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Jan Nilsson

Professor

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Potential Influence of Diet on Bomb-Pulse Dating of Human Plaque Samples

Author

  • Elisavet Georgiadou
  • Isabel Goncalves
  • Cintia Bertacchi Uvo
  • Jan Nilsson
  • Göran Skog
  • Sören Mattsson
  • Luis M. Pedro
  • Jose Fernandes e Fernandes
  • Kristina Stenström

Summary, in English

The radiocarbon concentration of different atherosclerotic plaque fragments obtained from 20 patients in Portugal, operated in 2000-2001, has been measured in order to define the year of plaque formation. A difference of 1.8-15 yr was observed, with the mean and median both 9 yr, between the bomb-pulse date estimated with the CALIBomb software and the operation date. Stable isotope (delta C-13 and delta N-15) analysis was also performed and provides insight to the diet of the subjects. The wide range of measured stable isotope values could indicate that the subjects' diet varied, including an abundance of marine foodstuffs. It could also mean a different isotope fractionation process for the different plaque fragments (cap, core, interface to media) and a possible difference in tissues in which the various fragments are formed. Analysis of delta C-13 and delta N-15 values of each patient separately revealed subjects considered more influenced by marine foodstuffs consumption.

Department/s

  • Nuclear physics
  • Cardiovascular Research - Immunity and Atherosclerosis
  • Division of Water Resources Engineering
  • Quaternary Sciences
  • Medical Radiation Physics, Malmö
  • EXODIAB: Excellence in Diabetes Research in Sweden
  • EpiHealth: Epidemiology for Health
  • MERGE - ModElling the Regional and Global Earth system

Publishing year

2013

Language

English

Pages

874-884

Publication/Series

Radiocarbon

Volume

55

Issue

2-3

Document type

Journal article

Publisher

Arizona Board of Regents (University of Arizona)

Topic

  • Cardiac and Cardiovascular Systems
  • Radiology, Nuclear Medicine and Medical Imaging

Keywords

  • bomb-pulse daitng
  • human plaque samples
  • stable isotopes

Conference name

21st International Radiocarbon Conference, 2012

Conference date

0001-01-02

Status

Published

Research group

  • Cardiovascular Research - Immunity and Atherosclerosis
  • Medical Radiation Physics, Malmö

ISBN/ISSN/Other

  • ISSN: 0033-8222