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Luis Sarmiento-Pérez

Assistant researcher

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Coxsackievirus A6 and enterovirus 71 causing hand, foot and mouth disease in Cuba, 2011-2013

Author

  • Magilé C Fonseca
  • Luis Sarmiento
  • Sonia Resik
  • Yenisleidys Martínez
  • Lai Heng Hung
  • Luis Morier
  • Alexander Piñón
  • Odalys Valdéz
  • Vivian Kourí
  • Guelsys González

Summary, in English

Hand, foot and mouth disease (HFMD) is usually caused by coxsackievirus A16 or enterovirus 71 (EV71). Between 2011 and 2013, HFMD cases were reported from different Cuban provinces. A total of 42 clinical specimens were obtained from 23 patients. Detection, identification and phylogenetic analysis of enterovirus-associated HFMD were carried out by virus isolation, specific enterovirus PCR and partial VP1 sequences. HEV was detected in 11 HFMD cases. Emerging genetic variants of coxsackievirus A6 and EV71 were identified as the causative agents of the Cuban HFMD cases.

Publishing year

2014-09

Language

English

Pages

5-2451

Publication/Series

Archives of Virology

Volume

159

Issue

9

Document type

Journal article

Publisher

Springer

Topic

  • Other Clinical Medicine

Keywords

  • Adult
  • Child
  • Child, Preschool
  • Cluster Analysis
  • Cuba/epidemiology
  • Enterovirus/classification
  • Enterovirus A, Human/classification
  • Hand, Foot and Mouth Disease/epidemiology
  • Humans
  • Infant
  • Molecular Sequence Data
  • Phylogeny
  • RNA, Viral/genetics
  • Sequence Analysis, DNA
  • Sequence Homology
  • Viral Structural Proteins/genetics

Status

Published

ISBN/ISSN/Other

  • ISSN: 1432-8798