Javascript is not activated in your browser. This website needs javascript activated to work properly.
You are here

CD8+ T cell activation predominate early immune responses to hypercholesterolemia in Apoe-/- mice.

  • Daniel Kolbus
  • Ornélia Ramos
  • Katarina Berg
  • Josefin Persson
  • Maria Wigren
  • Harry Björkbacka
  • Gunilla Nordin Fredrikson
  • Jan Nilsson
Publishing year: 2010
Language: English
Publication/Series: BMC Immunology
Volume: 11
Document type: Journal article
Publisher: BioMed Central (BMC)

Abstract english

It is well established that adaptive immune responses induced by hypercholesterolemia play an important role in the development of atherosclerosis, but the pathways involved remain to be fully characterized. In the present study we assessed immune responses to hypercholesterolemia induced by feeding Apoe-/- mice a high-fat diet for 4 or 8 weeks.


  • Immunology in the medical area


  • Cardiovascular Research - Immunity and Atherosclerosis
  • ISSN: 1471-2172
E-mail: jan [dot] nilsson [at] med [dot] lu [dot] se

Lund University Diabetes Centre, CRC, SUS Malmö, Jan Waldenströms gata 35, House 91:12. SE-214 28 Malmö. Telephone: +46 40 39 10 00