Jens Lagerstedt
Associate professor
Publications
Displaying of publications. Sorted by year, then title.
Secretory granule exocytosis and its amplification by cAMP in pancreatic β-cells
Mototsugu Nagao, Jens O. Lagerstedt, Lena Eliasson
(2022) Diabetology International
Journal article reviewStructure dynamics of ApoA-I amyloidogenic variants in small HDL increase their ability to mediate cholesterol efflux
Oktawia Nilsson, Mikaela Lindvall, Laura Obici, Simon Ekström, Jens O. Lagerstedt, et al.
(2021) Journal of Lipid Research, 62
Journal articleApoA-1 improves glucose tolerance by increasing glucose uptake into heart and skeletal muscle independently of AMPKα2
Andreas Mæchel Fritzen, Joan Domingo-Espín, Anne Marie Lundsgaard, Maximilian Kleinert, Ida Israelsen, et al.
(2020) Molecular Metabolism, 35
Journal articleApolipoprotein A-I primes beta cells to increase glucose stimulated insulin secretion
Oktawia Nilsson, Rita Del Giudice, Mototsugu Nagao, Caitriona Grönberg, Lena Eliasson, et al.
(2020) Biochimica et Biophysica Acta - Molecular Basis of Disease, 1866
Journal articleA short peptide of the C-terminal class Y helices of apolipoprotein A-I has preserved functions in cholesterol efflux and in vivo metabolic control
Shelley J. Edmunds, Rebeca Liébana-García, Karin G. Stenkula, Jens O. Lagerstedt
(2020) Scientific Reports, 10
Journal articleLoss of ZnT8 function protects against diabetes by enhanced insulin secretion
Om Prakash Dwivedi, Mikko Lehtovirta, Benoit Hastoy, Vikash Chandra, Nicole A. J. Krentz, et al.
(2019) Nature Genetics , p.1-22
Journal articleApoAI-derived peptide increases glucose tolerance and prevents formation of atherosclerosis in mice
Shelley J Edmunds, Rebeca Liébana-García, Oktawia Nilsson, Joan Domingo-Espín, Caitriona Grönberg, et al.
(2019) Diabetologia, 62 p.1257-1267
Journal articleNovel ABCA1 peptide agonists with antidiabetic action
Salman Azhar, Stefanie Bittner, Jie Hu, Wen Jun Shen, Yuan Cortez, et al.
(2019) Molecular and Cellular Endocrinology, 480 p.1-11
Journal articleAnti-ApoA-I IgG antibodies are not associated with carotid artery disease progression and first-time cardiovascular events in middle-aged individuals
J. O. Lagerstedt, J. Dalla-Riva, G. Marinkovic, R. Del Giudice, D. Engelbertsen, et al.
(2019) Journal of Internal Medicine, 285 p.49-58
Journal articleSite-specific glycations of apolipoprotein A-I lead to differentiated functional effects on lipid-binding and on glucose metabolism
Joan Domingo-Espín, Oktawia Nilsson, Katja Bernfur, Rita Del Giudice, Jens O. Lagerstedt
(2018) Biochimica et Biophysica Acta - Molecular Basis of Disease, 1864 p.2822-2834
Journal articleHigh-efficient bacterial production of human ApoA-I amyloidogenic variants
Rita Del Giudice, Jens O. Lagerstedt
(2018) Protein Science, 27 p.2101-2109
Journal articleSynchrotron radiation circular dichroism spectroscopy reveals structural divergences in HDL-bound apoA-I variants
Rita Del Giudice, Oktawia Nilsson, Joan Domingo-Espín, Jens O Lagerstedt
(2017) Scientific Reports, 7
Journal articleApolipoprotein A-I attenuates LL-37-induced endothelial cell cytotoxicity
Daniel Svensson, Jens O. Lagerstedt, Bengt Olof Nilsson, Rita Del Giudice
(2017) Biochemical and Biophysical Research Communications, 493 p.71-76
Journal articlePlasma stem cell factor levels are associated with risk of cardiovascular disease and death
H Björkbacka, I Yao Mattisson, M Wigren, O Melander, G. N. Fredrikson, et al.
(2017) Journal of Internal Medicine, 282 p.508-521
Journal articleStructures of apolipoprotein A-I in high density lipoprotein generated by electron microscopy and biased simulations
Lin Zhu, Jitka Petrlova, Peter Gysbers, Hans Hebert, Stefan Wallin, et al.
(2017) Biochimica et Biophysica Acta - General Subjects, 1861 p.2726-2738
Journal articleStructural determinants in ApoA-I amyloidogenic variants explain improved cholesterol metabolism despite low HDL levels
Rita Del Giudice, Joan Domingo-Espín, Ilaria Iacobucci, Oktawia Nilsson, Maria Cristina Monti, et al.
(2017) Biochimica et Biophysica Acta, 1863 p.3038-3048
Journal articleMolecular crowding impacts the structure of apolipoprotein A-I with potential implications on in vivo metabolism and function
Jitka Petrlova, Silvia Hilt, Madhu Budamagunta, Joan Domingo-Espín, John C. Voss, et al.
(2016) Biopolymers, 105 p.683-692
Journal articleDual actions of apolipoprotein A-I on glucose-stimulated insulin secretion and insulin-independent peripheral tissue glucose uptake lead to increased heart and skeletal muscle glucose disposal
Joan Domingo-Espín, Maria Lindahl, Oktawia Nilsson, Samuel W Cushman, Karin G. Stenkula, et al.
(2016) Diabetes, 65 p.1838-1848
Journal articleStructural and Functional Analysis of the ApolipoproteinA-I A164S Variant.
Jonathan Dalla-Riva, Jens Lagerstedt, Jitka Petrlova
(2015) PLoS ONE, 10
Journal articleZnT8 autoantibody epitope specificity and affinity examined with recombinant ZnT8 variant proteins in specific ZnT8R and ZnT8W autoantibody positive type 1 diabetes patients.
Hanna Skärstrand, Ewa Krupinska, Tatu Haataja, Fariba Vaziri Sani, Jens Lagerstedt, et al.
(2015) Clinical and Experimental Immunology, 179 p.220-229
Journal articleApoA-I Milano stimulates lipolysis in adipose cells independently of cAMP/PKA activation.
Maria Lindahl, Jitka Petrlova, Jonathan Dalla-Riva, Sebastian Wasserstrom, Catarina Rippe, et al.
(2015) Journal of Lipid Research, 56 p.2248-2259
Journal articleConformational and aggregation properties of the 1-93 fragment of apolipoprotein A-I
Jitka Petrlova, Arnab Bhattacherjee, Wouter Boomsma, Stefan Wallin, Jens O Lagerstedt, et al.
(2014) Protein Science, 23 p.71-1559
Journal articleSecondary Structure Changes in ApoA-I Milano (R173C) Are Not Accompanied by a Decrease in Protein Stability or Solubility.
Jitka Petrlova, Jonathan Dalla-Riva, Matthias Mörgelin, Maria Lindahl, Ewa Krupinska, et al.
(2014) PLoS ONE, 9
Journal articleSuperantigen activates the gp130 receptor on adipocytes resulting in altered adipocyte metabolism.
Elin Banke, Karin Rödström, Mikael Ekelund, Jonathan Dalla-Riva, Jens Lagerstedt, et al.
(2014) Metabolism, Clinical and Experimental, 63 p.831-840
Journal articleConformational and aggregation properties of the 1-93 fragment of apolipoprotein A-I.
Jitka Petrlova, Arnab Bhattacherjee, Wouter Boomsma, Stefan Wallin, Jens Lagerstedt, et al.
(2014) Protein Science, 23 p.1559-1571
Journal articleSingle injections of apoA-I acutely improve in vivo glucose tolerance in insulin-resistant mice.
Karin Stenkula, Maria Lindahl, Jitka Petrlova, Jonathan Dalla-Riva, Olga Göransson, et al.
(2014) Diabetologia, 57 p.797-800
Journal articleCharacterization of the biochemical and biophysical properties of the Saccharomyces cerevisiae phosphate transporter Pho89
Palanivelu Sengottaiyan, Jitka Petrlova, Jens O Lagerstedt, Lorena Ruiz-Pavon, Madhu S. Budamagunta, et al.
(2013) Biochemical and Biophysical Research Communications, 436 p.551-556
Journal articleThe secondary structure of apolipoprotein A-I on 9.6-nm reconstituted high-density lipoprotein determined by EPR spectroscopy
Michael N. Oda, Madhu S. Budamagunta, Mark S. Borja, Jitka Petrlova, John C. Voss, et al.
(2013) The FEBS Journal, 280 p.3416-3424
Journal articleEPR assessment of protein sites for incorporation of Gd(III) MRI contrast labels.
Jens Lagerstedt, Jitka Petrlova, Silvia Hilt, Antonin Marek, Youngran Chung, et al.
(2013) Contrast Media & Molecular Imaging, 8 p.252-264
Journal articleDiscoidal HDL and apoA-I-derived peptides improve glucose uptake in skeletal muscle.
Jonathan Dalla-Riva, Karin Stenkula, Jitka Petrlova, Jens Lagerstedt
(2013) Journal of Lipid Research, 54 p.1275-1282
Journal articleDouble Electron-Electron Resonance Probes Ca2+-Induced Conformational Changes and Dimerization of Recoverin
William K. Myers, Xianzhong Xu, Congmin Li, Jens Lagerstedt, Madhu S. Budamagunta, et al.
(2013) Biochemistry, 52 p.5800-5808
Journal articleThe intrinsic GTPase activity of the Gtr1 protein from Saccharomyces cerevisiae
Palanivelu Sengottaiyan, Cornelia Spetea, Jens Lagerstedt, Dieter Samyn, Michael Andersson, et al.
(2012) BMC Biochemistry, 13
Journal articleThe fibrillogenic L178H variant of apolipoprotein A-I forms helical fibrils.
Jitka Petrlova, Trang Duong, Megan C Cochran, Annika Axelsson, Matthias Mörgelin, et al.
(2012) Journal of Lipid Research, 53 p.390-398
Journal articleThe "beta-clasp" model of apolipoprotein A-I - A lipid-free solution structure determined by electron paramagnetic resonance spectroscopy.
Jens Lagerstedt, Madhu S Budamagunta, Grace S Liu, Nicole C Devalle, John Voss, et al.
(2012) Biochimica et biophysica acta, 1821 p.448-455
Journal articlePostprandial apoE Isoform and Conformational Changes Associated with VLDL Lipolysis Products Modulate Monocyte Inflammation
Laura J. den Hartigh, Robin Altman, Romobia Hutchinson, Jitka Petrlova, Madhu S. Budamagunta, et al.
(2012) PLoS ONE, 7
Journal articleStructural Modeling and Electron Paramagnetic Resonance Spectroscopy of the Human Na+/H+ Exchanger Isoform 1, NHE1
Eva B. Nygaard, Jens Lagerstedt, Gabriel Bjerre, Biao Shi, Madhu Budamagunta, et al.
(2011) Journal of Biological Chemistry, 286 p.634-648
Journal articleImaging apolipoprotein AI in vivo
Renuka Sriram, Jens Lagerstedt, Jitka Petrlova, Haris Samardzic, Ulrike Kreutzer, et al.
(2011) NMR in Biomedicine, 24 p.916-924
Journal articleStructure of apolipoprotein A-I's N-terminus on nascent high density lipoprotein.
Jens Lagerstedt, Giorgio Cavigiolio, Madhu S Budamagunta, Ioanna Pagani, John C Voss, et al.
(2011) Journal of Biological Chemistry, 286 p.2966-2975
Journal articleStructural properties of amyloidogenic apoA-I mutant L178H
A Axelsson, M. Cochran, T. Duong, M. Chokshi, J. C. Voss, et al.
(2010) The FEBS Journal, 277 p.72-72
Conference paper: abstractEPR evaluation of proteins engineered to carry Gd(III) contrast labels
J. Petrlova, Jens Lagerstedt, R. Sriram, J. Desreux, D. Thonon, et al.
(2010) The FEBS Journal, 277 p.68-68
Conference paper: abstractMolecular mechanisms controlling phosphate-induced downregulation of the yeast Pho84 phosphate transporter
Fredrik Lundh, Jean-Marie Mouillon, Dieter Samyn, Kent Stadler, Yulia Popova, et al.
(2009) Biochemistry, 48 p.505-4497
Journal articleBridging across length scales : multi-scale ordering of supported lipid bilayers via lipoprotein self-assembly and surface patterning
Madhuri S Vinchurkar, Daniel A Bricarello, Jens O Lagerstedt, James P Buban, Henning Stahlberg, et al.
(2008) Journal of the American Chemical Society, 130 p.9-11164
Journal articleMapping the structural transition in an amyloidogenic apolipoprotein A-I
Jens O Lagerstedt, Giorgio Cavigiolio, Linda M Roberts, Hyun-Seok Hong, Lee-Way Jin, et al.
(2007) Biochemistry, 46 p.9-9693
Journal articleIdentification, expression, and functional analyses of a thylakoid ATP/ADP carrier from Arabidopsis
Sophie Thuswaldner, Jens O Lagerstedt, Marc Rojas-Stütz, Karim Bouhidel, Christophe Declercq, et al.
(2007) Journal of Biological Chemistry, 282 p.59-8848
Journal articleElectron paramagnetic resonance spectroscopy of site-directed spin labels reveals the structural heterogeneity in the N-terminal domain of apoA-I in solution
Jens O Lagerstedt, Madhu S. Budamagunta, Michael N. Oda, John C Voss
(2007) Journal of Biological Chemistry, 282 p.9-9143
Journal articleStructure and function of the GTP binding protein Gtr1 and its role in phosphate transport in Saccharomyces cerevisiae
Jens O Lagerstedt, Ian Reeve, John C Voss, Bengt L Persson
(2005) Biochemistry, 44 p.7-511
Journal articleStructural modeling of dual-affinity purified Pho84 phosphate transporter
Jens O Lagerstedt, John C Voss, Ake Wieslander, Bengt L Persson
(2004) FEBS Letters, 578 p.8-262
Journal articleEffects of methylphosphonate, a phosphate analogue, on the expression and degradation of the high-affinity phosphate transporter Pho84, in Saccharomyces cerevisiae
James R Pratt, Jean-Marie Mouillon, Jens O Lagerstedt, Johanna Pattison-Granberg, Kent I Lundh, et al.
(2004) Biochemistry, 43 p.53-14444
Journal articleRegulation of phosphate acquisition in Saccharomyces cerevisiae
Bengt L Persson, Jens O Lagerstedt, James R Pratt, Johanna Pattison-Granberg, Kent I Lundh, et al.
(2003) Current Genetics, 43 p.44-225
Journal articleMutagenic and functional analysis of the C-terminus of Saccharomyces cerevisiae Pho84 phosphate transporter
Jens O. Lagerstedt, Renata Zvyagilskaya, James R Pratt, Johanna Pattison-Granberg, Arthur L Kruckeberg, et al.
(2002) FEBS Letters, 526 p.7-31
Journal articleProperties of the cysteine-less Pho84 phosphate transporter of Saccharomyces cerevisiae
A Berhe, Renata Zvyagilskaya, J O Lagerstedt, James R Pratt
(2001) Biochemical and Biophysical Research Communications, 287 p.42-837
Journal articlePhosphate permeases of Saccharomyces cerevisiae : Structure, function and regulation
Bengt L. Persson, Jens Lagerstedt, Ulrika Fristedt, Rolf Weinander, Abraham Berhe, et al.
(1999) Biochimica et Biophysica Acta - Reviews on Biomembranes, 1422 p.255-272
Journal article reviewIntracellular localization of an active green fluorescent protein-tagged Pho84 phosphate permease in Saccharomyces cerevisiae
Jens Petersson, Johanna Pattison, Arthur L Kruckeberg, Jan A Berden, B L Persson
(1999) FEBS Letters, 462 p.37-42
Journal articlePhosphate permeases of Saccharomyces cerevisiae
Persson B. L., A. Berhe, U. Fristedt, P. Martinez, J. Pattison, et al.
(1998) Biochimica et Biophysica Acta - Bioenergetics, 1365 p.23-30
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