild, Janine F. Felix, Arne Schillert, Alexander Teumer, Ming-Huei Chen, et al.
(2017) Journal of Clinical Investigation, 127 p.1798-1812
Journal article

Syndromes of orthostatic intolerance and syncope in young adults

Viktor Hamrefors, Jasmina Medic Spahic, David Nilsson, Martin Senneby, Richard Sutton, et al.
(2017) Open Heart, 4
Journal article

Pro-atrial natriuretic peptide and prediction of atrial fibrillation and stroke : The Malmö Preventive Project

John Berntsson, Gustav Smith, Peter M. Nilsson, Bo Hedblad, Olle Melander, et al.
(2017) European Journal of Preventive Cardiology, 24 p.788-795
Journal article

FADD, Caspase-3, and Caspase-8 and Incidence of Coronary Events

Ling Xue, Yan Borné, Ingrid Yao Mattisson, Maria Wigren, Olle Melander, et al.
(2017) Arteriosclerosis, Thrombosis, and Vascular Biology, 37 p.983-989
Journal article

No relation between biomarkers at age 47-49 and aortic diameter after 14-19 years of follow-up - a population-based study

Soumia Taimour, Moncef Zarrouk, Jan Holst, Olle Melander, Gunnar Engström, et al.
(2017) Vasa - European Journal of Vascular Medicine, 46 p.291-295
Journal article

A genetic risk score for CAD, psychological stress, and their interaction as predictors of CAD, fatal MI, non-fatal MI and cardiovascular death

Thomas Svensson, Mariusz Kitlinski, Gunnar Engström, Olle Melander
(2017) PLoS ONE, 12
Journal article

Vasoactive peptides associate with treatment outcome ofbevacizumab-containing therapy in metastatic colorectal cancer

Helga Hagman, Pär-Ola Bendahl, Olle Melander, Jan Sundberg, Anders Johnsson, et al.
(2017) Acta Oncologica, 56 p.653-660
Journal article

Genetic Risk Prediction of Atrial Fibrillation

Steven A Lubitz, Xiaoyan Yin, Henry J. Lin, Matthew Kolek, Gustav G. Smith, et al.
(2017) Circulation, 135 p.1311-1320
Journal article

Lifestyle and dietary determinants of serum apolipoprotein A1 and apolipoprotein B concentrations : Cross-sectional analyses within a Swedish Cohort of 24,984 individuals

Kasper Frondelius, Madelene Borg, Ulrika Ericson, Yan Borné, Olle Melander, et al.
(2017) Nutrients, 9
Journal article

The association between adult attained height and sitting height with mortality in the European prospective investigation into cancer and nutrition (EPIC)

Norie Sawada, Petra A. Wark, Melissa A Merritt, Shoichiro Tsugane, Heather A. Ward, et al.
(2017) PLoS ONE, 12
Journal article

Genetic variation at 16q24.2 is associated with small vessel stroke

Matthew Traylor, Rainer Malik, Mike A. Nalls, Ioana Cotlarciuc, Farid Radmanesh, et al.
(2017) Annals of Neurology, 81 p.383-394
Journal article

SOS2 and ACP1 Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function

Man Li, Yong Li, Olivia Weeks, Vladan Mijatovic, Alexander Teumer, et al.
(2017) Journal of the American Society of Nephrology: JASN, 28 p.981-994
Journal article

Soluble Urokinase-type Plasminogen Activator Receptor (suPAR) and Impaired Kidney Function in the Population-based Malmö Diet and Cancer Study

Christina-Alexandra Schulz, Margaretha Persson, Anders Christensson, George Hindy, Peter Almgren, et al.
(2017) Kidney International Reports, 2 p.239-247
Journal article

Sepsis Alert – a triage model that reduces time to antibiotics and length of hospital stay

Mari Rosenqvist, Emma Fagerstrand, Peter Lanbeck, Olle Melander, Per Åkesson
(2017) Infectious Diseases, 49 p.507-513
Journal article

Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease

Thomas R. Webb, Jeanette Erdmann, Kathleen E. Stirrups, Nathan O. Stitziel, Nicholas G D Masca, et al.
(2017) Journal of the American College of Cardiology, 69 p.823-836
Journal article

Psychological stress and risk of incident atrial fibrillation in men and women with known atrial fibrillation genetic risk scores

Thomas Svensson, Mariusz Kitlinski, Gunnar Engström, Olle Melander
(2017) Scientific Reports, 7
Journal article

Longitudinal and postural changes of blood pressure predict dementia : the Malmö Preventive Project

Hannes Holm, Katarina Nägga, Erik D. Nilsson, Olle Melander, Lennart Minthon, et al.
(2017) European Journal of Epidemiology, 32 p.327-336
Journal article

IL-8 predicts early mortality in patients with acute hypercapnic respiratory failure treated with noninvasive positive pressure ventilation

Brynja Jónsdóttir, Åsa Jaworowski, Carmen San Miguel, Olle Melander
(2017) BMC Pulmonary Medicine, 17
Journal article

Relationship between selected DNA polymorphisms and coronary artery disease complications

Marcin Wirtwein, Olle Melander, Marketa Sjögren, Michal Hoffmann, Krzysztof Narkiewicz, et al.
(2017) International Journal of Cardiology, 228 p.814-820
Journal article

Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer

Thomas J. Hoffmann, Michael N. Passarelli, Rebecca E. Graff, Nima C. Emami, Lori C. Sakoda, et al.
(2017) Nature Communications, 8
Journal article

Prediction of treatment response in patients with newly diagnosed type 2 diabetes : The Skaraborg diabetes register

Miriam Pikkemaat, Olle Melander, Per Hjerpe, Kristina Bengtsson Boström
(2017) Journal of Diabetes and its Complications, 31 p.854-858
Journal article

Elevated ambulatory systolic-diastolic pressure regression index is genetically determined in hypertensive patients with coronary heart disease

Marcin Wirtwein, Olle Melander, Marketa Sjőgren, Michal Hoffmann, Krzysztof Narkiewicz, et al.
(2017) Blood Pressure, 26 p.174-180
Journal article

High Level of Fasting Plasma Proenkephalin-A Predicts Deterioration of Kidney Function and Incidence of CKD

Christina-Alexandra Schulz, Anders Christensson, Ulrika Ericson, Peter Almgren, George Hindy, et al.
(2017) Journal of the American Society of Nephrology: JASN, 28 p.291-303
Journal article

Amino Acid Signatures to Evaluate the Beneficial Effects of Weight Loss

Nina Geidenstam, Martin Magnusson, Anders P H Danielsson, Robert E Gerszten, Thomas J Wang, et al.
(2017) International Journal of Endocrinology, 2017
Journal article

Midlife risk factor exposure and incidence of cardiac arrest depending on cardiac or non-cardiac origin

Marcus Andreas Ohlsson, Linn Maria Anna Kennedy, Tord Juhlin, Olle Melander
(2017) International Journal of Cardiology, 240 p.398-402
Journal article

Acute and chronic hyperglycemic effects of vasopressin in normal rats : Involvement of V_1A receptors

Christopher Taveau, Catherine Chollet, Daniel G. Bichet, Gilberto Velho, Gilles Guillon, et al.
(2017) American Journal of Physiology - Endocrinology and Metabolism, 312 p.127-135
Journal article

Obesity, metabolic factors and risk of different histological types of lung cancer : A Mendelian randomization study

Robert Carreras-Torres, Mattias Johansson, Philip C Haycock, Kaitlin H Wade, Caroline L Relton, et al.
(2017) PLoS ONE, 12
Journal article

Hospital admissions for orthostatic hypotension and syncope in later life : insights from the Malmö Preventive Project

Fabrizio Ricci, Lamberto Manzoli, Richard Sutton, Olle Melander, Maria E. Flacco, et al.
(2017) Journal of Hypertension, 35 p.776-783
Journal article

Rare Variant Analysis of Human and Rodent Obesity Genes in Individuals with Severe Childhood Obesity

A. E. Hendricks, E. G. Bochukova, Gaëlle Marenne, J. M. Keogh, N Atanassova, et al.
(2017) Scientific Reports, 7
Journal article

Novel genetic loci associated with long-term deterioration in blood lipid concentrations and coronary artery disease in European adults

Tibor V. Varga, Azra Kurbasic, Mattias Aine, Pontus Eriksson, Ashfaq Ali, et al.
(2017) International Journal of Epidemiology, 46 p.1211-1222
Journal article

Data Descriptor: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

Jason Flannick, Christian Fuchsberger, Anubha Mahajan, Tanya M Teslovich, Vineeta Agarwala, et al.
(2017) Scientific Data, 4
Journal article

Exome-wide association study of plasma lipids in >300,000 individuals

Dajiang J Liu, Gina M. Peloso, Haojie Yu, Adam S. Butterworth, Anubha Mahajan, et al.
(2017) Nature Genetics, 49 p.1758-1766
Journal article

Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease

Wei Zhao, Asif Rasheed, Emmi Tikkanen, Jung-Jin Lee, Adam S. Butterworth, et al.
(2017) Nature Genetics, 49 p.1450-1457
Journal article

Metabolic Mediators of the Effects of Family History and Genetic Risk Score on Coronary Heart Disease-Findings from the Malmö Diet and Cancer Study

Josef Fritz, Dov Shiffman, Olle Melander, Hayato Tada, Hanno Ulmer
(2017) Journal of the American Heart Association, 6
Journal article

A low-frequency inactivating AKT2 variant enriched in the finnish population is associated with fasting insulin levels and type 2 diabetes risk

Alisa Manning, Claes Ladenvall, Peter Nilsson, Tibor V. Varga, Paul Franks, et al.
(2017) Diabetes, 66 p.2019-2032
Journal article

Cardiometabolic biomarkers are predictors of readmission and death in patients hospitalized for acute dyspnea

Nathalie Lund, Klas Gränsbo, Camilla Wernersson, Olle Melander
(2016) American Journal of Emergency Medicine, 35 p.610-614
Journal article

Genetic risk, adherence to a healthy lifestyle, and coronary disease

Amit V. Khera, Connor A. Emdin, Isabel Drake, Pradeep Natarajan, Alexander G. Bick, et al.
(2016) New England Journal of Medicine, 375 p.2349-2358
Journal article

Use of low density lipoprotein particle number levels as an aid in statin treatment decisions for intermediate risk patients: A cost-effectiveness analysis

Dov Shiffman, Andre R. Arellano, Michael P. Caulfield, Judy Z. Louie, Lance A. Bare, et al.
(2016) BMC Cardiovascular Disorders, 16
Journal article

Polypharmacy and adverse outcomes after hip fracture surgery

Maria Härstedt, Cecilia Rogmark, Richard Sutton, Olle Melander, Artur Fedorowski
(2016) Journal of Orthopaedic Surgery and Research, 11
Journal article

Validation of the good outcome following attempted resuscitation score on in-hospital cardiac arrest in southern Sweden

Marcus Andreas Ohlsson, Linn Maria Kennedy, Mark H. Ebell, Tord Juhlin, Olle Melander
(2016) International Journal of Cardiology, 221 p.294-297
Journal article

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

Georg B. Ehret, Teresa Ferreira, Daniel I. Chasman, Anne U. Jackson, Ellen M. Schmidt, et al.
(2016) Nature Genetics, 48 p.1171-1184
Journal article

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

Praveen Surendran, Fotios Drenos, Robin Young, Helen Warren, James P. Cook, et al.
(2016) Nature Genetics, 48 p.1151-1161
Journal article

Advances in integrating traditional and omic biomarkers when analyzing the effects of the mediterranean diet intervention in cardiovascular prevention

Montserrat Fitó, Olle Melander, José Alfredo Martínez, Estefanía Toledo, Christian Carpéné, et al.
(2016) International Journal of Molecular Sciences, 17
Journal article review

The Relationship Between Gene Polymorphisms and Dipping Profile in Patients With Coronary Heart Disease

Marcin Wirtwein, Olle Melander, Marketa Sjögren, Michal Hoffmann, Krzysztof Narkiewicz, et al.
(2016) American Journal of Hypertension, 29 p.1094-1102
Journal article

N-terminal prosomatostatin as a risk marker for cardiovascular disease and diabetes in a general population

Tore Hedbäck, Peter Almgren, Peter M. Nilsson, Olle Melander
(2016) Journal of Clinical Endocrinology and Metabolism, 101 p.3437-3444
Journal article

Spontaneous vs nitroglycerin-induced vasovagal reflex on head-up tilt : Are there neuroendocrine differences?

David Nilsson, Richard Sutton, Olle Melander, Artur Fedorowski
(2016) Heart Rhythm, 13 p.1674-1678
Journal article

Exome array analysis of ischaemic stroke : results from a southern Swedish study

M Söderholm, P Almgren, K Jood, T M Stanne, Mats Olsson, et al.
(2016) European Journal of Neurology, 23 p.1722-1728
Journal article

Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits

Nathalie Chami, Ming Huei Chen, Andrew J. Slater, John D. Eicher, Evangelos Evangelou, et al.
(2016) American Journal of Human Genetics, 99 p.8-21
Journal article

Increased Levels of Copeptin, a Surrogate Marker of Arginine Vasopressin, Are Associated with an Increased Risk of Chronic Kidney Disease in a General Population

Irina Tasevska, Sofia Enhörning, Anders Christensson, Margaretha Persson, Peter M. Nilsson, et al.
(2016) American Journal of Nephrology, 44 p.22-28
Journal article

Genome wide association study identifies two loci associated with cadmium in erythrocytes among never-smokers

Yan Borné, Martin Söderholm, Lars Barregard, Björn Fagerberg, Margaretha Persson, et al.
(2016) Human Molecular Genetics, 25 p.2342-2348
Journal article

Modifiable causes of premature death in middle-age in Western Europe : Results from the EPIC cohort study

David C. Muller, Neil Murphy, Mattias Johansson, Pietro Ferrari, Konstantinos K. Tsilidis, et al.
(2016) BMC Medicine, 14
Journal article

Vasopressin, from regulator to disease predictor for diabetes and cardiometabolic risk

Olle Melander
(2016) Annals of Nutrition and Metabolism, 68 p.24-28
Journal article

Adrenomedullin and endothelin-1 are associated with myocardial injury and death in septic shock patients

Oscar Lundberg, Lill Bergenzaun, Jörgen Rydén, Mari Rosenqvist, Olle Melander, et al.
(2016) Critical Care, 20
Journal article

Cardiovascular risk factors and ischemic heart disease

Roberto Elosua, Carla Lluís-Ganella, Isaac Subirana, Aki Havulinna, Kristi Läll, et al.
(2016) Circulation: Cardiovascular Genetics, 9 p.279-286
Journal article

An obligatory role for neurotensin in high-fat-diet-induced obesity

Jing Li, Jun S. Song, Yekaterina Y. Zaytseva, Yajuan Liu, Piotr Rychahou, et al.
(2016) Nature, 533 p.411-415
Journal article (letter)

Cystatin C and risk of diabetes and the metabolic syndrome - Biomarker and genotype association analyses

Martin Magnusson, John Molvin, Gunnar Engström, Patrik Svensson, Margaretha Persson, et al.
(2016) PLoS ONE, 11
Journal article

Coding variation in ANGPTL4, LPL, and SVEP1 and the risk of coronary disease

Nathan O. Stitziel, Kathleen E. Stirrups, Nicholas G D Masca, Jeanette Erdmann, Paola G. Ferrario, et al.
(2016) New England Journal of Medicine, 374 p.1134-1144
Journal article

Germline genetics of cancer of unknown primary (CUP) and its specific subtypes.

Kari Hemminki, Bowang Chen, Abhishek Kumar, Olle Melander, Jonas Manjer, et al.
(2016) Oncotarget, 7 p.22140-22149
Journal article

Risk factor exposure in individuals free from cardiovascular disease differs according to age at first myocardial infarction.

Klas Gränsbo, Peter Almgren, Peter Nilsson, Bo Hedblad, Gunnar Engström, et al.
(2016) European Heart Journal, 37 p.1977-1981
Journal article

Apo-lipoproteins, lipids and risk of cancer.

Signe Borgquist, Talha Butt, Peter Almgren, Dov Shiffman, Tanja Stocks, et al.
(2016) International Journal of Cancer, 138 p.2648-2656
Journal article

Hyponatremia in the Emergency Department: Could Biomarkers Help in Diagnosis and Treatment?

Karin Olsson, Sofia Enhörning, Bertil Öhlin, Olle Melander
(2016) Open Journal of Emergency Medicine, 4 p.11-22
Journal article

Total and Differential Leukocyte Counts in Relation to Incidence of Diabetes Mellitus: A Prospective Population-Based Cohort Study.

Yan Borné, Gustav Smith, Peter Nilsson, Olle Melander, Bo Hedblad, et al.
(2016) PLoS ONE, 11
Journal article

Glucose-Dependent Insulinotropic Polypeptide (GIP) Stimulates Osteopontin Expression in the Vasculature via Endothelin-1 and CREB.

Lisa Berglund, Valeriya Lyssenko, Claes Ladenvall, Olga Kotova, Andreas Edsfeldt, et al.
(2016) Diabetes, 65 p.239-254
Journal article

Adult height, coronary heart disease and stroke: a multi-locus Mendelian randomization meta-analysis.

Eveline Nüesch, Caroline Dale, Tom M Palmer, Jon White, Brendan J Keating, et al.
(2016) International Journal of Epidemiology, 45 p.1927-1937
Journal article

Inflammatory biomarkers predicting prognosis in patients with acute dyspnea.

Karolin Wiklund, Klas Gränsbo, Nathalie Lund, Marjaneh Peyman, Lena Tegner, et al.
(2016) American Journal of Emergency Medicine, 34 p.370-374
Journal article

Orthostatic Hypotension and Cardiac Changes After Long-Term Follow-Up.

Martin Magnusson, Hannes Holm, Erasmus Bachus, Peter Nilsson, Margrét Leosdottir, et al.
(2016) American Journal of Hypertension, 29 p.52-847
Journal article

Copeptin predicts coronary artery disease cardiovascular and total mortality.

Irina Tasevska, Sofia Enhörning, Margaretha Persson, Peter Nilsson, Olle Melander
(2016) Heart, 102 p.127-132
Journal article

Genetic vasopressin 1b receptor variance in overweight and diabetes mellitus.

Sofia Enhörning, Marketa Sjögren, Bo Hedblad, Peter Nilsson, Joachim Struck, et al.
(2016) European Journal of Endocrinology, 174 p.69-75
Journal article

Gene variance in the nicotinic receptor cluster (CHRNA5-CHRNA3-CHRNB4) predicts death from cardiopulmonary disease and cancer in smokers.

Sara Halldén, Marketa Sjögren, Bo Hedblad, Gunnar Engström, Viktor Hamrefors, et al.
(2016) Journal of Internal Medicine, 279 p.388-398
Journal article

A stop-codon of the phosphodiesterase 11A gene is associated with elevated blood pressure and measures of obesity.

Therese Ohlsson, Arne Lindgren, Gunnar Engström, Christina Jern, Olle Melander
(2016) Journal of Hypertension, 34 p.445-451
Journal article

Genetic loci on chromosome 5 are associated with circulating levels of interleukin-5 and eosinophil count in a European population with high risk for cardiovascular disease.

Olga McLeod, Angela Silveira, Elsa Valdes-Marquez, Harry Björkbacka, Peter Almgren, et al.
(2016) Cytokine, 81 p.1-9
Journal article

Tilt testing results are influenced by tilt protocol.

Dorota Zyśko, Artur Fedorowski, David Nilsson, Jerzy Rudnicki, Jacek Gajek, et al.
(2016) Europace, 18 p.1108-1112
Journal article

Atrial Natriuretic Peptide in the high normal range is associated with lower prevalence of insulin resistance.

Amra Jujic, Peter Nilsson, Margaretha Persson, Jens Juul Holst, Signe Sørensen Torekov, et al.
(2016) The Journal of clinical endocrinology and metabolism, 101 p.1372-1380
Journal article

Postprandial Levels of Branch Chained and Aromatic Amino Acids Associate with Fasting Glycaemia

Filip Ottosson, Ulrika Ericson, Peter Almgren, Jeanette Nilsson, Martin Magnusson, et al.
(2016) Journal of Amino Acids, 2016
Journal article

Proinflammatory Role of Sphingolipids and Glycosphingolipids in the Human Atherosclerotic Plaque

Andreas Edsfeldt, Pontus Dunér, Marcus Ståhlman, Ines G Mollet, Giuseppe Asciutto, et al.
(2016) Arteriosclerosis, Thrombosis and Vascular Biology, 36 p.1132-1140
Journal article

Orthostatic Hypotension and Elevated Resting Heart Rate Predict Low-Energy Fractures in the Population : The Malmö Preventive Project

Viktor Hamrefors, Maria Härstedt, Anna Holmberg, Cecilia Rogmark, Richard Sutton, et al.
(2016) PLoS ONE, 11 p.0154249-0154249
Journal article

Identification of shared and unique serum lipid profiles in diabetes mellitus and myocardial infarction

Sanela Kjellqvist, Christian Klose, Michal A. Surma, George Hindy, Inês G. Mollet, et al.
(2016) Journal of the American Heart Association, 5
Journal article

Novel microRNA regulators of atrial natriuretic peptide production

Connie Wu, Pankaj Arora, Obiajulu Agha, Liam A. Hurst, Kaitlin Allen, et al.
(2016) Molecular and Cellular Biology, 36 p.1977-1987
Journal article

Hälsosam livsstil kompenserar för genetisk risk för hjärtsjukdom

Isabel Drake, Olle Melander, Marju Orho-Melander
(2016) Läkartidningen, 113
Journal article

BRCA2 gene mutations and coagulation-associated biomarkers

Pedro Perez-Segura, José J. Zamorano-León, Daniel Acosta, Juana María Santos-Sancho, Javier Modrego, et al.
(2016) Thrombosis and Haemostasis, 115 p.415-423
Journal article

Copeptin, a Marker of Vasopressin, Predicts Vascular Dementia but not Alzheimer's Disease

Erik D. Nilsson, Olle Melander, Sölve Elmståhl, Eva Lethagen, Lennart Minthon, et al.
(2016) Journal of Alzheimer's Disease, 52 p.1047-1053
Journal article

The genetic architecture of type 2 diabetes

Christian Fuchsberger, Tibor V. Varga, Claes Ladenvall, Jasmina Kravic, Paul Franks, et al.
(2016) Nature, 536 p.41-47
Journal article

Identification of additional risk loci for stroke and small vessel disease: a meta-analysis of genome-wide association studies

Ganesh Chauhan, Arne Lindgren, Olle Melander, Stéphanie Debette
(2016) The Lancet Neurology, 15 p.695-707
Journal article

Loci associated with ischaemic stroke and its subtypes (SiGN): A genome-wide association study

Sara L Pulit, Hossein Delavaran, Gunnar Engström, Andreea Ilinca, Olle Melander, et al.
(2016) The Lancet Neurology, 15 p.174-184
Journal article

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

Pattaro C., C. Fava, B. Hedblad, O. Melander, P. Nilsson, et al.
(2016) Nature Communications, 7
Journal article

The effect of smoking on carotid intima-media thickness progression rate and rate of lumen diameter reduction.

Kristina Hansen, Gerd Östling, Margaretha Persson, Peter Nilsson, Olle Melander, et al.
(2015) European Journal of Internal Medicine
Journal article

Early rule-out of acute coronary syndrome using undetectable levels of high sensitivity troponin T.

Johan Thelin, Olle Melander, Bertil Öhlin
(2015) European Heart Journal: Acute Cardiovascular Care, 4 p.403-409
Journal article

Risk prediction by genetic risk scores for coronary heart disease is independent of self-reported family history.

Hayato Tada, Olle Melander, Judy Z Louie, Joseph J Catanese, Charles M Rowland, et al.
(2015) European Heart Journal
Journal article

Inverse relationship between a genetic risk score of 31 BMI loci and weight change before and after reaching middle age.

Gull Rukh, Shafqat Ahmad, Ulrika Ericson, George Hindy, Tanja Stocks, et al.
(2015) International Journal of Obesity
Journal article

Analysis of Low Frequency Protein Truncating Stop-Codon Variants and Fasting Concentration of Growth Hormone.

Erik Hallengren, Peter Almgren, Gunnar Engström, Margaretha Persson, Olle Melander
(2015) PLoS ONE, 10
Journal article

The Early-Onset Myocardial Infarction Associated PHACTR1 Gene Regulates Skeletal and Cardiac Alpha-Actin Gene Expression.

Annina Kelloniemi, Zoltan Szabo, Raisa Serpi, Juha Näpänkangas, Pauli Ohukainen, et al.
(2015) PLoS ONE, 10
Journal article

Basal Plasma Levels of Copeptin are Elevated in Inactive Inflammatory Bowel Disease after Bowel Resection.

Bodil Ohlsson, Olle Melander
(2015) Drug Target Insights, 9 p.21-27
Journal article

Sex-Specific Effects of Adiponectin on Carotid Intima-Media Thickness and Incident Cardiovascular Disease.

Jonas Persson, Rona J Strawbridge, Olga McLeod, Karl Gertow, Angela Silveira, et al.
(2015) Journal of the American Heart Association, 4
Journal article

Distinct metabolomic signatures are associated with longevity in humans.

Susan Cheng, Martin G Larson, Elizabeth L McCabe, Joanne M Murabito, Eugene P Rhee, et al.
(2015) Nature Communications, 6
Journal article

Risk profiles for aortic dissection and ruptured or surgically treated aneurysms: a prospective cohort study.

Maya Landenhed Smith, Gunnar Engström, Anders Gottsäter, Michael P Caulfield, Bo Hedblad, et al.
(2015) Journal of the American Heart Association, 4 p.001513-001513
Journal article

Orthostatic Changes in Hemodynamics and Cardiovascular Biomarkers in Dysautonomic Patients.

David Nilsson, Richard Sutton, Widet Tas, Philippe Burri, Olle Melander, et al.
(2015) PLoS ONE, 10
Journal article

Cystatin C Is Not Causally Related to Coronary Artery Disease.

Patrik Svensson, Peter Almgren, Bo Hedblad, Gunnar Engström, Margaretha Persson, et al.
(2015) PLoS ONE, 10
Journal article

Mendelian randomization of blood lipids for coronary heart disease

Michael V. Holmes, Folkert W. Asselbergs, Tom M. Palmer, Fotios Drenos, Matthew B. Lanktree, et al.
(2015) European Heart Journal, 36 p.539-539
Journal article

Intakes of omega-3 polyunsaturated fatty acids and blood pressure change over time: Possible interaction with genes involved in 20-HETE and EETs metabolism.

Angela Tagetti, Ulrika Ericson, Martina Montagnana, Elisa Danese, Peter Almgren, et al.
(2015) Prostaglandins & other Lipid Mediators, 120 p.126-133
Journal article

WDR12, a Member of Nucleolar PeBoW-Complex, Is Up-Regulated in Failing Hearts and Causes Deterioration of Cardiac Function.

Anne-Mari Moilanen, Jaana Rysä, Leena Kaikkonen, Teemu Karvonen, Erja Mustonen, et al.
(2015) PLoS ONE, 10
Journal article

Copeptin is an independent predictor of diabetic heart disease and death.

Sofia Enhörning, Bo Hedblad, Peter Nilsson, Gunnar Engström, Olle Melander
(2015) American Heart Journal, 169 p.549-549
Journal article

Dimethylglycine Deficiency and the Development of Diabetes mellitus.

Martin Magnusson, Thomas J Wang, Clary Clish, Gunnar Engström, Peter Nilsson, et al.
(2015) Diabetes, 64 p.3010-3016
Journal article

Diagnostic and short-term prognostic utility of plasma pro-enkephalin (pro-ENK) for acute kidney injury in patients admitted with sepsis in the emergency department

Rossella Marino, Joachim Struck, Oliver Hartmann, Alan S. Maisel, Miriam Rehfeldt, et al.
(2015) Journal of Nephrology, 28 p.717-724
Journal article

Using genetics to test the causal relationship of total adiposity and periodontitis: Mendelian randomization analyses in the Gene-Lifestyle Interactions and Dental Endpoints (GLIDE) Consortium.

Dmitry Shungin, Marilyn C Cornelis, Kimon Divaris, Birte Holtfreter, John R Shaffer, et al.
(2015) International Journal of Epidemiology, 44 p.638-650
Journal article

Impact of comorbidity on 6-month hospital readmission and mortality after hip fracture surgery.

Maria Härstedt, Cecilia Rogmark, Richard Sutton, Olle Melander, Artur Fedorowski
(2015) Injury, 46 p.713-718
Journal article

Plasma level of the endogenous sodium pump ligand marinobufagenin is related to the salt-sensitivity in men.

Olga V Fedorova, Edward G Lakatta, Alexei Y Bagrov, Olle Melander
(2015) Journal of Hypertension, 33 p.534-541
Journal article

Genetic risk, coronary heart disease events, and the clinical benefit of statin therapy: an analysis of primary and secondary prevention trials.

Jessica L Mega, Nathan O Stitziel, Gustav Smith, Daniel I Chasman, Mark J Caulfield, et al.
(2015) The Lancet, 385 p.2264-2271
Journal article

Body mass index and the risk of giant cell arteritis-results from a prospective study.

Karin Jakobsson, Lennart Jacobsson, Kenneth Warrington, Eric L Matteson, Kimberly Liang, et al.
(2015) Rheumatology, 54 p.433-440
Journal article

Association of exome sequences with plasma C-reactive protein levels in >9000 participants.

Ursula M Schick, Paul L Auer, Joshua C Bis, Honghuang Lin, Peng Wei, et al.
(2015) Human Molecular Genetics, 24 p.559-571
Journal article

Stable Peptide of the Endogenous Opioid Enkephalin Precursor and Breast Cancer Risk.

Olle Melander, Marju Orho-Melander, Jonas Manjer, Thomas Svensson, Peter Almgren, et al.
(2015) Journal of Clinical Oncology, 33 p.81-2632
Journal article

Duffy antigen receptor genetic variant and the association with Interleukin 8 levels.

Ilais Moreno Velásquez, Jitender Kumar, Harry Björkbacka, Jan Nilsson, Angela Silveira, et al.
(2015) Cytokine, 72 p.178-184
Journal article

Smoking and body mass index as risk factors for subtypes of cancer of unknown primary.

Kari Hemminki, Bowang Chen, Olle Melander, Jonas Manjer, Göran Hallmans, et al.
(2015) International Journal of Cancer, 136 p.246-247
Journal article (letter)

Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci.

Kyle J Gaulton, Teresa Ferreira, Yeji Lee, Anne Raimondo, Reedik Mägi, et al.
(2015) Nature Genetics, 47 p.1415-1415
Journal article

A genetic risk score for hypertension associates with the risk of ischemic stroke in a Swedish case-control study.

Cristiano Fava, Marketa Sjögren, Sandra Olsson, Håkan Lövkvist, Katarina Jood, et al.
(2015) European Journal of Human Genetics, 23 p.969-974
Journal article

Risk factors for the progression of carotid intima-media thickness over a 16-year follow-up period: The Malmö Diet and Cancer Study.

Maria Rosvall, Margaretha Persson, Gerd Östling, Peter Nilsson, Olle Melander, et al.
(2015) Atherosclerosis, 239 p.615-621
Journal article

Association between copeptin and declining glomerular filtration rate in people with newly diagnosed diabetes. The Skaraborg Diabetes Register.

Miriam Pikkemaat, Olle Melander, K Bengtsson Boström
(2015) Journal of Diabetes and its Complications, 29 p.1062-1065
Journal article

Expression Quantitative Trait Loci Acting Across Multiple Tissues Are Enriched in Inherited Risk for Coronary Artery Disease.

Hassan Foroughi Asl, Husain A Talukdar, Alida S D Kindt, Rajeev K Jain, Raili Ermel, et al.
(2015) Circulation: Cardiovascular Genetics, 8 p.305-305
Journal article

Vasopressin and hydration play a major role in the development of glucose intolerance and hepatic steatosis in obese rats

Christopher Taveau, Catherine Chollet, Ludovic Waeckel, Dorinne Desposito, Daniel G. Bichet, et al.
(2015) Diabetologia, 58 p.1081-1090
Journal article

Reflex syncope, anxiety level, and family history of cardiovascular disease in young women: case-control study.

D Zyśko, M Szewczuk-Bogusławska, M Kaczmarek, A K Agrawal, J Rudnicki, et al.
(2015) Europace, 17 p.309-313
Journal article

Low-Density Lipoprotein Particle Number Is Associated With Cardiovascular Events Among Those Not Classified Into Statin Benefit Groups

Olle Melander, Dov Shiffman, Michael P. Caulfield, Judy Z. Louie, Charles M. Rowland, et al.
(2015) Journal of the American College of Cardiology, 65 p.2571-2573
Journal article (letter)

Multiple anthropometric measures in relation to incidence of diabetes: a Swedish population-based cohort study.

Yan Borné, Peter Nilsson, Olle Melander, Bo Hedblad, Gunnar Engström
(2015) European Journal of Public Health, 25 p.1100-1105
Journal article

Higher levels of von Willebrand factor in patients with syncope due to orthostatic hypotension.

Nazim Isma, Richard Sutton, Andreas Hillarp, Karin Strandberg, Olle Melander, et al.
(2015) Journal of Hypertension, 33 p.1594-1601
Journal article

GWAS-identified loci for coronary heart disease are associated with intima-media thickness and plaque presence at the carotid artery bulb.

Marcel den Hoed, Rona J Strawbridge, Peter Almgren, Stefan Gustafsson, Tomas Axelsson, et al.
(2015) Atherosclerosis, 239 p.304-310
Journal article

High total carbon dioxide predicts 1-year readmission and death in patients with acute dyspnea.

Nathalie Lund, Anders Rohlén, Per Simonsson, Sofia Enhörning, Torgny Wessman, et al.
(2015) American Journal of Emergency Medicine, 33 p.1335-1339
Journal article

TET2 and CSMD1 genes affect SBP response to hydrochlorothiazide in never-treated essential hypertensives.

Martina Chittani, Roberta Zaninello, Chiara Lanzani, Francesca Frau, Maria F Ortu, et al.
(2015) Journal of Hypertension, 33 p.1301-1309
Journal article

C-peptide concentration, mortality and vascular complications in people with Type 2 diabetes. The Skaraborg Diabetes Register.

Miriam Pikkemaat, Olle Melander, Sigvard Mölstad, G Garberg, Kristina Bengtsson Boström
(2015) Diabetic Medicine, 32 p.85-89
Journal article

Non-hemodynamic predictors of arterial stiffness after 17 years of follow-up: the Malmö Diet and Cancer study.

Mikael Gottsäter, Gerd Östling, Margaretha Persson, Gunnar Engström, Olle Melander, et al.
(2015) Journal of Hypertension, 33 p.957-965
Journal article

New circulating biomarkers for predicting cardiovascular death in healthy population.

Olle Melander, Javier Modrego, Jose J Zamorano-León, Juana M Santos-Sancho, Vicente Lahera, et al.
(2015) Journal of Cellular and Molecular Medicine, 19 p.2489-2499
Journal article

Functional Analysis of a Carotid Intima-Media Thickness Locus Implicates BCAR1 and Suggests a Causal Variant.

Freya Boardman-Pretty, Andrew J P Smith, Jackie Cooper, Jutta Palmen, Lasse Folkersen, et al.
(2015) Circulation: Cardiovascular Genetics, 8 p.696-706
Journal article

The growth hormone receptor exon 3 deleted/full-length polymorphism is associated with central adiposity in the general population.

Camilla A M Glad, Lena M S Carlsson, Olle Melander, Peter Almgren, Lars Sjöström, et al.
(2015) European Journal of Endocrinology, 172
Journal article

1C.07: PRONEUROTENSIN INDEPENDENTLY PREDICTS CARDIOVASCULAR DISEASE. THE MALMÖ PREVENTIVE PROJECT.

Ayesha Fawad, C Schultz, P M Nilsson, Marju Orho-Melander, Olle Melander
(2015) Journal of Hypertension, 33 Suppl 1 p.11-11
Journal article

Soluble urokinase plasminogen activator receptor and incidence of venous thromboembolism.

Gunnar Engström, Bengt Zöller, Peter Svensson, Olle Melander, Margaretha Persson
(2015) Thrombosis and Haemostasis, 115 p.657-662
Journal article

1A.10: ASSOCIATION BETWEEN GENE POLYMORPHISMS AND RISK OF CARDIOVASCULAR EVENTS IN PATIENTS WITH CORONARY HEART DISEASE.

M Wirtwein, D Jarosz, K Polonis, M Hoffman, Olle Melander, et al.
(2015) Journal of Hypertension, 33 Suppl 1 p.3-3
Journal article

The Swedish CArdioPulmonary BioImage Study: objectives and design.

G Bergström, Göran Berglund, A Blomberg, J Brandberg, Gunnar Engström, et al.
(2015) Journal of Internal Medicine, 278 p.645-659
Journal article

A comprehensive 1000 Genomes-based genome-wide association meta-analysis of coronary artery disease

Majid Nikpay, Anuj Goel, Hong-Hee Won, Leanne M. Hall, Christina Willenborg, et al.
(2015) Nature Genetics, 47 p.1121-1121
Journal article

Atrial natriuretic Peptide and type 2 diabetes development - biomarker and genotype association study.

Amra Jujic, Peter Nilsson, Gunnar Engström, Bo Hedblad, Olle Melander, et al.
(2014) PLoS ONE, 9
Journal article

Common genetic determinants of lung function, subclinical atherosclerosis and risk of coronary artery disease.

Maria Sabater-Lleal, Anders Mälarstig, Lasse Folkersen, María Soler Artigas, Damiano Baldassarre, et al.
(2014) PLoS ONE, 9
Journal article

Smoking modifies the associated increased risk of future cardiovascular disease by genetic variation on chromosome 9p21.

Viktor Hamrefors, Bo Hedblad, George Hindy, Gustav Smith, Peter Almgren, et al.
(2014) PLoS ONE, 9
Journal article

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

Anubha Mahajan, Min Jin Go, Weihua Zhang, Jennifer E. Below, Kyle J. Gaulton, et al.
(2014) Nature Genetics, 46 p.234-234
Journal article

Loss-of-Function Mutations in APOC3, Triglycerides, and Coronary Disease

Jacy Crosby, Gina M. Peloso, Paul L. Auer, David R. Crosslin, Nathan O. Stitziel, et al.
(2014) New England Journal of Medicine, 371 p.22-31
Journal article

Response to letter to the editor 'Is red cell distribution width a biomarker in risk assessment of diabetes mellitus?

Gunnar Engström, Gustav Smith, Margaretha Persson, Peter Nilsson, Olle Melander, et al.
(2014) Journal of Internal Medicine, 276 p.538-538
Journal article (letter)

High salt intake increases copeptin but salt sensitivity is associated with fluid induced reduction of copeptin in women.

Irina Tasevska, Sofia Enhörning, Philippe Burri, Olle Melander
(2014) International Journal of Hypertension, 2014
Journal article

Red cell distribution width, haemoglobin A1c and incidence of diabetes mellitus.

Gunnar Engström, Gustav Smith, Margaretha Persson, Peter Nilsson, Olle Melander, et al.
(2014) Journal of Internal Medicine, 276 p.174-183
Journal article

The association between red cell distribution width and venous thromboembolism: A biochemical evaluation

Bengt Zöller, Olle Melander, Peter Svensson, Gunnar Engström
(2014) Thrombosis Research, 133 p.1164-1165
Journal article (letter)

Red cell distribution width in relation to incidence of coronary events and case fatality rates: a population-based cohort study.

Yan Borné, Gustav Smith, Olle Melander, Gunnar Engström
(2014) Heart, 100 p.1119-1124
Journal article

Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data.

Michael V Holmes, Caroline E Dale, Luisa Zuccolo, Richard J Silverwood, Yiran Guo, et al.
(2014) BMJ: British Medical Journal, 349 p.4164-4164
Journal article

Plasma cholesterol-induced lesion networks activated before regression of early, mature, and advanced atherosclerosis.

Johan L M Björkegren, Sara Hägg, Husain A Talukdar, Hassan Foroughi Asl, Rajeev K Jain, et al.
(2014) PLoS Genetics, 10
Journal article

Response to Letter to the Editor 'Red cell distribution width in patients with atrial fibrillation'

Samuel Adamsson Eryd, Yan Borné, Olle Melander, Margaretha Persson, Gustav Smith, et al.
(2014) Journal of Internal Medicine, 275 p.544-544
Journal article (letter)

Carotid intima-media thickness is associated with incidence of hospitalized atrial fibrillation.

Samuel Adamsson Eryd, Gerd Östling, Maria Rosvall, Margaretha Persson, Gustav Smith, et al.
(2014) Atherosclerosis, 233 p.673-678
Journal article

Lim Domain Binding 2: A Key Driver of Transendothelial Migration of Leukocytes and Atherosclerosis.

Ming-Mei Shang, Husain A Talukdar, Jennifer J Hofmann, Colin Niaudet, Hassan Foroughi Asl, et al.
(2014) Arteriosclerosis, Thrombosis and Vascular Biology, 34 p.2068-2077
Journal article

The presence of pacing artifacts may impede diagnosis of ventricular fibrillation during cardiac arrest.

Timler Dariusz, D Zyśko, Koźluk Edward, Piątkowska Agnieszka, Grzebieniak Tomasz, et al.
(2014) Resuscitation, 85 p.167-168
Journal article (letter)

Gene-centric meta-analyses for central adiposity traits in up to 57 412 individuals of European descent confirm known loci and reveal several novel associations

Sachiko Yoneyama, Yiran Guo, Matthew B. Lanktree, Michael R. Barnes, Clara C. Elbers, et al.
(2014) Human Molecular Genetics, 23 p.2498-2510
Journal article

Soluble Urokinase Plasminogen Activator Receptor: A Risk Factor for Carotid Plaque, Stroke, and Coronary Artery Disease.

Margaretha Persson, Gerd Östling, Gustav Smith, Viktor Hamrefors, Olle Melander, et al.
(2014) Stroke: a journal of cerebral circulation, 45 p.18-23
Journal article

Increased plasma level of soluble urokinase plasminogen activator receptor is associated with incidence of heart failure but not atrial fibrillation.

Yan Borné, Margaretha Persson, Olle Melander, Gustav Smith, Gunnar Engström
(2014) European Journal of Heart Failure, 16 p.377-383
Journal article

Red blood cell distribution width is associated with incidence of atrial fibrillation.

Samuel Adamsson Eryd, Yan Borné, Olle Melander, M Persson, Gustav Smith, et al.
(2014) Journal of Internal Medicine, 275 p.84-92
Journal article

Multiple Associated Variants Increase the Heritability Explained for Plasma Lipids and Coronary Artery Disease.

Hayato Tada, Hong-Hee Won, Olle Melander, Jian Yang, Gina M Peloso, et al.
(2014) Circulation: Cardiovascular Genetics, 7 p.583-587
Journal article

Ceruloplasmin and atrial fibrillation: evidence of causality from a population-based Mendelian randomization study.

Samuel Adamsson Eryd, Marketa Sjögren, Gustav Smith, Peter Nilsson, Olle Melander, et al.
(2014) Journal of Internal Medicine, 275 p.164-171
Journal article

Genetic variation in NEDD4L, salt sensitivity, and hypertension: human NEDD4L rs4149601 G allele generates evolutionary new isoform I with C2 domain.

Jonas Dahlberg, Olle Melander
(2014) Journal of Hypertension, 32 p.1905-1906
Journal article (letter)

Impaired Fibrous Repair: A Possible Contributor to Atherosclerotic Plaque Vulnerability in Patients With Type II Diabetes.

Andreas Edsfeldt, Isabel Goncalves, Helena Grufman, Mihaela Nitulescu, Pontus Dunér, et al.
(2014) Arteriosclerosis, Thrombosis and Vascular Biology, 34 p.2143-2150
Journal article

Evaluation of pre-arrest morbidity score and prognosis after resuscitation score and other clinical variables associated with in-hospital cardiac arrest in southern Sweden.

Marcus Ohlsson, Linn Kennedy, Tord Juhlin, Olle Melander
(2014) Resuscitation, 85 p.1370-1374
Journal article

Plasma Natriuretic Peptides and Incidence of Subtypes of Ischemic Stroke.

John Berntsson, Elisabet Zia, Yan Borné, Olle Melander, Bo Hedblad, et al.
(2014) Cerebrovascular Diseases, 37 p.444-450
Journal article

Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks.

Gina M Peloso, Paul L Auer, Joshua C Bis, Arend Voorman, Alanna C Morrison, et al.
(2014) American Journal of Human Genetics, 94 p.223-232
Journal article

History of syncope predicts loss of consciousness after head trauma: Retrospective study

Dorota Zysko, Richard Sutton, Dariusz Timler, Stanislaw Furtan, Olle Melander, et al.
(2014) Cardiology Journal, 21 p.674-678
Journal article

Twelve-Single Nucleotide Polymorphism Genetic Risk Score Identifies Individuals at Increased Risk for Future Atrial Fibrillation and Stroke.

Hayato Tada, Dov Shiffman, Gustav Smith, Marketa Sjögren, Steven A Lubitz, et al.
(2014) Stroke: a journal of cerebral circulation, 45 p.2856-2856
Journal article

Pathogenic Ischemic Stroke Phenotypes in the NINDS-Stroke Genetics Network.

Hakan Ay, Ethem Murat Arsava, Gunnar Andsberg, Thomas Benner, Robert D Brown, et al.
(2014) Stroke: a journal of cerebral circulation, 45 p.3589-3596
Journal article

Genetic variation in NEDD4L, an epithelial sodium channel regulator, is associated with cardiovascular disease and cardiovascular death.

Jonas Dahlberg, Marketa Sjögren, Bo Hedblad, Gunnar Engström, Olle Melander
(2014) Journal of Hypertension, 32 p.294-299
Journal article

Family History of Myocardial Infarction Increases Risk of Renal Dysfunction in Middle Age.

Anders Christensson, Olle Melander, Erik Fjellstedt, Maria Ohlson Andersson
(2014) American Journal of Nephrology, 39 p.85-91
Journal article

Carotid plaque, intima-media thickness, and incident aortic stenosis: a prospective cohort study.

Andreas Martinsson, Gerd Östling, Margaretha Persson, Kristina Sundquist, Charlotte Andersson, et al.
(2014) Arteriosclerosis, Thrombosis and Vascular Biology, 34 p.2343-2343
Journal article

Integrating Genetic, Transcriptional, and Functional Analyses to Identify Five Novel Genes for Atrial Fibrillation.

Moritz F Sinner, Nathan R Tucker, Kathryn L Lunetta, Kouichi Ozaki, Gustav Smith, et al.
(2014) Circulation, 130 p.1225-1225
Journal article

Red cell distribution width and risk for venous thromboembolism: A population-based cohort study.

Bengt Zöller, Olle Melander, Peter Svensson, Gunnar Engström
(2014) Thrombosis Research, 133 p.334-339
Journal article

Fasting levels of high-sensitivity growth hormone predict cardiovascular morbidity and mortality: the malmö diet and cancer study.

Erik Hallengren, Peter Almgren, Gunnar Engström, Bo Hedblad, Margaretha Persson, et al.
(2014) Journal of the American College of Cardiology, 64 p.1452-1460
Journal article

Cardiovascular consequences of a polygenetic component of blood pressure in an urban-based longitudinal study: the Malmö Diet and Cancer.

Cristiano Fava, Therese Ohlsson, Marketa Sjögren, Angela Tagetti, Peter Almgren, et al.
(2014) Journal of Hypertension, 32 p.1424-1428
Journal article

Validation of plasma proneurotensin as a novel biomarker for the prediction of incident breast cancer.

Olle Melander, Mattias Belting, Jonas Manjer, Alan S Maisel, Bo Hedblad, et al.
(2014) Cancer Epidemiology Biomarkers & Prevention, 23 p.1672-1676
Journal article

Genetic Determinants of Long-Term Changes in Blood Lipid Concentrations: 10-Year Follow-Up of the GLACIER Study.

Tibor V Varga, Emily Sonestedt, Dmitry Shungin, Robert Koivula, Göran Hallmans, et al.
(2014) PLoS Genetics, 10
Journal article

Meta-analysis of gene-level tests for rare variant association.

Dajiang J Liu, Gina M Peloso, Xiaowei Zhan, Oddgeir L Holmen, Matthew Zawistowski, et al.
(2014) Nature Genetics, 46 p.200-200
Journal article

Cystatin C identifies cardiovascular risk better than creatinine-based estimates of glomerular filtration in middle-aged individuals without a history of cardiovascular disease.

Patrik Svensson, Maria Ohlson Andersson, Peter Almgren, Bo Hedblad, Gunnar Engström, et al.
(2014) Journal of Internal Medicine, 275 p.506-521
Journal article

Gene-centric Meta-analysis in 87,736 Individuals of European Ancestry Identifies Multiple Blood-Pressure-Related Loci.

Vinicius Tragante, Michael R Barnes, Santhi K Ganesh, Matthew B Lanktree, Wei Guo, et al.
(2014) American Journal of Human Genetics, 94 p.349-360
Journal article

Systolic and diastolic component of orthostatic hypotension and cardiovascular events in hypertensive patients: the Captopril Prevention Project.

Artur Fedorowski, Björn Wahlstrand, Thomas Hedner, Olle Melander
(2014) Journal of Hypertension, 32 p.75-81
Journal article

The chromosome 9p21 variant interacts with vegetable and wine intake to influence the risk of cardiovascular disease : a population based cohort study

George Hindy, Ulrika Ericson, Viktor Hamrefors, Isabel Drake, Elisabet Wirfält, et al.
(2014) BMC Medical Genetics, 15
Journal article

PP038. Renal ETK/BMX activation decreased in preeclampsia

Helena Strevens, Dag Wide-Swensson, Ola Hansson, Olle Melander
(2013) Pregnancy Hypertension, 3 p.80-80
Journal article

Renässans för klortalidon

Arne Melander, Olle Melander
(2013) Läkartidningen, 110
Journal article (letter)

Mild Renal Dysfunction and Metabolites Tied to Low HDL Cholesterol Are Associated With Monocytosis and Atherosclerosis

Anjali Ganda, Martin Magnusson, Laurent Yvan-Charvet, Bo Hedblad, Gunnar Engström, et al.
(2013) Circulation, 127 p.988-996
Journal article

Large-scale association analysis identifies new risk loci for coronary artery disease

Panos Deloukas, Stavroula Kanoni, Christina Willenborg, Martin Farrall, Themistocles L. Assimes, et al.
(2013) Nature Genetics, 45 p.25-33
Journal article

Vasovagal Syncope Related to Emotional Stress Predicts Coronary Events in Later Life

Dorota Zysko, Olle Melander, Artur Fedorowski
(2013) PACE, 36 p.1000-1006
Journal article

A genetic variant of the atrial natriuretic peptide gene is associated with left ventricular hypertrophy in a non-diabetic population - the Malmo preventive project study

Amra Jujic, Margrét Leosdottir, Gerd Östling, Petri Gudmundsson, Peter Nilsson, et al.
(2013) BMC Medical Genetics, 14
Journal article

Genetic Variants of Coagulation Factor XI Show Association with Ischemic Stroke Up to 70 Years of Age

Ellen Hanson, Staffan Nilsson, Katarina Jood, Bo Norrving, Gunnar Engström, et al.
(2013) PLoS ONE, 8
Journal article

Hypertension and Genetic Variation in Endothelial-Specific Genes

Erik Larsson, Bjorn Wahlstrand, Bo Hedblad, Thomas Hedner, Sverre E. Kjeldsen, et al.
(2013) PLoS ONE, 8
Journal article

Plasma lipid composition and risk of developing cardiovascular disease.

Celine Fernandez, Marianne Sandin, Julio L Sampaio, Peter Almgren, Krzysztof Narkiewicz, et al.
(2013) PLoS ONE, 8
Journal article

Plasma procalcitonin is associated with all-cause and cancer mortality in apparently healthy men: a prospective population-based study.

Ovidiu Cotoi, Jonas Manjer, Bo Hedblad, Gunnar Engström, Olle Melander, et al.
(2013) BMC Medicine, 11
Journal article

Novel cardiovascular biomarkers in unexplained syncopal attacks: the SYSTEMA cohort.

Artur Fedorowski, Philippe Burri, J Struck, Steen Juul-Möller, Olle Melander
(2013) Journal of Internal Medicine, 273 p.359-367
Journal article

Pharmacogenomic Association of Nonsynonymous SNPs in SIGLEC12, A1BG, and the Selectin Region and Cardiovascular Outcomes

Caitrin W. McDonough, Yan Gong, Sandosh Padmanabhan, Ben Burkley, Taimour Y. Langaee, et al.
(2013) Hypertension, 62 p.48-54
Journal article

Common Polymorphisms in the CYP11B1 and CYP11B2 Genes: Evidence for a Digenic Influence on Hypertension

Samantha Alvarez-Madrazo, Scott M. MacKenzie, Eleanor Davies, Robert Fraser, Wai-Kwong Lee, et al.
(2013) Hypertension, 61 p.232-239
Journal article

Genetic polymorphisms confer risk of atrial fibrillation in patients with heart failure: a population-based study.

Gustav Smith, Olle Melander, Marketa Sjögren, Bo Hedblad, Gunnar Engström, et al.
(2013) European Journal of Heart Failure, 15 p.250-257
Journal article

Telomeres and cardiovascular disease risk: an update 2013.

Peter Nilsson, Hanna Tufvesson, Margrét Leosdottir, Olle Melander
(2013) Translational Research, 162 p.371-380
Journal article

High levels of cystatin C predict the metabolic syndrome: the prospective Malmö Diet and Cancer Study.

Martin Magnusson, Bo Hedblad, Gunnar Engström, Magnus Persson, Peter Nilsson, et al.
(2013) Journal of Internal Medicine, 274 p.192-199
Journal article

Genetic Associations with Valvular Calcification and Aortic Stenosis

George Thanassoulis, Catherine Y. Campbell, David S. Owens, Gustav Smith, Albert V. Smith, et al.
(2013) New England Journal of Medicine, 368 p.503-512
Journal article

Syndromes of orthostatic intolerance: a hidden danger.

Artur Fedorowski, Olle Melander
(2013) Journal of Internal Medicine, 273 p.322-335
Journal article review

Genomic Association Analysis of Common Variants Influencing Antihypertensive Response to Hydrochlorothiazide

Stephen T. Turner, Eric Boerwinkle, Jeffrey R. O'Connell, Kent R. Bailey, Yan Gong, et al.
(2013) Hypertension, 62 p.391-397
Journal article

Diabetes Mellitus and Elevated Copeptin Levels in Middle Age Predict Low Cognitive Speed after Long-Term Follow-Up.

Eva Tufvesson, Olle Melander, Lennart Minthon, Margaretha Persson, Peter Nilsson, et al.
(2013) Dementia and Geriatric Cognitive Disorders, 35 p.67-76
Journal article

Loci influencing blood pressure identified using a cardiovascular gene-centric array

Santhi K. Ganesh, Vinicius Tragante, Wei Guo, Yiran Guo, Matthew B. Lanktree, et al.
(2013) Human Molecular Genetics, 22 p.1663-1678
Journal article

Serum biomarkers and clinical outcomes in heart failure patients treated de novo with carvedilol

Jadwiga Nessler, Bohdan Nessler, Renata Golebiowska-Wiatrak, Ilona Palka, Andrzej Gackowski, et al.
(2013) Cardiology Journal, 20 p.144-151
Journal article

Are 25 SNPs from the CARDIoGRAM study associated with ischaemic stroke?

Håkan Lövkvist, Marketa Sjögren, Peter Höglund, Gunnar Engström, C Jern, et al.
(2013) European Journal of Neurology, 20 p.1284-1291
Journal article

Genetic susceptibility to obesity and diet intakes: association and interaction analyses in the Malmö Diet and Cancer Study.

Gull Rukh, Emily Sonestedt, Olle Melander, Bo Hedblad, Elisabet Wirfält, et al.
(2013) Genes & Nutrition, 8 p.535-547
Journal article

Adrenomedullin is a marker of carotid plaques and intima-media thickness as well as brachial pulse pressure.

Mikael Gottsäter, Lisa Bellinetto-Ford, Gerd Östling, Magaretha Persson, Peter Nilsson, et al.
(2013) Journal of Hypertension, 31 p.1959-1965
Journal article

Smoking and obesity associated BDNF gene variance predicts total and cardiovascular mortality in smokers.

Sara Halldén, Marketa Sjögren, Bo Hedblad, Gunnar Engström, Krzysztof Narkiewicz, et al.
(2013) Heart, 99 p.949-953
Journal article

A diabetes-predictive amino acid score and future cardiovascular disease.

Martin Magnusson, Gregory D Lewis, Ulrika Ericson, Marju Orho-Melander, Bo Hedblad, et al.
(2013) European Heart Journal, 34 p.1982-1989
Journal article

Response to letter to the editor 'Serum cystatin-C levels correlate with endothelial dysfunction in patients with the metabolic syndrome'

Martin Magnusson, Bo Hedblad, Gunnar Engström, Maria Persson, Peter Nilsson, et al.
(2013) Journal of Internal Medicine, 274 p.496-498
Journal article (letter)

Exome Sequencing and Directed Clinical Phenotyping Diagnose Cholesterol Ester Storage Disease Presenting as Autosomal Recessive Hypercholesterolemia.

Nathan O Stitziel, Sigrid W Fouchier, Barbara Sjouke, Gina M Peloso, Alessa M Moscoso, et al.
(2013) Arteriosclerosis, Thrombosis and Vascular Biology, 33 p.2909-2914
Journal article

Copeptin, a marker of vasopressin, in abdominal obesity, diabetes and microalbuminuria: the prospective Malmö Diet and Cancer Study cardiovascular cohort.

Sofia Enhörning, L Bankir, N Bouby, J Struck, Bo Hedblad, et al.
(2013) International Journal of Obesity, 37 p.598-603
Journal article

The Dark Side of the Swoon: antihypertensive treatment in the elderly.

Artur Fedorowski, Steen Juul-Möller, Olle Melander
(2013) Journal of Internal Medicine, 274 p.293-294
Journal article (letter)

Novel and established anthropometric measures and the prediction of incident cardiovascular disease: a cohort study

A. C. Carlsson, U. Riserus, Gunnar Engström, J. Arnlov, O. Melander, et al.
(2013) International Journal of Obesity, 37 p.1579-1585
Journal article

Chromosome 9p21 genetic variation explains 13% of cardiovascular disease incidence but does not improve risk prediction.

Klas Gränsbo, Peter Almgren, Marketa Sjögren, Garrett Smith, Gunnar Engström, et al.
(2013) Journal of Internal Medicine, 274 p.233-240
Journal article

2-Aminoadipic acid is a biomarker for diabetes risk

Thomas J. Wang, Debby Ngo, Nikolaos Psychogios, Andre Dejam, Martin G. Larson, et al.
(2013) Journal of Clinical Investigation, 123 p.4309-4317
Journal article

Prediction of Blood Pressure Changes Over Time and Incidence of Hypertension by a Genetic Risk Score in Swedes.

Cristiano Fava, Marketa Sjögren, Martina Montagnana, Elisa Danese, Peter Almgren, et al.
(2012) Hypertension
Journal article

Epidemiology and characteristics of hyponatremia in the emergency department.

Karin Olsson, Bertil Öhlin, Olle Melander
(2012) European Journal of Internal Medicine
Journal article

Genetic polymorphisms for estimating risk of atrial fibrillation: a literature-based meta-analysis.

Gustav Smith, Peter Almgren, Gunnar Engström, Bo Hedblad, Pyotr Platonov, et al.
(2012) Journal of Internal Medicine
Journal article

The Renalase Asp37Glu polymorphism is not associated with hypertension and cardiovascular events in an urban-based prospective cohort: the Malmo Diet and cancer study

Cristiano Fava, Martina Montagnana, Elisa Danese, Marketa Sjögren, Peter Almgren, et al.
(2012) BMC Medical Genetics, 13
Journal article

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

Andrew P. Morris, Benjamin F. Voight, Tanya M. Teslovich, Teresa Ferreira, Ayellet V. Segre, et al.
(2012) Nature Genetics, 44 p.981-981
Journal article

Genetic variation in PNPLA3 but not APOC3 influences liver fat in non-alcoholic fatty liver disease

Jenni Hyysalo, Ivana Stojkovic, Anna Kotronen, Antti Hakkarainen, Ksenia Sevastianova, et al.
(2012) Journal of Gastroenterology and Hepatology, 27 p.951-956
Journal article

Meta-analysis identifies six new susceptibility loci for atrial fibrillation

Patrick T. Ellinor, Kathryn L. Lunetta, Christine M. Albert, Nicole L. Glazer, Marylyn D. Ritchie, et al.
(2012) Nature Genetics, 44 p.88-670
Journal article

Low Plasma Level of Atrial Natriuretic Peptide Predicts Development of Diabetes: The Prospective Malmo Diet and Cancer Study.

Martin Magnusson, Amra Jujic, Bo Hedblad, Gunnar Engström, Margaretha Persson, et al.
(2012) The Journal of clinical endocrinology and metabolism, 97 p.638-645
Journal article

Hypertension, cardiovascular risk and polymorphisms in genes controlling the cytochrome P450 pathway of arachidonic acid: A sex-specific relation?

Cristiano Fava, Marco Ricci, Olle Melander, Pietro Minuz
(2012) Prostaglandins & other Lipid Mediators, 98 p.75-85
Journal article

Metabolite Profiling Identifies Pathways Associated With Metabolic Risk in Humans

Susan Cheng, Eugene P. Rhee, Martin G. Larson, Gregory D. Lewis, Elizabeth L. McCabe, et al.
(2012) Circulation, 125 p.132-2222
Journal article

Genetic Variation Within the Interleukin-1 Gene Cluster and Ischemic Stroke

Sandra Olsson, Lukas Holmegaard, Katarina Jood, Marketa Sjögren, Gunnar Engström, et al.
(2012) Stroke: a journal of cerebral circulation, 43 p.2278-2278
Journal article

Large-Scale Gene-Centric Meta-Analysis across 39 Studies Identifies Type 2 Diabetes Loci

Richa Saxena, Clara C. Elbers, Yiran Guo, Inga Peter, Tom R. Gaunt, et al.
(2012) American Journal of Human Genetics, 90 p.410-425
Journal article

Seventy-five genetic loci influencing the human red blood cell

Pim van der Harst, Weihua Zhang, Irene Mateo Leach, Augusto Rendon, Niek Verweij, et al.
(2012) Nature, 492 p.369-375
Journal article

From circulating biomarkers to genomics and imaging in the prediction of cardiovascular events in the general population.

Cristiano Fava, Martina Montagnana, Gian Cesare Guidi, Olle Melander
(2012) Annals of Medicine, 44 p.433-447
Journal article

Large-Scale Gene-Centric Meta-analysis across 32 Studies Identifies Multiple Lipid Loci

Folkert W. Asselbergs, Yiran Guo, Erik P. A. van Iperen, Suthesh Sivapalaratnam, Vinicius Tragante, et al.
(2012) American Journal of Human Genetics, 91 p.823-838
Journal article

Total and differential leucocyte counts in relation to incidence of stroke subtypes and mortality: a prospective cohort study

Elisabet Zia, Olle Melander, Harry Björkbacka, Bo Hedblad, Gunnar Engström
(2012) Journal of Internal Medicine, 272 p.298-304
Journal article

Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study

Benjamin F. Voight, Gina M. Peloso, Marju Orho-Melander, Ruth Frikke-Schmidt, Maja Barbalic, et al.
(2012) The Lancet, 380 p.572-580
Journal article

Alcohol consumption and mortality in individuals with diabetes mellitus

Diewertje Sluik, Heiner Boeing, Manuela M. Bergmann, Madlen Schuetze, Birgit Teucher, et al.
(2012) British Journal of Nutrition, 108 p.1307-1315
Journal article

TFPI gene variation and ischemic stroke

Annie Pedersen, Ellen Hanson, Sandra Olsson, Tara M. Stanne, Christian Blomstrand, et al.
(2012) Thrombosis Research, 130 p.565-567
Journal article (letter)

Genomewide Association Study Using a High-Density Single Nucleotide Polymorphism Array and Case-Control Design Identifies a Novel Essential Hypertension Susceptibility Locus in the Promoter Region of Endothelial NO Synthase.

Erika Salvi, Zoltán Kutalik, Nicola Glorioso, Paola Benaglio, Francesca Frau, et al.
(2012) Hypertension, 59 p.248-248
Journal article

Genetic Polymorphisms for Estimating Risk of Atrial Fibrillation in the General Population: A Prospective Study

J. Gustav Smith, Christopher Newton-Cheh, Peter Almgren, Olle Melander, Pyotr Platonov
(2012) Archives of Internal Medicine, 172 p.742-744
Journal article (letter)

Identification of the BCAR1-CFDP1-TMEM170A Locus as a Determinant of Carotid Intima-Media Thickness and Coronary Artery Disease Risk

Karl Gertow, Bengt Sennblad, Rona J. Strawbridge, John Oehrvik, Delilah Zabaneh, et al.
(2012) Circulation: Cardiovascular Genetics, 5 p.656-665
Journal article

Association of central and peripheral pulse pressure with intermediate cardiovascular phenoytpes.

Ulf Neisius, Grzegorz Bilo, Chiara Taurino, John D McClure, Markus P Schneider, et al.
(2012) Journal of Hypertension, 30 p.67-74
Journal article

A large-sample assessment of possible association between ischaemic stroke and rs12188950 in the PDE4D gene.

Håkan Lövkvist, Sandra Olsson, Peter Höglund, Olle Melander, Christina Jern, et al.
(2012) European Journal of Human Genetics, 20 p.783-789
Journal article

Incidence of Coronary Events and Case Fatality Rate in Relation to Blood Lymphocyte and Neutrophil Counts.

Samuel Adamsson Eryd, Gustav Smith, Olle Melander, Bo Hedblad, Gunnar Engström
(2012) Arteriosclerosis, Thrombosis and Vascular Biology, 32 p.533-837
Journal article

A Common Missense Variant in the ATP Receptor P2X7 Is Associated with Reduced Risk of Cardiovascular Events.

Olof Gidlöf, Gustav Smith, Olle Melander, Håkan Lövkvist, Bo Hedblad, et al.
(2012) PLoS ONE, 7
Journal article

Orthostatic blood pressure response, carotid intima-media thickness, and plasma fibrinogen in older nondiabetic adults.

Artur Fedorowski, Gerd Östling, Margaretha Persson, Joachim Struck, Gunnar Engström, et al.
(2012) Journal of Hypertension, 30 p.522-529
Journal article

The functional variant V433M of the CYP4F2 and the metabolic syndrome in Swedes.

Cristiano Fava, Martina Montagnana, Elisa Danese, Marketa Sjögren, Peter Almgren, et al.
(2012) Prostaglandins & other Lipid Mediators, 98 p.31-36
Journal article

Plasma procalcitonin and the risk of cardiovascular events and death: a prospective population-based study.

Alexandru Schiopu, Bo Hedblad, Gunnar Engström, Joachim Struck, Nils G Morgenthaler, et al.
(2012) Journal of Internal Medicine, 272 p.484-491
Journal article

A myocardial infarction genetic risk score is associated with markers of carotid atherosclerosis.

Viktor Hamrefors, Bo Hedblad, Gunnar Engström, Peter Almgren, Marketa Sjögren, et al.
(2012) Journal of Internal Medicine, 271 p.271-281
Journal article

Pharmacogenetic implications for eight common blood pressure-associated single-nucleotide polymorphisms.

Viktor Hamrefors, Marketa Sjögren, Peter Almgren, Björn Wahlstrand, Sverre Kjeldsen, et al.
(2012) Journal of Hypertension, 30 p.1151-1160
Journal article

Vasoactive Peptides with Angiogenesis-Regulating Activity Predict Cancer Risk in Males.

Mattias Belting, Peter Almgren, Jonas Manjer, Bo Hedblad, Joachim Struck, et al.
(2012) Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 21 p.513-522
Journal article

A clinically confirmed family history for early myocardial infarction is associated with increased risk of obesity, insulin resistance and metabolic syndrome.

Martin Magnusson, Philippe Burri, Olle Melander
(2012) Journal of Hypertension, 30 p.948-953
Journal article

Orthostatic hypotension and novel blood pressure-associated gene variants: Genetics of Postural Hemodynamics (GPH) Consortium.

Artur Fedorowski, Nora Franceschini, Jennifer Brody, Chunyu Liu, Germaine C Verwoert, et al.
(2012) European Heart Journal, 33 p.2331-2341
Journal article

Plasma proneurotensin and incidence of diabetes, cardiovascular disease, breast cancer, and mortality.

Olle Melander, Alan S Maisel, Peter Almgren, Jonas Manjer, Mattias Belting, et al.
(2012) JAMA: The Journal of the American Medical Association, 308 p.1469-1475
Journal article

Hypothesis-Based Analysis of Gene-Gene Interactions and Risk of Myocardial Infarction

Gavin Lucas, Carla Lluis-Ganella, Isaac Subirana, Muntaser D. Musameh, Juan Ramon Gonzalez, et al.
(2012) PLoS ONE, 7
Journal article

Vanin-1 T26I polymorphism, hypertension and cardiovascular events in two large urban-based prospective studies in Swedes.

Cristiano Fava, Martina Montagnana, E Danese, Marketa Sjögren, Peter Almgren, et al.
(2011) Nutrition Metabolism and Cardiovascular Diseases
Journal article

Nyheter inom kardiovaskulär genetik öppnar för nya terapimöjligheter

Peter M. Nilsson, Marju Orho-Melander, Olle Melander
(2011) Läkartidningen, 108 p.540-543
Journal article

Genetic Variant on Chromosome 12p13 Does Not Show Association to Ischemic Stroke in 3 Swedish Case-Control Studies

Sandra Olsson, Olle Melander, Katarina Jood, Gustav Smith, Håkan Lövkvist, et al.
(2011) Stroke: a journal of cerebral circulation, 42 p.214-216
Journal article

Metabolite profiles and the risk of developing diabetes

Thomas J. Wang, Martin G. Larson, Ramachandran S. Vasan, Susan Cheng, Eugene P. Rhee, et al.
(2011) Nature Medicine, 17 p.83-448
Journal article

Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease

Heribert Schunkert, Inke R. Koenig, Sekar Kathiresan, Muredach P. Reilly, Themistocles L. Assimes, et al.
(2011) Nature Genetics, 43 p.153-333
Journal article

A functional variant of the NEDD4L gene is associated with beneficial treatment response with β-blockers and diuretics in hypertensive patients.

Patrik Svensson, Björn Wahlstrand, Peter Almgren, Jonas Dahlberg, Cristiano Fava, et al.
(2011) Journal of Hypertension, 29 p.388-395
Journal article

FTO, Type 2 Diabetes, and Weight Gain Throughout Adult Life A Meta-Analysis of 41,504 Subjects From the Scandinavian HUNT, MDC, and MPP Studies

Jens K. Hertel, Stefan Johansson, Emily Sonestedt, Anna Jonsson, Rolv T. Lie, et al.
(2011) Diabetes, 60 p.1637-1644
Journal article

Fruit and vegetable intake and mortality from ischaemic heart disease: results from the European Prospective Investigation into Cancer and Nutrition (EPIC)-Heart study

Francesca L. Crowe, Andrew W. Roddam, Timothy J. Key, Paul N. Appleby, Kim Overvad, et al.
(2011) European Heart Journal, 32 p.1235-1243
Journal article

Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure

Louise V. Wain, Germaine C. Verwoert, Paul F. O'Reilly, Gang Shi, Toby Johnson, et al.
(2011) Nature Genetics, 43 p.122-1005
Journal article

Power in the Phenotypic Extremes: A Simulation Study of Power in Discovery and Replication of Rare Variants

Lin T. Guey, Jasmina Kravic, Olle Melander, Noel P. Burtt, Jason M. Laramie, et al.
(2011) Genetic Epidemiology, 35 p.236-246
Journal article

A Variant Upstream of the CDH13 Adiponectin Receptor Gene and Metabolic Syndrome in Swedes.

Cristiano Fava, Elisa Danese, Martina Montagnana, Marketa Sjögren, Peter Almgren, et al.
(2011) American Journal of Cardiology, 108 p.1432-1437
Journal article

Red cell distribution width and risk for first hospitalization due to heart failure: a population-based cohort study.

Yan Borné, Gustav Smith, Olle Melander, Bo Hedblad, Gunnar Engström
(2011) European Journal of Heart Failure, 13 p.1355-1361
Journal article

Post-Genomic Update on a Classical Candidate Gene for Coronary Artery Disease: ESR1

Gavin Lucas, Carla Lluis-Ganella, Isaac Subirana, Mariano Senti, Christina Willenborg, et al.
(2011) Circulation: Cardiovascular Genetics, 4 p.357-647
Journal article

Directionality of blood pressure response to standing may determine development of heart failure: prospective cohort study.

Artur Fedorowski, Bo Hedblad, Gunnar Engström, Olle Melander
(2011) European Journal of Heart Failure, 13 p.496-503
Journal article

Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height

Matthew B. Lanktree, Yiran Guo, Muhammed Murtaza, Joseph T. Glessner, Swneke D. Bailey, et al.
(2011) American Journal of Human Genetics, 88 p.41443-41443
Journal article

A Genome-Wide Association Study Identifies LIPA as a Susceptibility Gene for Coronary Artery Disease

Philipp S. Wild, Tanja Zeller, Arne Schillert, Silke Szymczak, Christoph R. Sinning, et al.
(2011) Circulation: Cardiovascular Genetics, 4 p.203-403
Journal article

Inflammation-sensitive proteins and risk of atrial fibrillation: a population-based cohort study.

Samuel Adamsson Eryd, Gustav Smith, Olle Melander, Bo Hedblad, Gunnar Engström
(2011) European Journal of Epidemiology, 26 p.449-455
Journal article

Blood Pressure Loci Identified with a Gene-Centric Array

Toby Johnson, Tom R. Gaunt, Stephen J. Newhouse, Sandosh Padmanabhan, Maciej Tomaszewski, et al.
(2011) American Journal of Human Genetics, 89 p.688-700
Journal article

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

Georg B. Ehret, Patricia B. Munroe, Kenneth M. Rice, Murielle Bochud, Andrew D. Johnson, et al.
(2011) Nature, 478 p.103-109
Journal article

Lack of association between genetic variations in the KALRN region and ischemic stroke

Sandra Olsson, Katarina Jood, Olle Melander, Marketa Sjögren, Bo Norrving, et al.
(2011) Clinical Biochemistry, 44 p.1018-1020
Journal article

Early postural blood pressure response and cause-specific mortality among middle-aged adults: what is the role of diastolic blood pressure? Reply

Artur Fedorowski, Olle Melander
(2011) European Journal of Epidemiology, 26 p.894-894
Journal article (comment)

Early postural blood pressure response and cause-specific mortality among middle-aged adults.

Artur Fedorowski, Bo Hedblad, Olle Melander
(2011) European Journal of Epidemiology, 26 p.537-546
Journal article

Uromodulin gene variant is associated with type 2 diabetic nephropathy.

Tarunveer S Ahluwalia, Eero Lindholm, Leif Groop, Olle Melander
(2011) Journal of Hypertension, 29 p.1731-1734
Journal article

Serine/threonine kinase 39 is a candidate gene for primary hypertension especially in women: results from two cohort studies in Swedes.

Cristiano Fava, Elisa Danese, Martina Montagnana, Marketa Sjögren, Peter Almgren, et al.
(2011) Journal of Hypertension, 29 p.484-491
Journal article

Plasma Copeptin, A Unifying Factor behind the Metabolic Syndrome.

Sofia Enhörning, Joachim Struck, Elisabet Wirfält, Bo Hedblad, Nils G Morgenthaler, et al.
(2011) The Journal of clinical endocrinology and metabolism, 96 p.1065-1072
Journal article

Age and gender differences in the association between Nt-proBNP and glucometabolic disturbances.

Margrét Leosdottir, Ronnie Willenheimer, Christian Hall, Solve Tjora, Johan Malm, et al.
(2011) Scandinavian cardiovascular journal : SCJ, 45 p.294-300
Journal article

Genetic variants in serum and glucocortocoid regulated kinase 1, a regulator of the epithelial sodium channel, are associated with ischaemic stroke.

Jonas Dahlberg, Gustav Smith, Bo Norrving, Peter Nilsson, Bo Hedblad, et al.
(2011) Journal of Hypertension, 29 p.884-889
Journal article

Salt-inducible kinase 1 influences Na+,K+-ATPase activity in vascular smooth muscle cells and associates with variations in blood pressure.

Sergej Popov, Angela Silveira, Dick Wågsäter, Hiroshi Takemori, Ryousuke Oguro, et al.
(2011) Journal of Hypertension, 29 p.2395-2403
Journal article

Increased risk of atrial fibrillation in patients with coeliac disease: a nationwide cohort study

Louise Emilsson, Gustav Smith, Joe West, Olle Melander, Jonas F. Ludvigsson
(2011) European Heart Journal, 32 p.2430-2437
Journal article

Cardiac Natriuretic Peptides, Obesity, and Insulin Resistance: Evidence from Two Community-Based Studies.

Abigail May Khan, Susan Cheng, Martin Magnusson, Martin G Larson, Christopher Newton-Cheh, et al.
(2011) The Journal of clinical endocrinology and metabolism, 96 p.3242-3249
Journal article

Pleiotropic Effects of GIP on Islet Function Involve Osteopontin

Valeriya Lyssenko, Lena Eliasson, Olga Kotova, Kasper Pilgaard, Nils Wierup, et al.
(2011) Diabetes, 60 p.2424-2433
Journal article

Polymorphisms in α- And β-adrenergic receptor genes, hypertension, and obstructive sleep apnea : The skaraborg sleep study

Kristina Bengtsson Boström, Jan Hedner, Ludger Grote, Olle Melander, Fredrik Von Wowern, et al.
(2010) International Journal of Hypertension, 2010
Journal article

Bayesian methods for meta-analysis of causal relationships estimated using genetic instrumental variables.

Stephen Burgess, Simon G Thompson, CRP CHD Genetics Collaboration, Olle Melander, Göran Berglund
(2010) Statistics in Medicine
Journal article

Orthostatic Hypotension Predicts Long-Term Incidence Of Heart Failure

Artur Fedorowski, Gunnar Engström, Bo Hedblad, Olle Melander
(2010) Journal of Hypertension, 28 p.48-48
Conference paper: abstract

One-Hour Plasma Glucose Identifies Insulin Resistance and beta-Cell Dysfunction in Individuals With Normal Glucose Tolerance Cross-sectional data from the Relationship between Insulin Sensitivity and Cardiovascular Risk (RISC) study

Melania Manco, Simona Panunzi, David P. Macfarlane, Alain Golay, Olle Melander, et al.
(2010) Diabetes Care, 33 p.2090-2097
Journal article

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

Elizabeth K. Speliotes, Cristen J. Willer, Sonja I. Berndt, Keri L. Monda, Gudmar Thorleifsson, et al.
(2010) Nature Genetics, 42 p.53-937
Journal article

Genome Wide Association Study Of Blood Pressure Extremes Identifies Variant In Umod Associated With Hypertension

S. Padmanabhan, Olle Melander, T. Johnson, A. M. Di Blasio, W. K. Lee, et al.
(2010) Journal of Hypertension, 28 p.237-237
Conference paper: abstract

Brain natriuretic peptide is related to diastolic dysfunction whereas urinary albumin excretion rate is related to left ventricular mass in asymptomatic type 2 diabetes patients

Martin Magnusson, Stefan Jovinge, Kambiz Shahgaldi, Bo Israelsson, Leif Groop, et al.
(2010) Cardiovascular Diabetology, 9
Journal article

Orthostatic hypotension predicts long-term incidence of atrial fibrillation

Artur Fedorowski, Bo Hedblad, Gunnar Engström, J. G. Smith, Olle Melander
(2010) European Heart Journal, 31 p.715-715
Conference paper: abstract

Determinants Of Arterial Stiffness In An Elderly Urban Population-Based Cohort With 17 Years' Follow-Up

Lisa Bellinetto-Ford, Gerd Östling, Katarina Nägga, Olle Melander, Peter Nilsson
(2010) Journal of Hypertension, 28 p.223-223
Conference paper: abstract

Genome-wide meta-analyses identify multiple loci associated with smoking behavior

Helena Furberg, YunJung Kim, Jennifer Dackor, Eric Boerwinkle, Nora Franceschini, et al.
(2010) Nature Genetics, 42 p.134-441
Journal article

Genetic loci influencing kidney function and chronic kidney disease

John C. Chambers, Weihua Zhang, Graham M. Lord, Pim van der Harst, Debbie A. Lawlor, et al.
(2010) Nature Genetics, 42 p.373-375
Journal article

Consequences of orthostatic blood pressure variability in middle-aged men (The Malmö Preventive Project).

Artur Fedorowski, Lars Stavenow, Bo Hedblad, Göran Berglund, Peter Nilsson, et al.
(2010) Journal of Hypertension, 28 p.551-559
Journal article

Stk39 Is A Candidate Gene For Primary Hypertension Especially In Women: Results From 2 Cohort Studies In Swedes

C. Fava, M. Montagnana, E. Danese, Marketa Sjögren, Bo Hedblad, et al.
(2010) Journal of Hypertension, 28 p.238-238
Conference paper: abstract

Orthostatic hypotension and long-term incidence of atrial fibrillation: the malmo preventive project

Artur Fedorowski, Bo Hedblad, Gunnar Engström, Gustav Smith, Olle Melander
(2010) Journal of Internal Medicine, 268 p.383-389
Journal article

The common functional polymorphism -50G>T of the CYP2J2 gene is not associated with ischemic coronary and cerebrovascular events in an urban-based sample of Swedes.

Cristiano Fava, Martina Montagnana, Peter Almgren, Bo Hedblad, Gunnar Engström, et al.
(2010) Journal of Hypertension, 28 p.294-299
Journal article

Assessment of conventional cardiovascular risk factors and multiple biomarkers for the prediction of incident heart failure and atrial fibrillation.

Gustav Smith, Christopher Newton-Cheh, Peter Almgren, Joachim Struck, Nils G Morgenthaler, et al.
(2010) Journal of the American College of Cardiology, 56 p.1713-1719
Journal article

Homozygosity for the EPHX2 K55R polymorphism increases the long-term risk of ischemic stroke in men: a study in Swedes.

Cristiano Fava, Martina Montagnana, Elisa Danese, Peter Almgren, Bo Hedblad, et al.
(2010) Pharmacogenetics & Genomics, 20 p.94-103
Journal article

Atrial fibrillation in the Malmö diet and cancer study: a study of occurrence, risk factors and diagnostic validity.

J Smith, Pyotr Platonov, Bo Hedblad, Gunnar Engström, Olle Melander
(2010) European Journal of Epidemiology, 25 p.95-102
Journal article

Lack of Association Between the Trp719Arg Polymorphism in Kinesin-Like Protein-6 and Coronary Artery Disease in 19 Case-Control Studies

Themistocles L. Assimes, Hilma Holm, Sekar Kathiresan, Muredach P. Reilly, Gudmar Thorleifsson, et al.
(2010) Journal of the American College of Cardiology, 56 p.1552-1563
Journal article

Validation of Association of Hypertension at the CYP11B1/B2 Locus in Caucasians.

S. Alvarez-Madrazo, S. Padmanabhan, E. Friel, S. M. MacKenzie, M. J. Brown, et al.
(2010) Endocrine Reviews, 31
Conference paper: abstract

Genome-Wide Association Study of Blood Pressure Extremes Identifies Variant near UMOD Associated with Hypertension

Sandosh Padmanabhan, Olle Melander, Toby Johnson, Anna Maria Di Blasio, Wai K. Lee, et al.
(2010) PLoS Genetics, 6
Journal article

A dedicated investigation unit improves management of syncopal attacks (Syncope Study of Unselected Population in Malmo--SYSTEMA I).

Artur Fedorowski, Philippe Burri, Steen Juul-Möller, Olle Melander
(2010) Europace, 12 p.1322-1328
Journal article

Biological, clinical and population relevance of 95 loci for blood lipids

Tanya M. Teslovich, Kiran Musunuru, Albert V. Smith, Andrew C. Edmondson, Ioannis M. Stylianou, et al.
(2010) Nature, 466 p.707-713
Journal article

From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus

Kiran Musunuru, Alanna Strong, Maria Frank-Kamenetsky, Noemi E. Lee, Tim Ahfeldt, et al.
(2010) Nature, 466 p.2-714
Journal article

Genome wide association study of blood pressure extremes identifies variant in uromodulin gene associated with hypertension

C. E. Hastie, S. Padmanabhan, Olle Melander, T. Johnson, A. M. Di Blasio, et al.
(2010) Journal of Human Hypertension, 24 p.687-687
Conference paper: abstract

Niemann-Pick C1 Modulates Hepatic Triglyceride Metabolism and Its Genetic Variation Contributes to Serum Triglyceride Levels

Riikka-Liisa Uronen, Per Lundmark, Marju Orho-Melander, Matti Jauhiainen, Kristina Larsson, et al.
(2010) Arteriosclerosis, Thrombosis and Vascular Biology, 30 p.230-1614
Journal article

A gene score of nine LDL and HDL regulating genes is associated with fluvastatin induced cholesterol changes in women.

Viktor Hamrefors, Marju Orho-Melander, Ronald M Krauss, Bo Hedblad, Peter Almgren, et al.
(2010) Journal of Lipid Research, 51 p.625-634
Journal article

A multilocus genetic risk score for coronary heart disease: case-control and prospective cohort analyses

Samuli Ripatti, Emmi Tikkanen, Marju Orho-Melander, Aki S. Havulinna, Kaisa Silander, et al.
(2010) The Lancet, 376 p.1393-1400
Journal article

Genetic susceptibility for obesity increases the risk of type 2 diabetes and is modified by macronutrient intakes

Gull Rukh, Emily Sonestedt, Valeriya Lyssenko, Amitabh Sharma, Olle Melander, et al.
(2010) Diabetologia, 53 p.50-50
Conference paper: abstract

Second-hand Smoke, Cotinine Levels, and Risk of Circulatory Mortality in a Large Cohort Study of Never-Smokers.

Valentina Gallo, David Neasham, Luisa Airoldi, Pietro Ferrari, Mazda Jenab, et al.
(2010) Epidemiology, 21 p.207-214
Journal article

Orthostatic Hypotension Predicts Incidence of Heart Failure: The Malmö Preventive Project.

Artur Fedorowski, Gunnar Engström, Bo Hedblad, Olle Melander
(2010) American Journal of Hypertension, 23 p.1209-1215
Journal article

Plasma copeptin and the risk of diabetes mellitus.

Sofia Enhörning, Thomas J Wang, Peter Nilsson, Peter Almgren, Bo Hedblad, et al.
(2010) Circulation, 121 p.51-2102
Journal article

Population-based study of lung function and incidence of heart failure hospitalisations.

Gunnar Engström, Olle Melander, Bo Hedblad
(2010) Thorax, 65 p.633-638
Journal article

Weak associations between human leucocyte antigen genotype and acute myocardial infarction.

Harry Björkbacka, E H Lavant, Gunilla Nordin Fredrikson, Olle Melander, Göran Berglund, et al.
(2010) Journal of Internal Medicine, 268 p.50-58
Journal article

Cardiovascular and cancer mortality in very elderly post-myocardial infarction patients receiving statin treatment.

Klas Gränsbo, Olle Melander, Lars Wallentin, Johan Lindbäck, Ulf Stenestrand, et al.
(2010) Journal of the American College of Cardiology, 55 p.1362-1369
Journal article

Orthostatic hypotension predicts all-cause mortality and coronary events in middle-aged individuals (The Malmo Preventive Project).

Artur Fedorowski, Lars Stavenow, Bo Hedblad, Göran Berglund, Peter Nilsson, et al.
(2010) European Heart Journal, 31 p.85-91
Journal article

Vanin-1 I26T Polymorphism And Hypertension In Two Large Urban-Based Prospective Studies In Swedes

C. Fava, M. Montagnana, E. Danese, Marketa Sjögren, Bo Hedblad, et al.
(2010) Journal of Hypertension, 28 p.341-341
Conference paper: abstract

Genome-wide association study identifies eight loci associated with blood pressure

Christopher Newton-Cheh, Toby Johnson, Vesela Gateva, Martin D. Tobin, Murielle Bochud, et al.
(2009) Nature Genetics, 41 p.666-676
Journal article

Orthostatic hypotension: revision of the definition is needed Reply

Artur Fedorowski, Olle Melander
(2009) Journal of Hypertension, 27 p.2120-2120
Journal article (letter)

The common functional polymorphism-50g > t of the cyp2j2 gene is not associated with coronary and cerebrovascular events in an urban based sample of Swedes

Cristiano Fava, M. Montagnana, Göran Berglund, P. Minuz, Olle Melander
(2009) Journal of Hypertension, 27 p.450-450
Conference paper: abstract

Homozygosity for the ephx2 k55r polymorphism increases the long term risk of ischemic stroke in men: a study in swedes

Cristiano Fava, M. Motagnana, Göran Berglund, P. Minuz, Olle Melander
(2009) Journal of Hypertension, 27 p.141-141
Conference paper: abstract

Biomarkers for Prediction of Cardiovascular Events Reply

Olle Melander, Christopher Newton-Cheh, Thomas J. Wang
(2009) JAMA: The Journal of the American Medical Association, 302 p.2090-2090
Journal article (letter)

Gastroparesis is associated with oxytocin deficiency, oesophageal dysmotility with hyperCCKemia, and autonomic neuropathy with hypergastrinemia

Julia Borg, Olle Melander, Linda Johansson, Kerstin Uvnas-Moberg, Jens F. Rehfeld, et al.
(2009) BMC Gastroenterology, 9
Journal article

ION Mobility Analysis Of Lipoprotein Subfractions Suggests Three Independent Mechanisms Of Cardiovascular Risk

K. Musunuru, Marju Orho-Melander, M. Caulfield, R. Reitz, Göran Berglund, et al.
(2009) Atherosclerosis Supplements, 10 p.17-17
Conference paper: abstract

Overexpression of cytochrome P450 4F2 in mice increases 20-hydroxyeicosatetraenoic acid production and arterial blood pressure

Cristiano Fava, Martina Montagnana, Olle Melander
(2009) Kidney International, 76 p.913-913
Journal article (letter)

New susceptibility locus for coronary artery disease on chromosome 3q22.3

Jeanette Erdmann, Anika Grosshennig, Peter S. Braund, Inke R. Koenig, Christian Hengstenberg, et al.
(2009) Nature Genetics, 41 p.280-282
Journal article

European GWAS strategy using extremes of blood pressure distribution

S. Padmanabhan, C. Delles, Olle Melander, C. Menni, C. Hastie, et al.
(2009) Journal of Hypertension, 27 p.166-166
Conference paper: abstract

Ion Mobility Analysis of Lipoprotein Subfractions Identifies 3 Independent Axes of Cardiovascular Risk

Kiran Musunuru, Marju Orho-Melander, Michael P. Caulfield, Shuguang Li, Wael A. Salameh, et al.
(2009) Circulation, 119 p.282-283
Conference paper: abstract

Genetic variation in serum and glucocortocoid regulated kinase 1 (SGK-1), a regulator of the epithelial sodium channel, is associated with ischemic stroke

J. Dahlberg, J. G. Smith, B. Norrvig, P. Nilsson, B. Hedblad, et al.
(2009) Journal of Hypertension, 27 p.33-33
Conference paper: abstract

Associations Between Human Leukocyte Antigen (HLA) Genotype And Acute Myocardial Infarction

Harry Björkbacka, E. Lavant, Gunilla Nordin Fredrikson, Olle Melander, Göran Berglund, et al.
(2009) Atherosclerosis Supplements, 10 p.953-953
Conference paper: abstract

Leukocyte Count and Incidence of Hospitalizations Due to Heart Failure

Gunnar Engström, Olle Melander, Bo Hedblad
(2009) Circulation Heart Failure, 2 p.217-222
Journal article

Gender differences in the association between NT proBNP and glucometabolic disturbances in a population-based cohort

Margrét Leosdottir, Ronnie Willenheimer, Christian Hall, Solve Tjora, Johan Malm, et al.
(2009) Cardiology, 113 p.48-48
Conference paper: abstract

Ion Mobility Analysis of Lipoprotein Subfractions Identifies Three Independent Axes of Cardiovascular Risk.

Kiran Musunuru, Marju Orho-Melander, Michael P Caulfield, Shuguang Li, Wael A Salameh, et al.
(2009) Arteriosclerosis, Thrombosis and Vascular Biology, 29 p.628-1975
Journal article

Distribution and Correlates of Midregional Proadrenomedullin in the General Population.

J Gustav Smith, Christopher Newton-Cheh, Bo Hedblad, Joachim Struck, Nils G Morgenthaler, et al.
(2009) Clinical Chemistry, 55 p.1593-1595
Journal article

Carotid Intima-Media Thickness, Systemic Inflammation, and Incidence of Heart Failure Hospitalizations.

Gunnar Engström, Olle Melander, Bo Hedblad
(2009) Arteriosclerosis, Thrombosis and Vascular Biology, 29 p.1691-1695
Journal article

The metabolic syndrome and risk of myocardial infarction in familial hypertension (Hypertension Heredity in Malmö Evaluation study).

Artur Fedorowski, Philippe Burri, Lennart Hulthén, Olle Melander
(2009) Journal of Hypertension, 27 p.109-117
Journal article

Chromosome 2q12, the ADRA2B I/D polymorphism and metabolic syndrome.

Cristiano Fava, Martina Montagnana, Massimo Guerriero, Peter Almgren, Fredrik von Wowern, et al.
(2009) Journal of Hypertension, 27 p.1794-1803
Journal article

The myocardial infarction associated CDKN2A/CDKN2B locus on chromosome 9p21 is associated with stroke independently of coronary events in patients with hypertension.

Björn Wahlstrand, Marju Orho-Melander, Lotta Delling, Sverre Kjeldsen, Krzysztof Narkiewicz, et al.
(2009) Journal of Hypertension, 27 p.769-773
Journal article

Novel and conventional biomarkers for prediction of incident cardiovascular events in the community.

Olle Melander, Christopher Newton-Cheh, Peter Almgren, Bo Hedblad, Göran Berglund, et al.
(2009) JAMA: The Journal of the American Medical Association, 302 p.49-57
Journal article

Orthostatic hypotension in genetically related hypertensive and normotensive individuals.

Artur Fedorowski, Philippe Burri, Olle Melander
(2009) Journal of Hypertension, 27 p.976-982
Journal article

Common Genetic Variants on Chromosome 9p21 Confers Risk of Ischemic Stroke A Large-Scale Genetic Association Study

Gustav Smith, Olle Melander, Håkan Lövkvist, Bo Hedblad, Gunnar Engström, et al.
(2009) Circulation: Cardiovascular Genetics, 2 p.159-164
Journal article

Increased pulse pressure is a marker for aortic stiffness independent of mean arterial pressure, age, sex, and other well-known cardiovascular risk factors

Lisa Bellinetto-Ford, Olle Melander, T. Lanne, Peter Nilsson
(2009) Journal of Hypertension, 27 p.23-23
Conference paper: abstract

Association of common variants in NPPA and NPPB with circulating natriuretic peptides and blood pressure

Christopher Newton-Cheh, Martin G. Larson, Ramachandran S. Vasan, Daniel Levy, Kenneth D. Bloch, et al.
(2009) Nature Genetics, 41 p.348-353
Journal article

Gene-centric Association Signals for Lipids and Apolipoproteins Identified via the HumanCVD BeadChip

Philippa J. Talmud, Fotios Drenos, Sonia Shah, Tina Shah, Jutta Palmen, et al.
(2009) American Journal of Human Genetics, 85 p.628-642
Journal article

Homozygosity for the EPHX2 K55R Polymorphism Increases the Long-Term Risk of Ischemic Stroke in Men: A Study in Swedes

Cristiano Fava, Martina Montagnana, Peter Almgren, Pietro Minuz, Olle Melander
(2009) Arteriosclerosis, Thrombosis, and Vascular Biology, 29 p.23-24
Conference paper: abstract

Fasting insulin has a stronger association with an adverse cardiometabolic risk profile than insulin resistance: the RISC study

Susanne R. de Rooij, Jacqueline M. Dekker, Nlichaela Kozakova, Asimina Mitrakou, Olle Melander, et al.
(2009) European Journal of Endocrinology, 161 p.223-230
Journal article

A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium

Nicole Soranzo, Tim D. Spector, Massimo Mangino, Brigitte Kuehnel, Augusto Rendon, et al.
(2009) Nature Genetics, 41 p.38-1182
Journal article

Common variants at 30 loci contribute to polygenic dyslipidemia

Sekar Kathiresan, Cristen J. Willer, Gina M. Peloso, Serkalem Demissie, Kiran Musunuru, et al.
(2009) Nature Genetics, 41 p.56-65
Journal article

Relation between human vasopressin 1a gene variance, fat intake, and diabetes.

Sofia Enhörning, Margrét Leosdottir, Peter Wallström, Bo Gullberg, Göran Berglund, et al.
(2009) The American journal of clinical nutrition, 89 p.400-406
Journal article

Determinants of kidney function in Swedish families. Role of heritable factors

Cristiano Fava, Martina Montagnana, Philippe Burri, Peter Almgren, Olle Melander
(2008) Journal of Hypertension, 26 p.131-131
Conference paper: abstract

Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans

Sekar Kathiresan, Olle Melander, Candace Guiducci, Aarti Surti, Noel P Burtt, et al.
(2008) Nature Genetics, 40 p.189-197
Journal article

Phenotype associated with human vasopressin receptor 1a (V1aR) gene variance is dependent on fat intake and resembles the phenotype of the V1aR knock out mouse

Sofia Enhörning, Margrét Leosdottir, Peter Wallström, Bo Gullberg, Göran Berglund, et al.
(2008) Journal of Hypertension, 26 p.144-144
Conference paper: abstract

Functional polymorphism of the NEDD4L gene strongly influences cardiovascular outcome in hypertensive patients treated with beta-blockers and diuretics

Patrik Svensson, B Wahlstrand, S Skrtic, Peter Almgren, S Kjeldsen, et al.
(2008) Journal of Hypertension, 26 p.143-144
Conference paper: abstract

The myocardial infarction associated CDKN2A/CDKN2B locus on chromosome 9p21 is associated with stroke independently of cardiovascular risk factors and coronary events in patients with hypertension

B Waldstrand, Marju Orho-Melander, S Kjeldsen, L Delling, K Narkiewicz, et al.
(2008) Journal of Hypertension, 26 p.141-142
Conference paper: abstract

Functional variation of the NEDD4L gene predicts ischemic stroke

Jonas Dahlberg, Fredrik Wowern, Peter Almgren, Göran Berglund, Bo Hedblad, et al.
(2008) Journal of Hypertension, 26 p.134-134
Conference paper: abstract

Determinants of kidney function in Swedish families: role of heritable factors.

Cristiano Fava, Martina Montagnana, Philippe Burri, Peter Almgren, Pietro Minuz, et al.
(2008) Journal of Hypertension, 26 p.1773-1779
Journal article

An association between Type 2 diabetes and alpha(1)-antitrypsin deficiency

Caroline Sandström, Bodil Ohlsson, Olle Melander, Ulla Westin, R Mahadeva, et al.
(2008) Diabetic Medicine, 25 p.1370-1373
Journal article

Association between an estrogen receptor alpha polymorphism (ERA : rs2234693) and the metabolic syndrome and cardiovascular and cerebrovascular morbidity and mortality

L Delling, B Wahlstrand, A Niklasson, K Stenlof, Marju Orho-Melander, et al.
(2008) Journal of Hypertension, 26 p.341-341
Conference paper: abstract

The Pro12Ala polymorphism of the PPARG gene is not associated with the metabolic syndrome in an urban population of middle-aged Swedish individuals.

Martina Montagnana, Cristiano Fava, Peter Nilsson, Gunnar Engström, Bo Hedblad, et al.
(2008) Diabetic Medicine: A journal of the British Diabetic Association, 25 p.902-908
Journal article

Telomere Length Is Associated With Obesity Parameters but With a Gender Difference

Katarina Nordfjall, Mats Eliasson, Birgitta Stegmayr, Olle Melander, Peter Nilsson, et al.
(2008) Obesity, 16 p.2682-2689
Journal article

Subjects heterozygous for genetic loss of function of the thiazide-sensitive cotransporter have reduced blood pressure

Cristiano Fava, Martina Montagnana, Lena Nilsson, Philippe Burri, Peter Almgren, et al.
(2008) Human Molecular Genetics, 17 p.413-418
Journal article

Interaction Between Renal Function and Microalbuminuria for Cardiovascular Risk in Hypertension The Nordic Diltiazem Study

Patrik Svensson, Bjorn Wahlstrand, Peter Almgren, Stanko Skrtic, Jan Lanke, et al.
(2008) Hypertension, 52 p.115-122
Journal article

Determinants of increasing pulse pressure during 23 years' follow-up as a marker of arterial stiffness and vascular ageing.

Arash X Mokhtari, Lisa Bellinetto-Ford, Olle Melander, Peter Nilsson
(2008) Blood Pressure, 17 p.291-297
Journal article

The V433M Variant of the CYP4F2 Is Associated With Ischemic Stroke in Male Swedes Beyond Its Effect on Blood Pressure.

Cristiano Fava, Martina Montagnana, Peter Almgren, Lena Nilsson, Giuseppe Lippi, et al.
(2008) Hypertension, 52 p.373-380
Journal article

Heritability of the ambulatory arterial stiffness index in Swedish families.

Cristiano Fava, M S Ricci, Philippe Burri, P Minuz, Olle Melander
(2008) Journal of Human Hypertension, 22 p.298-300
Journal article

Job strain, job demands and adrenergic beta1-receptor-polymorphism: a possible interaction affecting blood pressure in men.

Bertil Öhlin, Göran Berglund, Peter Nilsson, Olle Melander
(2008) Journal of Hypertension, 26 p.1583-1589
Journal article

The P2Y(13) Met-158-Thr Polymorphism, Which Is in Linkage Disequilibrium with the P2Y(12) Locus, Is Not Associated with Acute Myocardial Infarction.

Stefan Amisten, Oscar O Braun, Lovisa Johansson, Martin Ridderstråle, Olle Melander, et al.
(2008) PLoS ONE, 3
Journal article

Genetics of cardiovascular disease: interplay between common and rare alleles.

Olle Melander
(2008) Journal of Hypertension, 26 p.394-395
Journal article

Hypertension and genome-wide association studies: combining high fidelity phenotyping and hypercontrols.

Sandosh Padmanabhan, Olle Melander, Claire Hastie, Cristina Menni, Christian Delles, et al.
(2008) Journal of Hypertension, 26 p.1275-1281
Journal article

Determinants of increasing pulse pressure during 26 years' follow-up, as a marker of arterial stiffness and early vascular ageing (EVA)

Lisa Bellinetto-Ford, Arash X Mokhtari, Olle Melander, P M Nilsson
(2008) Journal of Hypertension, 26 p.117-117
Conference paper: abstract

Common Missense Variant in the Glucokinase Regulatory Protein Gene Is Associated With Increased Plasma Triglyceride and C-Reactive Protein but Lower Fasting Glucose Concentrations

Marju Orho-Melander, Olle Melander, Candace Guiducci, Pablo Perez-Martinez, Dolores Corella, et al.
(2008) Diabetes, 57 p.3112-3121
Journal article

Polymorphism associated with cholesterol and risk of cardiovascular events

Sekar Kathiresan, Olle Melander, Dragi Anevski, Candace Guiducci, Noël Burtt, et al.
(2008) New England Journal of Medicine, 358 p.1240-1249
Journal article

Increased risk of acute myocardial infarction and elevated levels of C-reactive protein in carriersof the Thr-87 variant of the ATP receptor P2Y11.

Stefan Amisten, Olle Melander, Anna-Karin Wihlborg, Göran Berglund, David Erlinge
(2007) European Heart Journal, 28 p.13-18
Journal article

Association between adducin-1 G460W variant and blood pressure in Swedes is dependent on interaction with body mass index and gender.

Cristiano Fava, Martina Montagnana, Peter Almgren, Lena Nilsson, Gian Cesare Guidi, et al.
(2007) American Journal of Hypertension, 20 p.981-989
Journal article

Novel mutations in the SLC12A3 gene causing Gitelman's syndrome in Swedes

Cristiano Fava, Martina Montagnana, Lena Nilsson, Philippe Burri, Anders Jonsson, et al.
(2007) DNA Sequence, 18 p.395-399
Journal article

Interaction between the angiotensin-converting enzyme gene insertion/deletion polymorphism and obstructive sleep apnoea as a mechanism for hypertension.

Kristina Bengtsson Boström, Jan Hedner, Olle Melander, Ludger Grote, Bo Gullberg, et al.
(2007) Journal of Hypertension, 25 p.779-783
Journal article

Oesophageal dysmotility, delayed gastric emptying and gastrointestinal symptoms in patients with diabetes mellitus.

Julia Borg, Olle Melander, Göran Sundkvist, Rolf Olsson, Ola Thorsson, et al.
(2007) Diabetic Medicine, 24 p.1235-1239
Journal article

Moderate salt restriction effectively lowers blood pressure and degree of salt sensitivity is related to baseline concentration of renin and N-terminal atrial natriuretic peptide in plasma.

Olle Melander, Fredrik Wowern, Erik Frandsen, Philippe Burri, Gunilla Willsteen, et al.
(2007) Journal of Hypertension, 25 p.619-627
Journal article

Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels

Richa Saxena, Benjamin F. Voight, Valeriya Lyssenko, Noel P. Burtt, Paul I. W. de Bakker, et al.
(2007) Science, 316 p.1331-1336
Journal article

A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study

Sekar Kathiresan, Alisa K. Manning, Serkalem Demissie, Ralph B. D'Agostino, Aarti Surti, et al.
(2007) BMC Medical Genetics, 8
Journal article

hTERT T-1327/C polymorphism is not associated with age-related telomere attrition in peripheral blood

Katarina Nordfjall, Pia Osterman, Olle Melander, Peter Nilsson, Goran Roos
(2007) Biochemical and Biophysical Research Communications, 358 p.215-218
Journal article

Are minor gene effects of clinical importance?

Olle Melander
(2007) Journal of Hypertension, 25 p.505-507
Journal article (letter)

Job strain, decision latitude and alpha2B-adrenergic receptor polymorphism significantly interact, and associate with higher blood pressures in men.

Bertil Öhlin, Göran Berglund, Peter Nilsson, Olle Melander
(2007) Journal of Hypertension, 25 p.1613-1619
Journal article

The functional variant of the CLC-Kb channel T481S is not associated with blood pressure or hypertension in Swedes.

Cristiano Fava, Martina Montagnana, Peter Almgren, Lena Nilsson, Gian Cesare Guidi, et al.
(2007) Journal of Hypertension, 25 p.111-116
Journal article

Polymorphism in NEDD4L Is Associated with Increased Salt Sensitivity, Reduced Levels of P-renin and Increased Levels of Nt-proANP.

Jonas Dahlberg, Lars-Olof Nilsson, Fredrik von Wowern, Olle Melander
(2007) PLoS ONE, 2 p.432-432
Journal article

EPIC-Heart: The cardiovascular component of a prospective study of nutritional, lifestyle and biological factors in 520,000 middle-aged participants from 10 European countries

John Danesh, Rodolfo Saracci, Göran Berglund, Edith Feskens, Kim Overvad, et al.
(2007) European Journal of Epidemiology, 22 p.129-141
Journal article

Oesophageal dysmotility, delayed gastric emptying and autonomic neuropathy correlate to disturbed glucose homeostasis.

Bodil Ohlsson, Olle Melander, Ola Thorsson, Rolf Olsson, Olle Ekberg, et al.
(2006) Diabetologia, 49 p.2010-2014
Journal article

Multilevel analysis of systolic blood pressure and ACE gene I/D polymorphism in 438 Swedish families - a public health perspective

Juan Merlo, Kristina Bengtsson Boström, Ulf Lindblad, Lennart Råstam, Olle Melander
(2006) BMC Medical Genetics, 7
Journal article

Polymorphism in the MHC2TA gene is associated with features of the metabolic syndrome and cardiovascular mortality.

Eero Lindholm, Olle Melander, Peter Almgren, Göran Berglund, Carl-David Agardh, et al.
(2006) PLoS ONE, 1
Journal article

Salt sensitivity: a consequence of the metabolic syndrome?

Olle Melander
(2006) Journal of Hypertension, 24 p.1475-1477
Journal article (letter)

24-hour Ambulatory Blood Pressure is Linked to Chromosome 18q21-22 and Genetic Variation of NEDD4L Associates with Cross-Sectional and Longitudinal Blood Pressure in Swedes.

Cristiano Fava, Fredrik Wowern, Göran Berglund, Jonas Carlson, Bo Hedblad, et al.
(2006) Kidney International, 70 p.562-569
Journal article

Dipping and variability of blood pressure and heart rate at night are heritable traits.

Cristiano Fava, Philippe Burri, Peter Almgren, Guido Arcaro, Leif Groop, et al.
(2005) American Journal of Hypertension, 18 p.1402-1407
Conference paper

Genetic variance of SGK-1 is associated with blood pressure, blood pressure change over time and strength of the insulin-diastolic blood pressure relationship.

Fredrik von Wowern, Göran Berglund, Joyce Carlson, Henrik Månsson, Bo Hedblad, et al.
(2005) Kidney International, 68 p.85-85
Journal article

Nt-proANP in plasma, a marker of salt sensitivity, is reduced in type 2 diabetes patients.

Olle Melander, E Frandsen, Martin Magnusson, Anders Grubb, Stefan Jovinge, et al.
(2005) Journal of Internal Medicine, 257 p.281-288
Journal article

Meta-analysis of genome-wide scans for hypertension and blood pressure in Caucasians shows evidence of susceptibility regions on chromosomes 2 and 3.

Liisa Koivukoski, Sheila A. Fisher, Timo Kanninen, Cathryn M. Lewis, Fredrik Wowern, et al.
(2004) Human Molecular Genetics, 13 p.2325-2332
Journal article

Elevated Plasma Levels of Nt-proBNP in Patients With Type 2 Diabetes Without Overt Cardiovascular Disease.

Martin Magnusson, Olle Melander, Bo Israelsson, Anders Grubb, Leif Groop, et al.
(2004) Diabetes Care, 27 p.1929-1935
Journal article

Heritability of ambulatory and office blood pressure phenotypes in Swedish families.

Cristiano Fava, Philippe Burri, Peter Almgren, Leif Groop, Lennart Hulthén, et al.
(2004) Journal of Hypertension, 22 p.1717-1721
Journal article

Urinary excretion rate of tamm-horsfall protein is related to salt intake in humans.

Ole Torffvit, Olle Melander, U Lennart Hultén
(2004) Nephron Physiology, 97 p.6-31
Journal article

A Functional Variant in the {alpha}2B Adrenoceptor Gene, a Positional Candidate on Chromosome 2, Associates With Hypertension.

Fredrik Wowern, Kristina Bengtsson Boström, Ulf Lindblad, Lennart Råstam, Olle Melander
(2004) Hypertension, 43 p.592-597
Journal article

Inhibition of lipolysis during acute GH exposure increases insulin sensitivity in previously untreated GH-deficient adults.

Mikael Segerlantz, Margareta Bramnert, Per Manhem, Esa Laurila, Leif Groop, et al.
(2003) European Journal of Endocrinology, 149 p.511-519
Journal article

Intrauterine growth and blood pressure: what causes the relationship?

Olle Melander
(2003) Journal of Hypertension, 21 p.1245-1247
Journal article (comment)

Peroxisome proliferator-activated receptor-gammaPro12Ala polymorphism and the association with blood pressure in type 2 diabetes: Skaraborg Hypertension and Diabetes Project.

Carl Johan Östgren, Ulf Lindblad, Olle Melander, Arne Melander, Leif Groop, et al.
(2003) Journal of Hypertension, 21 p.1657-1662
Journal article

A genome wide scan for early onset primary hypertension in Scandinavians.

Fredrik von Wowern, Kristina Bengtsson Boström, Cecilia Lindgren, Marju Orho-Melander, Frej Fyhrquist, et al.
(2003) Human Molecular Genetics, 12 p.2077-2081
Journal article

No evidence of a relation between 11beta-hydroxysteroid dehydrogenasetype 2 activity and salt sensitivity.

Olle Melander, Erik Frandsen, Leif Groop, Lennart Hulthén
(2003) American Journal of Hypertension, 16 p.729-733
Journal article

Pro-opiomelanocortin gene is associated with serum leptin levels in lean but not in obese individuals.

E Suviolahti, Martin Ridderstråle, Peter Almgren, Mia Klannemark, Olle Melander, et al.
(2003) International Journal of Obesity, 27 p.1204-1211
Journal article

Contribution of known and unknown susceptibility genes to early-onset diabetes in scandinavia: evidence for heterogeneity.

Cecilia Lindgren, Elisabeth Widén, Tiinamaija Tuomi, Haiyan Li, Peter Almgren, et al.
(2002) Diabetes, 51 p.1609-1617
Journal article

From linkage to genes in human hypertension

Olle Melander
(2002) Journal of Hypertension, 20 p.2135-2138
Journal article (comment)

Plasma ProANP(1-30) reflects salt sensitivity in subjects with heredity for hypertension

Olle Melander, E Frandsen, Leif Groop, Lennart Hulthén
(2002) Hypertension, 39 p.996-999
Journal article

The ACE gene I/D polymorphism is associated with higher mortality in men with hypertension and type 2 diabetes

K Bengtsson, Ulf Lindblad, Marju Orho-Melander, Olle Melander, Jonas Ranstam, et al.
(2001) Diabetologia, 44 p.35-35
Journal article

Beta(2)-adrenergic receptor gene variation and hypertension in subjects with type 2 diabetes

Kristina Bengtsson, Marju Orho-Melander, Olle Melander, Ulf Lindblad, Jonas Ranstam, et al.
(2001) Hypertension, 37 p.1303-1308
Journal article

Polymorphism in the beta(1)-adrenergic receptor gene and hypertension

Kristina Bengtsson, Olle Melander, Marju Orho-Melander, Ulf Lindblad, Jonas Ranstam, et al.
(2001) Circulation, 104 p.187-190
Journal article

Genetic variants of thiazide-sensitive NaCl-cotransporter in Gitelman's syndrome and primary hypertension

Olle Melander, Marju Orho-Melander, Kristina Bengtsson Boström, Ulf Lindblad, Lennart Råstam, et al.
(2000) Hypertension, 36 p.389-394
Journal article

Angiotensin converting enzyme (ACE) gene polymorphism in sarcoidosis in relation to associated autoimmune diseases

K I Papadopoulos, Olle Melander, Marju Orho-Melander, Leif Groop, M Carlsson, et al.
(2000) Journal of Internal Medicine, 247 p.71-77
Journal article

Genetic factors in primary hypertension- with emphasis on renal sodium reabsorption

Olle Melander
(2000)
Dissertation

Role of the Gly460Trp polymorphism of the alpha-adducin gene in primary hypertension in Scandinavians

Olle Melander, K Bengtsson, Marju Orho-Melander, U Lindblad, C Forsblom, et al.
(2000) Journal of Human Hypertension, 14 p.43-46
Journal article

Association between a variant in the 11 beta-hydroxysteroid dehydrogenase type 2 gene and primary hypertension

Olle Melander, Marju Orho-Melander, K Bengtsson, U Lindblad, Lennart Råstam, et al.
(2000) Journal of Human Hypertension, 14 p.819-823
Journal article

Polymorphism in the angiotensin converting enzyme but not in the angiotensinogen gene is associated with hypertension and type 2 diabetes: the Skaraborg Hypertension and diabetes project

Kristina Bengtsson Boström, Marju Orho-Melander, Ulf Lindblad, Olle Melander, Erik Bøg-Hansen, et al.
(1999) Journal of Hypertension, 17 p.1569-1575
Journal article