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Photo: KG Pressfoto

Marju Orho-Melander

Professor

Photo: KG Pressfoto

Interaction between rs10830963 polymorphism in MTNR1B and lifestyle intervention on occurrence of gestational diabetes

Author

  • Nora E. Grotenfelt
  • Niko S. Wasenius
  • Kristiina Rönö
  • Hannele Laivuori
  • Beata Stach-Lempinen
  • Marju Orho-Melander
  • Christina Alexandra Schulz
  • Hannu Kautiainen
  • Saila B. Koivusalo
  • Johan G. Eriksson

Summary, in English

Aims/hypothesis: The aim of this study was to assess the interaction between melatonin receptor 1B gene (MTNR1B) rs10830963 polymorphism and lifestyle intervention during pregnancy on occurrence of gestational diabetes mellitus (GDM) in high-risk women. Methods: This is a secondary analysis of the randomised controlled gestational diabetes prevention trial ‘RADIEL’, conducted between 2008 and 2014 in four maternity hospitals in southern Finland. A total of 226 women with a history of GDM and/or a pre-pregnancy BMI ≥ 30 kg/m2 were enrolled at

Department/s

  • Department of Clinical Sciences, Malmö
  • EXODIAB: Excellence of Diabetes Research in Sweden
  • EpiHealth: Epidemiology for Health

Publishing year

2016-08

Language

English

Pages

1655-1658

Publication/Series

Diabetologia

Volume

59

Issue

8

Document type

Journal article

Publisher

Springer

Topic

  • Endocrinology and Diabetes

Keywords

  • Clinical trial
  • Diabetes
  • Gestational
  • Melatonin
  • MT2
  • Polymorphism
  • Pregnancy
  • Prevalence
  • Public health
  • Receptor
  • Single nucleotide

Status

Published

ISBN/ISSN/Other

  • ISSN: 0012-186X