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Circulating cytokines reflect the expression of pro-inflammatory cytokines in atherosclerotic plaques.

  • Andreas Edsfeldt
  • Helena Grufman
  • Giuseppe Asciutto
  • Mihaela Nitulescu
  • Ana Persson
  • Marie MN Nilsson
  • Jan Nilsson
  • Isabel Goncalves
Publishing year: 2015
Language: English
Pages: 443-449
Publication/Series: Atherosclerosis
Volume: 241
Issue: 2
Document type: Journal article
Publisher: Elsevier

Abstract english

Inflammation is a key factor in the development of plaque rupture and acute cardiovascular events. Although imaging techniques can be used to identify vulnerable atherosclerotic plaques, we are lacking non-invasive methods, such as plasma markers of plaque inflammation that could help to identify presence of vulnerable plaques. The aim of the present study was to investigate whether increased plasma levels of pro-inflammatory cytokines reflects inflammatory activity within atherosclerotic plaques.


  • Cardiac and Cardiovascular Systems


  • Cardiovascular Research - Immunity and Athersosclerosis
  • ISSN: 1879-1484
E-mail: jan [dot] nilsson [at] med [dot] lu [dot] se

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