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Jens Lagerstedt

Associate professor

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Regulation of phosphate acquisition in Saccharomyces cerevisiae

Author

  • Bengt L Persson
  • Jens O Lagerstedt
  • James R Pratt
  • Johanna Pattison-Granberg
  • Kent I Lundh
  • Soheila Shokrollahzadeh
  • Fredrik Lundh

Summary, in English

Membrane transport systems active in cellular inorganic phosphate (P(i)) acquisition play a key role in maintaining cellular P(i) homeostasis, independent of whether the cell is a unicellular microorganism or is contained in the tissue of a higher eukaryotic organism. Since unicellular eukaryotes such as yeast interact directly with the nutritious environment, regulation of P(i) transport is maintained solely by transduction of nutrient signals across the plasma membrane. The individual yeast cell thus recognizes nutrients that can act as both signals and sustenance. The present review provides an overview of P(i) acquisition via the plasma membrane P(i) transporters of Saccharomyces cerevisiae and the regulation of internal P(i) stores under the prevailing P(i) status.

Publishing year

2003-07

Language

English

Pages

44-225

Publication/Series

Current Genetics

Volume

43

Issue

4

Document type

Journal article

Publisher

Springer

Keywords

  • Algorithms
  • Amino Acid Sequence
  • Cell Membrane
  • Gene Expression Regulation, Fungal
  • Magnetic Resonance Spectroscopy
  • Models, Biological
  • Molecular Sequence Data
  • Phosphates
  • Polyphosphates
  • Protein Structure, Secondary
  • Proton-Phosphate Symporters
  • Saccharomyces cerevisiae
  • Saccharomyces cerevisiae Proteins
  • Journal Article
  • Research Support, Non-U.S. Gov't
  • Review

Status

Published

ISBN/ISSN/Other

  • ISSN: 0172-8083