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Leif Groop

Leif Groop

Principal investigator

Leif Groop

Differentiation of diabetes by pathophysiology, natural history, and prognosis

Author

  • Jay S Skyler
  • George L. Bakris
  • Ezio Bonifacio
  • Tamara Darsow
  • Robert H. Eckel
  • Leif Groop
  • Per-Henrik Groop
  • Yehuda Handelsman
  • Richard A Insel
  • Chantal Mathieu
  • Allison T. McElvaine
  • Jerry P. Palmer
  • Alberto Pugliese
  • Desmond A Schatz
  • Jay M Sosenko
  • John P H Wilding
  • Robert E Ratner

Summary, in English

The American Diabetes Association, JDRF, the European Association for the Study of Diabetes, and the American Association of Clinical Endocrinologists convened a research symposium, "The Differentiation of Diabetes by Pathophysiology, Natural History and Prognosis" on 10-12 October 2015. International experts in genetics, immunology, metabolism, endocrinology, and systems biology discussed genetic and environmental determinants of type 1 and type 2 diabetes risk and progression, as well as complications. The participants debated how to determine appropriate therapeutic approaches based on disease pathophysiology and stage and defined remaining research gaps hindering a personalized medical approach for diabetes to drive the field to address these gaps. The authors recommend a structure for data stratification to define the phenotypes and genotypes of subtypes of diabetes that will facilitate individualized treatment.

Department/s

  • Genomics, Diabetes and Endocrinology
  • EXODIAB: Excellence of Diabetes Research in Sweden

Publishing year

2017-02-01

Language

English

Pages

241-255

Publication/Series

Diabetes

Volume

66

Issue

2

Document type

Journal article review

Publisher

American Diabetes Association Inc.

Topic

  • Endocrinology and Diabetes

Status

Published

Research group

  • Genomics, Diabetes and Endocrinology

ISBN/ISSN/Other

  • ISSN: 0012-1797