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Luis Sarmiento-Pérez

Assistant researcher

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Seroprevalencia de anticuerpos a virus del sarampión, rubeola, parotiditis, hepatitis B y los tres serotipos de poliovirus, en niños de Quindío, Colombia

Seroprevalence of antibodies to measles, rubella, mumps, hepatitis B viruses and all three poliovirus serotypes among children in Quindío, Colombia

Author

  • María M. González
  • Luis Sarmiento-Pérez
  • Alejandra M. Giraldo
  • Leonardo Padilla
  • Gloria Rey-Benito
  • Jhon C. Castaño

Summary, in English

Objective: The main goal of this research was to assess the seroprevalence of antibodies against measles, rubella, mumps, hepatitis B and all three poliovirus serotypes among children in the Quindio Department, Colombia. Methods: Blood samples were obtained from 170 healthy children aged 5-9 years from nine municipalities in Quindio. The presence of serum IgG antibodies against measles, rubella, mumps and Hepatitis B were determined using commercial indirect ELISA kits. Immunity to poliomyelitis was assessed through the presence of neutralizing antibodies following the method recommended by the World Health Organization. Results: Among the 170 children enrolled, 169 (99.41%), 170(100 %), and 167 (98.2 %) were seropositive to poliovirus 1, poliovirus 2, and poliovirus 3, respectively. The average reciprocal antibody titers were 178 for poliovirus type 1, 120 for type 2 and 56 for type 3. Of the 170 children, 96.47 % were protected against mumps and rubella, and 86.47 % against measles. Only 106 (62.35 %) of the studied subjects were proved to be seropositive to hepatitis B. Conclusion: The immunization program in Quindio has provided seroprotection against all three poliomyelitis serotypes, rubella and mumps. However, the child population is not fully protected against measles and hepatitis B virus infections.

Department/s

  • Department of Clinical Sciences, Lund
  • EXODIAB: Excellence of Diabetes Research in Sweden

Publishing year

2016-01-01

Language

Spanish

Pages

95-103

Publication/Series

Revista de Salud Publica

Volume

18

Issue

1

Document type

Journal article

Publisher

Universidad Nacional de Colombia

Topic

  • Public Health, Global Health, Social Medicine and Epidemiology

Keywords

  • Hepatitis B
  • Measles
  • Poliomyelitis
  • Seroepidemiologic studies
  • Vaccines

Status

Published

ISBN/ISSN/Other

  • ISSN: 0124-0064