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Low elastin content of carotid plaques is associated with increased risk of ipsilateral stroke.

  • Giuseppe Asciutto
  • Nuno Dias
  • Andreas Edsfeldt
  • Mihaela Nitulescu
  • Ana Persson
  • Marie MN Nilsson
  • Pontus Dunér
  • Jan Nilsson
  • Isabel Goncalves
Publishing year: 2015
Language: English
Publication/Series: PLoS ONE
Volume: 10
Issue: 3
Document type: Journal article
Publisher: Public Library of Science

Abstract english

Atherosclerotic plaques with a low content of connective tissue proteins are believed to have an increased risk of rupture and to give rise to clinical events. The aim of the present study was to investigate if the content of elastin, collagen and of the matrix metalloproteinase (MMP) -1, -3, -9 and -12 in plaques removed at surgery can be associated with the occurrence of ipsilateral symptoms.


  • Cardiac and Cardiovascular Systems


  • Cardiovascular Research - Immunity and Atherosclerosis
  • Vascular Diseases - Clinical Research
  • ISSN: 1932-6203
E-mail: jan [dot] nilsson [at] med [dot] lu [dot] se

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