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Smoking modifies the associated increased risk of future cardiovascular disease by genetic variation on chromosome 9p21.

Author:
  • Viktor Hamrefors
  • Bo Hedblad
  • George Hindy
  • Gustav Smith
  • Peter Almgren
  • Gunnar Engström
  • Marketa Sjögren
  • Klas Gränsbo
  • Marju Orho-Melander
  • Olle Melander
Publishing year: 2014
Language: English
Publication/Series: PLoS ONE
Volume: 9
Issue: 1
Document type: Journal article
Publisher: Public Library of Science

Abstract english

Genetic predisposition for cardiovascular disease (CVD) is likely to be modified by environmental exposures. We tested if the associated risk of CVD and CVD-mortality by the single nucleotide polymorphism rs4977574 on chromosome 9p21 is modified by life-style factors.

Keywords

  • Endocrinology and Diabetes
  • Cardiac and Cardiovascular Systems

Other

Published
  • Hypertension and Cardiovascular Disease
  • Cardio-vascular Epidemiology
  • Diabetes and cardiovascular disease - genetic epidemiolgy
  • Diabetes and Endocrinology
  • ISSN: 1932-6203
E-mail: gustav [dot] smith [at] med [dot] lu [dot] se

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Cardiology

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Cardiovascular Epigenetics

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Heart Failure and Mechanical Support

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Molecular Epidemiology and Cardiology

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