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Impaired Fibrous Repair: A Possible Contributor to Atherosclerotic Plaque Vulnerability in Patients With Type II Diabetes.

  • Andreas Edsfeldt
  • Isabel Goncalves
  • Helena Grufman
  • Mihaela Nitulescu
  • Pontus Dunér
  • Eva Bengtsson
  • Ines Mollet
  • Ana Persson
  • Marie MN Nilsson
  • Marju Orho-Melander
  • Olle Melander
  • Harry Björkbacka
  • Jan Nilsson
Publishing year: 2014
Language: English
Pages: 2143-2150
Publication/Series: Arteriosclerosis, Thrombosis and Vascular Biology
Volume: 34
Issue: 9
Document type: Journal article
Publisher: Lippincott Williams Wilkins Hagerstown, MD

Abstract english

Diabetes mellitus (DM) type II is increasing rapidly worldwide. Patients with DM II have a greater atherosclerotic burden and higher risk of developing cardiovascular complications. Inflammation has been proposed as the main cause for the high risk of atherosclerotic disease in DM II. In this study, we compared markers of inflammation and fibrous repair in plaques from subjects with and without DM II.


  • Cardiac and Cardiovascular Systems


  • Cardiovascular Research - Immunity and Athersosclerosis
  • Diabetes - Islet Cell Exocytosis
  • Diabetes - Cardiovascular Disease
  • Cardiovascular Research - Hypertension
  • ISSN: 1524-4636
E-mail: jan [dot] nilsson [at] med [dot] lu [dot] se

Lund University Diabetes Centre, CRC, SUS Malmö, Jan Waldenströms gata 35, House 91:12. SE-214 28 Malmö. Telephone: +46 40 39 10 00