
Naeimeh Atabaki Pasdar
Doctoral student

Key interests
- Causal inference in epidemiology
- Machine learning
- Biostatistics
- Bioinformatics
- Gene x lifestyle interactions in relation to non-alcoholic fatty liver disease and type two diabetes
Background/biography
Naeimeh obtained a Bachelor's degree in biomedical engineering from Amirkabir University of Technology, Tehran, Iran. Although there has been much that she gained during her bachelor studies, it has truly been during her master studies in the bioinformatics program at Lund University that she has finally found her path within the widely multidisciplinary ‘bio’ field. To get the most out of her master studies, she started a one year master project at GAME unit, the goal of which was statistical analysis of genotype-based recall randomized controlled trials. Upon completion, Naeimeh graduated from her master studies and started her PhD studies under Paul Frank’s supervision in August 2015. In her PhD studies, Naeimeh’s main research focus is on genetic and lifestyle factors in liver fat and insulin resistance. She primarily works on data from the IMI-DIRECT consortium, diabetes research on patient stratification. T2D and NAFLD are two pervasive and globally prevalent diseases that cause serious health complications. However, it is yet undetermined whether T2D and NAFLD are causally related, and if so, what the direction and magnitude of such a causal relation is. Thus, her aim is to deduce the causal relationship between these diseases, and also, to find the omic and non-omic determinants of these diseases.
Publications
Displaying of publications. Sorted by year, then title.
A phenome-wide comparative analysis of genetic discordance between obesity and type 2 diabetes
Daniel E Coral, Juan Fernandez-Tajes, Neli Tsereteli, Hugo Pomares-Millan, Hugo Fitipaldi, et al.
(2023) Nature Metabolism
Journal articleInvestigating the causal relationships between excess adiposity and cardiometabolic health in men and women
Pascal M Mutie, Hugo Pomares-Milan, Naeimeh Atabaki-Pasdar, Daniel Coral, Hugo Fitipaldi, et al.
(2023) Diabetologia, 66 p.321-335
Journal articleEstimating the Direct Effect between Dietary Macronutrients and Cardiometabolic Disease, Accounting for Mediation by Adiposity and Physical Activity
Hugo Pomares-Millan, Naeimeh Atabaki-Pasdar, Daniel Coral, Ingegerd Johansson, Giuseppe N. Giordano, et al.
(2022) Nutrients, 14
Journal articlePredicting Sensitivity to Adverse Lifestyle Risk Factors for Cardiometabolic Morbidity and Mortality
Hugo Pomares-Millan, Alaitz Poveda, Naeimeh Atabaki Pasdar, Jonas Björk, Mattias Ohlsson, et al.
(2022) Nutrients, 14 p.1-13
Journal articleGlucose-Dependent Insulinotropic Peptide in the High-Normal Range Is Associated With Increased Carotid Intima-Media Thickness
Amra Jujić, Peter M Nilsson, Naeimeh Atabaki-Pasdar, Anna Dieden, Tiinamaija Tuomi, et al.
(2021) Diabetes Care, 44 p.224-230
Journal articleInferring causal pathways between metabolic processes and liver fat accumulation: an IMI DIRECT study
Naeimeh Atabaki-Pasdar, Hugo Pomares-Millan, Robert W Koivula, Andrea Tura, Andrew Brown, et al.
(2021) medRxiv
PreprintPredicting sensitivity and resilience to modifiable risk factors for cardiometabolic morbidity and mortality
Hugo Pomares-Millan, Naemieh Atabaki Pasdar, Ingegerd Johansson, Alaitz Poveda, Paul W. Franks
(2021) , p.1-28
PreprintMetabolic resilience is encoded in genome plasticity
Leandro Z. Agudelo, Remy Tuyeres, Claudia Llinares, Alvaro Morcuende, Yongjin Park, et al.
(2021)
PreprintAn investigation of causal relationships between prediabetes and vascular complications
Pascal M. Mutie, Hugo Pomares-Millan, Naeimeh Atabaki-Pasdar, Nina Jordan, Rachel Adams, et al.
(2020) Nature Communications, 11
Journal articleGlucose-dependent insulinotropic peptide and risk of cardiovascular events and mortality : a prospective study
Amra Jujić, Naeimeh Atabaki-Pasdar, Peter M Nilsson, Peter Almgren, Liisa Hakaste, et al.
(2020) Diabetologia, 63 p.1043-1054
Journal articleThe role of physical activity in metabolic homeostasis before and after the onset of type 2 diabetes : an IMI DIRECT study
Robert W. Koivula, Naeimeh Atabaki-Pasdar, Giuseppe N. Giordano, Tom White, Jerzy Adamski, et al.
(2020) Diabetologia, 63 p.744-756
Journal articleEnhancing prediction and causal inference in metabolic dyshomeostasis
Naeimeh Atabaki Pasdar
(2020) Lund University, Faculty of Medicine Doctoral Dissertation Series
DissertationAssociation of Established Blood Pressure Loci With 10-Year Change in Blood Pressure and Their Ability to Predict Incident Hypertension
Alaitz Poveda, Naeimeh Atabaki-Pasdar, Shafqat Ahmad, Göran Hallmans, Frida Renström, et al.
(2020) Journal of the American Heart Association, 9 p.014513-014513
Journal articlePredicting and elucidating the etiology of fatty liver disease: A machine learning modeling and validation study in the IMI DIRECT cohorts
Naeimeh Atabaki Pasdar, Mattias Ohlsson, Hugo Pomares-Millan, Robert Koivula, Azra Kurbasic, et al.
(2020) PLoS Medicine, 17 p.1003149-1003149
Journal articleGenetic studies of abdominal MRI data identify genes regulating hepcidin as major determinants of liver iron concentration
Henry R. Wilman, Naeimeh Atabaki Pasdar, Paul Franks, Giuseppe Giordano, Hugo Pomares-Millan, et al.
(2019) Journal of Hepatology, 71 p.594-602
Journal articleGenome-wide and abdominal MRI data provide evidence that a genetically determined favorable adiposity phenotype is characterized by lower ectopic liver fat and lower risk of type 2 diabetes, heart disease, and hypertension
Yingjie Ji, Andrianos M. Yiorkas, Francesca Frau, Dennis Mook-Kanamori, Harald Staiger, et al.
(2019) Diabetes, 68 p.207-219
Journal articleCausal inference in obesity research
P. W. Franks, N. Atabaki-Pasdar
(2017) Journal of Internal Medicine, 281 p.222-232
Journal article reviewStatistical power considerations in genotype-based recall randomized controlled trials
Naeimeh Atabaki-Pasdar, Mattias Ohlsson, Dmitry Shungin, Azra Kurbasic, Erik Ingelsson, et al.
(2016) Scientific Reports, 6
Journal article