Mohammad Tariq

Current project

Mohammad Tariz is studying the function of insulin-secreting pancreatic beta-cells in physiological, inflammatory and pathophysiological conditions. Our aim is to understand the moleculr mechanisms of pancreatic interventions. His focus will be to understand the role of mitochondrial voltage-dependent anion channel (VDAC1) primarily in pancreatic beta-cell dysfunction and explore the molecular mechanisms of VDAC1-induced beta-cell apoptosis.

Background

Mohammad Tariq has obtained his PhD in life sciences from RIKEN and Saitama University, Japan. The main focus of his PhD thesis was to study the regulation of post-translational modifications of an important translation factor elF5A- After his PhD Mohammad joined Université atholique de Louvain, Bergium as a Postdock Fellow to study the glucotoxic alterations of pancreatic beta cell function.

Mohammad has experience of working with mouse and human islets, measurements of NADPH autofluorescence and intracellular calcium of pancreatic islets by microspectrofluorimetry, standard molecular biology techniques, Glucose-stimulated insulin secretion, Immunohistochemistry, western blotting, adenoviral vector construction, RNAi-mediated gene seilencing.