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Luis Sarmiento-Pérez

Assistant researcher

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Circulación silenciosa de poliovirus demostrada por interferencia a los enterovirus no polio

Silent circulation of poliovirus demonstrated by interference against non-polio enterovirus

Author

  • Pedro Más Lago
  • Luis Sarmiento
  • Janepsy Diáz
  • Angel Goyenechea
  • Manuel Diáz
  • Julio Barrio

Summary, in English

Fecal samples were weekly obtained from children under 3 years of age to isolate non-polio poliovirus and enterovirus and to expand the knowledge on circulation of vaccine-derived viruses during mass campaigns. The steady vaccination schedules allow the circulation of these viruses for long periods of time. The interference of non-polio enterovirus by vaccine poliovirus was demonstrated in children. However, the low percentages of non-polio enterovirus did not show significant differences whereas these differences were significant in high percentages of vaccine poliovirus isolated in children under one year-old in comparison with those of 1 and 2 years of age. Based on this contradiction, mathematical calculations estimated the silent circulation of poliovirus that in turn made it possible to draw simulated curves. The results were later confirmed in another research work by using immunological methods.

Publishing year

2004-04-26

Language

Spanish

Pages

25-117

Publication/Series

Revista cubana de medicina tropical

Volume

56

Issue

2

Document type

Journal article

Publisher

Editorial Ciencias Medicas

Topic

  • Infectious Medicine

Keywords

  • Child, Preschool
  • Enterovirus/isolation & purification
  • Feces/virology
  • Humans
  • Infant
  • Poliovirus/isolation & purification
  • Poliovirus Vaccines

Status

Published

ISBN/ISSN/Other

  • ISSN: 0375-0760