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Leif Groop

Leif Groop

Principal investigator

Leif Groop

Assessment of exercise capacity in women with type 2 diabetes.


  • Åsa Tornberg
  • Forouzan Glans
  • Karl-Fredrik Eriksson
  • Leif Groop
  • Ola Thorsson
  • Per Wollmer

Summary, in English

The primary aim of this study was to compare the maximal oxygen uptake as evaluated from a submaximal exercise test (EVO(2peak)) to direct measurements of VO(2peak) during a maximal exercise test as means of monitoring the aerobic endurance capacity in women with type 2 diabetes (T2D). Twenty-seven women with T2D participated in the study. The program consisted of combined group training 1 h twice a week during 12 weeks and walks 1 h per week. EVO(2 max) was estimated using a submaximal exercise test on a bicycle ergometer ad modumAstrand. VO(2peak) and maximal work rate were measured using an incremental maximal exercise test on an electrically braked bicycle ergometer at baseline and after 6 and 12 weeks. EVO(2peak)was higher than VO(2peak)at baseline and significantly higher at 12 weeks (EVO(2peak)1.92 +/- 0.54 l min(-1), VO(2peak) 1.41 +/- 0.36, P < 0.005). Maximal work rate increased significantly after 12 weeks (12 +/- 15, P < 0.005) compared to baseline. The main finding of this study was that EVO(2peak) assessed using a submaximal exercise test, systematically overestimated VO(2peak). The combined group training increased maximal work rate but not VO(2peak). This is likely to reflect peripheral adaptation to exercise and/or improved mechanical efficiency.


  • Human Movement: health and rehabilitation
  • Genomics, Diabetes and Endocrinology
  • Vascular Diseases - Clinical Research
  • Clinical Physiology, Malmö

Publishing year







Clinical Physiology and Functional Imaging



Document type

Journal article


John Wiley and Sons


  • Physiology



Research group

  • Physiotherapy
  • Genomics, Diabetes and Endocrinology
  • Vascular Diseases - Clinical Research
  • Clinical Physiology, Malmö


  • ISSN: 1475-0961