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Karl-Fredrik Eriksson

Associate professor

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Extensive acute deep vein thrombosis of the iliocaval segment: midterm results of thrombolysis and stent placement.

Author

  • Tilo Kölbel
  • Mats Lindh
  • Jan Holst
  • Petr Uher
  • Karl-Fredrik Eriksson
  • Björn Sonesson
  • Martin Malina
  • Krasnodar Ivancev

Summary, in English

PURPOSE: To evaluate patency and clinical outcome in patients treated with catheter-directed thrombolysis and stent placement for acute extensive thrombosis affecting the iliocaval segment. MATERIALS AND METHODS: During a 10-year period (1994-2005), 37 patients with 44 limbs (26 female, median age 31 years) with acute extensive venous thrombosis affecting the iliocaval segment were treated with catheter-directed thrombolysis. Angioplasty and stent placement was performed in 36 limbs (82%) for underlying stenosis or residual thrombosis. A prospectively registered database was analyzed in combination with a telephone interview about clinical symptoms. RESULTS: Technical success was achieved in all 44 limbs and clinical success in 42 of 44 (96%) limbs. Primary patency after a median imaging follow-up interval of 16 months was 34 of 44 (77%) limbs, assisted primary patency was 38 of 44 (86%) limbs, and secondary patency was 39 of 44 (89%) limbs. Thirty of 44 (68%) limbs were asymptomatic after a median clinical follow-up of 27 months, eight (18%) limbs were moderately improved, two (5%) limbs were unchanged, two (5%) limbs were moderately worse, and two (5%) limbs had no clinical follow-up. Complications occurred in six (16%) patients, three (8%) of which were major complications. No patient developed symptomatic pulmonary embolism. CONCLUSIONS: Catheter-directed thrombolysis and stent placement is a safe and effective treatment for acute iliocaval thrombosis. Clinical midterm results are encouraging. Thrombolyzed and stented segments remain patent in the vast majority of patients after 16 months. Primary and aggressive stent placement in the iliocaval vein segments can prevent rethrombosis and ensure patency.

Department/s

  • Department of Clinical Sciences, Malmö
  • Vascular Diseases - Clinical Research
  • Radiology Diagnostics, Malmö

Publishing year

2007

Language

English

Pages

243-250

Publication/Series

Journal of Vascular and Interventional Radiology

Volume

18

Issue

2

Document type

Journal article

Publisher

Society of Interventional Radiology

Topic

  • Clinical Medicine
  • Radiology, Nuclear Medicine and Medical Imaging
  • Cardiac and Cardiovascular Systems

Status

Published

Research group

  • Vascular Diseases - Clinical Research
  • Radiology Diagnostics, Malmö

ISBN/ISSN/Other

  • ISSN: 1051-0443