"VDAC1 a common denominator of ß-cell and endothelial cell dysfunction in T2D with its complications". This project aims to identify and map the importance of mitochondrial voltage dependent-anion channel (VDAC) proteins in beta, kidney and endothelial cells under physiological and pathophysiological conditions.
Techniques such as in vitro studies and cell culture, transfection, pharmacological approached, qPCR, Western Blot, ELISA and confocal immunofluorescence microscopy will be used during the project.
I have a PhD degree in biomedical science with specialization in neuroendocrine pharmacology from the Brain Disease Biomarker Unit at BMC, Lund University in Sweden. We were targeting emergy metabolism with genetic and pharmacological approaches using in vivo and in vitro studies, trying to find new treatments in Huntingtons´s disease. Different techniques such as qPCR, Western Blot, ELISA, bright field microscopy; primary satellite cell culture, whole body perfusion, dissection, and blood sampling were used. I have experience in generating a novel mouse model, as well as performing behavior tests (paw clasping, open field, rotarod, marble burying, and novel object recognition) in mice. I have had the chance to publish my research as well as attend to different international conferences and seminars.
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