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Isabel Goncalves

Professor

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Low elastin content of carotid plaques is associated with increased risk of ipsilateral stroke.

Author

  • Giuseppe Asciutto
  • Nuno Dias
  • Andreas Edsfeldt
  • Mihaela Nitulescu
  • Ana Persson
  • Marie MN Nilsson
  • Pontus Dunér
  • Jan Nilsson
  • Isabel Goncalves

Summary, in English

Atherosclerotic plaques with a low content of connective tissue proteins are believed to have an increased risk of rupture and to give rise to clinical events. The aim of the present study was to investigate if the content of elastin, collagen and of the matrix metalloproteinase (MMP) -1, -3, -9 and -12 in plaques removed at surgery can be associated with the occurrence of ipsilateral symptoms.

Department/s

  • EXODIAB: Excellence of Diabetes Research in Sweden
  • EpiHealth: Epidemiology for Health
  • Cardiovascular Research - Immunity and Atherosclerosis
  • Vascular Diseases - Clinical Research
  • Cardiovascular Research - Translational Studies

Publishing year

2015

Language

English

Publication/Series

PLoS ONE

Volume

10

Issue

3

Document type

Journal article

Publisher

Public Library of Science (PLoS)

Topic

  • Cardiac and Cardiovascular Systems

Status

Published

Research group

  • Cardiovascular Research - Immunity and Atherosclerosis
  • Vascular Diseases - Clinical Research
  • Cardiovascular Research - Translational Studies

ISBN/ISSN/Other

  • ISSN: 1932-6203