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Isabel Goncalves

Professor

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Low levels of IgG autoantibodies against the apolipoprotein B antigen p210 increases the risk of cardiovascular death after carotid endarterectomy.

Author

  • Giuseppe Asciutto
  • Nuno Dias
  • Andreas Edsfeldt
  • Ragnar Alm
  • Gunilla Nordin Fredrikson
  • Isabel Goncalves
  • Jan Nilsson

Summary, in English

Autoimmune responses against oxidized-LDL (oxLDL) have been suggested to modulate inflammation in atherosclerosis. Previous studies showed an association between autoantibodies against the apolipoprotein B (apoB) p210 antigen and a lower risk of cardiovascular (CV) events. In the present study we investigated if autoantibodies against p210 at the time of carotid endarterectomy (CEA) predict risk for future CV events.

Department/s

  • EXODIAB: Excellence of Diabetes Research in Sweden
  • EpiHealth: Epidemiology for Health
  • Cardiovascular Research - Immunity and Atherosclerosis
  • Vascular Diseases - Clinical Research
  • Cardiovascular Research - Translational Studies

Publishing year

2015

Language

English

Pages

289-294

Publication/Series

Atherosclerosis

Volume

239

Issue

2

Document type

Journal article

Publisher

Elsevier

Topic

  • Cardiac and Cardiovascular Systems

Status

Published

Research group

  • Cardiovascular Research - Immunity and Atherosclerosis
  • Vascular Diseases - Clinical Research
  • Cardiovascular Research - Translational Studies

ISBN/ISSN/Other

  • ISSN: 1879-1484