Maria Gomez

Perspectives on a Way Forward to Implementation of Precision Medicine in Patients With Diabetic Kidney Disease; Results of a Stakeholder Consensus-Building Meeting

Elisabeth Bakker, Peter G.M. Mol, João Nabais, Thorsten Vetter, Matthias Kretzler, et al.
(2021) Frontiers in Pharmacology, 12
Journal article

Attributes and predictors of long COVID

Carole H. Sudre, Benjamin Murray, Thomas Varsavsky, Mark S. Graham, Rose S. Penfold, et al.
(2021) Nature Medicine, 27 p.626-631
Journal article

Glucose-Dependent Insulinotropic Peptide in the High-Normal Range Is Associated With Increased Carotid Intima-Media Thickness

Amra Jujić, Peter M Nilsson, Naeimeh Atabaki-Pasdar, Anna Dieden, Tiinamaija Tuomi, et al.
(2021) Diabetes Care, 44 p.224-230
Journal article

Cancer and Risk of COVID-19 Through a General Community Survey

Karla A. Lee, Wenjie Ma, Daniel R. Sikavi, David A. Drew, Long H. Nguyen, et al.
(2021) The Oncologist, 26
Journal article

Symptoms and syndromes associated with SARS-CoV-2 infection and severity in pregnant women from two community cohorts

Erika Molteni, Christina M. Astley, Wenjie Ma, Carole H. Sudre, Laura A. Magee, et al.
(2021) Scientific Reports, 11
Journal article

Symptom clusters in COVID-19 : A potential clinical prediction tool from the COVID Symptom Study app

Carole H. Sudre, Karla A. Lee, Mary Ni Lochlainn, Thomas Varsavsky, Benjamin Murray, et al.
(2021) Science Advances, 7
Journal article

Detecting COVID-19 infection hotspots in England using large-scale self-reported data from a mobile application : a prospective, observational study

Thomas Varsavsky, Mark S. Graham, Liane S. Canas, Sajaysurya Ganesh, Joan Capdevila Pujol, et al.
(2021) The Lancet Public Health, 6 p.21-29
Journal article

Technological readiness and implementation of genomic-driven precision medicine for complex diseases

P. W. Franks, E. Melén, M. Friedman, J. Sundström, I. Kockum, et al.
(2021) Journal of Internal Medicine, 290 p.602-620
Journal article review

Kv1.3 Channel, a Targetable Piece in the Complex Jigsaw Puzzle of Vascular Calcification?

Maria F Gomez
(2020) Function, 2 p.1-3
Journal article (comment)

SARS-CoV-2 (COVID-19) infection in pregnant women : characterization of symptoms and syndromes predictive of disease and severity through real-time, remote participatory epidemiology

Erika Molteni, Christina M Astley, Wenjie Ma, Carole Helene Sudre, Laura A Magee, et al.
(2020) MedRxiv
Other

Glucose-dependent insulinotropic peptide and risk of cardiovascular events and mortality : a prospective study

Amra Jujić, Naeimeh Atabaki-Pasdar, Peter M Nilsson, Peter Almgren, Liisa Hakaste, et al.
(2020) Diabetologia, 63 p.1043-1054
Journal article

Syndecan-4 Protects the Heart From the Profibrotic Effects of Thrombin-Cleaved Osteopontin

Kate M. Herum, Andreas Romaine, Ariel Wang, Arne Olav Melleby, Mari E. Strand, et al.
(2020) Journal of the American Heart Association, 9 p.013518-013518
Journal article

Prognostic imaging biomarkers for diabetic kidney disease (iBEAt): study protocol

Kim Gooding, Marlena Maziarz, Anna-Maria Dutius Andersson, Anna Zetterqvist, Maria F Gomez, et al.
(2020) BMC Nephrology, 21
Journal article

Inhibition of NFAT signaling restores microvascular endothelial function in diabetic mice

Eliana Garcia-Vaz, Alison D. McNeilly, Lisa M. Berglund, Abrar Ahmad, Jennifer R. Gallagher, et al.
(2020) Diabetes, 69 p.424-435
Journal article

Effects of dipeptidyl peptidase 4 inhibition on inflammation in atherosclerosis : A ¹⁸F-fluorodeoxyglucose study of a mouse model of atherosclerosis and type 2 diabetes

Jenni Virta, Sanna Hellberg, Heidi Liljenbäck, Mia Ståhle, Johanna M.U. Silvola, et al.
(2020) Atherosclerosis, 305 p.64-72
Journal article

The 2019 FASEB Science Research Conference on Smooth Muscle, July 14-19, 2019, Palm Beach Florida, USA

Jonathan H. Jaggar, Maria F. Gomez
(2019) FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 33 p.13068-13070
Journal article

Integrative analysis of prognostic biomarkers derived from multiomics panels helps discrimination of chronic kidney disease trajectories in people with type 2 diabetes

Michael Kammer, Andreas Heinzel, Jill A. Willency, Kevin L. Duffin, Gert Mayer, et al.
(2019) Kidney International, 96 p.1381-1388
Journal article

Complement Component C3 Is Highly Expressed in Human Pancreatic Islets and Prevents β Cell Death via ATG16L1 Interaction and Autophagy Regulation

Ben King, Klaudia Kulak, Ulrika Krus, Rebecca Rosberg, Ewelina Golec, et al.
(2019) Cell Metabolism, 29 p.6-210
Journal article

In vivo inhibition of nuclear factor of activated T-cells leads to atherosclerotic plaque regression in IGF-II/LDLR ^-/-ApoB^100/100 mice

Fabiana Blanco, Suvi E Heinonen, Erika Gurzeler, Lisa M Berglund, Anna-Maria Dutius Andersson, et al.
(2018) Diabetes and Vascular Disease Research, 15 p.302-313
Journal article

MicroRNA-dependent regulation of KLF4 by glucose in vascular smooth muscle

Tran T. Hien, Eliana Garcia-Vaz, Karin G. Stenkula, Johan Sjögren, Johan Nilsson, et al.
(2018) Journal of Cellular Physiology, 233 p.7195-7205
Journal article

Validation of Plasma Biomarker Candidates for the Prediction of eGFR Decline in Patients With Type 2 Diabetes

Andreas Heinzel, Michael Kammer, Gert Mayer, Roman Reindl-Schwaighofer, Karin Hu, et al.
(2018) Diabetes Care, 41 p.1947-1954
Journal article

Orai channels are critical for receptor-mediated endocytosis of albumin

Bo Zeng, Gui Lan Chen, Eliana Garcia-Vaz, Sunil Bhandari, Nikoleta Daskoulidou, et al.
(2017) Nature Communications, 8
Journal article

Metformin treatment significantly enhances intestinal glucose uptake in patients with type 2 diabetes : Results from a randomized clinical trial

Jukka P. Koffert, Kirsi Mikkola, Kirsi A. Virtanen, Anna Maria D. Andersson, Linda Faxius, et al.
(2017) Diabetes Research and Clinical Practice, 131 p.208-216
Journal article

The impact of Roux-en-Y gastric bypass surgery on normal metabolism in a porcine model

Andreas Lindqvist, Mikael Ekelund, Eliana Garcia-Vaz, Marcus Ståhlman, Stefan Pierzynowski, et al.
(2017) PLoS ONE, 12
Journal article

Osteopontin affects insulin vesicle localization and Ca²⁺ homeostasis in pancreatic beta cells from female mice

Anna Wendt, Ines Mollet, Anki Knutsson, Victor S. Bolmgren, Anna Hultgårdh, et al.
(2017) PLoS ONE, 12
Journal article

Emerging roles of the myocardin family of proteins in lipid and glucose metabolism

Karl Swärd, Karin G. Stenkula, Catarina Rippe, Azra Alajbegovic, Maria F. Gomez, et al.
(2016) Journal of Physiology, 594 p.4741-4752
Journal article

Glucose-Dependent Insulinotropic Polypeptide (GIP) Stimulates Osteopontin Expression in the Vasculature via Endothelin-1 and CREB.

Lisa Berglund, Valeriya Lyssenko, Claes Ladenvall, Olga Kotova, Andreas Edsfeldt, et al.
(2016) Diabetes, 65 p.239-254
Journal article

Systematic study of constitutive cyclooxygenase-2 expression: Role of NF-κB and NFAT transcriptional pathways.

Nicholas S Kirkby, Melissa V Chan, Anne K Zaiss, Eliana Garcia Vaz, Jing Jiao, et al.
(2016) Proceedings of the National Academy of Sciences, 113 p.434-439
Journal article

Epigenetic regulation of the thioredoxin-interacting protein (TXNIP) gene by hyperglycemia in kidney.

Yang De Marinis, Mengyin Cai, Bompada Pradeep, David Grubich Atac, Olga Kotova, et al.
(2016) Kidney International, 89 p.342-353
Journal article

Elevated glucose levels promote contractile and cytoskeletal gene expression in vascular smooth muscle via Rho/protein kinase C and actin polymerization.

Thi Hien Tran, Karolina Turczynska, Diana Dahan, Mari Ekman, Mario Grossi, et al.
(2016) Journal of Biological Chemistry, 291 p.68-3552
Journal article

Syndecan-4 is a key determinant of collagen cross-linking and passive myocardial stiffness in the pressure-overloaded heart.

Kate Herum Möller, Ida G Lunde, Biljana Skrbic, William E Louch, Almira Hasic, et al.
(2015) Cardiovascular Research, 106 p.217-226
Journal article

Nuclear Factor of Activated T Cells Is Activated in the Endothelium of Retinal Microvessels in Diabetic Mice.

Anna Zetterqvist, Fabiana Blanco, Jenny Öhman, Olga Kotova, Lisa Berglund, et al.
(2015) Journal of Diabetes Research, 2015
Journal article

Animal Models of Diabetic Macrovascular Complications: Key Players in the Development of New Therapeutic Approaches.

Suvi E Heinonen, Guillem Genové, Eva Bengtsson, Thomas Hübschle, Lina Åkesson, et al.
(2015) Journal of Diabetes Research, 2015
Journal article review

High glucose enhances store-operated calcium entry by upregulating ORAI/STIM via calcineurin-NFAT signalling

Nikoleta Daskoulidou, Bo Zeng, Lisa Berglund, Hongni Jiang, Gui-Lan Chen, et al.
(2015) Journal of Molecular Medicine, 93 p.511-521
Journal article

Streptococcal M1 protein triggers chemokine formation, neutrophil infiltration, and lung injury in an NFAT-dependent manner.

Songen Zhang, Su Zhang, Eliana Garcia Vaz, Heiko Herwald, Maria Gomez, et al.
(2015) Journal of Leukocyte Biology, 97 p.1003-1010
Journal article

NFAT regulates neutrophil recruitment, systemic inflammation and T-cell dysfunction in abdominal sepsis.

Su Zhang, Lingtao Luo, Yongzhi Wang, Maria Gomez, Henrik Thorlacius
(2014) Infection and Immunity, 82 p.3275-3288
Journal article

The Complement Inhibitor CD59 Regulates Insulin Secretion by Modulating Exocytotic Events.

Ulrika Krus, Ben King, Vini Nagaraj, Nikhil R Gandasi, Jonatan Sjölander, et al.
(2014) Cell Metabolism, 19 p.883-890
Journal article

Gastric bypass improves ss-cell function and increases β-cell mass in a porcine model.

Andreas Lindqvist, Peter Spégel, Mikael Ekelund, Eliana Garcia Vaz, Stefan Pierzynowski, et al.
(2014) Diabetes, 63 p.1665-1671
Journal article

Syndecan-4 signaling via NFAT regulates extracellular matrix production and cardiac myofibroblast differentiation in response to mechanical stress

Kate M. Herum, Ida G. Lunde, Biljana Skrbic, Geir Florholmen, Dina Behmen, et al.
(2013) Journal of Molecular and Cellular Cardiology, 54 p.73-81
Journal article

Inhibition of nuclear factor of activated T-cells (NFAT) suppresses accelerated atherosclerosis in diabetic mice.

Anna Zetterqvist, Lisa Berglund, Fabiana Blanco, Eliana Garcia Vaz, Maria Wigren, et al.
(2013) PLoS ONE, 8
Journal article

Photocoagulation of human retinal pigment epithelial cells in vitro: evaluation of necrosis, apoptosis, cell migration, cell proliferation and expression of tissue repairing and cytoprotective genes.

Poya Tababat-Khani, Lisa Berglund, Carl-David Agardh, Maria Gomez, Elisabet Agardh
(2013) PLoS ONE, 8
Journal article

A link between GIP and osteopontin in adipose tissue and insulin resistance.

Emma Ahlqvist, Peter Osmark, Tiina Kuulasmaa, Kasper Pilgaard, Bilal Omar, et al.
(2013) Diabetes, 62 p.2088-2094
Journal article

Attenuation of Experimental Atherosclerosis by Interleukin-19.

Stephen Ellison, Khatuna Gabunia, Sheri E Kelemen, Ross N England, Rosario Scalia, et al.
(2013) Arteriosclerosis, Thrombosis and Vascular Biology, 33 p.2316-2324
Journal article

Regulation of the pro-inflammatory cytokine osteopontin by GIP in adipocytes - A role for the transcription factor NFAT and phosphodiesterase 3B.

Bilal Omar, Elin Banke, Emilia Guiguis, Lina Kesson, Vincent Manganiello, et al.
(2012) Biochemical and Biophysical Research Communications, 425 p.812-817
Journal article

Increased Inflammation in Atherosclerotic Lesions of Diabetic Akita-LDLr(-/-) Mice Compared to Nondiabetic LDLr(-/-) Mice.

Daniel Engelbertsen, Fong To, Pontus Dunér, Olga Kotova, Ingrid Söderberg, et al.
(2012) Experimental Diabetes Research, 2012
Journal article

Characterization of the Lipid Droplet Proteome of a Clonal Insulin-producing β-Cell Line (INS-1 832/13).

Sara Larsson, Svante Resjö, Maria Gomez, Peter James, Cecilia Holm
(2012) Journal of Proteome Research, 11 p.1264-1273
Journal article

NFAT regulates the expression of AIF-1 and IRT-1: Yin and yang splice variants of neointima formation and atherosclerosis.

Lisa Berglund, Olga Kotova, Peter Osmark, Helena Grufman, Chen Xing, et al.
(2012) Cardiovascular Research, 93 p.414-423
Journal article

Mobilization of regulatory T cells in response to carotid injury does not influence subsequent neointima formation.

Amit Saxena, Harry Björkbacka, Åsa Ström, Sara Rattik, Katarina Berg, et al.
(2012) PLoS ONE, 7
Journal article

NFATc3 Regulates Trypsinogen Activation, Neutrophil Recruitment, and Tissue Damage in Acute Pancreatitis in Mice.

Darbaz Awla, Anna Zetterqvist, Aree Abdulla, Cristina Camello, Lisa Berglund, et al.
(2012) Gastroenterology, 143 p.1352-1352
Journal article

The Vascular Repair Process after Injury of the Carotid Artery is regulated by IL-1RI and MyD88 Signalling.

Amit Saxena, Uwe Rauch, Katarina Berg, Linda Andersson, Lisette Hollender, et al.
(2011) Cardiovascular Research, 91 p.350-357
Journal article

Pleiotropic Effects of GIP on Islet Function Involve Osteopontin

Valeriya Lyssenko, Lena Eliasson, Olga Kotova, Kasper Pilgaard, Nils Wierup, et al.
(2011) Diabetes, 60 p.2424-2433
Journal article

Integrative genomics identifies DSCR1 (RCAN1) as a novel NFAT-dependent mediator of phenotypic modulation in vascular smooth muscle cells

Monica Y. Lee, Sean M. Garvey, Alex S. Baras, Julia A. Lemmon, Maria Gomez, et al.
(2010) Human Molecular Genetics, 19 p.468-479
Journal article

Vascular cellular adhesion molecule-1 (VCAM-1) expression in mice retinal vessels is affected by both hyperglycemia and hyperlipidemia.

Carin Gustavsson, Carl-David Agardh, Anna Zetterqvist, Jan Nilsson, Elisabet Agardh, et al.
(2010) PLoS ONE, 5
Journal article

Individual domains of Tensin2 exhibit distinct subcellular localisations and migratory effects.

Sassan Hafizi, Emma Sernstad, Jerome D Swinny, Maria Gomez, Björn Dahlbäck
(2010) International Journal of Biochemistry and Cell Biology, 42 p.52-61
Journal article

Nuclear Factor of Activated T Cells Regulates Osteopontin Expression in Arterial Smooth Muscle in Response to Diabetes-Induced Hyperglycemia.

Lisa Berglund, Anna Zetterqvist, Jenny Öhman, Mikael Sigvardsson, Laura V González Bosc, et al.
(2010) Arteriosclerosis, Thrombosis and Vascular Biology, 30 p.154-218
Journal article

Low molecular weight heparin stimulates myometrial contractility and cervical remodeling in vitro

Gunvor Ekman-Ordeberg, Margareta Hellgren, Anna Åkerud, Eva Andersson, Aurelija Dubicke, et al.
(2009) Acta Obstetricia et Gynecologica Scandinavica, 88 p.984-989
Journal article

Deletion of the G protein-coupled Receptor GPR30 Impairs Glucose Tolerance, Reduces Bone Growth, Increases Blood Pressure, and Eliminates Estradiol-stimulated Insulin Release in Female Mice.

Ulrika Mårtensson, S Albert Salehi, Sara Windahl, Maria Gomez, Karl Swärd, et al.
(2009) Endocrinology, 150 p.687-698
Journal article

Tumor necrosis factor-alpha does not mediate diabetes-induced vascular inflammation in mice.

Jenny Öhman, Gunilla Nordin Fredrikson, Lisa Berglund, Carin Gustavsson, Eva Bengtsson, et al.
(2009) Arteriosclerosis, Thrombosis and Vascular Biology, 29 p.1465-1470
Journal article

Molecular Mechanisms of Collagen Isotype-Specific Modulation of Smooth Muscle Cell Phenotype.

A Wayne Orr, Monica Y Lee, Julia A Lemmon, Arif Yurdagul, Maria Gomez, et al.
(2009) Arteriosclerosis, Thrombosis and Vascular Biology, Nov 20 p.225-231
Journal article

Integrative Genomics Identifies DSCR1 (RCAN1) as a Novel NFAT-Dependent Mediator of Phenotypic Modulation in Vascular Smooth Muscle Cells

Monica Y. Lee, Sean M. Garvey, Alex S. Baras, Julia A. Lemmon, Maria Gomez, et al.
(2009) Arteriosclerosis, Thrombosis, and Vascular Biology, 29 p.57-58
Conference paper: abstract

Diet-Induced Hyperlipidemia Activates Myd88-Dependent Innate Immune Signaling Resulting In Increased Leukocyte Rolling In Vivo

Adrian Pistea, Katarina Berg, Marie Lindholm, Anna Zetterqvist, Jenny Öhman, et al.
(2009) Atherosclerosis Supplements, 10
Conference paper: abstract

Nuclear factor of activated T-cells transcription factors in the vasculature: the good guys or the bad guys?

Lisa Berglund, Jenny Öhman, Anna Zetterqvist, Maria Gomez
(2008) Current Opinion in Lipidology, 19 p.483-490
Journal article

Melatonin restores impaired contractility in aged guinea pig urinary bladder

Pedro J Gomez-Pinilla, Maria Gomez, Karl Swärd, Petter Hedlund, Per Hellstrand, et al.
(2008) Journal of Pineal Research, 44 p.416-425
Journal article

The importance of fibroblasts in remodelling of the human uterine cervix during pregnancy and parturition.

Erik Malmström, Maria Sennstrom, Anna Holmberg, Helena Frielingsdorf, Erik Eklund, et al.
(2007) Molecular Human Reproduction, 13 p.333-341
Journal article

Effect of melatonin on age associated changes in guinea pig bladder function

Pedro J. Gomez-Pinilla, Maria Gomez, Petter Hedlund, Karl Swärd, Per Hellstrand, et al.
(2007) Journal of Urology, 177 p.1558-1561
Journal article

Novel blocker of NFAT activation inhibits IL-6 production in human myometrial arteries and reduces vascular smooth muscle cell proliferation

Lisa Berglund, Zhengwu Sun, Jenny Nilsson, Ina Nordström, Yung-Wu Chen, et al.
(2007) American Journal of Physiology: Cell Physiology, 292 p.1167-1178
Journal article

Involvement of the CD1d-Natural killer T cell pathway in neointima formation after vascular injury

Åsa Ström, Maria Wigren, Anna Hultgårdh, Amit Saxena, Maria Gomez, et al.
(2007) Circulation Research, 101 p.83-89
Journal article

High glucose activates nuclear factor of activated T cells in native vascular smooth muscle

Jenny Öhman, Lisa Berglund, YW Chen, JD Molkentin, David Erlinge, et al.
(2006) Arteriosclerosis, Thrombosis and Vascular Biology, 26 p.794-800
Journal article

Upregulated TRPC1 Channel in Vascular Injury In Vivo and Its Role in Human Neointimal Hyperplasia.

B Kumar, Karl Dreja, S Shah, A Cheong, S-Z Xu, et al.
(2006) Circulation Research, 98 p.557-563
Journal article

Plasticity of TRPC expression in arterial smooth muscle: correlation with store-operated Ca2+ entry.

Andreas Bergdahl, Maria Gomez, Anna-Karin Wihlborg, David Erlinge, Atli Eyjolfson, et al.
(2005) American Journal of Physiology: Cell Physiology, 288 p.872-880
Journal article

Novel PPAR gamma agonists GI 262570, GW 7845, GW 1929, and pioglitazone decrease calcium channel function and myogenic tone in rat mesenteric arteries

TJ Heppner, AD Bonev, DM Eckman, Maria Gomez, GV Petkov, et al.
(2005) Pharmacology, 73 p.15-22
Journal article

c-Myc antisense oligonucleotides preserve smooth muscle differentiation and reduce negative remodelling following rat carotid arteriotomy

A Forte, U Galderisi, M De Feo, Maria Gomez, S Esposito, et al.
(2005) Journal of Vascular Research, 42 p.214-225
Journal article

NFAT regulation in smooth muscle

DC Hill-Eubanks, Maria Gomez, AS Stevenson, MT Nelson
(2003) Trends in Cardiovascular Medicine, 13 p.56-62
Journal article review

Cholesterol depletion impairs vascular reactivity to endothelin-1 by reducing store-operated Ca2+ entry dependent on TRPC1.

Andreas Bergdahl, Maria Gomez, Karl Dreja, Shang-Zhong Xu, Mikael Adner, et al.
(2003) Circulation Research, 93 p.839-847
Journal article

Constitutively elevated nuclear export activity opposes Ca2+-dependent NFATc3 nuclear accumulation in vascular smooth muscle: role of JNK2 and Crm-1

Maria Gomez, Laura V Gonzalez Bosc, Andra S Stevenson, M Keith Wilkerson, David C Hill-Eubanks, et al.
(2003) Journal of Biological Chemistry, 278 p.46847-46853
Journal article

Opposing actions of inositol 1,4,5-trisphosphate and ryanodine receptors on nuclear factor of activated T-cells regulation in smooth muscle

Maria Gomez, Andra S Stevenson, Adrian D Bonev, David C Hill-Eubanks, Mark T Nelson
(2002) Journal of Biological Chemistry, 277 p.37756-37764
Journal article

Regulation of Ca2+ channel and phosphatase activities by polyamines in intestinal and vascular smooth muscle - implications for cellular growth and contractility.

Bengt-Olof Nilsson, Maria Gomez, Karl Swärd, Per Hellstrand
(2002) Acta Physiologica Scandinavica, 176 p.33-41
Journal article

Maria Gomez

Publications