Plasma autoantibodies against apolipoprotein B-100 peptide 210 in subclinical atherosclerosis.
- Cardiovascular Research - Immunity and Atherosclerosis
- EXODIAB: Excellence in Diabetes Research in Sweden
- EpiHealth: Epidemiology for Health
Publishing year: 2014
Document type: Journal article
Experimental studies have suggested that autoimmunity is involved in atherosclerosis and provided evidence that both protective and pro-atherogenic immune responses exist. This concept has received support from small clinical studies implicating autoantibodies directed against apolipoprotein B-100 (apoB-100) in human atherosclerosis. We examined circulating autoantibodies directed against native and malondialdehyde (MDA)-modified epitope p210 of apoB-100 (IgG-p210nat and IgM-p210MDA) in relation to early atherosclerosis in a large, European longitudinal cohort study of healthy high-risk individuals.
- Cardiac and Cardiovascular Systems
- Cardiovascular Research - Immunity and Athersosclerosis
- ISSN: 1879-1484
E-mail: jan [dot] nilsson [at] med [dot] lu [dot] se