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Evidence for altered inflammatory and repair responses in symptomatic carotid plaques from elderly patients.

  • Helena Grufman
  • Alexandru Schiopu
  • Andreas Edsfeldt
  • Harry Björkbacka
  • Mihaela Nitulescu
  • Marie MN Nilsson
  • Ana Persson
  • Jan Nilsson
  • Isabel Goncalves
Publishing year: 2014
Language: English
Pages: 177-182
Publication/Series: Atherosclerosis
Volume: 237
Issue: 1
Document type: Journal article
Publisher: Elsevier

Abstract english

Most acute cardiovascular events are caused by rupture of an atherosclerotic plaque. The incidence of cardiovascular events increases with age and inflammation is generally considered to be the main cause of increased plaque vulnerability. However, the relationship between age and plaque inflammation has not yet been fully clarified. The aim of our study was to determine if age-dependent plaque vulnerability is associated with increased plaque inflammation.


  • Cardiac and Cardiovascular Systems


  • Cardiovascular Research - Immunity and Atherosclerosis
  • ISSN: 1879-1484
E-mail: jan [dot] nilsson [at] med [dot] lu [dot] se

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