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Jan Nilsson

Professor

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CD8+ T cell activation predominate early immune responses to hypercholesterolemia in Apoe-/- mice.

Author

  • Daniel Kolbus
  • Ornélia Ramos
  • Katarina Berg
  • Josefin Persson
  • Maria Wigren
  • Harry Björkbacka
  • Gunilla Nordin Fredrikson
  • Jan Nilsson

Summary, in English

It is well established that adaptive immune responses induced by hypercholesterolemia play an important role in the development of atherosclerosis, but the pathways involved remain to be fully characterized. In the present study we assessed immune responses to hypercholesterolemia induced by feeding Apoe-/- mice a high-fat diet for 4 or 8 weeks.

Department/s

  • Cardiovascular Research - Immunity and Atherosclerosis
  • EXODIAB: Excellence in Diabetes Research in Sweden
  • EpiHealth: Epidemiology for Health

Publishing year

2010

Language

English

Publication/Series

BMC Immunology

Volume

11

Document type

Journal article

Publisher

BioMed Central (BMC)

Topic

  • Immunology in the medical area

Status

Published

Research group

  • Cardiovascular Research - Immunity and Atherosclerosis

ISBN/ISSN/Other

  • ISSN: 1471-2172