Jonathan Esguerra, Head, Bioinformatics and management
Publications
Retrieved from Lund University's publications database
Publications
- 2019
- Defective exocytosis and processing of insulin in a cystic fibrosis mouse model
(2019) Journal of Endocrinology
Journal article - In Vivo Silencing of MicroRNA-132 Reduces Blood Glucose and Improves Insulin Secretion
(2019) Nucleic acid therapeutics
Journal article
- Defective exocytosis and processing of insulin in a cystic fibrosis mouse model
- 2018
- Islet microRNAs in health and type-2 diabetes
(2018) Current Opinion in Pharmacology
Journal article review - MicroRNAs in islet hormone secretion
(2018) Diabetes, Obesity and Metabolism
Journal article review - miR-483-5p associates with obesity and insulin resistance and independently associates with new onset diabetes mellitus and cardiovascular disease
(2018) PLoS ONE
Journal article
- Islet microRNAs in health and type-2 diabetes
- 2017
- CD36 is increased in human islets from obese type 2 diabetes donors, and affects beta cell function by the modulation of exocytotic proteins and insulin content
(2017) Diabetologia
Conference paper: abstract - Confluence does not affect the expression of miR-375 and its direct targets in rat and human insulin-secreting cell lines
(2017) PeerJ
Journal article - Elevated miR-130a/miR130b/miR-152 expression reduces intracellular ATP levels in the pancreatic beta cell
(2017) Scientific Reports
Journal article - Endogenous beta-cell CART regulates insulin secretion and transcription of beta-cell genes
(2017) Molecular and Cellular Endocrinology
Journal article - Glucotoxicity-induced upregulation of lincRNA GAS5 in the pancreatic islets of type 2 diabetes donors and in Goto-Kakizaki rats
(2017) Diabetologia
Conference paper: abstract - Identification of islet-enriched long non-coding RNAs contributing to β-cell failure in type 2 diabetes
(2017) Molecular Metabolism
Journal article - Lessons from basic pancreatic beta cell research in type-2 diabetes and vascular complications
(2017) Diabetology International
Journal article review - MiR-335 overexpression impairs insulin secretion through defective priming of insulin vesicles
(2017) Physiological Reports
Journal article - Neuron-enriched RNA-binding Proteins Regulate Pancreatic Beta Cell Function and Survival
(2017) Journal of Biological Chemistry
Journal article - Reduced insulin secretion in a diet-induced glucose intolerance susceptible mouse model is coupled with increased CD36 and triglycerides in the beta cells
(2017)
Conference paper: abstract - Whole-genome Bisulfite Sequencing of Human Pancreatic Islets Reveals Novel Differentially Methylated Regions in Type 2 Diabetes Pathogenesis
(2017) Diabetes
Journal article
- CD36 is increased in human islets from obese type 2 diabetes donors, and affects beta cell function by the modulation of exocytotic proteins and insulin content
- 2016
- CD46 Activation Regulates miR-150-Mediated Control of GLUT1 Expression and Cytokine Secretion in Human CD4+ T Cells.
(2016) Journal of immunology (Baltimore, Md. : 1950)
Journal article - Dual Effect of Rosuvastatin on Glucose Homeostasis Through Improved Insulin Sensitivity and Reduced Insulin Secretion
(2016) EBioMedicine
Journal article - Transcriptional regulation of the miR-212/miR-132 cluster in insulin-secreting β-cells by cAMP-regulated transcriptional co-activator 1 and salt-inducible kinases.
(2016) Molecular and Cellular Endocrinology
Journal article
- CD46 Activation Regulates miR-150-Mediated Control of GLUT1 Expression and Cytokine Secretion in Human CD4+ T Cells.
- 2015
- MiR-335 regulates exocytotic proteins and affects glucose-stimulated insulin secretion through decreased Ca2+-dependent exocytosis in beta cells
(2015) Diabetologia
Conference paper: abstract - Modulation of microRNA-375 expression alters voltage-gated Na(+) channel properties and exocytosis in insulin-secreting cells.
(2015) Acta Physiologica
Journal article
- MiR-335 regulates exocytotic proteins and affects glucose-stimulated insulin secretion through decreased Ca2+-dependent exocytosis in beta cells
- 2014
- Argonaute2 Mediates Compensatory Expansion of the Pancreatic β Cell.
(2014) Cell Metabolism
Journal article - CFTR and Anoctamin 1 (ANO1) contribute to cAMP amplified exocytosis and insulin secretion in human and murine pancreatic beta-cells.
(2014) BMC Medicine
Journal article - Functional implications of long non-coding RNAs in the pancreatic islets of Langerhans.
(2014) Frontiers in Genetics
Journal article review - Global genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolism.
(2014) Proceedings of the National Academy of Sciences
Journal article - MicroRNA-7a regulates pancreatic beta cell function
(2014) Journal of Clinical Investigation
Journal article - Nova1 is a master regulator of alternative splicing in pancreatic beta cells.
(2014) Nucleic Acids Research
Journal article - Regulation of Pancreatic Beta Cell Stimulus-Secretion Coupling by microRNAs.
(2014) Genes
Journal article review - Role of non-coding RNAs in pancreatic beta-cell development and physiology.
(2014) Acta Physiologica
Journal article review - Sex differences in the genome-wide DNA methylation pattern and impact on gene expression, microRNA levels and insulin secretion in human pancreatic islets
(2014) GenomeBiology
Journal article
- Argonaute2 Mediates Compensatory Expansion of the Pancreatic β Cell.
- 2012
- A systems genetics approach identifies genes and pathways for type 2 diabetes in human islets.
(2012) Cell Metabolism
Journal article - CD46 costimulation leads to enhanced T cell activation and microrna expression
(2012) Immunobiology
Conference paper: abstract - Secreted frizzled-related protein 4 reduces insulin secretion and is overexpressed in type 2 diabetes.
(2012) Cell Metabolism
Journal article
- A systems genetics approach identifies genes and pathways for type 2 diabetes in human islets.
- 2011
- Beta-cell specific deletion of dicer1 leads to defective insulin secretion and diabetes mellitus.
(2011) PLoS ONE
Journal article - Differences in islet-enriched miRNAs in healthy and glucose intolerant human subjects.
(2011) Biochemical and Biophysical Research Communications
Journal article - Differential Glucose-Regulation of MicroRNAs in Pancreatic Islets of Non-Obese Type 2 Diabetes Model Goto-Kakizaki Rat.
(2011) PLoS ONE
Journal article
- Beta-cell specific deletion of dicer1 leads to defective insulin secretion and diabetes mellitus.
- 2010
- MicroRNA differences in human islets and glucose-sensitive tissues
(2010) Diabetologia
Conference paper: abstract
- MicroRNA differences in human islets and glucose-sensitive tissues
- 2009
- Predicted targets of co-expressed microRNAs in pancreatic islets of GK rats are enriched for genes involved in regulation of beta cell mass and glucose-stimulated insulin secretion
(2009) Diabetologia
Conference paper: abstract
- Predicted targets of co-expressed microRNAs in pancreatic islets of GK rats are enriched for genes involved in regulation of beta cell mass and glucose-stimulated insulin secretion
- 2008
Assistant researcher