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Nils Wierup

Nils Wierup

Senior lecturer

Nils Wierup

Mucosal glucagon-like peptide-1 and gastric inhibitory polypeptide cell numbers in the super-obese human foregut after gastric bypass.

Author

  • Bent J Nergård
  • Andreas Lindqvist
  • Hjörtur G Gislason
  • Leif Groop
  • Mikael Ekelund
  • Nils Wierup
  • Jan Hedenbro

Summary, in English

Super-obesity, a body mass index>50 kg/m(2), is difficult to treat. Many studies have focused on the anatomic changes of the intestines; the physiologic background is not clearly identified. It is established that Roux-en-Y gastric bypass (RYGB) augments secretion of glucagon-like peptide-1 (GLP-1), peptide tyrosine tyrosine (PYY), and insulin, but other aspects of gut hormone cell function in the alimentary limb are unknown.

Department/s

  • Neuroendocrine Cell Biology
  • Genomics, Diabetes and Endocrinology
  • Surgery (Lund)
  • EXODIAB: Excellence of Diabetes Research in Sweden

Publishing year

2015

Language

English

Pages

1237-1246

Publication/Series

Surgery for Obesity and Related Diseases

Volume

11

Issue

6

Document type

Journal article

Publisher

Elsevier

Topic

  • Surgery

Status

Published

Research group

  • Neuroendocrine Cell Biology
  • Genomics, Diabetes and Endocrinology

ISBN/ISSN/Other

  • ISSN: 1550-7289