Mototsugu Nagao
Affiliated researcher
Publications
Displaying of publications. Sorted by year, then title.
Fasting plasma glucose level-based formula for estimating starting daily dose in basal-bolus insulin therapy
Mototsugu Nagao, Taro Harada, Kyoko Tanimura-Inagaki, Shunsuke Kobayashi, Izumi Fukuda, et al.
(2023) Scientific Reports, 13 p.1-7
Journal articleEfficacy and safety of sitagliptin treatment in older adults with moderately controlled type 2 diabetes : the STREAM study
Mototsugu Nagao, Jun Sasaki, Hitoshi Sugihara, Kyoko Tanimura-Inagaki, Taro Harada, et al.
(2023) Scientific Reports, 13 p.1-11
Journal articleSelectively bred rodent models for studying the etiology of type 2 diabetes : Goto-Kakizaki rats and Oikawa-Nagao mice
Mototsugu Nagao, Akira Asai, Lena Eliasson, Shinichi Oikawa
(2023) Endocrine Journal, 70 p.19-30
Journal article reviewHLA analysis of immune checkpoint inhibitor-induced and idiopathic isolated ACTH deficiency
Mayo Ono, Izumi Fukuda, Mototsugu Nagao, Keiko Tomiyama, Mikiko Okazaki-Hada, et al.
(2022) Pituitary, 25 p.615-621
Journal articleThe structure of insulin granule core determines secretory capacity being reduced in type-2 diabetes
Mohammad Barghouth, Xiaoping Jiang, Mototsugu Nagao, Ning Chen, Daowei Yang, et al.
(2022)
PreprintSecretory granule exocytosis and its amplification by cAMP in pancreatic β-cells
Mototsugu Nagao, Jens O. Lagerstedt, Lena Eliasson
(2022) Diabetology International, 13 p.471-479
Journal article reviewHuman Islet MicroRNA-200c Is Elevated in Type 2 Diabetes and Targets the Transcription Factor ETV5 to Reduce Insulin Secretion
Jones Ofori, Alexandros Karagiannopoulos, Mototsugu Nagao, Efraim Westholm, Shaima Ramadan, et al.
(2022) Diabetes, 71 p.275-284
Journal articleThe highly expressed calcium-insensitive synaptotagmin-11 and synaptotagmin-13 modulate insulin secretion
Jones K Ofori, Alexandros Karagiannopoulos, Mohammad Barghouth, Mototsugu Nagao, Markus E Andersson, et al.
(2022) Acta Physiologica, 236
Journal articlePerioperative glycemic status is linked to postoperative complications in non-intensive care unit patients with type-2 diabetes : a retrospective study
Takeshi Oba, Mototsugu Nagao, Shunsuke Kobayashi, Yuji Yamaguchi, Tomoko Nagamine, et al.
(2022) Therapeutic Advances in Endocrinology and Metabolism, 13 p.1-14
Journal articleDiagnostic potential of miR-483 family for IGF-II producing non-islet cell tumor hypoglycemia
Mototsugu Nagao, Izumi Fukuda, Akira Asai, Jonathan L.S. Esguerra, Naomi Hizuka, et al.
(2021) European Journal of Endocrinology, 184 p.41-49
Journal articleMultiple daily insulin injections ameliorate QT interval by lowering blood glucose levels in patients with type 2 diabetes
Shunsuke Kobayashi, Mototsugu Nagao, Izumi Fukuda, Shinichi Oikawa, Hitoshi Sugihara
(2021) Therapeutic Advances in Endocrinology and Metabolism, 12 p.1-7
Journal articlePrenatal Nicotine Exposure Induces Low Birthweight and Hyperinsulinemia in Male Rats
Takahiro Nemoto, Hisae Ando, Mototsugu Nagao, Yoshihiko Kakinuma, Hitoshi Sugihara
(2021) Frontiers in Endocrinology, 12 p.1-11
Journal articleDifferent pathogenesis of glucose intolerance in two subtypes of primary aldosteronism : Aldosterone-producing adenoma and idiopathic hyperaldosteronism
Mikiko Okazaki-Hada, Ayako Moriya, Mototsugu Nagao, Shinichi Oikawa, Izumi Fukuda, et al.
(2020) Journal of Diabetes Investigation, 11 p.1511-1519
Journal articleInsulin and heparin challenge tests are useful for choosing an optimal insulin regimen in a case of subcutaneous insulin resistance
Yuko Nakamura, Mototsugu Nagao, Shunsuke Kobayashi, Takeshi Oba, Yuki Shuto, et al.
(2020) Journal of Diabetes Investigation, 11 p.1370-1373
Journal articleLeptin production capacity determines food intake and susceptibility to obesity-induced diabetes in Oikawa-Nagao Diabetes-Prone and Diabetes-Resistant mice
Akira Asai, Mototsugu Nagao, Koji Hayakawa, Teruo Miyazawa, Hitoshi Sugihara, et al.
(2020) Diabetologia, 63 p.1836-1846
Journal articlePotential Protection Against Type 2 Diabetes in Obesity Through Lower CD36 Expression and Improved Exocytosis in β-Cells
Mototsugu Nagao, Jonathan L S Esguerra, Akira Asai, Jones K Ofori, Anna Edlund, et al.
(2020) Diabetes, 69 p.1193-1205
Journal articleSitagliptin improves plasma apolipoprotein profile in type 2 diabetes : A randomized clinical trial of sitagliptin effect on lipid and glucose metabolism (SLIM) study
Kyoko Tanimura-Inagaki, Mototsugu Nagao, Taro Harada, Hitoshi Sugihara, Shigeki Moritani, et al.
(2020) Diabetes Research and Clinical Practice, 162 p.1-9
Journal articleSelectively Bred Diabetes Models : GK Rats, NSY Mice, and ON Mice
Mototsugu Nagao, Jonathan Lou S Esguerra, Anna Wendt, Akira Asai, Hitoshi Sugihara, et al.
(2020) Methods in molecular biology (Clifton, N.J.), 2128 p.25-54
Book chapterApolipoprotein A-I primes beta cells to increase glucose stimulated insulin secretion
Oktawia Nilsson, Rita Del Giudice, Mototsugu Nagao, Caitriona Grönberg, Lena Eliasson, et al.
(2020) Biochimica et Biophysica Acta - Molecular Basis of Disease, 1866
Journal articleGlucocorticoid induces human beta cell dysfunction by involving riborepressor GAS5 LincRNA
Jonathan L.S. Esguerra, Jones K. Ofori, Mototsugu Nagao, Yuki Shuto, Alexandros Karagiannopoulos, et al.
(2020) Molecular Metabolism, 32 p.160-167
Journal articleExposure to maternal obesity programs sex differences in pancreatic islets of the offspring in mice
Lisa M Nicholas, Mototsugu Nagao, Laura C Kusinski, Denise S Fernandez-Twinn, Lena Eliasson, et al.
(2020) Diabetologia, 63 p.324-337
Journal articleMetformin Attenuates Early-Stage Atherosclerosis in Mildly Hyperglycemic Oikawa-Nagao Mice
Akira Asai, Yuki Shuto, Mototsugu Nagao, Momoyo Kawahara, Teruo Miyazawa, et al.
(2019) Journal of Atherosclerosis and Thrombosis, 26 p.1075-1083
Journal articleMicroRNAs in islet hormone secretion
Jonathan L.S. Esguerra, Mototsugu Nagao, Jones K. Ofori, Anna Wendt, Lena Eliasson
(2018) Diabetes, Obesity and Metabolism, 20 p.11-19
Journal article reviewSeverity and multiplicity of microvascular complications are associated with QT interval prolongation in patients with type 2 diabetes
Shunsuke Kobayashi, Mototsugu Nagao, Akira Asai, Izumi Fukuda, Shinichi Oikawa, et al.
(2018) Journal of Diabetes Investigation, 9 p.946-951
Journal articleGlucotoxicity-induced upregulation of lincRNA GAS5 in the pancreatic islets of type 2 diabetes donors and in Goto-Kakizaki rats
J. L. S. Esguerra, J. Ofori, M. Nagao, J. Fadista, L. Groop, et al.
(2017) Diabetologia, 60 p.22-23
Conference paper: abstractReduced insulin secretion in a diet-induced glucose intolerance susceptible mouse model is coupled with increased CD36 and triglycerides in the beta cells
A. Asai, M. Nagao, T. Tsuduki, T. Miyazawa, J. L. S. Esguerra, et al.
(2017) , p.61-61
Conference paper: abstractCD36 is increased in human islets from obese type 2 diabetes donors, and affects beta cell function by the modulation of exocytotic proteins and insulin content
M. Nagao, J. L. S. Esguerra, J. K. Ofori, A. Wendt, A. Asai, et al.
(2017) Diabetologia, 60 p.185-186
Conference paper: abstractElevated miR-130a/miR130b/miR-152 expression reduces intracellular ATP levels in the pancreatic beta cell
Jones K. Ofori, Vishal A. Salunkhe, Annika Bagge, Neelanjan Vishnu, Mototsugu Nagao, et al.
(2017) Scientific Reports, 7
Journal articleFrequency of Achilles Tendon Xanthoma in Patients with Acute Coronary Syndrome
Taro Harada, Kyoko Tanimura-Inagaki, Mototsugu Nagao, Yuki Sato, Mariko Sudo, et al.
(2017) Journal of Atherosclerosis and Thrombosis, 24 p.949-953
Journal articlePostprandial increase in energy expenditure correlates with body weight reduction in patients with type 2 diabetes receiving diet therapy
Daisuke Sanoyama, Mototsugu Nagao, Akira Asai, Yuko Nakamura, Kazumi Sato, et al.
(2017) Journal of Atherosclerosis and Thrombosis, 24 p.422-429
Journal articleACTH stimulation test and computed tomography are useful for differentiating the subtype of primary aldosteronism
Ayako Moriya, Masaaki Yamamoto, Shunsuke Kobayashi, Tomoko Nagamine, Naomi Takeichi-Hattori, et al.
(2017) Endocrine Journal, 64 p.65-73
Journal articleAssociation of psoriasis with Hashimoto's thyroiditis, Sjögren's syndrome and dermatomyositis
Michiko Akiyama, Takashi Ueno, Akiko Kanzaki, Masataka Kuwana, Mototsugu Nagao, et al.
(2016) Journal of Dermatology, 43 p.711-712
Journal article (letter)Investigation of 3 cases of mitochondrial diabetes mellitus with mitochondrial DNA 3243 (A-G) mutation
Daisuke Sanoyama, Yuji Yamaguchi, Mototsugu Nagao, Akane Nogami, Naomi Takeichi-Hattori, et al.
(2016) Journal of the Japan Diabetes Society, 59 p.421-428
Journal articleSevere insulin-resistant diabetes due to insulin antibodies associated with eosinophilia
Makiyo Takaya, Mototsugu Nagao, Shuji Takemitsu, Yasushi Nakajima, Hitoshi Sugihara, et al.
(2015) Internal Medicine, 54 p.2367-2371
Journal articleRepetitive glucose spikes accelerate atherosclerotic lesion formation in C57BL/6 mice
Yuki Shuto, Akira Asai, Mototsugu Nagao, Hitoshi Sugihara, Shinichi Oikawa
(2015) PLoS ONE, 10 p.1-10
Journal articleFat intake and the development of type 2 diabetes
Mototsugu Nagao, Akira Asai, Hitoshi Sugihara, Shinichi Oikawa
(2015) Endocrine Journal, 62 p.561-572
Journal article reviewLiquid chromatography-tandem mass spectrometry determination of human plasma 1-palmitoyl-2-hydroperoxyoctadecadienoyl-phosphatidylcholine isomers via promotion of sodium adduct formation
Shunji Kato, Kiyotaka Nakagawa, Yuuri Suzuki, Akira Asai, Mototsugu Nagao, et al.
(2015) Analytical Biochemistry, 471 p.51-60
Journal articleTransgenerational changes of metabolic phenotypes in two selectively bred mouse colonies for different susceptibilities to diet-induced glucose intolerance
Mototsugu Nagao, Akira Asai, Hitoshi Sugihara, Shinichi Oikawa
(2015) Endocrine Journal, 62 p.371-378
Journal article (comment)Characterization of pancreatic islets in two selectively bred mouse lines with different susceptibilities to high-fat diet-induced glucose intolerance
Mototsugu Nagao, Akira Asai, Wataru Inaba, Momoyo Kawahara, Yuki Shuto, et al.
(2014) PLoS ONE, 9 p.1-7
Journal articleComparison of three α-glucosidase inhibitors for glycemic control and bodyweight reduction in Japanese patients with obese type 2 diabetes
Hitoshi Sugihara, Mototsugu Nagao, Taro Harada, Yasushi Nakajima, Kyoko Tanimura-Inagaki, et al.
(2014) Journal of Diabetes Investigation, 5 p.206-212
Journal articleEffect of impaired glucose tolerance on atherosclerotic lesion formation : An evaluation in selectively bred mice with different susceptibilities to glucose intolerance
Akira Asai, Mototsugu Nagao, Momoyo Kawahara, Yuki Shuto, Hitoshi Sugihara, et al.
(2013) Atherosclerosis, 231 p.421-426
Journal articleAssociation of glycated albumin with the presence of carotid plaque in patients with type 2 diabetes
Yuki Sato, Mototsugu Nagao, Akira Asai, Yasushi Nakajima, Makiyo Takaya, et al.
(2013) Journal of Diabetes Investigation, 4 p.634-639
Journal articleFoxO1 breaks diabetic heart
Mototsugu Nagao, Akira Asai, Shinichi Oikawa
(2013) Journal of Diabetes Investigation, 4 p.37-38
Journal article (comment)Evaluation of glycemic variation with continuous glucose monitoring in unstable diabetes caused by anti-insulin antibodies
Mototsugu Nagao, Yasushi Nakajima, Yuki Sato, Makiyo Takaya, Naomi Takeichi-Hattori, et al.
(2012) Journal of the Japan Diabetes Society, 55 p.874-879
Journal articleSelective breeding of mice for different susceptibilities to high fat diet-induced glucose intolerance : Development of two novel mouse lines, Selectively bred Diet-induced Glucose intolerance-Prone and -Resistant
Mototsugu Nagao, Akira Asai, Momoyo Kawahara, Yasushi Nakajima, Yuki Sato, et al.
(2012) Journal of Diabetes Investigation, 3 p.245-251
Journal articleInvolvement of Rac GTPase activation in phosphatidylcholine hydroperoxide-induced THP-1 cell adhesion to ICAM-1
Akira Asai, Fumitaka Okajima, Yasushi Nakajima, Mototsugu Nagao, Kiyotaka Nakagawa, et al.
(2011) Biochemical and Biophysical Research Communications, 406 p.273-277
Journal articlePractical dietary calorie management, body weight control and energy expenditure of diabetic patients in short-term hospitalization
Yasushi Nakajima, Kazumi Sato, Mariko Sudo, Mototsugu Nagao, Toshiko Kano-Wakakuri, et al.
(2010) Journal of Atherosclerosis and Thrombosis, 17 p.558-567
Journal articleComparison of pituitary-adrenal responsiveness between insulin tolerance test and growth hormone-releasing peptide-2 test : A pilot study
Toshiko Kano-Wakakuri, Hitoshi Sugihara, Mariko Sudo, Mototsugu Nagao, Taro Harada, et al.
(2010) Peptides, 31 p.657-661
Journal articlePhosphatidylcholine hydroperoxide-induced THP-1 cell adhesion to intracellular adhesion molecule-1
Akira Asai, Fumitaka Okajima, Kiyotaka Nakagawa, Daigo Ibusuki, Kyoko Tanimura-Inagaki, et al.
(2009) Journal of Lipid Research, 50 p.65-957
Journal articleAssociation of serum apolipoprotein B48 level with the presence of carotid plaque in type 2 diabetes mellitus
Kyoko Tanimura-Inagaki, Yasushi Nakajima, Mototugu Nagao, Akira Ishizaki, Toshiko Kano-Wakakuri, et al.
(2008) Diabetes Research and Clinical Practice, 81 p.338-344
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