Jiangming Sun
Bioinformatician
I am intererested in any research topics on precision medicine. In addition to routine bioinformatic analysis, my current job is making our multi-omics data AI ready for the discovery of disease biomarkers and novel therapeutic targets. I am also conducting GWAS studies using our cohort and public summary statistics, e.g. UKB and FinnGen, to group high-risk individuals by means like polygenic risk scores and to estimate causality by Mendelian randomization. Moreover, we will explore chamical space for potential drugs.
Publications
Displaying of publications. Sorted by year, then title.
Genetic Susceptibility to Mood Disorders and Risk of Stroke : A Polygenic Risk Score and Mendelian Randomization Study
Jiangming Sun, Yan Borné, Andreas Edsfeldt, Yunpeng Wang, Mengyu Pan, et al.
(2023) Stroke
Journal articlePolygenic scores for low lung function and the future risk of adverse health outcomes
Suneela Zaigham, Isabel Gonçalves, Gunnar Engström, Jiangming Sun
(2022) Cardiovascular Diabetology, 21 p.1-10
Journal articleIncreased proteolytic cleavage of osteoglycin is associated with a stable plaque phenotype and lower risk of cardiovascular events
Dania Al-Sharify, Signe Holm Nielsen, Frank Matthes, Christoffer Tengryd, Jiangming Sun, et al.
(2022) Atherosclerosis, 355 p.8-14
Journal articleOsteomodulin Gene Expression Is Associated with Plaque Calcification, Stability, and Fewer Cardiovascular Events in the CPIP Cohort
Isabel Gonçalves, Loureen Oduor, Frank Matthes, Narjess Rakem, Jakob Meryn, et al.
(2022) Stroke, 53 p.79-84
Journal articleInterferon regulatory factor-5-dependent CD11c+ macrophages contribute to the formation of rupture-prone atherosclerotic plaques
Andreas Edsfeldt, Maarten Swart, Pratibha Singh, Lea Dib, Jiangming Sun, et al.
(2022) European Heart Journal, 43 p.1864-1877
Journal articleEpigenome-Wide Histone Acetylation Changes in Peripheral Blood Mononuclear Cells in Patients with Type 2 Diabetes and Atherosclerotic Disease
Pradeep Bompada, Isabel Goncalves, Chuanyan Wu, Rui Gao, Jiangming Sun, et al.
(2021) Biomedicines, 9
Journal articleTranslating polygenic risk scores for clinical use by estimating the confidence bounds of risk prediction
Jiangming Sun, Yunpeng Wang, Lasse Folkersen, Yan Borné, Inge Amlien, et al.
(2021) Nature Communications, 12 p.5276-5276
Journal articlePlaque vulnerability index predicts cardiovascular events : A histological study of an endarterectomy cohort
Isabel Goncalves, Jiangming Sun, Christoffer Tengryd, Mihaela Nitulescu, Ana F. Persson, et al.
(2021) Journal of the American Heart Association, 10
Journal articleSerum Renin Levels Increase With Age in Boys Resulting in Higher Renin Levels in Young Men Compared to Young Women, and Soluble Angiotensin-Converting Enzyme 2 Correlates With Renin and Body Mass Index
Lars Jehpsson, Jiangming Sun, Peter M. Nilsson, Andreas Edsfeldt, Per Swärd
(2021) Frontiers in Physiology, 11
Journal articleHuman Atherosclerotic Plaque Progression Is Dependent on Apoptosis According to Bomb-Pulse 14C Dating
Andreas Edsfeldt, Kristina Eriksson Stenström, Jiangming Sun, Nuno Dias, Göran Skog, et al.
(2021) JACC: Basic to Translational Science, 6 p.734-745
Journal articleHyperglycaemia-associated Caspase-3 predicts diabetes and coronary artery disease events
Jiangming Sun, Pratibha Singh, Johan Österlund, Marju Orho-Melander, Olle Melander, et al.
(2021) Journal of Internal Medicine, 290 p.855-865
Journal articleGenome-wide association study identifies 16 genomic regions associated with circulating cytokines at birth
Yunpeng Wang, Ron Nudel, Michael E. Benros, Kristin Skogstrand, Simon Fishilevich, et al.
(2020) PLoS Genetics, 16
Journal articleAssociation of TIM-1 (T-Cell Immunoglobulin and Mucin Domain 1) With Incidence of Stroke
Lu Song, Jiangming Sun, Martin Söderholm, Olle Melander, Marju Orho-Melander, et al.
(2020) Arteriosclerosis, Thrombosis, and Vascular Biology, 40 p.1777-1786
Journal articleRegulation of Nuclear Receptor Interacting Protein 1 (NRIP1) Gene Expression in Response to Weight Loss and Exercise in Humans
Yang De Marinis, Jiangming Sun, Pradeep Bompada, Judit Domènech Omella, Cheng Luan, et al.
(2017) Obesity, 25 p.1400-1409
Journal articleGlycogen metabolism in the glucose-sensing and supply-driven β-cell
Lotta E. Andersson, Lisa M. Nicholas, Karin Filipsson, Jiangming Sun, Anya Medina Benavente, et al.
(2016) FEBS Letters, 590 p.4242-4251
Journal article (letter)Discriminative prediction of A-To-I RNA editing events from DNA sequence
Jiangming Sun, Yang De Marinis, Peter Osmark, Pratibha Singh, Annika Bagge, et al.
(2016) PLoS ONE, 11
Journal articleLoss of TFB1M results in mitochondrial dysfunction that leads to impaired insulin secretion and diabetes.
Vladimir Sharoyko, Mia Abels, Jiangming Sun, Lisa Nicholas, Ines Mollet, et al.
(2014) Human Molecular Genetics, 23 p.5733-5749
Journal articleGlucagon-Like Peptide 1 Stimulates Insulin Secretion via Inhibiting RhoA/ROCK Signaling and Disassembling Glucotoxicity-Induced Stress Fibers
Xiangchen Kong, Dan Yan, Jiangming Sun, Xuerui Wu, Hindrik Mulder, et al.
(2014) Endocrinology, 155 p.4676-4685
Journal articlePlantLoc: an accurate web server for predicting plant protein subcellular localization by substantiality motif.
Shengnan Tang, Tonghua Li, Peisheng Cong, Wenwei Xiong, Zhiheng Wang, et al.
(2013) Nucleic Acids Research, 41 p.441-447
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