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Jonathan Esguerra, Head, Bioinformatics and management

Publications

Retrieved from Lund University's publications database

Latest

All

Publications

Retrieved from Lund University's publications database

2019
- Defective exocytosis and processing of insulin in a cystic fibrosis mouse model
  Anna Edlund, Mohammad Barghouth, Michael Huhn, Mia Abels, Jonathan Esguerra, et al.
  (2019) Journal of Endocrinology
  Journal article
- In Vivo Silencing of MicroRNA-132 Reduces Blood Glucose and Improves Insulin Secretion
  Roel Bijkerk, Jonathan L S Esguerra, Johanne H Ellenbroek, Yu Wah Au, Maaike A J Hanegraaf, et al.
  (2019) Nucleic acid therapeutics
  Journal article
2018
- Islet microRNAs in health and type-2 diabetes
  Anna Wendt, Jonathan LS Esguerra, Lena Eliasson
  (2018) Current Opinion in Pharmacology
  Journal article review
- MicroRNAs in islet hormone secretion
  Jonathan L.S. Esguerra, Mototsugu Nagao, Jones K. Ofori, Anna Wendt, Lena Eliasson
  (2018) Diabetes, Obesity and Metabolism
  Journal article review
- miR-483-5p associates with obesity and insulin resistance and independently associates with new onset diabetes mellitus and cardiovascular disease
  Widet Gallo, Jonathan Lou S. Esguerra, Lena Eliasson, Olle Melander
  (2018) PLoS ONE
  Journal article
2017
- CD36 is increased in human islets from obese type 2 diabetes donors, and affects beta cell function by the modulation of exocytotic proteins and insulin content
  M. Nagao, J. L. S. Esguerra, J. K. Ofori, A. Wendt, A. Asai, et al.
  (2017) Diabetologia
  Conference paper: abstract
- Confluence does not affect the expression of miR-375 and its direct targets in rat and human insulin-secreting cell lines
  Jones K Ofori, Helena A Malm, Ines G Mollet, Lena Eliasson, Jonathan Lou S Esguerra
  (2017) PeerJ
  Journal article
- Elevated miR-130a/miR130b/miR-152 expression reduces intracellular ATP levels in the pancreatic beta cell
  Jones K. Ofori, Vishal A. Salunkhe, Annika Bagge, Neelanjan Vishnu, Mototsugu Nagao, et al.
  (2017) Scientific Reports
  Journal article
- Endogenous beta-cell CART regulates insulin secretion and transcription of beta-cell genes
  L Shcherbina, A Edlund, J L S Esguerra, M Abels, Y Zhou, et al.
  (2017) Molecular and Cellular Endocrinology
  Journal article
- Glucotoxicity-induced upregulation of lincRNA GAS5 in the pancreatic islets of type 2 diabetes donors and in Goto-Kakizaki rats
  J. L. S. Esguerra, J. Ofori, M. Nagao, J. Fadista, L. Groop, et al.
  (2017) Diabetologia
  Conference paper: abstract
- Identification of islet-enriched long non-coding RNAs contributing to β-cell failure in type 2 diabetes
  Anna Motterle, Sonia Gattesco, Marie Line Peyot, Jonathan Lou S. Esguerra, Ana Ruiz-Gomez, et al.
  (2017) Molecular Metabolism
  Journal article
- Lessons from basic pancreatic beta cell research in type-2 diabetes and vascular complications
  Lena Eliasson, Jonathan Lou S. Esguerra, Anna Wendt
  (2017) Diabetology International
  Journal article review
- MiR-335 overexpression impairs insulin secretion through defective priming of insulin vesicles
  Vishal A. Salunkhe, Jones K. Ofori, Nikhil R. Gandasi, Sofia A. Salö, Sofia Hansson, et al.
  (2017) Physiological Reports
  Journal article
- Neuron-enriched RNA-binding Proteins Regulate Pancreatic Beta Cell Function and Survival
  Jon Agraves Juan-Mateu, Tatiana H Rech, Olatz Villate, Esther Lizarraga-Mollinedo, Anna Wendt, et al.
  (2017) Journal of Biological Chemistry
  Journal article
- Reduced insulin secretion in a diet-induced glucose intolerance susceptible mouse model is coupled with increased CD36 and triglycerides in the beta cells
  A. Asai, M. Nagao, T. Tsuduki, T. Miyazawa, J. L. S. Esguerra, et al.
  (2017)
  Conference paper: abstract
- Whole-genome Bisulfite Sequencing of Human Pancreatic Islets Reveals Novel Differentially Methylated Regions in Type 2 Diabetes Pathogenesis
  Petr Volkov, Karl Bacos, Jones K Ofori, Jonathan Lou S Esguerra, Lena Eliasson, et al.
  (2017) Diabetes
  Journal article
2016
- CD46 Activation Regulates miR-150-Mediated Control of GLUT1 Expression and Cytokine Secretion in Human CD4+ T Cells.
  Ben King, Jonathan Esguerra, Ewelina Golec, Lena Eliasson, Claudia Kemper, et al.
  (2016) Journal of immunology (Baltimore, Md. : 1950)
  Journal article
- Dual Effect of Rosuvastatin on Glucose Homeostasis Through Improved Insulin Sensitivity and Reduced Insulin Secretion
  Vishal A. Salunkhe, Ines Mollet, Jones K. Ofori, Helena A. Malm, Jonathan L S Esguerra, et al.
  (2016) EBioMedicine
  Journal article
- Transcriptional regulation of the miR-212/miR-132 cluster in insulin-secreting β-cells by cAMP-regulated transcriptional co-activator 1 and salt-inducible kinases.
  Helena Malm, Ines Mollet, Christine Berggreen, Marju Orho-Melander, Jonathan Esguerra, et al.
  (2016) Molecular and Cellular Endocrinology
  Journal article
2015
- MiR-335 regulates exocytotic proteins and affects glucose-stimulated insulin secretion through decreased Ca2+-dependent exocytosis in beta cells
  V.A. Salunkhe, J. Ofori, N.R. Gandasi, S.A. Salö, A. Wendt, et al.
  (2015) Diabetologia
  Conference paper: abstract
- Modulation of microRNA-375 expression alters voltage-gated Na(+) channel properties and exocytosis in insulin-secreting cells.
  Vishal Ashok Salunkhe, Jonathan Esguerra, Jones Ofori, Ines Mollet, Matthias Braun, et al.
  (2015) Acta Physiologica
  Journal article
2014
- Argonaute2 Mediates Compensatory Expansion of the Pancreatic β Cell.
  Sudhir G Tattikota, Thomas Rathjen, Sarah J McAnulty, Hans-Hermann Wessels, Ildem Akerman, et al.
  (2014) Cell Metabolism
  Journal article
- CFTR and Anoctamin 1 (ANO1) contribute to cAMP amplified exocytosis and insulin secretion in human and murine pancreatic beta-cells.
  Anna Edlund, Jonathan Esguerra, Anna Wendt, Malin Flodström-Tullberg, Lena Eliasson
  (2014) BMC Medicine
  Journal article
- Functional implications of long non-coding RNAs in the pancreatic islets of Langerhans.
  Jonathan Esguerra, Lena Eliasson
  (2014) Frontiers in Genetics
  Journal article review
- Global genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolism.
  Joao Fadista, Petter Vikman, Emilia Ottosson Laakso, Ines Mollet, Jonathan Esguerra, et al.
  (2014) Proceedings of the National Academy of Sciences
  Journal article
- MicroRNA-7a regulates pancreatic beta cell function
  Mathieu Latreille, Jean Hausser, Ina Stuetzer, Quan Zhang, Benoit Hastoy, et al.
  (2014) Journal of Clinical Investigation
  Journal article
- Nova1 is a master regulator of alternative splicing in pancreatic beta cells.
  Olatz Villate, Jean-Valery Turatsinze, Loriana G Mascali, Fabio A Grieco, Tatiane C Nogueira, et al.
  (2014) Nucleic Acids Research
  Journal article
- Regulation of Pancreatic Beta Cell Stimulus-Secretion Coupling by microRNAs.
  Jonathan Esguerra, Ines Mollet, Vishal Ashok Salunkhe, Anna Wendt, Lena Eliasson
  (2014) Genes
  Journal article review
- Role of non-coding RNAs in pancreatic beta-cell development and physiology.
  Lena Eliasson, Jonathan Esguerra
  (2014) Acta Physiologica
  Journal article review
- Sex differences in the genome-wide DNA methylation pattern and impact on gene expression, microRNA levels and insulin secretion in human pancreatic islets
  Elin Hall, Petr Volkov, Tasnim Dayeh, Jonathan Esguerra, Sofia Salo, et al.
  (2014) GenomeBiology
  Journal article
2012
- A systems genetics approach identifies genes and pathways for type 2 diabetes in human islets.
  Jalal Taneera, Stefan Lang, Amitabh Sharma, Joao Fadista, Yuedan Zhou, et al.
  (2012) Cell Metabolism
  Journal article
- CD46 costimulation leads to enhanced T cell activation and microrna expression
  Benjamin C. King, Jonathan Esguerra, Munazza Qayyum, Lena Eliasson, Claudia Kemper, et al.
  (2012) Immunobiology
  Conference paper: abstract
- Secreted frizzled-related protein 4 reduces insulin secretion and is overexpressed in type 2 diabetes.
  Taman Mahdi, Sonja Hänzelmann, S Albert Salehi, Sarheed Jabar Muhammed, Thomas Reinbothe, et al.
  (2012) Cell Metabolism
  Journal article
2011
- Beta-cell specific deletion of dicer1 leads to defective insulin secretion and diabetes mellitus.
  Martins Kalis, Caroline Bolmeson, Jonathan Esguerra, Shashank Gupta, Anna Edlund, et al.
  (2011) PLoS ONE
  Journal article
- Differences in islet-enriched miRNAs in healthy and glucose intolerant human subjects.
  Caroline Bolmeson, Jonathan Esguerra, S Albert Salehi, Dina Speidel, Lena Eliasson, et al.
  (2011) Biochemical and Biophysical Research Communications
  Journal article
- Differential Glucose-Regulation of MicroRNAs in Pancreatic Islets of Non-Obese Type 2 Diabetes Model Goto-Kakizaki Rat.
  Jonathan Esguerra, Caroline Bolmeson, Corrado Cilio, Lena Eliasson
  (2011) PLoS ONE
  Journal article
2010
- MicroRNA differences in human islets and glucose-sensitive tissues
  Caroline Bolmeson, Jonathan Esguerra, Dina Speidel, Lena Eliasson, Corrado Cilio
  (2010) Diabetologia
  Conference paper: abstract
2009
- Predicted targets of co-expressed microRNAs in pancreatic islets of GK rats are enriched for genes involved in regulation of beta cell mass and glucose-stimulated insulin secretion
  Jonathan Esguerra, Caroline Bolmeson, Corrado Cilio, Lena Eliasson
  (2009) Diabetologia
  Conference paper: abstract
2008
- Functional importance of individual rRNA 2'-O-ribose methylations revealed by high-resolution phenotyping
  Jonathan Esguerra, J. Warringer, A. Blomberg
  (2008) RNA
  Journal article

Publications

Retrieved from Lund University's publications database

Conference paper: abstract
- Reduced insulin secretion in a diet-induced glucose intolerance susceptible mouse model is coupled with increased CD36 and triglycerides in the beta cells
  A. Asai, M. Nagao, T. Tsuduki, T. Miyazawa, J. L. S. Esguerra, et al.
  (2017) , p.61-61
- Glucotoxicity-induced upregulation of lincRNA GAS5 in the pancreatic islets of type 2 diabetes donors and in Goto-Kakizaki rats
  J. L. S. Esguerra, J. Ofori, M. Nagao, J. Fadista, L. Groop, et al.
  (2017) Diabetologia, 60 p.22-23
- CD36 is increased in human islets from obese type 2 diabetes donors, and affects beta cell function by the modulation of exocytotic proteins and insulin content
  M. Nagao, J. L. S. Esguerra, J. K. Ofori, A. Wendt, A. Asai, et al.
  (2017) Diabetologia, 60 p.185-186
- MiR-335 regulates exocytotic proteins and affects glucose-stimulated insulin secretion through decreased Ca2+-dependent exocytosis in beta cells
  V.A. Salunkhe, J. Ofori, N.R. Gandasi, S.A. Salö, A. Wendt, et al.
  (2015) Diabetologia, 58 p.128-128
- CD46 costimulation leads to enhanced T cell activation and microrna expression
  Benjamin C. King, Jonathan Esguerra, Munazza Qayyum, Lena Eliasson, Claudia Kemper, et al.
  (2012) Immunobiology, 217 p.1148-1149
- MicroRNA differences in human islets and glucose-sensitive tissues
  Caroline Bolmeson, Jonathan Esguerra, Dina Speidel, Lena Eliasson, Corrado Cilio
  (2010) Diabetologia, 53 p.527-527
- Predicted targets of co-expressed microRNAs in pancreatic islets of GK rats are enriched for genes involved in regulation of beta cell mass and glucose-stimulated insulin secretion
  Jonathan Esguerra, Caroline Bolmeson, Corrado Cilio, Lena Eliasson
  (2009) Diabetologia, 52 p.391-391
Journal article
- In Vivo Silencing of MicroRNA-132 Reduces Blood Glucose and Improves Insulin Secretion
  Roel Bijkerk, Jonathan L S Esguerra, Johanne H Ellenbroek, Yu Wah Au, Maaike A J Hanegraaf, et al.
  (2019) Nucleic acid therapeutics, 29 p.67-72
- Defective exocytosis and processing of insulin in a cystic fibrosis mouse model
  Anna Edlund, Mohammad Barghouth, Michael Huhn, Mia Abels, Jonathan Esguerra, et al.
  (2019) Journal of Endocrinology, 241 p.45-57
- miR-483-5p associates with obesity and insulin resistance and independently associates with new onset diabetes mellitus and cardiovascular disease
  Widet Gallo, Jonathan Lou S. Esguerra, Lena Eliasson, Olle Melander
  (2018) PLoS ONE, 13
- MiR-335 overexpression impairs insulin secretion through defective priming of insulin vesicles
  Vishal A. Salunkhe, Jones K. Ofori, Nikhil R. Gandasi, Sofia A. Salö, Sofia Hansson, et al.
  (2017) Physiological Reports, 5
- Identification of islet-enriched long non-coding RNAs contributing to β-cell failure in type 2 diabetes
  Anna Motterle, Sonia Gattesco, Marie Line Peyot, Jonathan Lou S. Esguerra, Ana Ruiz-Gomez, et al.
  (2017) Molecular Metabolism, 6 p.1407-1418
- Confluence does not affect the expression of miR-375 and its direct targets in rat and human insulin-secreting cell lines
  Jones K Ofori, Helena A Malm, Ines G Mollet, Lena Eliasson, Jonathan Lou S Esguerra
  (2017) PeerJ, 5
- Elevated miR-130a/miR130b/miR-152 expression reduces intracellular ATP levels in the pancreatic beta cell
  Jones K. Ofori, Vishal A. Salunkhe, Annika Bagge, Neelanjan Vishnu, Mototsugu Nagao, et al.
  (2017) Scientific Reports, 7
- Endogenous beta-cell CART regulates insulin secretion and transcription of beta-cell genes
  L Shcherbina, A Edlund, J L S Esguerra, M Abels, Y Zhou, et al.
  (2017) Molecular and Cellular Endocrinology, 447 p.52-60
- Neuron-enriched RNA-binding Proteins Regulate Pancreatic Beta Cell Function and Survival
  Jon Agraves Juan-Mateu, Tatiana H Rech, Olatz Villate, Esther Lizarraga-Mollinedo, Anna Wendt, et al.
  (2017) Journal of Biological Chemistry, 292 p.3466-3480
- Whole-genome Bisulfite Sequencing of Human Pancreatic Islets Reveals Novel Differentially Methylated Regions in Type 2 Diabetes Pathogenesis
  Petr Volkov, Karl Bacos, Jones K Ofori, Jonathan Lou S Esguerra, Lena Eliasson, et al.
  (2017) Diabetes, 66 p.1074-1085
- Dual Effect of Rosuvastatin on Glucose Homeostasis Through Improved Insulin Sensitivity and Reduced Insulin Secretion
  Vishal A. Salunkhe, Ines Mollet, Jones K. Ofori, Helena A. Malm, Jonathan L S Esguerra, et al.
  (2016) EBioMedicine, 10 p.185-194
- Transcriptional regulation of the miR-212/miR-132 cluster in insulin-secreting β-cells by cAMP-regulated transcriptional co-activator 1 and salt-inducible kinases.
  Helena Malm, Ines Mollet, Christine Berggreen, Marju Orho-Melander, Jonathan Esguerra, et al.
  (2016) Molecular and Cellular Endocrinology, 424 p.23-33
- CD46 Activation Regulates miR-150-Mediated Control of GLUT1 Expression and Cytokine Secretion in Human CD4+ T Cells.
  Ben King, Jonathan Esguerra, Ewelina Golec, Lena Eliasson, Claudia Kemper, et al.
  (2016) Journal of immunology (Baltimore, Md. : 1950), 196 p.1636-1645
- Modulation of microRNA-375 expression alters voltage-gated Na(+) channel properties and exocytosis in insulin-secreting cells.
  Vishal Ashok Salunkhe, Jonathan Esguerra, Jones Ofori, Ines Mollet, Matthias Braun, et al.
  (2015) Acta Physiologica, 213 p.882-892
- Sex differences in the genome-wide DNA methylation pattern and impact on gene expression, microRNA levels and insulin secretion in human pancreatic islets
  Elin Hall, Petr Volkov, Tasnim Dayeh, Jonathan Esguerra, Sofia Salo, et al.
  (2014) GenomeBiology, 15
- CFTR and Anoctamin 1 (ANO1) contribute to cAMP amplified exocytosis and insulin secretion in human and murine pancreatic beta-cells.
  Anna Edlund, Jonathan Esguerra, Anna Wendt, Malin Flodström-Tullberg, Lena Eliasson
  (2014) BMC Medicine, 12
- Argonaute2 Mediates Compensatory Expansion of the Pancreatic β Cell.
  Sudhir G Tattikota, Thomas Rathjen, Sarah J McAnulty, Hans-Hermann Wessels, Ildem Akerman, et al.
  (2014) Cell Metabolism, 19 p.122-134
- Nova1 is a master regulator of alternative splicing in pancreatic beta cells.
  Olatz Villate, Jean-Valery Turatsinze, Loriana G Mascali, Fabio A Grieco, Tatiane C Nogueira, et al.
  (2014) Nucleic Acids Research, 42 p.11818-11830
- MicroRNA-7a regulates pancreatic beta cell function
  Mathieu Latreille, Jean Hausser, Ina Stuetzer, Quan Zhang, Benoit Hastoy, et al.
  (2014) Journal of Clinical Investigation, 124 p.2722-2735
- Global genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolism.
  Joao Fadista, Petter Vikman, Emilia Ottosson Laakso, Ines Mollet, Jonathan Esguerra, et al.
  (2014) Proceedings of the National Academy of Sciences, 111 p.13924-13929
- A systems genetics approach identifies genes and pathways for type 2 diabetes in human islets.
  Jalal Taneera, Stefan Lang, Amitabh Sharma, Joao Fadista, Yuedan Zhou, et al.
  (2012) Cell Metabolism, 16 p.122-134
- Secreted frizzled-related protein 4 reduces insulin secretion and is overexpressed in type 2 diabetes.
  Taman Mahdi, Sonja Hänzelmann, S Albert Salehi, Sarheed Jabar Muhammed, Thomas Reinbothe, et al.
  (2012) Cell Metabolism, 16 p.625-633
- Beta-cell specific deletion of dicer1 leads to defective insulin secretion and diabetes mellitus.
  Martins Kalis, Caroline Bolmeson, Jonathan Esguerra, Shashank Gupta, Anna Edlund, et al.
  (2011) PLoS ONE, 6
- Differential Glucose-Regulation of MicroRNAs in Pancreatic Islets of Non-Obese Type 2 Diabetes Model Goto-Kakizaki Rat.
  Jonathan Esguerra, Caroline Bolmeson, Corrado Cilio, Lena Eliasson
  (2011) PLoS ONE, 6
- Differences in islet-enriched miRNAs in healthy and glucose intolerant human subjects.
  Caroline Bolmeson, Jonathan Esguerra, S Albert Salehi, Dina Speidel, Lena Eliasson, et al.
  (2011) Biochemical and Biophysical Research Communications, Dec p.16-22
- Functional importance of individual rRNA 2'-O-ribose methylations revealed by high-resolution phenotyping
  Jonathan Esguerra, J. Warringer, A. Blomberg
  (2008) RNA, 14 p.56-649
Journal article review
- Islet microRNAs in health and type-2 diabetes
  Anna Wendt, Jonathan LS Esguerra, Lena Eliasson
  (2018) Current Opinion in Pharmacology, 43 p.46-52
- MicroRNAs in islet hormone secretion
  Jonathan L.S. Esguerra, Mototsugu Nagao, Jones K. Ofori, Anna Wendt, Lena Eliasson
  (2018) Diabetes, Obesity and Metabolism, 20 p.11-19
- Lessons from basic pancreatic beta cell research in type-2 diabetes and vascular complications
  Lena Eliasson, Jonathan Lou S. Esguerra, Anna Wendt
  (2017) Diabetology International, 8 p.139-152
- Regulation of Pancreatic Beta Cell Stimulus-Secretion Coupling by microRNAs.
  Jonathan Esguerra, Ines Mollet, Vishal Ashok Salunkhe, Anna Wendt, Lena Eliasson
  (2014) Genes, 5 p.1018-1031
- Role of non-coding RNAs in pancreatic beta-cell development and physiology.
  Lena Eliasson, Jonathan Esguerra
  (2014) Acta Physiologica, 211 p.273-284
- Functional implications of long non-coding RNAs in the pancreatic islets of Langerhans.
  Jonathan Esguerra, Lena Eliasson
  (2014) Frontiers in Genetics, 5 p.1-9

18 November 2019

Jonathan Esguerra

E-mail: jonathan [dot] esguerra [at] med [dot] lu [dot] se

Assistant researcher

Diabetes - Islet Cell Exocytosis

Telephone number:+46 40 39 11 59

Mobile number:+46 76 836 53 81

Room number:CRC 91-11-014A

Service point:33

Assistant researcher

EXODIAB: Excellence in Diabetes Research in Sweden

My profile in Lund University research portal

Lund University Diabetes Centre

Excellence of diabetes research in Sweden

Jonathan Esguerra, Head, Bioinformatics and management

Publications

Publications

Publications